Summary
Data are reported on 1485 synthetic compounds which were tested in the CCNSC primary screens. Almost all of the compounds were tested in Sarcoma 180, Adenocarcinoma 755, Leukemia 1210, and KB cells in culture; some tests were also carried out in Friend virus leukemia, Lewis lung carcinoma, Human sarcoma HS1, and Ehrlich ascites. Data are reported only on compounds which have not demonstrated sufficient activity in these systems to warrant further investigation. The number of test systems in the screening program has been reduced; the reasons for the reduction are discussed.
Footnotes
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↵1 Chief, Cancer Chemotherapy National Service Center, National Cancer Institute, Public Health Service, Bethesda, Maryland 20014.
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↵2 Biologist, Screening Section, Drug Evaluation Branch, Cancer Chemotherapy National Service Center, National Cancer Institute, Public Health Service, Bethesda, Maryland 20014.
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↵3 National Library of Medicine, Public Health Service, Bethesda, Maryland 20014.
- ©1967 American Association for Cancer Research.