In the article on human bone marrow–derived mesenchymal stem cells and gliomas in the April 15, 2005 issue of Cancer Research ( 1), Fig. 6C did not indicate that the middle figure was a montage created from five individual photomicrographs taken from regions between the stem cell injection site and the implanted tumor xenograft. For illustration purposes, the individual figures were postprocessed to highlight the red stem cells and the individual photomicrographs were placed on a black background, giving the incorrect impression that this was a single image. These data acquisition methods were not described in the figure legend or in Materials and Methods. Any manipulation of scientific illustrations is inconsistent with both previous journal standards and recently defined standards for electronic image collection, compilation, and alteration ( 2), and is not acceptable.
The authors have now corrected the figure to show the five individual photomicrographs, thereby eliminating the montage; the authors also have revised the figure legend. The new figure is free of any postprocessing, except where red and green images were merged with each other. This corrected version of the figure appears below. The authors note that the correction does not alter their conclusion that hMSCs are capable of migrating toward the tumor after intracranial injection.
- ©2006 American Association for Cancer Research.