| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Advances in Brief |
Institute of Genetics, Queen’s Medical Centre, University of Nottingham, Nottingham NG7 2UH [R. J. O.], and School of Life and Environmental Sciences, University Park, University of Nottingham, Nottingham NG7 2RD [M. G. H.], United Kingdom
We report here a new framework map that integrates data from 143
studies on the loss of heterozygosity/allelic imbalance in breast
cancer. Full details of these loss of heterozygosity maps can be found
at the web site (http://www.nottingham.ac.uk/
pdzmgh/loh/)
that accompanies this report. By combining results from these data, we
have also been able to highlight and identify minimum commonly deleted
regions on each chromosome. In addition to finding commonly deleted
regions at both the BRCA1 and BRCA2 loci,
which confirmed the power of the technique, 24 other regions were
identified on 16 different chromosomes.
This article has been cited by other articles:
|
|
 |
|
  A. Vaclavicek, J. L. Bermejo, R. K Schmutzler, C. Sutter, B. Wappenschmidt, A. Meindl, M. Kiechle, N. Arnold, B. H F Weber, D. Niederacher, et al. Polymorphisms in the Janus kinase 2 (JAK)/signal transducer and activator of transcription (STAT) genes: putative association of the STAT gene region with familial breast cancer Endocr. Relat. Cancer, June 1, 2007; 14(2): 267 - 277. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Li, L. Harris, H. Mamon, M. H. Kulke, W.-H. Liu, P. Zhu, and G. Mike Makrigiorgos Whole Genome Amplification of Plasma-Circulating DNA Enables Expanded Screening for Allelic Imbalance in Plasma J. Mol. Diagn., February 1, 2006; 8(1): 22 - 30. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Orita, N. Sakamoto, Y. Ajioka, T. Terai, O. Hino, N. Sato, T. Shimoda, T. Kamano, M. Tsurumaru, and H. Fujii Allelic loss analysis of early-stage flat-type colorectal tumors Ann. Onc., January 1, 2006; 17(1): 43 - 49. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. P.H.M. Jansen, J. A. Foekens, I. L. van Staveren, M. M. Dirkzwager-Kiel, K. Ritstier, M. P. Look, M. E. Meijer-van Gelder, A. M. Sieuwerts, H. Portengen, L. C.J. Dorssers, et al. Molecular Classification of Tamoxifen-Resistant Breast Carcinomas by Gene Expression Profiling J. Clin. Oncol., February 1, 2005; 23(4): 732 - 740. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. E. Ellsworth, D. L. Ellsworth, D. M. Neatrour, B. Deyarmin, S. M. Lubert, M. J. Sarachine, P. Brown, J. A. Hooke, and C. D. Shriver Allelic Imbalance in Primary Breast Carcinomas and Metastatic Tumors of the Axillary Lymph Nodes Mol. Cancer Res., February 1, 2005; 3(2): 71 - 77. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. SCHWARZENBACH, V. MULLER, N. STAHMANN, and K. PANTEL Detection and Characterization of Circulating Microsatellite-DNA in Blood of Patients with Breast Cancer Ann. N.Y. Acad. Sci., June 1, 2004; 1022(1): 25 - 32. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. L. Schlechter, Q. Yang, P. S. Larson, A. Golubeva, R. A. Blanchard, A. de Las Morenas, and C. L. Rosenberg Quantitative DNA Fingerprinting May Distinguish New Primary Breast Cancer From Disease Recurrence J. Clin. Oncol., May 15, 2004; 22(10): 1830 - 1838. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. C. Wang, M. Lin, L.-J. Wei, C. Li, A. Miron, G. Lodeiro, L. Harris, S. Ramaswamy, D. M. Tanenbaum, M. Meyerson, et al. Loss of Heterozygosity and Its Correlation with Expression Profiles in Subclasses of Invasive Breast Cancers Cancer Res., January 1, 2004; 64(1): 64 - 71. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-M. Wong, J. M.-F. Lee, Y.-P. Ching, D.-Y. Jin, and I. O.-l. Ng Genetic and Epigenetic Alterations of DLC-1 Gene in Hepatocellular Carcinoma Cancer Res., November 15, 2003; 63(22): 7646 - 7651. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Lerebours, P. Bertheau, I. Bieche, L.-F. Plassa, M.-H. Champeme, K. Hacene, C. Toulas, M. Espie, M. Marty, and R. Lidereau Two Prognostic Groups of Inflammatory Breast Cancer Have Distinct Genotypes Clin. Cancer Res., September 15, 2003; 9(11): 4184 - 4189. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. E. Ellsworth, D. L. Ellsworth, S. M. Lubert, J. Hooke, R. I. Somiari, and C. D. Shriver High-Throughput Loss of Heterozygosity Mapping in 26 Commonly Deleted Regions in Breast Cancer Cancer Epidemiol. Biomarkers Prev., September 1, 2003; 12(9): 915 - 919. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Zhu, W. Qin, H. Ehya, J. Lininger, and E. Sauter Microsatellite Changes in Nipple Aspirate Fluid and Breast Tissue from Women with Breast Carcinoma or Its Precursors Clin. Cancer Res., August 1, 2003; 9(8): 3029 - 3033. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Climent, J. A. Martinez-Climent, D. Blesa, M. J. Garcia-Barchino, R. Saez, D. Sanchez-Izquierdo, P. Azagra, A. Lluch, and J. Garcia-Conde Genomic Loss of 18p Predicts an Adverse Clinical Outcome in Patients with High-Risk Breast Cancer Clin. Cancer Res., December 1, 2002; 8(12): 3863 - 3869. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Li, Z. H. Meng, A. Sayeed, R. Shalaby, B.-M. Ljung, and S. H. Dairkee Genome-wide Allelotyping of a New in Vitro Model System Reveals Early Events in Breast Cancer Progression Cancer Res., October 15, 2002; 62(20): 5980 - 5987. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. S. Larson, A. de las Morenas, S. R. Bennett, L. A. Cupples, and C. L. Rosenberg Loss of Heterozygosity or Allele Imbalance in Histologically Normal Breast Epithelium Is Distinct from Loss of Heterozygosity or Allele Imbalance in Co-Existing Carcinomas Am. J. Pathol., July 1, 2002; 161(1): 283 - 290. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Mora, N.-K. V. Cheung, S. Oplanich, L. Chen, and W. L. Gerald Novel Regions of Allelic Imbalance Identified by Genome-wide Analysis of Neuroblastoma Cancer Res., March 1, 2002; 62(6): 1761 - 1767. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. L. Schubert, L. Hsu, L. A. Cousens, J. Glogovac, S. Self, B. J. Reid, P. S. Rabinovitch, and P. L. Porter Single Nucleotide Polymorphism Array Analysis of Flow-Sorted Epithelial Cells from Frozen Versus Fixed Tissues for Whole Genome Analysis of Allelic Loss in Breast Cancer Am. J. Pathol., January 1, 2002; 160(1): 73 - 79. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Maitra, I. I. Wistuba, C. Washington, A. K. Virmani, R. Ashfaq, S. Milchgrub, A. F. Gazdar, and J. D. Minna High-Resolution Chromosome 3p Allelotyping of Breast Carcinomas and Precursor Lesions Demonstrates Frequent Loss of Heterozygosity and a Discontinuous Pattern of Allele Loss Am. J. Pathol., July 1, 2001; 159(1): 119 - 130. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Dammann, G. Yang, and G. P. Pfeifer Hypermethylation of the CpG Island of Ras Association Domain Family 1A (RASSF1A), a Putative Tumor Suppressor Gene from the 3p21.3 Locus, Occurs in a Large Percentage of Human Breast Cancers Cancer Res., April 1, 2001; 61(7): 3105 - 3109. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Cancer Research | Clinical Cancer Research |
| Cancer Epidemiology Biomarkers & Prevention | Molecular Cancer Therapeutics |
| Molecular Cancer Research | Cancer Prevention Research |
| Cancer Prevention Journals Portal | Cancer Reviews Online |
| Annual Meeting Education Book | Meeting Abstracts Online |
