Table of Contents

Articles

• Advances in Brief

  Transgenic Mouse Model for Synergistic Effects of Nuclear Oncogenes and Growth Factors in Tumorigenesis: Interaction of c-myc and Transforming Growth Factor α in Hepatic Oncogenesis

  Hiroko Murakami, Nancy D. Sanderson, Peter Nagy, Pamela A. Marino, Glenn Merlino and Snorri S. Thorgeirsson

  Cancer Res April 15 1993 53 (8) 1719-1723;

  
  
• Advances in Brief

  Immunohistochemical Localization of Parathyroid Hormone-related Protein in Human Prostate Cancer

  Masatsugu Iwamura, P. Anthony di Sant'Agnese, Guan Wu, Cynthia M. Benning, Abraham T. K. Cockett, Leonard J. Deftos and Per-Anders Abrahamsson

  Cancer Res April 15 1993 53 (8) 1724-1726;

  
  
• Advances in Brief

  In Vivo Inhibition of Insulin-like Growth Factor I Gene Expression by Tamoxifen

  Hung T. Huynh, Evelyn Tetenes, Laurie Wallace and Michael Pollak

  Cancer Res April 15 1993 53 (8) 1727-1730;

  
  
• Advances in Brief

  Ribozyme-mediated Modulation of Human O⁶-Methylguanine-DNA Methyltransferase Expression

  Philip M. Potter, Linda C. Harris, Joanna S. Remack, Carol C. Edwards and Thomas P. Brent

  Cancer Res April 15 1993 53 (8) 1731-1734;

  
  
• Advances in Brief

  Activation of the Abelson Tyrosine Kinase Activity Is Associated with Suppression of Apoptosis in Hemopoietic Cells

  Caroline A. Evans, P. Jane Owen-Lynch, Anthony D. Whetton and Caroline Dive

  Cancer Res April 15 1993 53 (8) 1735-1738;

  
  
• Advances in Brief

  A Structural Role for Metal Ions in the “Wild-type” Conformation of the Tumor Suppressor Protein p53

  Pierre Hainaut and Jo Milner

  Cancer Res April 15 1993 53 (8) 1739-1742;

  
  
• Advances in Brief

  Prevention of Orthotopic Human Lung Cancer Growth by Intratracheal Instillation of a Retroviral Antisense K-ras Construct

  Renee N. Georges, Tapas Mukhopadhyay, Yujiao Zhang, Nancy Yen and Jack A. Roth

  Cancer Res April 15 1993 53 (8) 1743-1746;

  
  
• Advances in Brief

  Analysis of the Expression of MRP, the Gene for a New Putative Transmembrane Drug Transporter, in Human Multidrug Resistant Lung Cancer Cell Lines

  Guido J. R. Zaman, Carolina H. M. Versantvoort, Jaap J. M. Smit, Elisabeth W. H. M. Eijdems, Marcel de Haas, Alexander J. Smith, Henricus J. Broxterman, Nanno H. Mulder, Elisabeth G. E. de Vries, Frank Baas and Piet Borst

  Cancer Res April 15 1993 53 (8) 1747-1750;

  
  
• Biochemistry and Biophysics

  Identification of a Putative Tumor Marker in Breast and Colon Cancer

  Bangying Su, Francis Kappler, Benjamin S. Szwergold and Truman R. Brown

  Cancer Res April 15 1993 53 (8) 1751-1754;

  
  
• Biochemistry and Biophysics

  Entry of Protein Toxins in Polarized Epithelial Cells

  Elisabeth L. Melby, Jorunn Jacobsen, Sjur Olsnes and Kirsten Sandvig

  Cancer Res April 15 1993 53 (8) 1755-1760;

  
  
• Carcinogenesis

  Chromatophoromas and Chromatophore Hyperplasia in Pacific Rockfish (Sebastes spp.)

  Mark S. Okihiro, Jeannette A. Whipple, Joseph M. Groff and David E. Hinton

  Cancer Res April 15 1993 53 (8) 1761-1769;

  
  
• Carcinogenesis

  Loss of Differentiation Control in Transformed 3T3 T Proadipocytes

  Rodney L. Sparks, Blake J. Allen, Andrea I. Zygmunt and Ethan E. Strauss

  Cancer Res April 15 1993 53 (8) 1770-1776;

  
  
• Carcinogenesis

  Induction of Neoplastic Progression in Syrian Hamster Embryo Cells Treated with Protein Phosphatase Inhibitors

  Cynthia A. Afshari, Seiji Kodama, Holly M. Bivins, T. Brian Willard, Hirota Fujiki and J. Carl Barrett

  Cancer Res April 15 1993 53 (8) 1777-1782;

  
  
• Carcinogenesis

  Accumulation of p53 Protein in Human Esophageal Precancerous Lesions: A Possible Early Biomarker for Carcinogenesis

  Li-Dong Wang, Jun-Yan Hong, Song-Liang Qiu, Hongkun Gao and Chung S. Yang

  Cancer Res April 15 1993 53 (8) 1783-1787;

  
  
• Clinical Investigations

  Clinical Value of Determination of Urokinase-type Plasminogen Activator Antigen in Plasma for Detection of Colorectal Cancer: Comparison with Circulating Tumor-associated Antigens CA 19-9 and Carcinoembryonic Antigen

  Kurt Huber, Johannes C. Kirchheimer, Astrid Sedlmayer, Cameron Bell, Dorothea Ermler and Bernd R. Binder

  Cancer Res April 15 1993 53 (8) 1788-1793;

  
  
• Clinical Investigations

  Phase I and Pharmacological Study of the Pulmonary Cytotoxin 4-Ipomeanol on a Single Dose Schedule in Lung Cancer Patients: Hepatotoxicity Is Dose Limiting in Humans

  Eric K. Rowinsky, Dennis A. Noe, David S. Ettinger, Michaele C. Christian, Barbara G. Lubejko, Elliot K. Fishman, Susan E. Sartorius, Michael R. Boyd and Ross C. Donehower

  Cancer Res April 15 1993 53 (8) 1794-1801;

  
  
• Endocrinology

  Characterization of the Aryl Hydrocarbon Receptor and Aryl Hydrocarbon Responsiveness in Human Ovarian Carcinoma Cell Lines

  C. Rowlands, V. Krishnan, X. Wang, M. Santostefano, S. Safe, W. R. Miller and S. Langdon

  Cancer Res April 15 1993 53 (8) 1802-1807;

  
  
• Endocrinology

  Glucocorticoids Coordinately Disrupt a Transforming Growth Factor α Autocrine Loop and Suppress the Growth of 13762NF-derived Con8 Rat Mammary Adenocarcinoma Cells

  David B. Alexander, Luis Goya, Melanie K. Webster, Tokuko Haraguchi and Gary L. Firestone

  Cancer Res April 15 1993 53 (8) 1808-1815;

  
  
• Endocrinology

  Overexpression of Transforming Growth Factor α Overrides the Glucocorticoid-mediated Suppression of Con8 Mammary Tumor Cell Growth in Vitro and in Vivo

  Luis Goya, Dave B. Alexander, Melanie K. Webster, Francis G. Kern, Raphael C. Guzman, Satyabrata Nandi and Gary L. Firestone

  Cancer Res April 15 1993 53 (8) 1816-1822;

  
  
• Endocrinology

  Ovarian Cancers Express and Process Progastrin

  Wouter W. van Solinge, Lars Ødum and Jens F. Rehfeld

  Cancer Res April 15 1993 53 (8) 1823-1828;

  
  
• Experimental Therapeutics

  Modulation of Both Cisplatin Nephrotoxicity and Drug Resistance in Murine Bladder Tumor by Controlling Metallothionein Synthesis

  Masahiko Satoh, Debra M. Kloth, Salam A. Kadhim, Joseph L. Chin, Akira Naganuma, Nobumasa Imura and M. George Cherian

  Cancer Res April 15 1993 53 (8) 1829-1832;

  
  
• Experimental Therapeutics

  Antiangiogenic Effects of the Quinoline-3-Carboxamide Linomide

  Jasminka Vukanovic, Antonino Passaniti, Takahiko Hirata, Richard J. Traystman, Beryl Hartley-Asp and John T. Isaacs

  Cancer Res April 15 1993 53 (8) 1833-1837;

  
  
• Experimental Therapeutics

  Protection of Bone Marrow Stromal Cells from the Toxic Effects of Cyclophosphamide in Vivo and of ASTA-Z 7557 and Etoposide in Vitro by Ammonium Trichloro(dioxyethylene-O-O′)tellurate (AS101)

  Yona Kalechman, Iris Sotnik-Barkai, Michael Albeck and Benjamin Sredni

  Cancer Res April 15 1993 53 (8) 1838-1844;

  
  
• Experimental Therapeutics

  Apoptosis Induced by Anthracycline Antibiotics in P388 Parent and Multidrug-resistant Cells

  Yi-He Ling, Waldemar Priebe and Roman Perez-Soler

  Cancer Res April 15 1993 53 (8) 1845-1852;

  
  
• Experimental Therapeutics

  Constitutive Expression of Human Bcl-2 Modulates Nitrogen Mustard and Camptothecin Induced Apoptosis

  M. I. Walton, D. Whysong, P. M. O'Connor, D. Hockenbery, S. J. Korsmeyer and K. W. Kohn

  Cancer Res April 15 1993 53 (8) 1853-1861;

  
  
• Experimental Therapeutics

  Inhibition of Protein Tyrosine Phosphatase by the Antitumor Agent Gallium Nitrate

  Margareta M. Berggren, Leigh Ann Burns, Robert T. Abraham and Garth Powis

  Cancer Res April 15 1993 53 (8) 1862-1866;

  
  
• Experimental Therapeutics

  Yeast Cells Can Enter a Quiescent State through G₁, S, G₂, or M Phase of the Cell Cycle

  Wen Wei, Paul Nurse and Daniel Broek

  Cancer Res April 15 1993 53 (8) 1867-1870;

  
  
• Immunology

  Human Myelomonocytic Cell Line THP-1 Produces a Novel Growth-promoting Factor with a Wide Target Cell Spectrum

  Akihiko Takeuchi, Hidetoshi Hayashi, Yukiko Naito, Tohru Baba, Takuya Tamatani and Kikuo Onozaki

  Cancer Res April 15 1993 53 (8) 1871-1876;

  
  
• Molecular Biology and Genetics

  An Anticancer Drug-sensitive Murine Erythroleukemia Clone: Implications for the Mechanism of Action of Antineoplastic Drugs

  Richard D. Dinnen, Carl F. Robinow and Kaney Ebisuzaki

  Cancer Res April 15 1993 53 (8) 1877-1882;

  
  
• Molecular Biology and Genetics

  Alterations of the p53 Tumor Suppressor Gene and Its Association with Activation of the c-K-ras-2 Protooncogene in Premalignant and Malignant Lesions of the Human Uterine Endometrium

  Takayuki Enomoto, Masami Fujita, Masaki Inoue, Jerry M. Rice, Ryuichi Nakajima, Osamu Tanizawa and Taisei Nomura

  Cancer Res April 15 1993 53 (8) 1883-1888;

  
  
• Molecular Biology and Genetics

  Altered Messenger RNA and Unique Mutational Profiles of p53 and Rb in Human Esophageal Carcinomas

  Ying Huang, Stephen J. Meltzer, Jing Yin, Yi Tong, Esther H. Chang, Shiv Srivastava, Tim McDaniel, Robert F. Boynton and Zhi-Qiang Zou

  Cancer Res April 15 1993 53 (8) 1889-1894;

  
  
• Molecular Biology and Genetics

  Deletion of 1p36 as a Primary Chromosomal Aberration in Intestinal Tumorigenesis

  Georgia Bardi, Nikos Pandis, Claus Fenger, Ole Kronborg, Lilian Bomme and Sverre Heim

  Cancer Res April 15 1993 53 (8) 1895-1898;

  
  
• Molecular Biology and Genetics

  Ultrastructural Localization and Fluctuation in the Level of the Proliferating Cell Nuclear Antigen and myc Oncoproteins in Synchronized Neuroblastoma Cells

  Yair Gazitt, Gregory W. Erdos and Robert J. Cohen

  Cancer Res April 15 1993 53 (8) 1899-1905;

  
  
• Molecular Biology and Genetics

  Mutation of the Ki-ras Protooncogene in Human Endometrial Hyperplasia and Carcinoma

  Hiroshi Sasaki, Hiroshi Nishii, Hiroyuki Takahashi, Akio Tada, Masakuni Furusato, Yoshiteru Terashima, Gene P. Siegal, Sheryl L. Parker, Matthew F. Kohler, Andrew Berchuck and Jeff Boyd

  Cancer Res April 15 1993 53 (8) 1906-1910;

  
  
• Tumor Biology

  Receptor for Urokinase Is Present in Tumor-associated Macrophages in Ductal Breast Carcinoma

  C. Pyke, N. Græm, E. Ralfkiær, E. Rønne, G. Høyer-Hansen, N. Brünner and K. Danø

  Cancer Res April 15 1993 53 (8) 1911-1915;

  
  
• Tumor Biology

  Ubiquitin-Ribosomal Protein S27a Gene Overexpressed in Human Colorectal Carcinoma Is an Early Growth Response Gene

  Jau Min Wong, Ken-ichi Mafune, Hsiukang Yow, Elissa N. Rivers, T. S. Ravikumar, Glenn D. Steele Jr. and Lan Bo Chen

  Cancer Res April 15 1993 53 (8) 1916-1920;

  
  
• Tumor Biology

  Enhanced Immunosuppressive Activity Associated with Metastatic Lymphoma Cells

  Weimin Hao, Thomas L. McDonald, Kenneth W. Brunson and Shantaram S. Joshi

  Cancer Res April 15 1993 53 (8) 1921-1928;

  
  
• Tumor Biology

  Wild-type Adenovirus Type 5 Transforming Genes Function as Transdominant Suppressors of Oncogenesis in Mutant Adenovirus Type 5 Transformed Rat Embryo Fibroblast Cells

  Zao-Zhong Su, Jorge A. Leon, Hongping Jiang, Vincent N. Austin, Stephen G. Zimmer and Paul B. Fisher

  Cancer Res April 15 1993 53 (8) 1929-1938;

  
  
• Tumor Biology

  Tumor Necrosis Factor α as an Autocrine and Paracrine Growth Factor for Ovarian Cancer: Monokine Induction of Tumor Cell Proliferation and Tumor Necrosis Factor α Expression

  S. Wu, C. M. Boyer, R. S. Whitaker, A. Berchuck, J. R. Wiener, J. B. Weinberg and R. C. Bast Jr.

  Cancer Res April 15 1993 53 (8) 1939-1944;

  
  
• Tumor Biology

  Detection of DNA Strand Breaks in Individual Apoptotic Cells by the in Situ Terminal Deoxynucleotidyl Transferase and Nick Translation Assays

  Wojciech Gorczyca, Jianping Gong and Zbigniew Darzynkiewicz

  Cancer Res April 15 1993 53 (8) 1945-1951;

  
  
• Tumor Biology

  Radiation-enhanced Expression of Major Histocompatibility Complex Class I Antigen H-2D^b in B16 Melanoma Cells

  Stephen H. Hauser, Lido Calorini, David E. Wazer and Sebastiano Gattoni-Celli

  Cancer Res April 15 1993 53 (8) 1952-1955;

  
  
• Tumor Biology

  Amplification of c-myc but not of c-erbB-2 Is Associated with High Proliferative Capacity in Breast Cancer

  H. Kreipe, H. Feist, L. Fischer, J. Felgner, K. Heidorn, L. Mettler and R. Parwaresch

  Cancer Res April 15 1993 53 (8) 1956-1961;

  
  
• Articles

  Announcements

  Cancer Res April 15 1993 53 (8) 1962-1963;

  
  
• Articles

  Recent Deaths

  Cancer Res April 15 1993 53 (8) 1963-1963;

  
  
• Articles

  Calendar of Events

  Cancer Res April 15 1993 53 (8) 1964-1964;