Basic Sciences:

Methotrexate Levels in the Interstitial Space and Seminiferous Tubule of Rat Testis

Riccardo Riccardi, Robert A. Vigersky, Susan Barnes, W. Archie Bleyer, and David G. Poplack
Cancer Res 1982 42: 1617-1619. [Abstract] [PDF]  

Selective Activation of Some Dihydrodiols of Several Polycyclic Aromatic Hydrocarbons to Mutagenic Products by Prostaglandin Synthetase

Janet Guthrie, Iain G. C. Robertson, Errol Zeiger, Jeffrey A. Boyd, and Thomas E. Eling
Cancer Res 1982 42: 1620-1623. [Abstract] [PDF]  

Antitumor Activity of the 3'-Chloroethylnitrosourea Analog of Thymidine and the Prevention by Co-administered Thymidine of Lethality but Not of Anticancer Activity

Tai-Shun Lin, Paul H. Fischer, John C. Marsh, and William H. Prusoff
Cancer Res 1982 42: 1624-1629. [Abstract] [PDF]  

Effect of Macrophages on Phorbol Ester-stimulated Comitogenesis in Bovine Lymphocytes

Andrea M. Mastro and Karen G. Pepin
Cancer Res 1982 42: 1630-1635. [Abstract] [PDF]  

Deceleratory Growth by a Rat Glial Tumor Line in Culture

Philip Skehan and Susan J. Friedman
Cancer Res 1982 42: 1636-1640. [Abstract] [PDF]  

Methotrexate Cytotoxicity for L5178Y/Asn^- Lymphoblasts: Relationship of Dose and Duration of Exposure to Tumor Cell Viability

D. A. Keefe, Robert L. Capizzi, and Seth A. Rudnick
Cancer Res 1982 42: 1641-1645. [Abstract] [PDF]  

Cell-mediated Mutagenicity in Chinese Hamster V79 Cells of Dibenzopyrenes and Their Bay-Region Fluorine-substituted Derivatives

Bruce S. Hass, Catherine K. McKeown, Dennis J. Sardella, Eliahu Boger, Pallab K. Ghoshal, and Eliezer Huberman
Cancer Res 1982 42: 1646-1649. [Abstract] [PDF]  

Monoclonal Antibodies Recognizing Tumor-associated Antigen of Human Ovarian Mucinous Cystadenocarcinomas

Malaya Bhattacharya, Sunil K. Chatterjee, Joseph J. Barlow, and Hiroshi Fuji
Cancer Res 1982 42: 1650-1654. [Abstract] [PDF]  

Establishment of Methotrexate-resistant Human Acute Lymphoblastic Leukemia Cells in Culture and Effects of Folate Antagonists

Taisuke Ohnoshi, Takao Ohnuma, Isao Takahashi, Kevin Scanlon, Barton A. Kamen, and James F. Holland
Cancer Res 1982 42: 1655-1660. [Abstract] [PDF]  

Implementation of Micromethods to Resolve Problems of Human Breast Tumor Heterogeneity in Analysis of Cyclic 3':5'-Nucleotide Phosphodiesterase

Elizabeth H. Larner and Charles L. Rutherford
Cancer Res 1982 42: 1661-1668. [Abstract] [PDF]  

Immune Selection of Tumor Cell Variants in Chickens Bearing Tumors Induced by Avian Sarcoma Virus

Mark A. Wainberg, Evelyne Israel, and Margaret Yu
Cancer Res 1982 42: 1669-1675. [Abstract] [PDF]  

Identification of Phorbol Ester Receptors in T-Cell Growth Factor-producing and -nonproducing EL4 Mouse Thymoma Cells

Julianne J. Sando, Mary L. Hilfiker, Mark J. Piacentini, and Terri M. Laufer
Cancer Res 1982 42: 1676-1680. [Abstract] [PDF]  

Benzo(a)pyrene Phenol Production by Perfused Rat Liver and Its Inhibition by Ethanol

Lester A. Reinke, Paul McManus, Frederick C. Kauffman, and Ronald G. Thurman
Cancer Res 1982 42: 1681-1685. [Abstract] [PDF]  

Receptor-dependent Antiproliferative Effects of Corticosteroids in Radiation-induced Fibrosarcomas and Implications for Sequential Therapy

Paul G. Braunschweiger, Han L. Ting, and Lewis M. Schiffer
Cancer Res 1982 42: 1686-1691. [Abstract] [PDF]  

Effect of L-Phenylalanine Mustard, Adriamycin, Actinomycin D, and 4'-(9-Acridinylamino)methanesulfon-m-anisidide on Naturally Occurring Human Spontaneous Monocyte-mediated Cytotoxicity

Eugenie S. Kleinerman, Leonard A. Zwelling, Ronald Schwartz, and Andrew V. Muchmore
Cancer Res 1982 42: 1692-1695. [Abstract] [PDF]  

Pharmacology and Toxicity of a Potent "Nonclassical" 2,4-Diamino Quinazoline Folate Antagonist, Trimetrexate, in Normal Dogs

Eleanor C. Weir, Arlene R. Cashmore, Robert N. Dreyer, Michael L. Graham, Nina Hsiao, Barbara A. Moroson, Wendy L. Sawicki, and Joseph R. Bertino
Cancer Res 1982 42: 1696-1702. [Abstract] [PDF]  

Components of Hematoporphyrin Derivatives and Their Tumor-localizing Capacity

David Kessel
Cancer Res 1982 42: 1703-1706. [Abstract] [PDF]  

Toxicity and Anticancer Activity of a New Triazine Antifolate (NSC 127755)

Thomas H. Corbett, Wilbur R. Leopold, Donald J. Dykes, Billy J. Roberts, Daniel P. Griswold, Jr., and Frank M. Schabel, Jr.
Cancer Res 1982 42: 1707-1715. [Abstract] [PDF]  

Correlation between Amounts of Cellular Membrane Components and Sensitivity to Hyperthermia in a Variety of Mammalian Cell Lines in Culture

Anne E. Cress, Patrick S. Culver, Thomas E. Moon, and Eugene W. Gerner
Cancer Res 1982 42: 1716-1721. [Abstract] [PDF]  

Effect of Microsomal Cytochrome P-450 Isozyme Induction on the Mutagenic Activation of 2-Aminoanthracene

Richard L. Norman, Ursula Muller-Eberhard, and Eric F. Johnson
Cancer Res 1982 42: 1722-1726. [Abstract] [PDF]  

Hormonal Regulation of Net DNA Synthesis in MCF-7 Human Breast Cancer Cells in Tissue Culture

Susan C. Aitken and Marc E. Lippman
Cancer Res 1982 42: 1727-1735. [Abstract] [PDF]  

Influence of Tetrahydrouridine on the Pharmacokinetics of Intrathecally Administered 1-ß-D-arabinofuranosylcytosine

Riccardo Riccardi, Bruce Chabner, Daniel L. Glaubiger, James Wood, and David G. Poplack
Cancer Res 1982 42: 1736-1739. [Abstract] [PDF]  

Effects of Partially Thiolated Polycytidylic Acid and Liposomes on in Vitro Colony-forming Cells of Leukemic Mice

Yau-Kwan Ho, Eric Mayhew, Harvey D. Preisler, and Thomas J. Bardos
Cancer Res 1982 42: 1740-1743. [Abstract] [PDF]  

Development of Thermotolerance during Fractionated Hyperthermia in a Solid Tumor in Vivo

Toshiharu Kamura, Ole S. Nielsen, Jens Overgaard, and Anders H. Andersen
Cancer Res 1982 42: 1744-1748. [Abstract] [PDF]  

Biochemical Properties of the High-Molecular-Weight Glycopeptides Released from the Cell Surface of Human Teratocarcinoma Cells

Hisako Muramatsu, Takashi Muramatsu, and Philip Avner
Cancer Res 1982 42: 1749-1752. [Abstract] [PDF]  

Detection of Ductal Dysplasia in Mammary Outgrowths Derived from Carcinogen-treated Virgin Female BALB/c Mice

Stephen P. Ethier and Robert L. Ullrich
Cancer Res 1982 42: 1753-1760. [Abstract] [PDF]  

Effect of Magnesium Content on Density-dependent Regulation of the Onset of DNA Synthesis in Transformed 3T3 Cells

H. Rubin
Cancer Res 1982 42: 1761-1768. [Abstract] [PDF]  

Effect of cis- and trans-Dichlorodiammineplatinum(II) on Human Tumor Cell Proliferation in Diffusion Chambers in Vivo

Kathleen R. Ambrose and Jon S. Lowrey
Cancer Res 1982 42: 1769-1773. [Abstract] [PDF]  

Inhibition of Methylazoxymethanol-induced Intestinal Tumors in the Rat by Pyrazole with Paradoxical Effects on Skin and Kidney

James Notman, Queng Hui Tan, and Morris S. Zedeck
Cancer Res 1982 42: 1774-1780. [Abstract] [PDF]  

Enhanced Effect of Gastrin on Rat Stomach Carcinogenesis Induced by N-Methyl-N'-nitro-N-nitrosoguanidine

Eiichi Tahara, Fumio Shimamoto, Kyohiko Taniyama, Hisao Ito, Yasutoshi Kosako, and Hiromichi Sumiyoshi
Cancer Res 1982 42: 1781-1787. [Abstract] [PDF]  

Characterization of Growth-inhibitory Activities Associated with an -Macroglobulin of Mice

Peter H. Koo
Cancer Res 1982 42: 1788-1797. [Abstract] [PDF]  

Monoclonal Antibodies That Inhibit Enzyme Activity of 3-Methylcholanthrene-induced Cytochrome P-450

Sang S. Park, Tadahiko Fujino, Donna West, F. Peter Guengerich, and Harry V. Gelboin
Cancer Res 1982 42: 1798-1808. [Abstract] [PDF]  

Correlation between the Rates of Aerobic Glycolysis and Glucose Transport, Unrelated to Neoplastic Transformation, in a Series of BALB 3T3-derived Cell Lines

Beverly Peterkofsky and Willie Prather
Cancer Res 1982 42: 1809-1816. [Abstract] [PDF]  

Doxorubicin-induced Chronic Cardiotoxicity and Its Protection by Liposomal Administration

Aquilur Rahman, Newton More, and Philip S. Schein
Cancer Res 1982 42: 1817-1825. [Abstract] [PDF]  

Transepithelial Invasion and Intramesenchymal Infiltration of the Chick Embryo Chorioallantois by Tumor Cell Lines

Peter B. Armstrong, James P. Quigley, and Eric Sidebottom
Cancer Res 1982 42: 1826-1837. [Abstract] [PDF]  

Homogeneously Staining Regions in Direct Preparations from Human Neuroblastomas

Gloria Balaban and Fred Gilbert
Cancer Res 1982 42: 1838-1842. [Abstract] [PDF]  

Conversion of Malignant Murine Embryonal Carcinomas to Benign Teratomas by Chemical Induction of Differentiation in Vivo

Wendell C. Speers
Cancer Res 1982 42: 1843-1849. [Abstract] [PDF]  

Inhibition of Cellular Division of a Murine Macrophage Tumor by Macrophage-activating Agents

James E. Talmadge, Patricia A. Donovan, and Ian R. Hart
Cancer Res 1982 42: 1850-1855. [Abstract] [PDF]  

Evidence for Single-Cell Origin of 3-Methylcholanthrene-induced Fibrosarcomas in Mice with Cellular Mosaicism

Hiroshi Tanooka and Kazuhiko Tanaka
Cancer Res 1982 42: 1856-1858. [Abstract] [PDF]  

Metabolism of Benzo(a)pyrene in Epidermal Keratinocytes and Dermal Fibroblasts of Humans and Mice with Reference to Variation among Species, Individuals, and Cell Types

Toshio Kuroki, Jiro Hosomi, Kimiyo Munakata, Takuya Onizuka, Masami Terauchi, and Nobuo Nemoto
Cancer Res 1982 42: 1859-1865. [Abstract] [PDF]  

Induction of Cytotoxicity, Mutation, Cytogenetic Changes, and Neoplastic Transformation by Benzo(a)pyrene and Derivatives in C3H/10T Clone 8 Mouse Fibroblasts

Eugene B. Gehly, Joseph R. Landolph, Charles Heidelberger, Hatsumi Nagasawa, and John B. Little
Cancer Res 1982 42: 1866-1875. [Abstract] [PDF]  

Inhibition of Mitochondrial Protein Synthesis during Early Stages of Aflatoxin B₁-induced Hepatocarcinogenesis

Narayan K. Bhat, John K. Emeh, Banavadi G. Niranjan, and Narayan G. Avadhan
Cancer Res 1982 42: 1876-1880. [Abstract] [PDF]  

Dome Formation by a Retrovirus-induced Lung Adenocarcinoma Cell Line

Angie Rizzino, Matthew A. Gonda, and Ulf R. Rapp
Cancer Res 1982 42: 1881-1887. [Abstract] [PDF]  

Protective Effects of S-2-(3-Aminopropylamino)ethylphosphorothioic Acid against Radiation Damage of Normal Tissues and a Fibrosarcoma in Mice

Luka Milas, Nancy Hunter, Betty O. Reid, and Howard D. Thames, Jr.
Cancer Res 1982 42: 1888-1897. [Abstract] [PDF]  

Arrest and Retention of Circulating Cancer Cells in the Lungs of Animals with Defined Metastatic Status

Leonard Weiss and Pamela M. Ward
Cancer Res 1982 42: 1898-1903. [Abstract] [PDF]  

Variants of an Interspecies Hybridoma with Altered Tumorigenicity and Protective Ability against Mouse Myeloma Tumors

R. Baumal, E. Musclow, H. Farkas-Himsley, and A. Marks
Cancer Res 1982 42: 1904-1908. [Abstract] [PDF]  

Induction of Sister Chromatid Exchange by Polyoma Large Viral Tumor Antigen in Transformed Rat Fibroblasts

Eric H. Brown and Claudio Basilico
Cancer Res 1982 42: 1909-1912. [Abstract] [PDF]  

Heterogeneity of Binding Sites for Tamoxifen and Tamoxifen Derivatives in Estrogen Target and Nontarget Fetal Organs of Guinea Pig

Alberto Gulino and Jorge Raul Pasqualini
Cancer Res 1982 42: 1913-1921. [Abstract] [PDF]  

Involvement of T-Lymphocytes in the Stimulatory Effects of EMT₆ Tumors on Medullary Pluripotent Stem Cells of BALB/c Mice

Marie-Pierre Fache, Françoise Lepault, and Emilia Frindel
Cancer Res 1982 42: 1922-1926. [Abstract] [PDF]  

Monoclonal Antibody against a Membrane Antigen Characterizing Leukemic Human B-Lymphocytes

Hansjörg K. Forster, Fred G. Gudat, Marie-F. Girard, Renate Albrecht, Jörg Schmidt, Christian Ludwig, and Jean-P. Obrecht
Cancer Res 1982 42: 1927-1934. [Abstract] [PDF]  

Partial Characterization and "Quantitation" of a Human Prostatic Estramustine-binding Protein

Per Björk, Björn Forsgren, Jan-Åke Gustafsson, Åke Pousette, and Bertil Högberg
Cancer Res 1982 42: 1935-1942. [Abstract] [PDF]  

Effect of X-Rays and Cyclophosphamide on Solid Tumors and Naturally Occurring Metastases in Mice

Ann M. Chu and Jack F. Fowler
Cancer Res 1982 42: 1943-1949. [Abstract] [PDF]  

Uptake, Efflux, and Hydrolysis of Aclacinomycin A in Friend Leukemia Cells

Alain Fourcade, Jean-Jacques Farhi, Myriam Bennoun, and Haim Tapiero
Cancer Res 1982 42: 1950-1954. [Abstract] [PDF]  

Copper- and Zinc-containing Superoxide Dismutase, Manganese-containing Superoxide Dismutase, Catalase, and Glutathione Peroxidase in Normal and Neoplastic Human Cell Lines and Normal Human Tissues

Stefan L. Marklund, N. Gunnar Westman, Erik Lundgren, and Göran Roos
Cancer Res 1982 42: 1955-1961. [Abstract] [PDF]  

Nondetection of O⁶-Methylguanine in Rat DNA following in Vivo Treatment with Large Doses of Cimetidine Alone or in Combination with Sodium Nitrite

Soterios A. Kyrtopoulos, Efstathios Hadjiloucas, and Birgitta Vrotsou
Cancer Res 1982 42: 1962-1966. [Abstract] [PDF]  

Estrone Receptor Formation During the Processing of Estradiol-Receptor Complex in MCF-7 Cells

E. R. Hansen and S. C. Brooks
Cancer Res 1982 42: 1967-1974. [Abstract] [PDF]  

Effects of Phorbol Esters on Basal Epidermal Cells Derived from Ear Skin of Adult Guinea Pigs

C. Delescluse, G. Fürstenberger, F. Marks, and M. Pruniéras
Cancer Res 1982 42: 1975-1979. [Abstract] [PDF]  

Tumor Promoter Stimulation of Phosphatidylcholine Turnover in HeLa Cells

Graeme R. Guy and Andrew W. Murray
Cancer Res 1982 42: 1980-1985. [Abstract] [PDF]  

Polysomal Polyadenylated RNA and Albumin Messenger RNA in Mastomys Liver and in a Chemically Induced Hepatocellular Carcinoma

Liselotte Krieg, Detlev Krause-Leipholdt, Klaus Wayss, and Manfred Volm
Cancer Res 1982 42: 1986-1993. [Abstract] [PDF]  

Loss of Melanogenic Properties in Tyrosinases Induced by Glycosylation Inhibitors within Malignant Melanoma Cells

Genji Imokawa and Yutaka Mishima
Cancer Res 1982 42: 1994-2002. [Abstract] [PDF]  

Vaginal Adenosis and Adenocarcinoma in Mice Exposed Prenatally or Neonatally to Diethylstilbestrol

Retha R. Newbold and John A. McLachlan
Cancer Res 1982 42: 2003-2011. [Abstract] [PDF]  

Immunochemical Differences among Carcinoembryonic Antigen in Tumor Tissues and Related Antigens in Meconium and Adult Feces

Yuji Matsuoka, Masahida Kuroki, Yoshiko Koga, Hiroshi Kuriyama, Takesada Mori, and Goro Kosaki
Cancer Res 1982 42: 2012-2018. [Abstract] [PDF]  

Biosynthesis of an Interstitial Type of Collagen by Cloned Human Gastric Carcinoma Cells

Kooko Sakakibara, Toshimitsu Suzuki, Teiichi Motoyama, Hidenobu Watanabe, and Yoshitaka Nagai
Cancer Res 1982 42: 2019-2027. [Abstract] [PDF]  

Monoclonal Antibodies in Analysis of Oncoplacental Protein SP₁ in Vivo and in Vitro

Eva Engvall, Masato Miyashita, and Erkki Ruoslahti
Cancer Res 1982 42: 2028-2033. [Abstract] [PDF]  

Histological, Proliferative, and Biochemical Alterations in Dorsal Epidermis of the Syrian Golden Hamster Induced by 12-O-Tetradecanoylphorbol-13-acetate and the Calcium Ionophore A 23187

Friedhelm Hasper, Gerhard Müller, and Jürgen Schweizer
Cancer Res 1982 42: 2034-2039. [Abstract] [PDF]  

Establishment and Characterization of SV40-transformed Human Breast Epithelial Cell Lines

Sidney E. Chang, Jacqueline Keen, E. Birgitte Lane, and Joyce Taylor-Papadimitriou
Cancer Res 1982 42: 2040-2053. [Abstract] [PDF]  

Clinical Investigations:

Diphtheria Toxin Treatment of Human Advanced Cancer

Silvio Buzzi
Cancer Res 1982 42: 2054-2058. [Abstract] [PDF]  

A Phase I Study of Intracarotid Artery Infusion of cis-Diamminedichloroplatinum(II) in Patients with Recurrent Malignant Intracerebral Tumors

David J. Stewart, Sidney Wallace, Lynn Feun, Milam Leavens, Sue Ellen Young, Stanley Handel, Giora Mavligit, and Robert S. Benjamin
Cancer Res 1982 42: 2059-2062. [Abstract] [PDF]  

Natural Killer Activity in Spleens and Lymph Nodes from Patients with Hodgkin's Disease

Luigi P. Ruco, Antonio Procopio, Stefania Uccini, Enrico Marcorelli, and Carlo D. Baroni
Cancer Res 1982 42: 2063-2068. [Abstract] [PDF]  

Pharmacology of 13-cis-Retinoic Acid in Humans

Ian G. Kerr, Marc E. Lippman, Jean Jenkins, and Charles E. Myers
Cancer Res 1982 42: 2069-2073. [Abstract] [PDF]  

Response to Luteinizing Releasing Hormone, Thyrotrophic Releasing Hormone, and Human Chorionic Gonadotrophin Administration in Health Men at Different Risks for Prostatic Cancer and in Prostatic Cancer Patients

P. Hill, E. L. Wynder, L. Garbaczewski, H. Garnes, and A. R. P. Walker
Cancer Res 1982 42: 2074-2080. [Abstract] [PDF]  

Optimal Scheduling of Methotrexate and 5-Fluorouracil in Human Breast Cancer

Chris Benz, Tina Tillis, Ellen Tattelman, and Ed Cadman
Cancer Res 1982 42: 2081-2086. [Abstract] [PDF]  

Pharmacokinetics of 13-cis-Retinoic Acid in Patients with Advanced Cancer

Gary E. Goodman, Janine G. Einspahr, David S. Alberts, Thomas P. Davis, Susan A. Leigh, H. S. George Chen, and Frank L. Meyskens
Cancer Res 1982 42: 2087-2091. [Abstract] [PDF]  

Modulation of 9-ß-D-Arabinofuranosyladenine 5'-Triphosphate and Deoxyadenosine Triphosphate in Leukemic Cells by 2'-Deoxycoformycin during Therapy with 9-ß-D-Arabinofuranosyladenine

William Plunkett, Robert S. Benjamin, Michael J. Keating, and Emil J Freireich
Cancer Res 1982 42: 2092-2096. [Abstract] [PDF]  

Letter to the Editor:

Urinary Excretion of Monoacetyl Polyamines in Patients with Non-Hodgkin's Lymphoma

Mahmoud M. Abdel-Monem, James L. Merdink, and Athanasios Theologides
Cancer Res 1982 42: 2097-2098. [Abstract] [PDF]  

Meeting Report:

Modified Nucleosides and Cancer

Ernest Borek
Cancer Res 1982 42: 2099-2100. [PDF]  

Articles:

Announcements

Cancer Res 1982 42: 2101 [PDF]  

Erratum:

Enhanced Inhibition of Mammary Carcinogenesis by Combined Treatment with N-(4-Hydroxyphenyl)retinamide and Ovariectomy.

Cancer Res 1982 42: 2102 [PDF]  

Effects of Tocopherol (Vitamin E) Acid Succinate on Morphological Alterations and Growth Inhibition in Melanoma Cells in Culture.

Cancer Res 1982 42: 2102 [PDF]  

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