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Cancer Research 63, , , . doi:
© 2009 American Association for Cancer Research

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Table 2 Results of tissue array immunohistochemistry of 3439 individual tumors of >100 different types for POU5F1

The organ (in alphabetic order), tumor type, number of cases studied, and positive findings are indicated

Organ Tumor Subgroup n Positive

Adrenal gland Carcinoma Adeno- 19 0
Anus Carcinoma Squamous 3 0
Brain Gliobl. multif./astrocytoma/ 46/35 0
oligodendroglioma/meningioma/ 24/46 0
PNET/ependymoma/ 17/9 0
gangioneuroma/ 7 0
medulloblastoma/estioneuroblastoma/ 4/2 0
opticus glioma/cranioph.a 1/8 0
Carotid body Glomus tumor 11 0
Cervix Carcinoma Squamous/CIS/adeno 37/7/4 0
Colon Adenoma Tubular and villous 134 0
Carcinoma Adeno- 47 0
Endometrium Carcinoma Adeno- 61 0
Sarcoma Endometrial stromal sarcoma 3 0
Esophagus Carcinoma Squamous/adeno 21/116 0
Gall bladder Carcinoma Adeno- 23 0
Glomus tumor 11 0
Kidney Carcinoma Clear cell/papillary 50/45 1/0
Chromophobic 13 0
Oncocytoma 7 0
Larynx Carcinioma Squamous 46 0
Liver Carcinoma Hepatocellular 41 0
Lung Carcinoma Adeno-/squamous/ 48/50 0/1
large cell/small cell 47/41 1/0
Lymph nodes Lymphoma Hodgkin’s 50 0
Non-Hodgkin’s high/low grade 69 0
MALT 42 0
Breast Carcinoma Lobular/ductal 42/46 0
Med./muc./tub. 27/23/26 0
Cribriform/apocrine 5/3 0
Phylloidees tumor 13 0
Mouth Carcinoma Squamous 57 0
Ovary Carcinoma Endometroid/serous mucinous 49/48/20 0
Brenner/mixed Müllerian tumor 9/6 0
Granulosa cell 7 0
Dysgerminoma 2 2
Gonadoblastoma 1 1
Pancreas Carcinoma Adeno- 47 0
Paraganglia Paraganglioma 10 0
Parathyroid Carcinoma Adeno- 20 0
Parotid gland Carcinoma Mixed 15 0
Acinic cell/mucoepithelial 5/6 0
Phaeochrom. 26 0
Penis Carcinoma Squamous 43 0
Prostate Carcinoma Adeno-, horm. (non-)refract. 200 0
PIN/BPH 24/18 0
(Small) salivary gland Pleom. adenoma 49 0
Lymphoep. lesion 5 0
Carcinoma Adenoid cystic 43 0
Acinic cell 36 0
Adenolymph. 30 0
Skin Carcinoma Squamous/basal 81/37 0
Melanoma 44 0
Merkel cell tumor 6 0
Benign Hemangioblastoma 8 0
Nevus 38 0
Appendix tumors 25 0
(Small) intestine Carcinoma Adeno- 17 0
GIST 14 0
Stomach Carcinoma Intestinal/diffuse 44/23 0
Soft tissue Benign Lipoma/fibrous histiocytoma/Schwann/ 15/58/35 0
neurofibroma/leiomyoblastoma/ 31/7 0
giant cell tumors of tendon sheet/ 29/ 0
hemangioma 17 0
Intermediate Haemangiopericytoma 8 0
Dermatofibrosarcoma protuberans 2 0
Malignant Kaposi/liposarcoma 25/26 0
Angiomyolipo./malign. Schwann. 1/8 0
Rhabdomyosarcoma/synovial sarcoma 13/3 0
Angios./fibros./alv. soft part sarc. 4/6/1 0
Epithelioid sarcoma 2 0
Testis Seminoma/nonseminoma 49/47 49/33b
Adenomatoid tumor 10 0
Thyroid Carcinoma Foll./papill./med. 42/48/36 0
Thymus Thymoma 23 0
Urinary bladder Carcinoma TCC 101 0
Small cell/squamous/adeno- 3/5/4 0
Sarcoma 7 0
Uterus Myoma 107 0
Vagina Carcinoma Squamous 5 0
Vulva Carcinoma Squamous 37 0
Various Carcinoid 48 0
Adenomatoid tumor 10 0
Mesothelioma 23 0
Controlsc 30 0

a Gliob. multif., glioblastoma multiforme; PNET, primitive neuro-ectodermal tumor; cranioph, craniopharyngioma; CIS, carcinoma in situ; MALT, mucosa associated lymphoid tissue; med, medullar; muc, mucinous; tub, tubular; horm (non-)refract, hormonal (non)refractory; angiomyolipo., angiomyoliposarcoma; malign. Schwann., malignant Schwannoma; anglo., angiosarcoma; fibros., fibrosarcoma; alv. soft part sarc., alveolar soft part sarcoma; foll., follical.

b If containing seminoma in case of combined tumors or embryonal carcinoma elements.

c Included in all seven slides: skin (n = 4); lymph node (n = 2); heart (n = 2); skeletal muscle (n = 2); smooth muscle (n = 2); myometrium (n = 2); thyroid gland (n = 2); liver (n = 2); kidney cortex (n = 2); prostate (n = 2); testis (n = 2); submand. gland (n = 2); proliferative endometrium (n = 2); gray matter cerebrum (n = 2).





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HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Cancer Research Clinical Cancer Research
Cancer Epidemiology Biomarkers & Prevention Molecular Cancer Therapeutics
Molecular Cancer Research Cancer Prevention Research
Cancer Prevention Journals Portal Cancer Reviews Online
Annual Meeting Education Book Meeting Abstracts Online