Special Lecture:

The Biological Role of Oncogenes—Insights from Platelet-derived Growth Factor: Rhoads Memorial Award Lecture

Charles D. Stiles
Cancer Res 1985 45: 5215-5218. [Abstract] [PDF]  

Basic Sciences:

Activation of N-Nitrosobis(2-oxopropyl)amine and N-Nitroso(2-hydroxypropyl)-(2-oxopropyl)amine to Mutagens for V79 Cells by Isolated Hamster and Rat Pancreatic Acinar Cells

Mario M. Mangino, Dante G. Scarpelli, and Paul F. Hollenberg
Cancer Res 1985 45: 5219-5224. [Abstract] [PDF]  

Rat Lung Macrophage Tumor Cytotoxin Production: Impairment by Chronic in Vivo Cigarette Smoke Exposure

David A. Flick, Ricardo J. Gonzalez-Rothi, J. Ocie Harris, and George E. Gifford
Cancer Res 1985 45: 5225-5229. [Abstract] [PDF]  

Increased Sensitivity to Oxanosine, a Novel Nucleoside Antibiotic, of Rat Kidney Cells upon Expression of the Integrated Viral src Gene

Yoshimasa Uehara, Masami Hasegawa, Makoto Hori, and Hamao Umezawa
Cancer Res 1985 45: 5230-5234. [Abstract] [PDF]  

Long-Term Effect of 2-Hydroxyethyl Retinamide on Urinary Bladder Carcinogenesis and Tumor Transplantation in Fischer 344 Rats

Ricardo V. Quander, Steven L. Leary, John D. Strandberg, Barbara A. Yarbrough, and Robert A. Squire
Cancer Res 1985 45: 5235-5239. [Abstract] [PDF]  

Comparison of Intravenous versus Intracarotid Therapy with 1,3-Bis(2-chloroethyl)-1-nitrosourea in a Rat Brain Tumor Model

Dennis E. Bullard, Sandra H. Bigner, and Darell D. Bigner
Cancer Res 1985 45: 5240-5245. [Abstract] [PDF]  

Diversity of Adhesion to Basement Membrane Components of Human Pancreatic Adenocarcinomas

Christine L. Haberem and Herbert Z. Kupchik
Cancer Res 1985 45: 5246-5251. [Abstract] [PDF]  

Carcinogen-induced Lesions in the Rat Pancreas: Effects of Varying Levels of Essential Fatty Acid

B. D. Roebuck, Daniel S. Longnecker, Karen J. Baumgartner, and C. Dennis Thron
Cancer Res 1985 45: 5252-5256. [Abstract] [PDF]  

Modulation of Cytotoxicity of Menadione Sodium Bisulfite versus Leukemia L1210 by the Acid-soluble Thiol Pool

Steven A. Akman, Marian Dietrich, Rowan Chlebowski, Phyllis Limberg, and Jerome B. Block
Cancer Res 1985 45: 5257-5262. [Abstract] [PDF]  

Kinetics of Protein Synthesis Inactivation in Human T-Lymphocytes by Selective Monoclonal Antibody-Ricin Conjugates

John E. Leonard, Quing-cheng Wang, Nathan O. Kaplan, and Ivor Royston
Cancer Res 1985 45: 5263-5269. [Abstract] [PDF]  

Use of 5-Trifluoromethyldeoxycytidine and Tetrahydrouridine to Circumvent Catabolism and Exploit High Levels of Cytidine Deaminase in Tumors to Achieve DNA- and Target-directed Therapies

John A. Mekras, David A. Boothman, and Sheldon B. Greer
Cancer Res 1985 45: 5270-5280. [Abstract] [PDF]  

Effects of BMY 25282, a Mitomycin C Analogue, in Mitomycin C-resistant Human Colon Cancer Cells

James K. V. Willson, Byron H. Long, Subhas Chakrabarty, Diane E. Brattain, and Michael G. Brattain
Cancer Res 1985 45: 5281-5286. [Abstract] [PDF]  

Accumulation of 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone in Alkaloid Genotypes of Burley Tobacco during Postharvest Processing: Comparisons with N'-Nitrosonornicotine and Probable Nitrosamine Precursors

Roger A. Andersen and Thomas R. Kemp
Cancer Res 1985 45: 5287-5293. [Abstract] [PDF]  

Induction of Thymidine Kinase Activity in a Spontaneously Enzyme-deficient Murine Tumor Cell Line by Exposure in Vivo to the DNA-hypomethylating Agent 5-Aza-2'-deoxycytidine: Implications for Mechanisms of Tumor Progression

Robert G. Liteplo, Edi Alvarez, Philip Frost, and Robert S. Kerbel
Cancer Res 1985 45: 5294-5298. [Abstract] [PDF]  

Monoclonal Antibodies to the L1210 Murine Leukemia Cell Line and to a Drug-altered Subline

Carla Testorelli, Yvonne Laura Archetti, Paola Aresca, and Lorenza Del Vecchio
Cancer Res 1985 45: 5299-5303. [Abstract] [PDF]  

Isolation and Characterization of Chinese Hamster Ovary Cell Lines Sensitive to Mitomycin C and Bleomycin

Craig N. Robson, Adrian L. Harris, and Ian D. Hickson
Cancer Res 1985 45: 5304-5309. [Abstract] [PDF]  

Major Role of Hepatic Sulfotransferase Activity in the Metabolic Activation, DNA Adduct Formation, and Carcinogenicity of 1'-Hydroxy-2',3'-dehydroestragole in Infant Male C57BL/6J x C3H/HeJ F₁ Mice

Timothy R. Fennell, Roger W. Wiseman, James A. Miller, and Elizabeth C. Miller
Cancer Res 1985 45: 5310-5320. [Abstract] [PDF]  

Differential Sensitivity of a Mouse Myeloid Leukemia Cell Line and Normal Mouse Bone Marrow Cells to X-Ray-induced Chromosome Aberrations

Marilyn J. Aardema, William W. Au, Russell E. Hand, Jr., and R. Julian Preston
Cancer Res 1985 45: 5321-5327. [Abstract] [PDF]  

Uptake of Hematoporphyrin Derivative by Normal and Malignant Cells: Effect of Serum, pH, Temperature, and Cell Size

Ralph M. Böhmer and George Morstyn
Cancer Res 1985 45: 5328-5334. [Abstract] [PDF]  

Decrease of Metastatogenic Potential by Pregraft Treatment of Lewis Lung Carcinoma Cells with Proteinase and Protein Kinase Affinity Labels

Kurt-Wilhelm Stahl, Georges Mathé, and Gyula Kovacs
Cancer Res 1985 45: 5335-5340. [Abstract] [PDF]  

Increase in H-2 Antigen Expression and Immunogenicity of BL6 Melanoma Cells Treated with N-Methyl-N'-nitronitrosoguanidine

Elieser Gorelik, Samuele Peppoloni, Roy Overton, and Ronald B. Herberman
Cancer Res 1985 45: 5341-5347. [Abstract] [PDF]  

Synergistic Anticellular Effect of a Combination of ß-Interferon and Retinoic Acid against U937 Cells

Chi-Kuan Ho
Cancer Res 1985 45: 5348-5351. [Abstract] [PDF]  

Metabolism and Disposition of Menogaril (NSC 269148) in the Rabbit

Pierre Dodion, Merrill J. Egorin, Kathrin L. Engisch, and Nicholas R. Bachur
Cancer Res 1985 45: 5352-5357. [Abstract] [PDF]  

Activation of the Parathyroid Hormone Receptor-Adenylate Cyclase System in Osteosarcoma Cells by a Human Renal Carcinoma Factor

Robert A. Nissenson, Gordon J. Strewler, Richard D. Williams, and Steven C. Leung
Cancer Res 1985 45: 5358-5363. [Abstract] [PDF]  

Tissue-specific Enhancement of Uridine Utilization and 5-Fluorouracil Therapy in Mice by Benzylacyclouridine

James W. Damowski and Robert E. Handschumacher
Cancer Res 1985 45: 5364-5368. [Abstract] [PDF]  

Cytotoxicity of Human ß-Interferon for Differentiating Leukemic HL-60 Cells

A. W. Hamburger, C. P. White, R. E. Siebenlist, J. J. Sedmak, and S. E. Grossberg
Cancer Res 1985 45: 5369-5373. [Abstract] [PDF]  

Therapeutic Effect Reflected by Plasma Levels of a Viral Protein during Combination Chemotherapeutic Treatment of Mammary Tumor-bearing Mice

Earl M. Ritzi, Dan S. Martin, Robert L. Stolfi, and Sol Spiegelman
Cancer Res 1985 45: 5374-5378. [Abstract] [PDF]  

Protective Effect of S-2-(3-Aminopropylamino)ethylphosphorothioic Acid against Induction of Altered Hepatocyte Foci in Rats Treated Once with -Radiation within One Day after Birth

D. J. Grdina, C. Peraino, B. A. Cames, and C. K. Hill
Cancer Res 1985 45: 5379-5381. [Abstract] [PDF]  

Chemical Characterization of the Degradation Products of Vinblastine Dihydrogen Sulfate

Kuntebommanahalli N. Thimmaiah and V. Sagar Sethi
Cancer Res 1985 45: 5382-5385. [Abstract] [PDF]  

Structural Studies on the Degradation Products of Vincristine Dihydrogen Sulfate

V. Sagar Sethi and Kuntebommanahalli N. Thimmaiah
Cancer Res 1985 45: 5386-5389. [Abstract] [PDF]  

Manipulation of Experimental Rat and Rabbit Liver Tumor Blood Flow with Angiotensin II

Mark A. Burton, Bruce N. Gray, Gregory W. Self, John C. Heggie, and Phillip S. Townsend
Cancer Res 1985 45: 5390-5393. [Abstract] [PDF]  

Induction of DNA-DNA Cross-Link Formation in Human Cells by Various Psoralen Derivatives

Dieter C. Gruenert, Michael Ashwood-Smith, Reginald H. Mitchell, and James E. Cleaver
Cancer Res 1985 45: 5394-5398. [Abstract] [PDF]  

Repair of Psoralen-induced Cross-Links and Monoadducts in Normal and Repair-deficient Human Fibroblasts

Dieter C. Gruenert and James E. Cleaver
Cancer Res 1985 45: 5399-5404. [Abstract] [PDF]  

Enzymes of Uracil Catabolism in Normal and Neoplastic Human Tissues

Fardos N. M. Naguib, Mahmoud H. el Kouni, and Sungman Cha
Cancer Res 1985 45: 5405-5412. [Abstract] [PDF]  

Differential Expression of Transforming Growth Factor- during Prenatal Development of the Mouse

Daniel R. Twardzik
Cancer Res 1985 45: 5413-5416. [Abstract] [PDF]  

Photoaffinity Labeling of the Progesterone Receptor from Human Endometrial Carcinoma

C. L. Clarke and P. G. Satyaswaroop
Cancer Res 1985 45: 5417-5420. [Abstract] [PDF]  

Identification of Mutagenic Metabolites of Indeno[1,2,3-cd]pyrene Formed in Vitro with Rat Liver Enzymes

Joseph E. Rice, Daniel T. Coleman, Thomas J. Hosted, Jr., Edmond J. LaVoie, Dan J. McCaustland, and James C. Wiley, Jr.
Cancer Res 1985 45: 5421-5425. [Abstract] [PDF]  

Inhibition of Tumor Promotion in Mouse Skin by 1,25-Dihydroxyvitamin D₃

Kazuhiro Chida, Hiroki Hashiba, Masafumi Fukushima, Tatsuo Suda, and Toshio Kuroki
Cancer Res 1985 45: 5426-5430. [Abstract] [PDF]  

Effect of Pretreatment with Cyclophosphamide on High-Dose Toxicity of Melphalan in Mice

Sulabha S. Kulkami, George S. Leventon, Lap Huynh, Herbert Chow, Karel A. Dicke, and Axel R. Zander
Cancer Res 1985 45: 5431-5435. [Abstract] [PDF]  

Development of Enzyme Immunoassay for Chromomycin A₃ and Olivomycin Using ß-D-Galactosidase as a Label

Kunio Fujiwara, Hideki Nakamura, and Tsunehiro Kitagawa
Cancer Res 1985 45: 5442-5446. [Abstract] [PDF]  

Mixed Function Oxidase Activities of Established Human Colon Carcinoma Cell Lines in the Activation of Cyclophosphamide

P. S. Moskwa, H. Vadi, and B. Drewinko
Cancer Res 1985 45: 5447-5451. [Abstract] [PDF]  

Comparison of Heat and/or Radiation Sensitivity and Membrane Composition of Seven X-Ray-transformed C3H 10T Cell Lines and Normal C3H 10T Cells

G. P. Raaphorst, J. A. Vadasz, E. I. Azzam, M. D. Sargent, J. Borsa, and M. Einspenner
Cancer Res 1985 45: 5452-5456. [Abstract] [PDF]  

Inhibition of N-Nitrosodimethylamine Metabolism in Rats by Ether Anesthesia

Larry K. Keefer, William A. Garland, Neil F. Oldfield, James E. Swagzdis, and Bruce A. Mico
Cancer Res 1985 45: 5457-5460. [Abstract] [PDF]  

Correlation of Sister Chromatid Exchange Frequency with Mutation Induction and Cell Survival in Chinese Hamster Ovary Cells Exposed to N-Oxidized Arylamines

Suzanne M. Morris, Robert H. Heflich, and Ralph L. Kodell
Cancer Res 1985 45: 5461-5465. [Abstract] [PDF]  

Topical Chemotherapy of Intradermal Walker 256 Carcinosarcoma with Diaziquone and Doxorubicin in the Rat

David J. Moore, Garth Powis, Ronald L. Richardson, and Mark R. Pittelkow
Cancer Res 1985 45: 5466-5472. [Abstract] [PDF]  

Splenic Immune Effector and Suppressor Cells in Mice Bearing a Growing Plasmacytoma

Yi-Hsiang Chen, Alan B. Anderson, and Karen G. Williams
Cancer Res 1985 45: 5473-5479. [Abstract] [PDF]  

Differential Cellular Retention of Vincristine and Vinblastine by Cultured Human Promyelocytic Leukemia HL-60/Cl Cells: The Basis of Differential Toxicity

Peter J. Ferguson and Carol E. Cass
Cancer Res 1985 45: 5480-5488. [Abstract] [PDF]  

Effects of Dietary Selenium Concentration on the Development of Enzyme-altered Liver Foci and Hepatocellular Carcinoma Induced by Diethylnitrosamine or N-Acetylaminofluorene in Rats

Robert A. LeBoeuf, Brian A. Laishes, and William G. Hoekstra
Cancer Res 1985 45: 5489-5495. [Abstract] [PDF]  

Effects of Selenium on Cell Proliferation in Rat Liver and Mammalian Cells as Indicated by Cytokinetic and Biochemical Analysis

Robert A. LeBoeuf, Brian A. Laishes, and William G. Hoekstra
Cancer Res 1985 45: 5496-5504. [Abstract] [PDF]  

Cell Surface Glycopeptides from Human Intestinal Epithelial Cell Lines Derived from Normal Colon and Colon Adenocarcinomas

Adel Youakim and Annette Herscovics
Cancer Res 1985 45: 5505-5511. [Abstract] [PDF]  

Biochemical Differences among Four Inosinate Dehydrogenase Inhibitors, Mycophenolic Acid, Ribavirin, Tiazofurin, and Selenazofurin, Studied in Mouse Lymphoma Cell Culture

Huey-Jane Lee, Katarzyna Pawlak, Binh T. Nguyen, Roland K. Robins, and Wolfgang Sadée
Cancer Res 1985 45: 5512-5520. [Abstract] [PDF]  

Tumor Cell Generation of Thrombin via Functional Prothrombinase Assembly

Livingston VanDeWater, Paula B. Tracy, Denise Aronson, Kenneth G. Mann, and Harold F. Dvorak
Cancer Res 1985 45: 5521-5525. [Abstract] [PDF]  

Use of a Highly Sensitive Assay to Analyze the Excision Repair of Dimer and Nondimer DNA Damages Induced in Human Skin Fibroblasts by 254-nm and Solar Ultraviolet Radiation

Barry S. Rosenstein, Joseph T. Murphy, and Jonathan M. Ducore
Cancer Res 1985 45: 5526-5531. [Abstract] [PDF]  

Anthrapyrazoles, a New Class of Intercalating Agents with High-Level, Broad Spectrum Activity against Murine Tumors

Wilbur R. Leopold, James M. Nelson, Jacqueline Plowman, and Robert C. Jackson
Cancer Res 1985 45: 5532-5539. [Abstract] [PDF]  

Heterogeneity of [³H]Phorbol 12,13-Dibutyrate Binding in Primary Mouse Keratinocytes at Different Stages of Maturation

Joseph A. Dunn, Arco Y. Jeng, Stuart H. Yuspa, and Peter M. Blumberg
Cancer Res 1985 45: 5540-5546. [Abstract] [PDF]  

Parabiotic Transfer of Cancer Anorexia/Cachexia in Male Rats

Jeffrey A. Norton, Jeffrey F. Moley, Michael V. Green, Richard E. Carson, and Seoras D. Morrison
Cancer Res 1985 45: 5547-5552. [Abstract] [PDF]  

Effects of Uridine and Thymidine on the Degradation of 5-Fluorouracil, Uracil, and Thymine by Rat Liver Dihydropyrimidine Dehydrogenase

Mendel Tuchman, Margaret L. R. Ramnaraine, and Robert F. O'Dea
Cancer Res 1985 45: 5553-5556. [Abstract] [PDF]  

In Vitro Effects of N,N-Dimethylformamide on Sublethal and Potentially Lethal Damage Recovery Processes after X-Irradiation in Heterogeneous Human Colon Tumor Cells

Carla M. Arundel, Arvin S. Glicksman, and John T. Leith
Cancer Res 1985 45: 5557-5562. [Abstract] [PDF]  

Activity of a Novel 4-Quinolinecarboxylic Acid, NSC 368390 [6-Fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarboxylic Acid Sodium Salt], against Experimental Tumors

Daniel L. Dexter, David P. Hesson, Robert J. Ardecky, Ganti V. Rao, Davette L. Tippett, Betsy A. Dusak, Kenneth D. Paull, Jacqueline Plowman, Barbara M. DeLarco, V. L. Narayanan, and Martin Forbes
Cancer Res 1985 45: 5563-5568. [Abstract] [PDF]  

Enzyme Specificity in the Metabolic Activation of N-Nitrosodimethylamine to a Mutagen for Chinese Hamster V79 Cells

Jeong-Sook H. Yoo and Chung S. Yang
Cancer Res 1985 45: 5569-5574. [Abstract] [PDF]  

Basic Seciences:

Development of a Miniaturized, Improved Nucleic Acid Precursor Incorporation Assay for Chemosensitivity Testing of Human Solid Tumors

David H. Kern, Carol R. Drogemuller, Michael C. Kennedy, Susanne U. Hildebrand-Zanki, Nobuhiko Tanigawa, and Vernon K. Sondak
Cancer Res 1985 45: 5436-5441. [Abstract] [PDF]  

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