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Working Group III Lipid Metabolites and Intestinal Flora

Diet and Excretion of Bile Acids

Bandaru S. Reddy
Bandaru S. Reddy
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DOI:  Published September 1981
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Abstract

In recent years, salient advances have taken place in the knowledge of the interaction of diets containing high-fat and certain type of fibers and the production of bile acids potentially relevant in the etiology of colon cancer. Other studies also indicate that a high intake of certain dietary fibers, in spite of high dietary fat, not only leads to an increase in stool bulk, thus diluting carcinogens and promoters in the gut, but also modifies the metabolism of these putative substances. These studies thus suggest that both high intake of total fat and low intake of certain fibers may be necessary for the full expression of risk to colon cancer.

Footnotes

  • ↵1 Presented at the Workshop on Fat and Cancer, December 10 to 12, 1979, Bethesda, Md. Supported by USPHS Contracts CP95604 and CP85659, Grants CA12376 and CA17613 from NIH, and Grant CA16382 through the Large Bowel Cancer Program from the National Cancer Institute.

    • ©1981 American Association for Cancer Research.
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    September 1981
    Volume 41, Issue 9 Part 2
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    Diet and Excretion of Bile Acids
    Bandaru S. Reddy
    Cancer Res September 1 1981 (41) (9 Part 2) 3766-3768;

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    Diet and Excretion of Bile Acids
    Bandaru S. Reddy
    Cancer Res September 1 1981 (41) (9 Part 2) 3766-3768;
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    Working Group III Lipid Metabolites and Intestinal Flora

    • Effects of Diet on the Fecal Excretion and Bacterial Modification of Acidic and Neutral Steroids, and Implications for Colon Carcinogenesis
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    • Summary, Conclusion, and Recommendations
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    • Effects of Diet on the Fecal Excretion and Bacterial Modification of Acidic and Neutral Steroids, and Implications for Colon Carcinogenesis
    • Diet and the Human Intestinal Bacterial Flora
    • Summary, Conclusion, and Recommendations
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