Skip to main content
  • AACR Publications
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

  • Register
  • Log in
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Focus on Computer Resources
    • 75th Anniversary
    • Meeting Abstracts
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • OnlineFirst
    • Editors' Picks
    • Citations
    • Author/Keyword
  • News
    • Cancer Discovery News
  • AACR Publications
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in

Search

  • Advanced search
Cancer Research
Cancer Research

Advanced Search

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Focus on Computer Resources
    • 75th Anniversary
    • Meeting Abstracts
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • OnlineFirst
    • Editors' Picks
    • Citations
    • Author/Keyword
  • News
    • Cancer Discovery News
Articles

The Precipitation of Serum Proteins by Acidified Sodium Orthovanadate in Neoplastic and Other Diseases

Nils Eriksen, Lester D. Ellerbrook and Stuart W. Lippincott
Nils Eriksen
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lester D. Ellerbrook
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stuart W. Lippincott
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
DOI:  Published February 1954
  • Article
  • Info & Metrics
  • PDF
Loading

Summary

A modification of Bendien's reaction between acidified sodium orthovanadate and serum has been applied to a series of 462 serum specimens, including 110 normal controls. Of six reagent mixtures of different compositions, one was found to be more sensitive than the others for the detection of abnormal sera. On the basis of an arbitrary dividing point, allowing 5 per cent falsepositive test results among the normal controls, this reagent mixture gave positive test results as follows: 86 per cent in 76 patients with malignant neoplasms but no known metastases; 96 per cent in 68 patients with malignant neoplasms and known metastases; 62 per cent in 58 patients with benign neoplasms; 67 per cent in 150 patients with miscellaneous non-neoplastic diseases. The low order of specificity speaks against use of the test for diagnostic purposes.

Footnotes

  • ↵* This work was supported by the Cancer Control Branch (now called Field Investigations and Demonstrations Branch), National Cancer Institute, United States Public Health Service.

  • Received October 16, 1953.
  • ©1954 American Association for Cancer Research.
PreviousNext
Back to top
February 1954
Volume 14, Issue 2
  • Table of Contents
  • Table of Contents (PDF)
  • Index by Author
  • Back Matter (PDF)
  • Editorial Board (PDF)

Sign up for alerts

Open full page PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Cancer Research article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
The Precipitation of Serum Proteins by Acidified Sodium Orthovanadate in Neoplastic and Other Diseases
(Your Name) has forwarded a page to you from Cancer Research
(Your Name) thought you would be interested in this article in Cancer Research.
Citation Tools
The Precipitation of Serum Proteins by Acidified Sodium Orthovanadate in Neoplastic and Other Diseases
Nils Eriksen, Lester D. Ellerbrook and Stuart W. Lippincott
Cancer Res February 1 1954 (14) (2) 145-148;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
The Precipitation of Serum Proteins by Acidified Sodium Orthovanadate in Neoplastic and Other Diseases
Nils Eriksen, Lester D. Ellerbrook and Stuart W. Lippincott
Cancer Res February 1 1954 (14) (2) 145-148;
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Info & Metrics
  • PDF
Advertisement

Related Articles

Cited By...

More in this TOC Section

  • Intersections between Blood Cell Development and Leukemia Genes
  • Genetic Control of Programmed Cell Death in the Nematode Caenorhabditis elegans
  • Core-Binding Factor: A Central Player in Hematopoiesis and Leukemia
Show more Articles
  • Home
  • Alerts
  • Feedback
Facebook  Twitter  LinkedIn  YouTube  RSS

Articles

  • Online First
  • Current Issue
  • Past Issues
  • Meeting Abstracts

Info for

  • Authors
  • Subscribers
  • Advertisers
  • Librarians
  • Reviewers

About Cancer Research

  • About the Journal
  • Editorial Board
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2018 by the American Association for Cancer Research.

Cancer Research Online ISSN: 1538-7445
Cancer Research Print ISSN: 0008-5472
Journal of Cancer Research ISSN: 0099-7013
American Journal of Cancer ISSN: 0099-7374

Advertisement