This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Smith, W. E. Search for Related Content PubMed PubMed Citation Articles by Smith, W. E.

The Tissue Transplant Technic as a Means of Testing Materials for Carcinogenic Action^{* ,}

(From the Sloan-Kettering Institute for Cancer Research, New York 21, N.Y.)

The tissue transplant technic affords a convenient means for assaying carcinogens directly against a variety of epithelial tissues.

The sensitivity of the test can be increased by addition of Scharlach R to solutions containing the carcinogen to insure incorporation of the carcinogen into the cysts formed by the implanted epithelium, and by addition of croton oil to increase the responsiveness of the tissue.

The pure substance, tricaprylin, can be advantageously used to replace olive oil as a solvent for this work.