| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Regular Articles |
1 Department of Chemistry, Washington University, St. Louis, Missouri and Departments of 2 Radiology, 3 Surgery, and 4 The Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri
This report describes recent efforts to develop and apply small animal magnetic resonance imaging methods to the study of lung tumors in mice. Magnetic resonance (MR) images obtained with respiratory gating, with data collection synchronized with the respiration of the animal, allow visualization of submillimeter tumors in animals treated with a lung carcinogen. Comparison of the MR images with gross pathology of these lungs demonstrates the utility of the imaging methods for measuring tumor burden. As a noninvasive imaging modality that uses nonionizing radiation, MR is well suited to longitudinal studies aimed at understanding the factors that control the onset and development of lung tumors and their response to therapy in a wide variety of animal models.
This article has been cited by other articles:
|
|
 |
|
  J. R. Garbow, A. C. Santeford, J. R. Anderson, J. A. Engelbach, and J. M. Arbeit Magnetic Resonance Imaging Defines Cervicovaginal Anatomy, Cancer, and VEGF Trap Antiangiogenic Efficacy in Estrogen-Treated K14-HPV16 Transgenic Mice Cancer Res., October 15, 2009; 69(20): 7945 - 7952. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Wang, Z. Zhang, J. R. Garbow, D. J. Rowland, R. A. Lubet, D. Sit, F. Law, and M. You Chemoprevention of Lung Squamous Cell Carcinoma in Mice by a Mixture of Chinese Herbs Cancer Prevention Research, July 1, 2009; 2(7): 634 - 640. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. M. Carreno, J. R. Garbow, G. R. Kolar, E. N. Jackson, J. A. Engelbach, M. Becker-Hapak, L. N. Carayannopoulos, D. Piwnica-Worms, and G. P. Linette Immunodeficient Mouse Strains Display Marked Variability in Growth of Human Melanoma Lung Metastases Clin. Cancer Res., May 15, 2009; 15(10): 3277 - 3286. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. J. Serkova, Z. Van Rheen, M. Tobias, J. E. Pitzer, J. E. Wilkinson, and K. A. Stringer Utility of magnetic resonance imaging and nuclear magnetic resonance-based metabolomics for quantification of inflammatory lung injury Am J Physiol Lung Cell Mol Physiol, July 1, 2008; 295(1): L152 - L161. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. R. Garbow, M. Wang, Y. Wang, R. A. Lubet, and M. You Quantitative Monitoring of Adenocarcinoma Development in Rodents by Magnetic Resonance Imaging Clin. Cancer Res., March 1, 2008; 14(5): 1363 - 1367. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Okazaki, A. E. Gelman, J. R. Tietjens, A. Ibricevic, C. G. Kornfeld, H. J. Huang, S. B. Richardson, J. Lai, J. R. Garbow, G. A. Patterson, et al. Maintenance of Airway Epithelium in Acutely Rejected Orthotopic Vascularized Mouse Lung Transplants Am. J. Respir. Cell Mol. Biol., December 1, 2007; 37(6): 625 - 630. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. T. Shaw, D. G. Kirsch, and T. Jacks Future of Early Detection of Lung Cancer: The Role of Mouse Models Clin. Cancer Res., July 1, 2005; 11(13): 4999s - 5003s. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. P. Smith, K. E. Luker, J. R. Garbow, J. L. Prior, E. Jackson, D. Piwnica-Worms, and G. D. Luker CXCR4 Regulates Growth of Both Primary and Metastatic Breast Cancer Cancer Res., December 1, 2004; 64(23): 8604 - 8612. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Cancer Research | Clinical Cancer Research |
| Cancer Epidemiology Biomarkers & Prevention | Molecular Cancer Therapeutics |
| Molecular Cancer Research | Cancer Prevention Research |
| Cancer Prevention Journals Portal | Cancer Reviews Online |
| Annual Meeting Education Book | Meeting Abstracts Online |
