Summary
Moderate growth inhibition was obtainable in several transplantable tumors by the feeding of β-3-thienylalanine in diets lacking phenylalanine.
The effects of β-3-thienylalanine and deoxypyridoxine were additive in inhibition of the growth of Murphy-Strum lymphosarcoma; this inhibition was further increased by testosterone, Halotestin, and Nilevar.
Small amounts of phenylpyruvate used with small doses of β-3-thienylalanine and deoxypyridoxine appeared to be of greater advantage to the host than to the tumor.
Footnotes
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↵* Supported in part by Grant No. T-53A from the American Cancer Society and previously by Research Grant No. CF-7161 from the U.S. Public Health Service.
- Received June 14, 1960.
- ©1960 American Association for Cancer Research.
November 1960
Volume 20, Issue 10
Volume 20, Issue 10
Effect of β-3-Thienylalanine and Deoxypyridoxine on the Growth of the Murphy-Sturm Lymphosarcoma
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