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Cancer Innervation

(From the Laboratories of Pathology, New England Deaconess Hospital and Harvard Cancer Commission, Boston 15, Massachusetts)

Tumor blood vessel contraction in Brown-Pearce carcinoma and mouse mesothelioma (MT₈) anterior chamber transplants results from sympathetic nerve stimulation and nerve fibers within these tumors have been demonstrated.

These observations imply that functioning nerve fibers can grow into cancerous tissue. These experiments further suggest that the reported variations in rate of growth of tumors in tissues under different states of disturbed innervation may be due to vasomotor changes.