This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hruban, R. H. Articles by Tuveson, D. A. Search for Related Content PubMed PubMed Citation Articles by Hruban, R. H. Articles by Tuveson, D. A.

Pancreatic Cancer in Mice and Man: The Penn Workshop 2004

¹ Departments of Pathology and Oncology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, Maryland; Departments of ² Medicine and Gastroenterology Division and ³ Medicine and Cancer Biology, Abramson Family Cancer Research Institute, Abramson Cancer Center at the University of Pennsylvania, Philadelphia, Pennsylvania; ⁴ Department of Medicine, University of Washington School of Medicine, Seattle, Washington; ⁵ Division of Medical Oncology, University of California at San Francisco Comprehensive Cancer Center, San Francisco, California; ⁶ Cell and Developmental Biology Department, Vanderbilt Developmental Biology Program, Nashville, Tennessee

Requests for reprints: David A. Tuveson, Department of Medicine/Heme-Onc, University of Pennsylvania, 512 BRB II/III, 421 Curie Boulevard, Philadelphia, PA 19104-6160. Phone: 215-746-5560; Fax: 215-573-2486; E-mail: tuvesond{at}mail.med.upenn.edu.

A three-day conference cosponsored by the National Cancer Institute Mouse Models of Human Cancer Consortium and the Abramson Cancer Center of the University of Pennsylvania was convened on December 1, 2004, in Philadelphia, Pennsylvania. The purpose of the conference was to compare the histopathologic changes in murine models of exocrine pancreatic cancer to human disease and to discuss potential preclinical applications of these models. The participants of this international meeting included over 100 physicians and scientists with expertise in pancreatic cancer pathology, therapy, detection, and biology, and they were organized accordingly into working groups. The format of the meeting was a series of short presentations by individual participants followed by working group breakout sessions. The working groups presented their reports on the final day of the conference, and highlights of selected individual presentations and working group recommendations are summarized here and in an accompanying pathology consensus report. (Cancer Res 2006; 66(1): 14-7)

This article has been cited by other articles:

				J. P. Morton, D. S. Klimstra, M. E. Mongeau, and B. C. Lewis Trp53 Deletion Stimulates the Formation of Metastatic Pancreatic Tumors Am. J. Pathol., April 1, 2008; 172(4): 1081 - 1087. [Abstract] [Full Text] [PDF]

				M. Aichler, H. Algul, D. Behne, G. Holzlwimmer, B. Michalke, L. Quintanilla-Martinez, J. Schmidt, R. M. Schmid, and M. Brielmeier Selenium status alters tumour differentiation but not incidence or latency of pancreatic adenocarcinomas in Ela-TGF-{alpha} p53+/ mice Carcinogenesis, September 1, 2007; 28(9): 2002 - 2007. [Abstract] [Full Text] [PDF]

				H. Funahashi, M. Satake, D. Dawson, N.-A. Huynh, H. A. Reber, O. J. Hines, and G. Eibl Delayed Progression of Pancreatic Intraepithelial Neoplasia in a Conditional KrasG12D Mouse Model by a Selective Cyclooxygenase-2 Inhibitor Cancer Res., August 1, 2007; 67(15): 7068 - 7071. [Abstract] [Full Text] [PDF]

				J. P. Morton, M. E. Mongeau, D. S. Klimstra, J. P. Morris, Y. C. Lee, Y. Kawaguchi, C. V. E. Wright, M. Hebrok, and B. C. Lewis Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis PNAS, March 20, 2007; 104(12): 5103 - 5108. [Abstract] [Full Text] [PDF]

				R. D. Cardiff, M. R. Anver, G. P. Boivin, M. W. Bosenberg, R. R. Maronpot, A. A. Molinolo, A. Y. Nikitin, J. E. Rehg, G. V. Thomas, R. G. Russell, et al. Precancer in Mice: Animal Models Used to Understand, Prevent, and Treat Human Precancers Toxicol Pathol, October 1, 2006; 34(6): 699 - 707. [Abstract] [Full Text] [PDF]

				D.A. TUVESON and S.R. HINGORANI Ductal Pancreatic Cancer in Humans and Mice Cold Spring Harb Symp Quant Biol, January 1, 2005; 70(0): 65 - 72. [Abstract] [PDF]