Table of Contents

Articles

• Basic Sciences

  Methotrexate Levels in the Interstitial Space and Seminiferous Tubule of Rat Testis

  Riccardo Riccardi, Robert A. Vigersky, Susan Barnes, W. Archie Bleyer and David G. Poplack

  Cancer Res May 1 1982 42 (5) 1617-1619;

  
  
• Basic Sciences

  Selective Activation of Some Dihydrodiols of Several Polycyclic Aromatic Hydrocarbons to Mutagenic Products by Prostaglandin Synthetase

  Janet Guthrie, Iain G. C. Robertson, Errol Zeiger, Jeffrey A. Boyd and Thomas E. Eling

  Cancer Res May 1 1982 42 (5) 1620-1623;

  
  
• Basic Sciences

  Antitumor Activity of the 3′-Chloroethylnitrosourea Analog of Thymidine and the Prevention by Co-administered Thymidine of Lethality but Not of Anticancer Activity

  Tai-Shun Lin, Paul H. Fischer, John C. Marsh and William H. Prusoff

  Cancer Res May 1 1982 42 (5) 1624-1629;

  
  
• Basic Sciences

  Effect of Macrophages on Phorbol Ester-stimulated Comitogenesis in Bovine Lymphocytes

  Andrea M. Mastro and Karen G. Pepin

  Cancer Res May 1 1982 42 (5) 1630-1635;

  
  
• Basic Sciences

  Deceleratory Growth by a Rat Glial Tumor Line in Culture

  Philip Skehan and Susan J. Friedman

  Cancer Res May 1 1982 42 (5) 1636-1640;

  
  
• Basic Sciences

  Methotrexate Cytotoxicity for L5178Y/Asn^- Lymphoblasts: Relationship of Dose and Duration of Exposure to Tumor Cell Viability

  D. A. Keefe, Robert L. Capizzi and Seth A. Rudnick

  Cancer Res May 1 1982 42 (5) 1641-1645;

  
  
• Basic Sciences

  Cell-mediated Mutagenicity in Chinese Hamster V79 Cells of Dibenzopyrenes and Their Bay-Region Fluorine-substituted Derivatives

  Bruce S. Hass, Catherine K. McKeown, Dennis J. Sardella, Eliahu Boger, Pallab K. Ghoshal and Eliezer Huberman

  Cancer Res May 1 1982 42 (5) 1646-1649;

  
  
• Basic Sciences

  Monoclonal Antibodies Recognizing Tumor-associated Antigen of Human Ovarian Mucinous Cystadenocarcinomas

  Malaya Bhattacharya, Sunil K. Chatterjee, Joseph J. Barlow and Hiroshi Fuji

  Cancer Res May 1 1982 42 (5) 1650-1654;

  
  
• Basic Sciences

  Establishment of Methotrexate-resistant Human Acute Lymphoblastic Leukemia Cells in Culture and Effects of Folate Antagonists

  Taisuke Ohnoshi, Takao Ohnuma, Isao Takahashi, Kevin Scanlon, Barton A. Kamen and James F. Holland

  Cancer Res May 1 1982 42 (5) 1655-1660;

  
  
• Basic Sciences

  Implementation of Micromethods to Resolve Problems of Human Breast Tumor Heterogeneity in Analysis of Cyclic 3′:5′-Nucleotide Phosphodiesterase

  Elizabeth H. Larner and Charles L. Rutherford

  Cancer Res May 1 1982 42 (5) 1661-1668;

  
  
• Basic Sciences

  Immune Selection of Tumor Cell Variants in Chickens Bearing Tumors Induced by Avian Sarcoma Virus

  Mark A. Wainberg, Evelyne Israel and Margaret Yu

  Cancer Res May 1 1982 42 (5) 1669-1675;

  
  
• Basic Sciences

  Identification of Phorbol Ester Receptors in T-Cell Growth Factor-producing and -nonproducing EL4 Mouse Thymoma Cells

  Julianne J. Sando, Mary L. Hilfiker, Mark J. Piacentini and Terri M. Laufer

  Cancer Res May 1 1982 42 (5) 1676-1680;

  
  
• Basic Sciences

  Benzo(a)pyrene Phenol Production by Perfused Rat Liver and Its Inhibition by Ethanol

  Lester A. Reinke, Paul McManus, Frederick C. Kauffman and Ronald G. Thurman

  Cancer Res May 1 1982 42 (5) 1681-1685;

  
  
• Basic Sciences

  Receptor-dependent Antiproliferative Effects of Corticosteroids in Radiation-induced Fibrosarcomas and Implications for Sequential Therapy

  Paul G. Braunschweiger, Han L. Ting and Lewis M. Schiffer

  Cancer Res May 1 1982 42 (5) 1686-1691;

  
  
• Basic Sciences

  Effect of l-Phenylalanine Mustard, Adriamycin, Actinomycin D, and 4′-(9-Acridinylamino)methanesulfon-m-anisidide on Naturally Occurring Human Spontaneous Monocyte-mediated Cytotoxicity

  Eugenie S. Kleinerman, Leonard A. Zwelling, Ronald Schwartz and Andrew V. Muchmore

  Cancer Res May 1 1982 42 (5) 1692-1695;

  
  
• Basic Sciences

  Pharmacology and Toxicity of a Potent “Nonclassical” 2,4-Diamino Quinazoline Folate Antagonist, Trimetrexate, in Normal Dogs

  Eleanor C. Weir, Arlene R. Cashmore, Robert N. Dreyer, Michael L. Graham, Nina Hsiao, Barbara A. Moroson, Wendy L. Sawicki and Joseph R. Bertino

  Cancer Res May 1 1982 42 (5) 1696-1702;

  
  
• Basic Sciences

  Components of Hematoporphyrin Derivatives and Their Tumor-localizing Capacity

  David Kessel

  Cancer Res May 1 1982 42 (5) 1703-1706;

  
  
• Basic Sciences

  Toxicity and Anticancer Activity of a New Triazine Antifolate (NSC 127755)

  Thomas H. Corbett, Wilbur R. Leopold, Donald J. Dykes, Billy J. Roberts, Daniel P. Griswold Jr. and Frank M. Schabel Jr.

  Cancer Res May 1 1982 42 (5) 1707-1715;

  
  
• Basic Sciences

  Correlation between Amounts of Cellular Membrane Components and Sensitivity to Hyperthermia in a Variety of Mammalian Cell Lines in Culture

  Anne E. Cress, Patrick S. Culver, Thomas E. Moon and Eugene W. Gerner

  Cancer Res May 1 1982 42 (5) 1716-1721;

  
  
• Basic Sciences

  Effect of Microsomal Cytochrome P-450 Isozyme Induction on the Mutagenic Activation of 2-Aminoanthracene

  Richard L. Norman, Ursula Muller-Eberhard and Eric F. Johnson

  Cancer Res May 1 1982 42 (5) 1722-1726;

  
  
• Basic Sciences

  Hormonal Regulation of Net DNA Synthesis in MCF-7 Human Breast Cancer Cells in Tissue Culture

  Susan C. Aitken and Marc E. Lippman

  Cancer Res May 1 1982 42 (5) 1727-1735;

  
  
• Basic Sciences

  Influence of Tetrahydrouridine on the Pharmacokinetics of Intrathecally Administered 1-β-d-arabinofuranosylcytosine

  Riccardo Riccardi, Bruce Chabner, Daniel L. Glaubiger, James Wood and David G. Poplack

  Cancer Res May 1 1982 42 (5) 1736-1739;

  
  
• Basic Sciences

  Effects of Partially Thiolated Polycytidylic Acid and Liposomes on in Vitro Colony-forming Cells of Leukemic Mice

  Yau-Kwan Ho, Eric Mayhew, Harvey D. Preisler and Thomas J. Bardos

  Cancer Res May 1 1982 42 (5) 1740-1743;

  
  
• Basic Sciences

  Development of Thermotolerance during Fractionated Hyperthermia in a Solid Tumor in Vivo

  Toshiharu Kamura, Ole S. Nielsen, Jens Overgaard and Anders H. Andersen

  Cancer Res May 1 1982 42 (5) 1744-1748;

  
  
• Basic Sciences

  Biochemical Properties of the High-Molecular-Weight Glycopeptides Released from the Cell Surface of Human Teratocarcinoma Cells

  Hisako Muramatsu, Takashi Muramatsu and Philip Avner

  Cancer Res May 1 1982 42 (5) 1749-1752;

  
  
• Basic Sciences

  Detection of Ductal Dysplasia in Mammary Outgrowths Derived from Carcinogen-treated Virgin Female BALB/c Mice

  Stephen P. Ethier and Robert L. Ullrich

  Cancer Res May 1 1982 42 (5) 1753-1760;

  
  
• Basic Sciences

  Effect of Magnesium Content on Density-dependent Regulation of the Onset of DNA Synthesis in Transformed 3T3 Cells

  H. Rubin

  Cancer Res May 1 1982 42 (5) 1761-1768;

  
  
• Basic Sciences

  Effect of cis- and trans-Dichlorodiammineplatinum(II) on Human Tumor Cell Proliferation in Diffusion Chambers in Vivo

  Kathleen R. Ambrose and Jon S. Lowrey

  Cancer Res May 1 1982 42 (5) 1769-1773;

  
  
• Basic Sciences

  Inhibition of Methylazoxymethanol-induced Intestinal Tumors in the Rat by Pyrazole with Paradoxical Effects on Skin and Kidney

  James Notman, Queng Hui Tan and Morris S. Zedeck

  Cancer Res May 1 1982 42 (5) 1774-1780;

  
  
• Basic Sciences

  Enhanced Effect of Gastrin on Rat Stomach Carcinogenesis Induced by N-Methyl-N′-nitro-N-nitrosoguanidine

  Eiichi Tahara, Fumio Shimamoto, Kyohiko Taniyama, Hisao Ito, Yasutoshi Kosako and Hiromichi Sumiyoshi

  Cancer Res May 1 1982 42 (5) 1781-1787;

  
  
• Basic Sciences

  Characterization of Growth-inhibitory Activities Associated with an α-Macroglobulin of Mice

  Peter H. Koo

  Cancer Res May 1 1982 42 (5) 1788-1797;

  
  
• Basic Sciences

  Monoclonal Antibodies That Inhibit Enzyme Activity of 3-Methylcholanthrene-induced Cytochrome P-450

  Sang S. Park, Tadahiko Fujino, Donna West, F. Peter Guengerich and Harry V. Gelboin

  Cancer Res May 1 1982 42 (5) 1798-1808;

  
  
• Basic Sciences

  Correlation between the Rates of Aerobic Glycolysis and Glucose Transport, Unrelated to Neoplastic Transformation, in a Series of BALB 3T3-derived Cell Lines

  Beverly Peterkofsky and Willie Prather

  Cancer Res May 1 1982 42 (5) 1809-1816;

  
  
• Basic Sciences

  Doxorubicin-induced Chronic Cardiotoxicity and Its Protection by Liposomal Administration

  Aquilur Rahman, Newton More and Philip S. Schein

  Cancer Res May 1 1982 42 (5) 1817-1825;

  
  
• Basic Sciences

  Transepithelial Invasion and Intramesenchymal Infiltration of the Chick Embryo Chorioallantois by Tumor Cell Lines

  Peter B. Armstrong, James P. Quigley and Eric Sidebottom

  Cancer Res May 1 1982 42 (5) 1826-1837;

  
  
• Basic Sciences

  Homogeneously Staining Regions in Direct Preparations from Human Neuroblastomas

  Gloria Balaban and Fred Gilbert

  Cancer Res May 1 1982 42 (5) 1838-1842;

  
  
• Basic Sciences

  Conversion of Malignant Murine Embryonal Carcinomas to Benign Teratomas by Chemical Induction of Differentiation in Vivo

  Wendell C. Speers

  Cancer Res May 1 1982 42 (5) 1843-1849;

  
  
• Basic Sciences

  Inhibition of Cellular Division of a Murine Macrophage Tumor by Macrophage-activating Agents

  James E. Talmadge, Patricia A. Donovan and Ian R. Hart

  Cancer Res May 1 1982 42 (5) 1850-1855;

  
  
• Basic Sciences

  Evidence for Single-Cell Origin of 3-Methylcholanthrene-induced Fibrosarcomas in Mice with Cellular Mosaicism

  Hiroshi Tanooka and Kazuhiko Tanaka

  Cancer Res May 1 1982 42 (5) 1856-1858;

  
  
• Basic Sciences

  Metabolism of Benzo(a)pyrene in Epidermal Keratinocytes and Dermal Fibroblasts of Humans and Mice with Reference to Variation among Species, Individuals, and Cell Types

  Toshio Kuroki, Jiro Hosomi, Kimiyo Munakata, Takuya Onizuka, Masami Terauchi and Nobuo Nemoto

  Cancer Res May 1 1982 42 (5) 1859-1865;

  
  
• Basic Sciences

  Induction of Cytotoxicity, Mutation, Cytogenetic Changes, and Neoplastic Transformation by Benzo(a)pyrene and Derivatives in C3H/10T½ Clone 8 Mouse Fibroblasts

  Eugene B. Gehly, Joseph R. Landolph, Charles Heidelberger, Hatsumi Nagasawa and John B. Little

  Cancer Res May 1 1982 42 (5) 1866-1875;

  
  
• Basic Sciences

  Inhibition of Mitochondrial Protein Synthesis during Early Stages of Aflatoxin B₁-induced Hepatocarcinogenesis

  Narayan K. Bhat, John K. Emeh, Banavadi G. Niranjan and Narayan G. Avadhan

  Cancer Res May 1 1982 42 (5) 1876-1880;

  
  
• Basic Sciences

  Dome Formation by a Retrovirus-induced Lung Adenocarcinoma Cell Line

  Angie Rizzino, Matthew A. Gonda and Ulf R. Rapp

  Cancer Res May 1 1982 42 (5) 1881-1887;

  
  
• Basic Sciences

  Protective Effects of S-2-(3-Aminopropylamino)ethylphosphorothioic Acid against Radiation Damage of Normal Tissues and a Fibrosarcoma in Mice

  Luka Milas, Nancy Hunter, Betty O. Reid and Howard D. Thames Jr.

  Cancer Res May 1 1982 42 (5) 1888-1897;

  
  
• Basic Sciences

  Arrest and Retention of Circulating Cancer Cells in the Lungs of Animals with Defined Metastatic Status

  Leonard Weiss and Pamela M. Ward

  Cancer Res May 1 1982 42 (5) 1898-1903;

  
  
• Basic Sciences

  Variants of an Interspecies Hybridoma with Altered Tumorigenicity and Protective Ability against Mouse Myeloma Tumors

  R. Baumal, E. Musclow, H. Farkas-Himsley and A. Marks

  Cancer Res May 1 1982 42 (5) 1904-1908;

  
  
• Basic Sciences

  Induction of Sister Chromatid Exchange by Polyoma Large Viral Tumor Antigen in Transformed Rat Fibroblasts

  Eric H. Brown and Claudio Basilico

  Cancer Res May 1 1982 42 (5) 1909-1912;

  
  
• Basic Sciences

  Heterogeneity of Binding Sites for Tamoxifen and Tamoxifen Derivatives in Estrogen Target and Nontarget Fetal Organs of Guinea Pig

  Alberto Gulino and Jorge Raul Pasqualini

  Cancer Res May 1 1982 42 (5) 1913-1921;

  
  
• Basic Sciences

  Involvement of T-Lymphocytes in the Stimulatory Effects of EMT₆ Tumors on Medullary Pluripotent Stem Cells of BALB/c Mice

  Marie-Pierre Fache, Françoise Lepault and Emilia Frindel

  Cancer Res May 1 1982 42 (5) 1922-1926;

  
  
• Basic Sciences

  Monoclonal Antibody against a Membrane Antigen Characterizing Leukemic Human B-Lymphocytes

  Hansjörg K. Forster, Fred G. Gudat, Marie-F. Girard, Renate Albrecht, Jörg Schmidt, Christian Ludwig and Jean-P. Obrecht

  Cancer Res May 1 1982 42 (5) 1927-1934;

  
  
• Basic Sciences

  Partial Characterization and “Quantitation” of a Human Prostatic Estramustine-binding Protein

  Per Björk, Björn Forsgren, Jan-Åke Gustafsson, Åke Pousette and Bertil Högberg

  Cancer Res May 1 1982 42 (5) 1935-1942;

  
  
• Basic Sciences

  Effect of X-Rays and Cyclophosphamide on Solid Tumors and Naturally Occurring Metastases in Mice

  Ann M. Chu and Jack F. Fowler

  Cancer Res May 1 1982 42 (5) 1943-1949;

  
  
• Basic Sciences

  Uptake, Efflux, and Hydrolysis of Aclacinomycin A in Friend Leukemia Cells

  Alain Fourcade, Jean-Jacques Farhi, Myriam Bennoun and Haim Tapiero

  Cancer Res May 1 1982 42 (5) 1950-1954;

  
  
• Basic Sciences

  Copper- and Zinc-containing Superoxide Dismutase, Manganese-containing Superoxide Dismutase, Catalase, and Glutathione Peroxidase in Normal and Neoplastic Human Cell Lines and Normal Human Tissues

  Stefan L. Marklund, N. Gunnar Westman, Erik Lundgren and Göran Roos

  Cancer Res May 1 1982 42 (5) 1955-1961;

  
  
• Basic Sciences

  Nondetection of O⁶-Methylguanine in Rat DNA following in Vivo Treatment with Large Doses of Cimetidine Alone or in Combination with Sodium Nitrite

  Soterios A. Kyrtopoulos, Efstathios Hadjiloucas and Birgitta Vrotsou

  Cancer Res May 1 1982 42 (5) 1962-1966;

  
  
• Basic Sciences

  Estrone Receptor Formation During the Processing of Estradiol-Receptor Complex in MCF-7 Cells

  E. R. Hansen and S. C. Brooks

  Cancer Res May 1 1982 42 (5) 1967-1974;

  
  
• Basic Sciences

  Effects of Phorbol Esters on Basal Epidermal Cells Derived from Ear Skin of Adult Guinea Pigs

  C. Delescluse, G. Fürstenberger, F. Marks and M. Pruniéras

  Cancer Res May 1 1982 42 (5) 1975-1979;

  
  
• Basic Sciences

  Tumor Promoter Stimulation of Phosphatidylcholine Turnover in HeLa Cells

  Graeme R. Guy and Andrew W. Murray

  Cancer Res May 1 1982 42 (5) 1980-1985;

  
  
• Basic Sciences

  Polysomal Polyadenylated RNA and Albumin Messenger RNA in Mastomys Liver and in a Chemically Induced Hepatocellular Carcinoma

  Liselotte Krieg, Detlev Krause-Leipholdt, Klaus Wayss and Manfred Volm

  Cancer Res May 1 1982 42 (5) 1986-1993;

  
  
• Basic Sciences

  Loss of Melanogenic Properties in Tyrosinases Induced by Glycosylation Inhibitors within Malignant Melanoma Cells

  Genji Imokawa and Yutaka Mishima

  Cancer Res May 1 1982 42 (5) 1994-2002;

  
  
• Basic Sciences

  Vaginal Adenosis and Adenocarcinoma in Mice Exposed Prenatally or Neonatally to Diethylstilbestrol

  Retha R. Newbold and John A. McLachlan

  Cancer Res May 1 1982 42 (5) 2003-2011;

  
  
• Basic Sciences

  Immunochemical Differences among Carcinoembryonic Antigen in Tumor Tissues and Related Antigens in Meconium and Adult Feces

  Yuji Matsuoka, Masahida Kuroki, Yoshiko Koga, Hiroshi Kuriyama, Takesada Mori and Goro Kosaki

  Cancer Res May 1 1982 42 (5) 2012-2018;

  
  
• Basic Sciences

  Biosynthesis of an Interstitial Type of Collagen by Cloned Human Gastric Carcinoma Cells

  Kooko Sakakibara, Toshimitsu Suzuki, Teiichi Motoyama, Hidenobu Watanabe and Yoshitaka Nagai

  Cancer Res May 1 1982 42 (5) 2019-2027;

  
  
• Basic Sciences

  Monoclonal Antibodies in Analysis of Oncoplacental Protein SP₁ in Vivo and in Vitro

  Eva Engvall, Masato Miyashita and Erkki Ruoslahti

  Cancer Res May 1 1982 42 (5) 2028-2033;

  
  
• Basic Sciences

  Histological, Proliferative, and Biochemical Alterations in Dorsal Epidermis of the Syrian Golden Hamster Induced by 12-O-Tetradecanoylphorbol-13-acetate and the Calcium Ionophore A 23187

  Friedhelm Hasper, Gerhard Müller and Jürgen Schweizer

  Cancer Res May 1 1982 42 (5) 2034-2039;

  
  
• Basic Sciences

  Establishment and Characterization of SV40-transformed Human Breast Epithelial Cell Lines

  Sidney E. Chang, Jacqueline Keen, E. Birgitte Lane and Joyce Taylor-Papadimitriou

  Cancer Res May 1 1982 42 (5) 2040-2053;

  
  
• Clinical Investigations

  Diphtheria Toxin Treatment of Human Advanced Cancer

  Silvio Buzzi

  Cancer Res May 1 1982 42 (5) 2054-2058;

  
  
• Clinical Investigations

  A Phase I Study of Intracarotid Artery Infusion of cis-Diamminedichloroplatinum(II) in Patients with Recurrent Malignant Intracerebral Tumors

  David J. Stewart, Sidney Wallace, Lynn Feun, Milam Leavens, Sue Ellen Young, Stanley Handel, Giora Mavligit and Robert S. Benjamin

  Cancer Res May 1 1982 42 (5) 2059-2062;

  
  
• Clinical Investigations

  Natural Killer Activity in Spleens and Lymph Nodes from Patients with Hodgkin's Disease

  Luigi P. Ruco, Antonio Procopio, Stefania Uccini, Enrico Marcorelli and Carlo D. Baroni

  Cancer Res May 1 1982 42 (5) 2063-2068;

  
  
• Clinical Investigations

  Pharmacology of 13-cis-Retinoic Acid in Humans

  Ian G. Kerr, Marc E. Lippman, Jean Jenkins and Charles E. Myers

  Cancer Res May 1 1982 42 (5) 2069-2073;

  
  
• Clinical Investigations

  Response to Luteinizing Releasing Hormone, Thyrotrophic Releasing Hormone, and Human Chorionic Gonadotrophin Administration in Health Men at Different Risks for Prostatic Cancer and in Prostatic Cancer Patients

  P. Hill, E. L. Wynder, L. Garbaczewski, H. Garnes and A. R. P. Walker

  Cancer Res May 1 1982 42 (5) 2074-2080;

  
  
• Clinical Investigations

  Optimal Scheduling of Methotrexate and 5-Fluorouracil in Human Breast Cancer

  Chris Benz, Tina Tillis, Ellen Tattelman and Ed Cadman

  Cancer Res May 1 1982 42 (5) 2081-2086;

  
  
• Clinical Investigations

  Pharmacokinetics of 13-cis-Retinoic Acid in Patients with Advanced Cancer

  Gary E. Goodman, Janine G. Einspahr, David S. Alberts, Thomas P. Davis, Susan A. Leigh, H. S. George Chen and Frank L. Meyskens

  Cancer Res May 1 1982 42 (5) 2087-2091;

  
  
• Clinical Investigations

  Modulation of 9-β-d-Arabinofuranosyladenine 5′-Triphosphate and Deoxyadenosine Triphosphate in Leukemic Cells by 2′-Deoxycoformycin during Therapy with 9-β-d-Arabinofuranosyladenine

  William Plunkett, Robert S. Benjamin, Michael J. Keating and Emil J Freireich

  Cancer Res May 1 1982 42 (5) 2092-2096;

  
  
• Letter to the Editor

  Urinary Excretion of Monoacetyl Polyamines in Patients with Non-Hodgkin's Lymphoma

  Mahmoud M. Abdel-Monem, James L. Merdink and Athanasios Theologides

  Cancer Res May 1 1982 42 (5) 2097-2098;

  
  
• Meeting Report

  Modified Nucleosides and Cancer

  Ernest Borek

  Cancer Res May 1 1982 42 (5) 2099-2100;

  
  
• Articles

  Announcements

  Cancer Res May 1 1982 42 (5) 2101-2101;

  
  
• Erratum

  Enhanced Inhibition of Mammary Carcinogenesis by Combined Treatment with N-(4-Hydroxyphenyl)retinamide and Ovariectomy.

  Cancer Res May 1 1982 42 (5) 2102-2102;

  
  
• Erratum

  Effects of Tocopherol (Vitamin E) Acid Succinate on Morphological Alterations and Growth Inhibition in Melanoma Cells in Culture.

  Cancer Res May 1 1982 42 (5) 2102-2102;