Editorial:

Perspectives in Cancer Research

P. N. Magee
Cancer Res 1983 43: 3033 [PDF]  

Perspectives in Cancer Research:

Role of Retinoids in Differentiation and Carcinogenesis

Michael B. Spom and Anita B. Roberts
Cancer Res 1983 43: 3034-3040. [PDF]  

Basic Sciences:

Effect of Hyperglycemia on Thermochemotherapy of a Spontaneous Murine Fibrosarcoma

M. Urano and M. S. Kim
Cancer Res 1983 43: 3041-3044. [Abstract] [PDF]  

Inhibition of 7-Bromomethylbenz[a]anthracene-promoted Mouse Skin Tumor Formation by Retinoic Acid and Dexamethasone

Ajit K. Verma, C. T. Garcia, Curtis L. Ashendel, and R. K. Boutwell
Cancer Res 1983 43: 3045-3049. [Abstract] [PDF]  

Effect of Tumor Size on S-2-(3-Aminopropylamino)ethylphosphorothioic Acid and Misonidazole Alteration of Tumor Response to Cyclophosphamide

Luka Milas, Hisao Ito, and Nancy Hunter
Cancer Res 1983 43: 3050-3056. [Abstract] [PDF]  

Generation of Phenotypic Diversity in the B16 Mouse Melanoma Relative to Spontaneous Metastasis

Christopher W. Stackpole
Cancer Res 1983 43: 3057-3065. [Abstract] [PDF]  

Human NH₂ Terminal of Pro-opiomelanocortin as a Potential Marker for Pulmonary Carcinoma

John S. D. Chan, Nabil G. Seidah, and Michel Chrétien
Cancer Res 1983 43: 3066-3069. [Abstract] [PDF]  

Potentiation of DNA-reactive Antineoplastic Agents and Protection against S-Phase-specific Agents by Anguidine in Chinese Hamster Ovary Cells

Robert Hromas, Barthel Barlogie, Douglas Swartzendruber, and Benjamin Drewinko
Cancer Res 1983 43: 3070-3073. [Abstract] [PDF]  

Uptake, Initial Effects, and Chemotherapeutic Efficacy of Harringtonine in Murine Leukemic Cells Sensitive and Resistant to Vincristine and Other Chemotherapeutic Agents

Ting-Chao Chou, Franz A. Schmid, Aaron Feinberg, Frederick S. Philips, and Jui Han
Cancer Res 1983 43: 3074-3079. [Abstract] [PDF]  

Metabolism of Acrylonitrile by Isolated Rat Hepatocytes

Lee E. Geiger, Lora L. Hogy, and F. Peter Guengerich
Cancer Res 1983 43: 3080-3087. [Abstract] [PDF]  

Chemotherapy and Radiation Therapy of Human Medulloblastoma in Athymic Nude Mice

Henry S. Friedman, S. Clifford Schold, Jr., Mahesh Varia, and Darell D. Bigner
Cancer Res 1983 43: 3088-3093. [Abstract] [PDF]  

Characterization and Quantitation of Antiestrogen Binding Sites in Estrogen Receptor-positive and -negative Human Breast Cancer Cell Lines

Margaret Ann Miller and Benita S. Katzenellenbogen
Cancer Res 1983 43: 3094-3100. [Abstract] [PDF]  

Tumoricidal Effects of Sodium Hexachloroiridate on an Ascitic Tumor in Mice

Gerald M. Kolodny and Christopher Rose
Cancer Res 1983 43: 3101-3103. [Abstract] [PDF]  

Effect of 3-Aminobenzamide on the Rate of Ligation during Repair of Alkylated DNA in Human Fibroblasts

William F. Morgan and James E. Cleaver
Cancer Res 1983 43: 3104-3107. [Abstract] [PDF]  

Experimental Hyperthermic Isolation-Perfusion Using cis-Diamminedichloroplatinum(II)

Alan G. Wile, Maurice Y. Nahabedian, Donald A. Plumley, J. Edward Guilmette, and G. Robert Mason
Cancer Res 1983 43: 3108-3111. [Abstract] [PDF]  

Some Advantages of Curing Mice Bearing a Large Subcutaneous MOPC-315 Tumor with a Low Dose Rather Than a High Dose of Cyclophosphamide

Margalit B. Mokyr and Sheldon Dray
Cancer Res 1983 43: 3112-3119. [Abstract] [PDF]  

Role of the Acetylation Polymorphism in Determining Susceptibility of Cultured Rabbit Hepatocytes to DNA Damage by Aromatic Amines

Charlene A. McQueen, Carol J. Maslansky, and Gary M. Williams
Cancer Res 1983 43: 3120-3123. [Abstract] [PDF]  

Effect of Hyperthermia on the Survival of Normal Human Peripheral Blood Mononuclear Cells

Shyam S. Agarwal, Edward J. Katz, and Lawrence A. Loeb
Cancer Res 1983 43: 3124-3126. [Abstract] [PDF]  

Absence in Glucocorticoid-resistant Mouse Lymphoma P1798 of a Glucocorticoid Receptor Domain Responsible for Biological Effects

Sam Okret, Yee-Wan Stevens, Jan Carlstedt-Duke, Örjan Wrange, Jan-Åke Gustafsson, and John Stevens
Cancer Res 1983 43: 3127-3131. [Abstract] [PDF]  

Identification and Mutagenicity of Metabolites of 1-Nitropyrene Formed by Rat Liver

Karam El-Bayoumy and Stephen S. Hecht
Cancer Res 1983 43: 3132-3137. [Abstract] [PDF]  

Influence of Heat on the Intracellular Uptake and Radiosensitization of 2-Nitroimidazole Hypoxic Cell Sensitizers in Vitro

Dennis M. Brown, Mark S. Cohen, Robert H. Sagerman, Ricardo Gonzalez-Mendez, George M. Hahn, and J. Martin Brown
Cancer Res 1983 43: 3138-3142. [Abstract] [PDF]  

A Fast and Convenient Method for Determining Estrogen Receptor Using Rabbit Uterus as a Standard

J. Mukharji, N. Y. Zachariah, Z. H. Chakmakjian, and G. J. Race
Cancer Res 1983 43: 3143-3146. [Abstract] [PDF]  

Comparison of in Vitro Methods for Assessing Cytotoxic Activity against Two Pancreatic Adenocarcinoma Cell Lines

Barbara K. Chang
Cancer Res 1983 43: 3147-3149. [Abstract] [PDF]  

Nuclear Thyroid Hormone Receptors, -Glycerophosphate Dehydrogenases, and Malic Enzyme in N-Nitrosomethylurea-induced Rat Mammary Tumors

Frank J. Ruzicka and David P. Rose
Cancer Res 1983 43: 3150-3154. [Abstract] [PDF]  

Monoclonal Antibodies to Human Melanoma-associated Antigens: An Amplified Enzyme-linked Immunosorbent Assay for the Detection of Antigen, Antibody, and Immune Complexes

Alton C. Morgan, Jr. and Robert F. Mclntyre
Cancer Res 1983 43: 3155-3159. [Abstract] [PDF]  

Low Oral Bioavailability of Hexamethylmelamine in the Rat Due to Simultaneous Hepatic and Intestinal Metabolism

Pierre J. M. Klippert, Abram Hulshoff, Marie-José J. Mingels, Gerard Hofman, and Jan Noordhoek
Cancer Res 1983 43: 3160-3164. [Abstract] [PDF]  

Effects of Ultraviolet-visible Irradiation in the Presence of Melanin Isolated from Human Black or Red Hair upon Ehrlich Ascites Carcinoma Cells

I. Aravindakshan Menon, Surujdeen Persad, Narendranath S. Ranadive, and Herbert F. Haberman
Cancer Res 1983 43: 3165-3169. [Abstract] [PDF]  

Prolactin-like Activity of Antiprolactin Receptor Antibodies in Rat Mammary Tumor Explants

Marc Edery, Jean Djiane, Louis-Marie Houdebine, and Paul A. Kelly
Cancer Res 1983 43: 3170-3174. [Abstract] [PDF]  

Mechanism of Sensitization of Chinese Hamster Ovary Cells to Melphalan by Hypoxic Treatment with Misonidazole

Yvonne C. Taylor, James W. Evans, and J. Martin Brown
Cancer Res 1983 43: 3175-3181. [Abstract] [PDF]  

Use of Uridine Rescue to Enhance the Antitumor Selectivity of 5-Fluorouracil

Philip Klubes and Ingeborg Cerna
Cancer Res 1983 43: 3182-3186. [Abstract] [PDF]  

Systemic Lidocaine Enhancement of Hyperthermia-induced Tumor Regression in Transplantable Murine Tumor Models

H. Ian Robins, Warren H. Dennis, James S. Slattery, Thomas A. Lange, and Milton B. Yatvin
Cancer Res 1983 43: 3187-3191. [Abstract] [PDF]  

Combination Chemotherapy Involving -Difluoromethylornithine and 1-ß-D-Arabinofuranosylcytosine in Murine L1210 Leukemia

Nellikunja J. Prakash and Prasad S. Sunkara
Cancer Res 1983 43: 3192-3196. [Abstract] [PDF]  

Role of Lipid Transfer Proteins in the Abnormal Lipid Content of Morris Hepatoma Mitochondria and Microsomes

Richard C. Crain, Ronald W. Clark, and Brian E. Harvey
Cancer Res 1983 43: 3197-3202. [Abstract] [PDF]  

Modulation of Involucrin and Envelope Competence in Human Keratinocytes by Hydrocortisone, Retinyl Acetate, and Growth Arrest

Polly R. Cline and Robert H. Rice
Cancer Res 1983 43: 3203-3207. [Abstract] [PDF]  

Effects of Combination Estrogen:Cyclophosphamide Treatment on the Growth of the MXT Transplantable Mammary Tumor in the Mouse

B. M. Markaverich, D. Medina, and J. H. Clark
Cancer Res 1983 43: 3208-3211. [Abstract] [PDF]  

Involvement of both Syn- and Anti-Dihydrodiol-Epoxides in the Binding of 7,12-Dimethylbenz(a)anthracene to DNA in Mouse Embryo Cell Cultures

Josef T. Sawicki, Robert C. Moschel, and Anthony Dipple
Cancer Res 1983 43: 3212-3218. [Abstract] [PDF]  

Divergent Effects of Retinoids on Pancreatic and Liver Carcinogenesis in Azaserine-treated Rats

Daniel S. Longnecker, Elna T. Kuhlmann, and Thomas J. Curphey
Cancer Res 1983 43: 3219-3225. [Abstract] [PDF]  

Effects of Four Retinoids in N-Nitrosobis(2-oxopropyl)amine-treated Hamsters

Daniel S. Longnecker, Elna T. Kuhlmann, and Thomas J. Curphey
Cancer Res 1983 43: 3226-3230. [Abstract] [PDF]  

Interaction of Ultrasonic Hyperthermia with Two Alkylating Agents in a Murine Bladder Tumor

Frank W. Longo, Philip Tomashefsky, Bermard D. Rivin, and Myron Tannenbaum
Cancer Res 1983 43: 3231-3235. [Abstract] [PDF]  

Weak Promotion of C3H/10T Cell Transformation by Repeated Treatments with Formaldehyde

Janet H. Frazelle, Diane J. Abernethy, and Craig J. Boreiko
Cancer Res 1983 43: 3236-3239. [Abstract] [PDF]  

Thermal Survival Characteristics of Cell Subpopulations Isolated from a Heterogeneous Human Colon Tumor

John T. Leith, Philip Heyman, J. Keith DeWyngaert, Daniel L. Dexter, Paul Calabresi, and Arvin S. Glicksman
Cancer Res 1983 43: 3240-3246. [Abstract] [PDF]  

O⁶-Methylguanine-DNA Methyltransferase of Human Lymphoid Cells: Structural and Kinetic Properties and Absence in Repair-deficient Cells

Adrian L. Harris, Peter Karran, and Tomas Lindahl
Cancer Res 1983 43: 3247-3252. [Abstract] [PDF]  

Murine Metabolism and Disposition of Iron:Adriamycin Complexes

Merrill J. Egorin, Ronald E. Clawson, Louis A. Ross, Rosalind D. Friedman, Steven D. Reich, Avrom Pollak, and Nicholas R. Bachur
Cancer Res 1983 43: 3253-3262. [Abstract] [PDF]  

Loss of Tumorigenicity of Lewis Lung Carcinoma on the Chorioallantoic Membrane of the Chick Embryo

D. Belin and L. Ossowski
Cancer Res 1983 43: 3263-3269. [Abstract] [PDF]  

Direct and Indirect Clastogenic Activity of Anthracenedione in Chinese Hamster Ovary Cells

Larry J. Rosenberg and Walter N. Hittelman
Cancer Res 1983 43: 3270-3275. [Abstract] [PDF]  

Fluorescent Nitroheterocycles for Identifying Hypoxic Cells

Peggy L. Olive and Ralph E. Durand
Cancer Res 1983 43: 3276-3280. [Abstract] [PDF]  

Stimulation of Increased Capillary Endothelial Cell Motility by Chondrosarcoma Cell-derived Factors

J. Azizkhan, R. Sullivan, R. Azizkhan, B. R. Zetter, and M. Klagsbrun
Cancer Res 1983 43: 3281-3286. [Abstract] [PDF]  

Clonal Chromosome Changes in Stimulated Lymphocytes of Untreated Human B-Cell Leukemias

Naoki Sadamori, Tin Han, Jun Minowada, Sei-ichi Matsui, and Avery A. Sandberg
Cancer Res 1983 43: 3287-3291. [Abstract] [PDF]  

Organ-specific Promoting Effect of Phenobarbital and Saccharin in Induction of Thyroid, Liver, and Urinary Bladder Tumors in Rats after Initiation with N-Nitrosomethylurea

Hiroyuki Tsuda, Shoji Fukushima, Katsumi Imaida, Yasushi Kurata, and Nobuyuki Ito
Cancer Res 1983 43: 3292-3296. [Abstract] [PDF]  

Comparison of Soluble Protein Kinases from Normal Rat Prostates and Prostatic Dunning Tumors

Leland W. K. Chung and Karen Breitweiser
Cancer Res 1983 43: 3297-3304. [Abstract] [PDF]  

Immunocytochemical Demonstration of Hormonally Regulable Casein in Tumors Produced by a Rat Mammary Stem Cell Line

Philip S. Rudland, Christine M. Hughes, Anna C. Twiston Davies, and Michael J. Warburton
Cancer Res 1983 43: 3305-3309. [Abstract] [PDF]  

Nononcogenic Hormone-independent Alveoli Produced by Carcinogens in Cultured Mouse Mammary Glands

Frederick V. Schaefer, Quentin J. Tonelli, Michael S. Dickens, R. Philip Custer, and Sam Sorof
Cancer Res 1983 43: 3310-3315. [Abstract] [PDF]  

O⁶-Methylguanine Removal by Competent and Incompetent Human Lymphoblastoid Lines from the Same Male Individual

Robert M. Sklar and Bernard S. Strauss
Cancer Res 1983 43: 3316-3320. [Abstract] [PDF]  

Activation of Cyclic Adenosine 3':5'-Monophosphate-dependent Protein Kinase in H35 Hepatoma and Chinese Hamster Ovary Cells by a Phorbol Ester Tumor Promoter

Craig V. Byus, James M. Trevillyan, Leslie J. Cavit, and William H. Fletcher
Cancer Res 1983 43: 3321-3326. [Abstract] [PDF]  

Demonstration of Complex Antigenic Heterogeneity in a Human Glioma Cell Line and Eight Derived Clones by Specific Monoclonal Antibodies

Carol J. Wikstrand, Sandra H. Bigner, and Darell D. Bigner
Cancer Res 1983 43: 3327-3334. [Abstract] [PDF]  

Isolation and Characterization of Endoplasmic Reticulum and Golgi Apparatus from Hepatocyte Nodules in Male Wistar Rats

Lennart C. Eriksson, Ulla-Britta Torndal, and Göran N. Andersson
Cancer Res 1983 43: 3335-3347. [Abstract] [PDF]  

Alterations of Human Endometrial Stromal Cells Produced by N-Methyl-N'-nitro-N-nitrosoguanidine

B. Hugh Dorman, Jill M. Siegfried, and David G. Kaufman
Cancer Res 1983 43: 3348-3357. [Abstract] [PDF]  

Estimation of the Number of Genes Specifying the Heavy Chain of Mouse Thymus Leukemia Antigens

Ryszard Slomski, Christine L. Martens, and Edward P. Cohen
Cancer Res 1983 43: 3358-3361. [Abstract] [PDF]  

Regional Measurements of Blood Flow in Experimental RG-2 Rat Gliomas

Dennis R. Groothuis, Joseph F. Pasternak, Joan M. Fischer, Ronald G. Blasberg, Darell D. Bigner, and Nicholas A. Vick
Cancer Res 1983 43: 3362-3367. [Abstract] [PDF]  

Regional Measurements of Blood-to-Tissue Transport in Experimental RG-2 Rat Gliomas

Dennis R. Groothuis, Joan M. Fischer, Joseph F. Pasternak, Ronald G. Blasberg, Nicholas A. Vick, and Darell D. Bigner
Cancer Res 1983 43: 3368-3373. [Abstract] [PDF]  

Effect of Size on Portal Circulation of Hepatic Nodules from Carcinogen-treated Rats

James G. Conway, James A. Popp, Sungchul Ji, and Ronald G. Thurman
Cancer Res 1983 43: 3374-3378. [Abstract] [PDF]  

Characterization of a Differentiated Cat Melanoma Cell Line

Suraiya Rasheed
Cancer Res 1983 43: 3379-3384. [Abstract] [PDF]  

Calcium Modulation of Phorbol Ester-induced Alterations in Murine Macrophage Morphology

Bonita M. Smith, Robert J. Sturm, and Richard A. Carchman
Cancer Res 1983 43: 3385-3391. [Abstract] [PDF]  

Treatment of Mouse Mammary Tumors Using Combined Hyperthermia and Ischemia

Geraldine M. Baker and Eric A. Wright
Cancer Res 1983 43: 3392-3397. [Abstract] [PDF]  

Immunoprecipitation as a Tool for Studying Humoral Immunity of Natural and Experimental Hosts of Herpesvirus saimiri

Susanne Modrow, Helga Schmidt, and Hans Wolf
Cancer Res 1983 43: 3398-3402. [Abstract] [PDF]  

Clinical Investigations:

Multivariate Analysis of Prognostic Variables in Patients with Metastatic Testicular Cancer

George J. Bosl, Nancy L. Geller, Constance Cirrincione, Nicholas J. Vogelzang, B. J. Kennedy, Willet F. Whitmore, Jr., Davor Vugrin, Howard Scher, Jerome Nisselbaum, and Robert B. Golbery
Cancer Res 1983 43: 3403-3407. [Abstract] [PDF]  

Paradoxical Effects Associated with Supranormal Urinary Testosterone Excretion in Premenopausal Women with Breast Cancer: Increased Risk of Postmastectomy Recurrence and Higher Remission Rate after Ovariectomy

Giorgio Secreto and Barnett Zumoff
Cancer Res 1983 43: 3408-3411. [Abstract] [PDF]  

Pharmacokinetics of N⁴-Behenoyl-1-ß-D-arabinofuranosylcytosine in Patients with Acute Leukemia

Takanori Ueda, Toru Nakamura, Seisho Ando, Daizaburo Kagawa, Masataka Sasada, Haruto Uchino, Ikuo Johno, and Yuichi Akiyama
Cancer Res 1983 43: 3412-3416. [Abstract] [PDF]  

Plasma Pharmacokinetics of Adriamycin and Adriamycinol: Implications for the Design of in Vitro Experiments and Treatment Protocols

Raymond F. Greene, Jerry M. Collins, Jean F. Jenkins, James L. Speyer, and Charles E. Myers
Cancer Res 1983 43: 3417-3421. [Abstract] [PDF]  

Human Pharmacokinetics of a New Acridine Derivative, 4'-(9-Acridinylamino)methanesulfon-m-anisidide (NSC 249992)

Stephen W. Hall, Jacqueline Friedman, Sewa S. Legha, Robert S. Benjamin, Jordan U. Gutterman, and Ti Li Loo
Cancer Res 1983 43: 3422-3426. [Abstract] [PDF]  

Patterned Distribution of Metastases from Malignant Melanoma in Humans

S. M. de la Monte, G. William Moore, and Grover M. Hutchins
Cancer Res 1983 43: 3427-3433. [Abstract] [PDF]  

In Vivo Drug Sensitivity Assay of Clonogenic Human Melanoma Cells and Correlation with Treatment Outcome

John M. Kirkwood and John C. Marsh
Cancer Res 1983 43: 3434-3440. [Abstract] [PDF]  

Aberration of Poly(Adenosine Diphosphate-Ribose) Metabolism in Human Colon Adenomatous Polyps and Cancers

Kiyoshi Hirai, Kunihiro Ueda, and Osamu Hayaishi
Cancer Res 1983 43: 3441-3446. [Abstract] [PDF]  

Comparison of Electron Paramagnetic Resonance and Atomic Absorption Serum Copper Measurements in Human Normal Control and Cancer Patients

F. W. Kleinhans, Samuel C. Kline, William M. Dugan, Jr., and James G. Williams
Cancer Res 1983 43: 3447-3450. [Abstract] [PDF]  

S-Adenosylhomocysteine Catabolism and Basis for Acquired Resistance during Treatment of T-Cell Acute Lymphoblastic Leukemia with 2'-Deoxycoformycin Alone and in Combination with 9-ß-D-Arabinofuranosyladenine

Michael S. Hershfield, Nicholas M. Kredich, Charles A. Koller, Beverly S. Mitchell, Joanne Kurtzberg, Thomas R. Kinney, and John M. Falletta
Cancer Res 1983 43: 3451-3458. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1983 43: 3459-3460. [PDF]  

Books Received

Cancer Res 1983 43: 3462 [PDF]  

Books Received

Cancer Res 1983 43: 3462 [PDF]  

New Journal

Cancer Res 1983 43: 3462 [PDF]  

Errata:

Drug and Hormone Sensitivity of Estrogen Receptor-positive and -negative Human Breast Cancer Cells in Vitro

Cancer Res 1983 43: 3460 [PDF]  

Reliable Stereological Method for Estimating the Number of Microscopic Hepatocellular Foci from Their Transections

Cancer Res 1983 43: 3460 [PDF]  

Circulating Levels of Feline Leukemia and Sarcoma Viruses and Fibrosarcoma Regression in Persistently Viremic Cats

Cancer Res 1983 43: 3460 [PDF]  

Toxicity of Aziridinylbenzoquinone for Aerobic and Hypoxic Cells of a Transplanted Mouse Mammary Tumor and Interaction of the Drug with Radiation and Adriamycin

Cancer Res 1983 43: 3460 [PDF]  

Obituary:

Solomon Spiegelman: 1914–1983

Richard Axel
Cancer Res 1983 43: 3461 [PDF]  

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