Skip to main content
  • AACR Publications
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

  • Register
  • Log in
Advertisement

Main menu

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Focus on Computer Resources
    • 75th Anniversary
    • Meeting Abstracts
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • OnlineFirst
    • Editors' Picks
    • Citations
    • Author/Keyword
  • News
    • Cancer Discovery News
  • AACR Publications
    • Cancer Discovery
    • Cancer Epidemiology, Biomarkers & Prevention
    • Cancer Immunology Research
    • Cancer Prevention Research
    • Cancer Research
    • Clinical Cancer Research
    • Molecular Cancer Research
    • Molecular Cancer Therapeutics

User menu

  • Register
  • Log in

Search

  • Advanced search
Cancer Research
Cancer Research

Advanced Search

  • Home
  • About
    • The Journal
    • AACR Journals
    • Subscriptions
    • Permissions and Reprints
    • Reviewing
  • Articles
    • OnlineFirst
    • Current Issue
    • Past Issues
    • Focus on Computer Resources
    • 75th Anniversary
    • Meeting Abstracts
  • For Authors
    • Information for Authors
    • Author Services
    • Best of: Author Profiles
    • Submit
  • Alerts
    • Table of Contents
    • OnlineFirst
    • Editors' Picks
    • Citations
    • Author/Keyword
  • News
    • Cancer Discovery News

The Effect of Irradiation on Normal and Neoplastic Brain Tissue

Bernard J. Alpers and Henry K. Pancoast
Bernard J. Alpers
1 Neurosurgical Wards and Laboratory of Doctor C. H. Frazier and the Department of Radiology in the Hospital of the University of Pennsylvania
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Henry K. Pancoast
1 Neurosurgical Wards and Laboratory of Doctor C. H. Frazier and the Department of Radiology in the Hospital of the University of Pennsylvania
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
DOI: 10.1158/ajc.1933.7 Published January 1933
  • Article
  • Info & Metrics
  • PDF
Loading

Abstract

Introduction2

The use of roentgen rays in the treatment of brain tumors has at one time or another aroused great interest both in the neurosurgeon and radiologist. At various periods more or less hopeful claims have been made for the roentgen therapy of brain tumors. Some have felt that in certain types of tumors this mode of treatment offered a real hope as against surgery. On the whole, however, the general trend has been to use roentgen therapy as an adjunct to surgical treatment, particularly in the case of gliomata which have been found on exposure to be inoperable and inaccessible. Conflicting reports have resulted from this tendency, and we are in more or less of a dilemma concerning the efficacy of the roentgen ray in prolonging the life of individuals with inoperable gliomata.

With recent advances in our knowledge of the gliomata and of their varied structure, further opportunity is offered to study the several types of tumors of this sort, in order to determine their sensitivity to roentgen rays. This is all the more important because most of our studies have been confined to a consideration of the clinical improvement following surgery and roentgen therapy without due appraisal of the actual changes to be noted in the irradiated tissue itself, changes which might be attributed to irradiation. We have attempted, therefore, in this study to determine what effects the roentgen rays have upon gliomata of different types, and at the same time to evaluate the changes wrought in the normal brain tissue in irradiated cases.

  • Copyright © 1933 American Association for Cancer Research
PreviousNext
Back to top
January 1933
Volume 17, Issue 1
  • Table of Contents
  • Index by Author

Sign up for alerts

Open full page PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Cancer Research article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
The Effect of Irradiation on Normal and Neoplastic Brain Tissue
(Your Name) has forwarded a page to you from Cancer Research
(Your Name) thought you would be interested in this article in Cancer Research.
Citation Tools
The Effect of Irradiation on Normal and Neoplastic Brain Tissue
Bernard J. Alpers and Henry K. Pancoast
The American Journal of Cancer January 1 1933 (17) (1) 7-24; DOI: 10.1158/ajc.1933.7

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
The Effect of Irradiation on Normal and Neoplastic Brain Tissue
Bernard J. Alpers and Henry K. Pancoast
The American Journal of Cancer January 1 1933 (17) (1) 7-24; DOI: 10.1158/ajc.1933.7
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Info & Metrics
  • PDF
Advertisement

Related Articles

Cited By...

  • Home
  • Alerts
  • Feedback
Facebook  Twitter  LinkedIn  YouTube  RSS

Articles

  • Online First
  • Current Issue
  • Past Issues
  • Meeting Abstracts

Info for

  • Authors
  • Subscribers
  • Advertisers
  • Librarians
  • Reviewers

About Cancer Research

  • About the Journal
  • Editorial Board
  • Permissions
  • Submit a Manuscript
AACR logo

Copyright © 2018 by the American Association for Cancer Research.

Cancer Research Online ISSN: 1538-7445
Cancer Research Print ISSN: 0008-5472
Journal of Cancer Research ISSN: 0099-7013
American Journal of Cancer ISSN: 0099-7374

Advertisement