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[Cancer Research 65, 11241-11246, December 15, 2005]
© 2005 American Association for Cancer Research


Special Workshop

A Blueprint for a Human Epigenome Project: The AACR Human Epigenome Workshop

Peter A. Jones1 and Robert Martienssen2

1 University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California and 2 Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

Requests for reprints: Peter A. Jones, University of Southern California/Norris Comprehensive Cancer Center, Room NOR 83021, 1441 Eastlake Avenue, Los Angeles, CA 90089-9181. Phone: 323-865-0816; Fax: 323-865-0102; E-mail: jones_p{at}ccnt.hsc.usc.edu.

Abstract

Epigenetic processes control the packaging and function of the human genome and contribute to normal and pathologic states, including cancer. The time is ripe to undertake an international effort to identify all the chemical changes and relationships between chromatin constituents that provide function to the genetic code. A timely workshop of leading experts, convened by the American Association for Cancer Research (AACR), confirmed that the technology is at hand to begin defining human epigenomes at high resolution. (Cancer Res 2005; 65(24): 11241-6)




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