More articles from Molecular and Cellular Biology, Genetics

Abstract LB-333: Lymphatic endothelium increases antioxidant capacity of triple-negative breast cancer cells and protects from cell death
Mirela Berisa, Simona Podgrabinska, Jerry Chipuk, Mihaela Skobe

Cancer Research Jul 2017, 77 (13 Supplement) LB-333; DOI: 10.1158/1538-7445.AM2017-LB-333
Abstract LB-288: An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED
Wei Qi, Kehao Zhao, Justin Gu, Ying Huang, Youzhen Wang, Hailong Zhang, Man Zhang, Jeff Zhang, Zhengtian Yu, Ling Li, Lin Teng, Shannon Chuai, Chao Zhang, Mengxi Zhao, HoMan Chan, Zijun Chen, Douglas Fang, Fei Qi, Leying Feng, Lijian Feng, Yuan Gao, Hui Ge, Xinjian Ge, Andreas Lingel, Guobin Li, Ying Lin, Yueqin Liu, Fangjun Luo, Minlong Shi, Long Wang, Zhaofu Wang, Yanyan Yu, Jue Zeng, Chenhui Zeng, Lijun Zhang, Qiong Zhang, Shaolian Zhou, Counde Oyang, Peter Atadja, En Li

Cancer Research Jul 2017, 77 (13 Supplement) LB-288; DOI: 10.1158/1538-7445.AM2017-LB-288
Abstract DDT01-02: AZD5991: A potent and selective macrocyclic inhibitor of Mcl-1 for treatment of hematologic cancers
Alexander W. Hird, J. Paul Secrist, Ammar Adam, Matthew A. Belmonte, Eric Gangl, Frank Gibbons, David Hargreaves, Jeffrey W. Johannes, Stephen L. Kazmirski, Jason G. Kettle, Stephen E. Kurtz, Michelle L. Lamb, Martin J. Packer, Bo Peng, Craig R. Stewart, Jeffrey W. Tyner, Wenzhan Yang, Qing Ye, XiaoLan Zheng, Edwin A. Clark

Cancer Research Jul 2017, 77 (13 Supplement) DDT01-02; DOI: 10.1158/1538-7445.AM2017-DDT01-02
Abstract LB-322: MicroRNA-130a suppresses breast cancer cell migration and invasion by targeting FOSL1 and upregulating ZO-1
Xiaowei Chen, Min Zhao, Yuhuang Li, Mushui Dai

Cancer Research Jul 2017, 77 (13 Supplement) LB-322; DOI: 10.1158/1538-7445.AM2017-LB-322
Abstract LB-272: KPNA7 nuclear import protein - a key regulator of cancer cell growth and nuclear morphology
Elisa M. Vuorinen, Nina Rajala, Teemu Ihalainen, Hanna E. Rauhala, Anssi Nurminen, Vesa P. Hytonen, Anne Kallioniemi

Cancer Research Jul 2017, 77 (13 Supplement) LB-272; DOI: 10.1158/1538-7445.AM2017-LB-272
Abstract LB-321: Cytoplasmic DEDD promotes G1- to S-phase cell cycle transition
Keon R. Schmidt, Yingjia Ni, Siyuan Zhang

Cancer Research Jul 2017, 77 (13 Supplement) LB-321; DOI: 10.1158/1538-7445.AM2017-LB-321
Abstract LB-274: Whole-exome sequencing reveals tyrosine kinase-resistant mutations in pretreatment EGFR-mutant lung adenocarcinomas
Xu-yuan Gao, Hang Xu, James CM Ho, Oscar SH Chan, Feng Xu, Junwen Wang, Victor HF Lee, Vicky PC Tin, Zhijie Xiao, Siqi Wang, Judy WP Yam, Maria P. Wong

Cancer Research Jul 2017, 77 (13 Supplement) LB-274; DOI: 10.1158/1538-7445.AM2017-LB-274
Abstract LB-315: Cyclin dependent kinase 7 represents a promising therapeutic target in glioma
Sameer A. Greenall, Terrance G. Johns

Cancer Research Jul 2017, 77 (13 Supplement) LB-315; DOI: 10.1158/1538-7445.AM2017-LB-315
Abstract LB-269: PFKP/PFKFB3 modulate metabolic switch and chemoresistance to cisplatin in ovarian cancer
Jingjing Wang, Michelle KY Siu, Yuxin Jiang, Thomas HY Leung, Hextan YS NGAN, Annie NY Cheung, Karen KL Chan

Cancer Research Jul 2017, 77 (13 Supplement) LB-269; DOI: 10.1158/1538-7445.AM2017-LB-269
Abstract DDT01-01: The discovery and preclinical characterization of AMG 176: A first-in-class Mcl-1 inhibitor in clinical development for multiple myeloma
Paul E. Hughes

Cancer Research Jul 2017, 77 (13 Supplement) DDT01-01; DOI: 10.1158/1538-7445.AM2017-DDT01-01

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