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[Cancer Research 62, 323-328, January 1, 2002]
© 2002 American Association for Cancer Research


Meeting Report

The Role of INI1 and the SWI/SNF Complex in the Development of Rhabdoid Tumors: Meeting Summary from the Workshop on Childhood Atypical Teratoid/Rhabdoid Tumors

Jaclyn A. Biegel, Ganjarn Kalpana, Erik S. Knudsen, Roger J. Packer, Charles W. M. Roberts, Carol J. Thiele, Bernard Weissman and Malcolm Smith

Department of Pediatrics, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 [J. A. B.]; Albert Einstein College of Medicine, Bronx, New York 10461 [G. K.]; University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 [E. S. K.]; Children's National Medical Center, Washington, D.C. 20010 [R. J. P.]; Dana Farber Cancer Institute, Boston, Massachusetts 02115 [C. W. M. R.]; National Cancer Institute, Bethesda, Maryland 20892 [C. J. T., M. S.]; and University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 [B. W.]

ABSTRACT

A workshop on childhood atypical teratoid/rhabdoid tumors of the central nervous system, sponsored by the National Cancer Institute and the Pediatric Brain Tumor Foundation of the United States, was held on January 29, 2001 in Bethesda, Maryland. Drs. Malcolm Smith, Jaclyn Biegel, and Roger Packer hosted the meeting. There were 22 participants from 14 institutions. The sessions were designed to review what was known about the biology and clinical behavior of rhabdoid tumors and to begin to develop treatment strategies that might be effective against this clinically aggressive group of malignancies. This report summarizes the biology sessions from the meeting. A detailed summary of the discussions regarding diagnostic studies and the roles for radiation therapy, chemotherapy, and bone marrow or stem cell transplant in the treatment of rhabdoid tumors will be published separately.




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Copyright © 2002 by the American Association for Cancer Research.