Basic Sciences:

Use of High-Resolution ³¹P-labeled Topical Magnetic Resonance Spectroscopy to Monitor in Vivo Tumor Metabolism in Rats

M. G. Irving, S. J. Simpson, J. Field, and D. M. Doddrell
Cancer Res 1985 45: 481-486. [Abstract] [PDF]  

Restoration of T-Cell Function and Induction of Antitumor Immune Response in T-Cell-depressed Spontaneously Hypertensive Rats by Treatment with Thymosin Fraction 5

Noritoshi Takeichi, Yutaka Koga, Takashi Fujii, and Hiroshi Kobayashi
Cancer Res 1985 45: 487-491. [Abstract] [PDF]  

Role of Ligand Exchange Processes in the Reaction Kinetics of the Antitumor Drug cis-Diamminedichloroplatinum(II) with Its Targets

Evelyne Segal and Jean-Bernard Le Pecq
Cancer Res 1985 45: 492-498. [Abstract] [PDF]  

Elimination of Malignant Clonogenic Cells from Human Bone Marrow Using Multiple Monoclonal Antibodies and Complement

R. C. Bast, Jr., P. De Fabritiis, J. Lipton, R. Gelber, C. Maver, L. Nadler, S. Sallan, and J. Ritz
Cancer Res 1985 45: 499-503. [Abstract] [PDF]  

Decreased Intracellular Glutathione Concentration and Increased Hyperthermic Cytotoxicity in an Acid Environment

Michael L. Freeman, Arnold W. Malcolm, and Michael J. Meredith
Cancer Res 1985 45: 504-508. [Abstract] [PDF]  

Modification of Uptake and Antiproliferative Effect of Methylglyoxal Bis(guanylhydrazone) by Treatment with -Difluoromethylornithine in Rodent Cell Lines with Different Sensitivities to Methylglyoxal Bis(guanylhydrazone)

Leena Alhonen-Hongisto, Victor A. Levin, and Laurence J. Marton
Cancer Res 1985 45: 509-514. [Abstract] [PDF]  

Use of a New Citrulline Incorporation Assay to Investigate Inhibition of Intercellular Communication by 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)-ethane in Human Fibroblasts

James S. Davidson, Ingrid Baumgarten, and Eric H. Harley
Cancer Res 1985 45: 515-519. [Abstract] [PDF]  

Adducts from in Vivo Action of the Carcinogen 4-Hydroxyaminoquinoline 1-Oxide in Rats and from in Vitro Reaction of 4-Acetoxyaminoquinoline 1-Oxide with DNA and Polynucleotides

Sylvie Galiègue-Zouitina, Bernard Bailleul, and Marie-H. Loucheux-Lefebvre
Cancer Res 1985 45: 520-525. [Abstract] [PDF]  

Eradication of a Disseminated Syngeneic Mouse Lymphoma by Systemic Adoptive Transfer of Immune Lymphocytes and Its Dependence upon a Host Component(s)

James J. Mulé, Maury Rosenstein, Suyu Shu, and Steven A. Rosenberg
Cancer Res 1985 45: 526-531. [Abstract] [PDF]  

Mechanism of Antitumor Action of Pyrimidinones in the Treatment of B16 Melanoma and P388 Leukemia

Li H. Li, Tanya L. Wallace, Karen A. Richard, and Daniel E. Tracey
Cancer Res 1985 45: 532-538. [Abstract] [PDF]  

Hormonal Therapy of Human Endometrial Adenocarcinoma in a Nude Mouse Model

Richard J. Zaino, Pondichery G. Satyaswaroop, and Rodrigue Mortel
Cancer Res 1985 45: 539-541. [Abstract] [PDF]  

Carcinogenic Effect of Nitrosoalkylureas and Nitrosoalkylcarbamates in Syrian Hamsters

W. Lijinsky, G. L. Knutsen, and R. M. Kovatch
Cancer Res 1985 45: 542-545. [Abstract] [PDF]  

Tissue-specific Induction Patterns of Cancer-protective Enzymes in Mice by tert-Butyl-4-hydroxyanisole and Related Substituted Phenols

Mary J. De Long, Hans J. Prochaska, and Paul Talalay
Cancer Res 1985 45: 546-551. [Abstract] [PDF]  

Flow Cytometric Analysis of Pentakis(aziridino)thiatriazadiphosphorine Oxide (SOAz)-induced Changes in Cell Cycle Progression of HeLa and HL-60 Cells

Christiane Hecquet, Joëlle Nafziger, Xavier Ronot, Jean-Pierre Marie, and Monique Adolphe
Cancer Res 1985 45: 552-554. [Abstract] [PDF]  

Effect of Cyclophosphamide on Friend Virus Leukemogenesis in Virussensitive and Virus-resistant Mice

Radmila B. Raikow, James P. OKunewick, Mary J. Buffo, and Deborah L. Kociban
Cancer Res 1985 45: 555-557. [Abstract] [PDF]  

Effects of Dietary Fats and Butylated Hydroxytoluene on Mutagen Activation in Rats

Debra L. Ponder and Nancy R. Green
Cancer Res 1985 45: 558-560. [Abstract] [PDF]  

Inhibition of Human Malignant Neuroblastoma Cell DNA Synthesis by Lipoxygenase Metabolites of Arachidonic Acid

Eric J. Werner, Ronald W. Walenga, Ronald L. Dubowy, Sherry Boone, and Marie J. Stuart
Cancer Res 1985 45: 561-563. [Abstract] [PDF]  

A Common Biochemical Pattern in Preneoplastic Hepatocyte Nodules Generated in Four Different Models in the Rat

M. W. Roomi, R. K. Ho, D. S. R. Sarma, and E. Farber
Cancer Res 1985 45: 564-571. [Abstract] [PDF]  

Tumor Destruction and Kinetics of Tumor Cell Death in Two Experimental Mouse Tumors following Photodynamic Therapy

Barbara W. Henderson, Stephen M. Waldow, Thomas S. Mang, William R. Potter, Patrick B. Malone, and Thomas J. Dougherty
Cancer Res 1985 45: 572-576. [Abstract] [PDF]  

ß- to -Hydroxylation of the Esophageal Carcinogen Methyl-n-amylnitrosamine by the Rat Esophagus and Related Tissues

Sidney S. Mirvish, Ming-Yao Wang, James W. Smith, Ashok D. Deshpande, Moheb H. Makary, and Phillip Issenberg
Cancer Res 1985 45: 577-583. [Abstract] [PDF]  

Effect of Estrogens and Antiestrogens on Growth of Human Breast Cancer Cells in Athymic Nude Mice

C. Kent Osborne, Kim Hobbs, and Gary M. Clark
Cancer Res 1985 45: 584-590. [Abstract] [PDF]  

Covalent Binding of 7,12-Dimethylbenz(a)anthracene and 10-Fluoro-7,12-dimethylbenz(a)anthracene to Mouse Epidermal DNA and Its Relationship to Tumor-initiating Activity

J. DiGiovanni, E. P. Fisher, K. K. Aalfs, and W. P. Prichett
Cancer Res 1985 45: 591-597. [Abstract] [PDF]  

Activity of the New Antifolate N¹⁰-Propargyl-5,8-dideazafolate and Its Polyglutamates against Human Dihydrofolate Reductase, Human Thymidylate Synthetase, and KB Cells Containing Different Levels of Dihydrofolate Reductase

Y-C. Cheng, G. E. Dutschman, M. C. Starnes, M. H. Fisher, N. T. Nanavathi, and M. G. Nair
Cancer Res 1985 45: 598-600. [Abstract] [PDF]  

Protective Effects of Trifluralin on Benzo(a)pyrene-induced Tumors in A/J Mice

Elise A. Triano, Janell B. Simpson, Martha Kratky, Warren R. Lang, and Anthony J. Triolo
Cancer Res 1985 45: 601-607. [Abstract] [PDF]  

Role of Active Oxygen Species in the Photodestruction of Microsomal Cytochrome P-450 and Associated Monooxygenases by Hematoporphyrin Derivative in Rats

Mukul Das, Rakesh Dixit, Hasan Mukhtar, and David R. Bickers
Cancer Res 1985 45: 608-615. [Abstract] [PDF]  

New Assay for the O-Alkyl Cleavage Enzyme with Alkyl-lysophospholipids as Substrates

Clemens Unger, Hansjörg Eibl, Hans-Wulfard von Heyden, and Gerd Arno Nagel
Cancer Res 1985 45: 616-618. [Abstract] [PDF]  

Metabolism of N-Nitroso-2,6-dimethylmorpholine by Isozymes of Rabbit Liver Microsomal Cytochrome P-450

Demetri M. Kokkinakis, Dennis R. Koop, Dante G. Scarpelli, Minor J. Coon, and Paul F. Hollenberg
Cancer Res 1985 45: 619-624. [Abstract] [PDF]  

Collateral Sensitivity to Cross-Linking Agents Exhibited by Cultured L1210 Cells Resistant to Oxazaphosphorines

N. E. Sladek, J. E. Low, and G. J. Landkamer
Cancer Res 1985 45: 625-629. [Abstract] [PDF]  

Receptors for Plasminogen Activator, Urokinase, in Normal and Rous Sarcoma Virus-transformed Mouse Fibroblasts

Mario Del Rosso, Germana Dini, and Gabriella Fibbi
Cancer Res 1985 45: 630-636. [Abstract] [PDF]  

Intercellular Communication Capacity as a Possible Determinant of Transformation Sensitivity of BALB/c 3T3 Clonal Cells

Hiroshi Yamasaki, Taira Enomoto, Yoshiki Shiba, Yoshinobu Kanno, and Takeo Kakunaga
Cancer Res 1985 45: 637-641. [Abstract] [PDF]  

DNA Amplification and Tumorigenicity of the Human Melanoma Cell Line MeWo

Inna Shtromas, Bradley N. White, Jeanette J. A. Holden, Dorothy L. Reimer, and John C. C. Roder
Cancer Res 1985 45: 642-647. [Abstract] [PDF]  

Inhibition of Carcinogenesis by -Difluoromethylornithine in Heterotopically Transplanted Rat Urinary Bladders

Yukio Homma, Seiichiro Ozono, Isao Numata, Jerome Seidenfeld, and Ryoichi Oyasu
Cancer Res 1985 45: 648-652. [Abstract] [PDF]  

Effects of Photosensitization by Hematoporphyrin Derivative on Mitochondrial Adenosine Triphosphatase-mediated Proton Transport and Membrane Integrity of R3230AC Mammary Adenocarcinoma

David S. Perlin, Richard S. Murant, Scott L. Gibson, and Russell Hilf
Cancer Res 1985 45: 653-658. [Abstract] [PDF]  

Morphological Observations during Developing Concomitant Immunity against a C3H/He Mammary Tumor

Jan Vaage and Karen G. Pepin
Cancer Res 1985 45: 659-666. [Abstract] [PDF]  

Specific Stimulation by Phorbol Esters of the Phosphorylation of Histones H2B and H4 in Murine Lymphocytes

George J. Patskan and C. Stuart Baxter
Cancer Res 1985 45: 667-672. [Abstract] [PDF]  

Differential Cytokeratin and -Fetoprotein Expression in Morphologically Distinct Epithelial Cells Emerging at the Early Stage of Rat Hepatocarcinogenesis

Lucie Germain, René Goyette, and Normand Marceau
Cancer Res 1985 45: 673-681. [Abstract] [PDF]  

Variability of Androgen-related Phenotypes in the Shionogi Mammary Carcinoma during Growth, Involution, Recurrence, and Progression to Hormonal Independence

Nicholas Bruchovsky, Paul S. Rennie, Navdeep Otal, Adrian Vanson, Martin Giles, and Hugh Pontifex
Cancer Res 1985 45: 682-689. [Abstract] [PDF]  

Partial Characterization of a Cell Motility Factor from Human Urine

Gerald W. Chodak, Michael Klagsbrun, and Yuen W. Shing
Cancer Res 1985 45: 690-694. [Abstract] [PDF]  

Therapeutic and Diabetogenic Potential of Two Newly Synthesized Nitrosoureido Sugars

Ralph J. Bernacki, Glenn L. Wilson, Brooke T. Mossman, Norman Angelino, Peter M. Kanter, and Walter Korytnyk
Cancer Res 1985 45: 695-702. [Abstract] [PDF]  

Identification of a High-Frequency Model for Renal Carcinoma by the Induction of Renal Tumors in the Mouse with a Single Dose of Streptozotocin

Gordon C. Hard
Cancer Res 1985 45: 703-708. [Abstract] [PDF]  

Characterization of Monoclonal Antibodies to the Estrogen-regulated M_r 52,000 Glycoprotein and Their Use in MCF7 Cells

Marcel Garcia, Françoise Capony, Danielle Derocq, Dominique Simon, Bernard Pau, and Henri Rochefort
Cancer Res 1985 45: 709-716. [Abstract] [PDF]  

Effects of Amsacrine and Other DNA-intercalating Drugs on Nuclear and Nucleolar Structure in Cultured V79 Chinese Hamster Cells and PtK₂ Rat Kangaroo Cells

Cynthia G. Jensen, William R. Wilson, and A. Robert Bleumink
Cancer Res 1985 45: 717-725. [Abstract] [PDF]  

Evidence for Multiple Steps in Neoplastic Transformation of Normal and Preneoplastic Syrian Hamster Embryo Cells following Transfection with Harvey Murine Sarcoma Virus Oncogene (v-Ha-ras)

David G. Thomassen, Tona M. Gilmer, Lois A. Annab, and J. Carl Barrett
Cancer Res 1985 45: 726-732. [Abstract] [PDF]  

Effects of Tubulozole on the Microtubule System of Cells in Culture and in Vivo

Gustaaf M. A. Geuens, Rony M. Nuydens, Rudy E. Willebrords, Roger M. L. Van de Veire, Frans Goossens, Christian H. Dragonetti, Marc M. K. Mareel, and Marc J. De Brabander
Cancer Res 1985 45: 733-742. [Abstract] [PDF]  

Selective Protein Phosphorylation in Heterogeneous Subpopulations of Human Colon Carcinoma Cells

Subhas Chakrabarty, Yih Jan, Charles A. Miller, and Michael G. Brattain
Cancer Res 1985 45: 743-750. [Abstract] [PDF]  

Anti-Transferrin Receptor Antibody Linked to Pseudomonas Exotoxin as a Model Immunotoxin in Human Ovarian Carcinoma Cell Lines

Robert Pirker, David J. P. FitzGerald, Thomas C. Hamilton, Robert F. Ozols, Mark C. Willingham, and Ira Pastan
Cancer Res 1985 45: 751-757. [Abstract] [PDF]  

Effects of Monoclonal Antibody and Complement Treatment of Human Marrow on Hematopoiesis in Continuous Bone Marrow Culture

Joel S. Greenberger, Lisa Rothstein, Paolo DeFabritiis, Marco Bregni, Robert Bast, Jr., Jerome Ritz, Lee M. Nadler, Jeffrey M. Lipton, and Mary Ann Sakakeeny
Cancer Res 1985 45: 758-767. [Abstract] [PDF]  

Tumor Phenotype and Susceptibility to Progression as an Expression of Subpopulations of Initiated Murine Cells

F. F. Becker
Cancer Res 1985 45: 768-773. [Abstract] [PDF]  

Malignant Transformation of a Cloned, Nontumorigenic Mouse Epidermal Keratinocyte Cell Line, MSK-C3H-NU, by 7,12-Dimethylbenz(a)anthracene

Katsuhiko Indo and Hideki Miyaji
Cancer Res 1985 45: 774-782. [Abstract] [PDF]  

Isolation and Characterization of a Monoclonal Antibody Specific for Epithelial Cells

Anne W. Hamburger, Yvonne A. Reid, Barbara Pelle, George E. Milo, Inge Noyes, Henry Krakauer, and J. Peter Fuhrer
Cancer Res 1985 45: 783-790. [Abstract] [PDF]  

Expression of Maturation-specific Nuclear Antigens in Differentiating Human Myeloid Leukemia Cells

Shin-ichi Murao, Alan L. Epstein, Charles V. Clevenger, and Eliezer Huberman
Cancer Res 1985 45: 791-795. [Abstract] [PDF]  

Pharmacological, lexicological, and Therapeutic Evaluation in Mice of Doxorubicin Entrapped in Cardiolipin Liposomes

Aquilur Rahman, Geoffrey White, Newton More, and Philip S. Schein
Cancer Res 1985 45: 796-803. [PDF]  

Disulfide Bonding of a Human Prostate Tumor-associated Membrane Antigen Recognized by Monoclonal Antibody D83.21

James J. Starling and George L. Wright, Jr.
Cancer Res 1985 45: 804-808. [Abstract] [PDF]  

Promoting Effect of Nicotinamide on the Development of Renal Tubular Cell Tumors in Rats Initiated with Diethylnitrosamine

Mark R. Rosenberg, Deborah L. Novicki, Randy L. Jirtle, Alan Novotny, and George Michalopoulos
Cancer Res 1985 45: 809-814. [Abstract] [PDF]  

High-Molecular-Weight Glycoproteins of Human Teratocarcinoma Defined by Monoclonal Antibodies to Carbohydrate Determinants

Wolfgang J. Rettig, Carlos Cordon-Cardo, Jennifer S. C. Ng, Herbert F. Oettgen, Lloyd J. Old, and Kenneth O. Lloyd
Cancer Res 1985 45: 815-821. [Abstract] [PDF]  

Relationship of c-myc Expression to Differentiation and Proliferation of HL-60 Cells

J. Filmus and R. N. Buick
Cancer Res 1985 45: 822-825. [Abstract] [PDF]  

Biochemical Analysis of Human Ovarian Cancer-associated Antigens Defined by Murine Monoclonal Antibodies

Silvia Miotti, Salvatore Aguanno, Silvana Canevari, Alessandro Diotti, Rosaria Orlandi, Sandro Sonnino, and Maria I. Colnaghi
Cancer Res 1985 45: 826-832. [Abstract] [PDF]  

Influence of Spatial Configuration of Carcinoma Cell Populations on the Expression of a Tumor-associated Glycoprotein

Patricia Horan Hand, David Colcher, David Salomon, Jeanette Ridge, Philip Noguchi, and Jeffrey Schlom
Cancer Res 1985 45: 833-840. [Abstract] [PDF]  

Keratin Expression in Normal Esophageal Epithelium and Squamous Cell Carcinoma of the Esophagus

Michael P. Grace, Kwan Hee Kim, Lawrence D. True, and Elaine Fuchs
Cancer Res 1985 45: 841-846. [Abstract] [PDF]  

Transcriptional Regulation of c-myc during Chemically Induced Differentiation of HL-60 Cultures

Leonard E. Grosso and Henry C. Pitot
Cancer Res 1985 45: 847-850. [Abstract] [PDF]  

Leukoregulin, a Direct-acting Anticancer Immunological Hormone That Is Distinct from Lymphotoxin and Interferon

Janet H. Ransom, Charles H. Evans, Richard P. McCabe, Nicholas Pomato, Jeffrey A. Heinbaugh, Marcia Chin, and Michael G. Hanna, Jr.
Cancer Res 1985 45: 851-862. [Abstract] [PDF]  

Clinical and Epidemiological Investigations:

A Randomized Study of Low and High Doses of Leukocyte -Interferon in Metastatic Renal Cell Carcinoma: The American Cancer Society Collaborative Trial

John M. Kirkwood, Jules E. Harris, Raul Vera, Steven Sandler, David S. Fischer, Janardan Khandekar, Marc S. Ernstoff, Leo Gordon, Richard Lutes, Philip Bonomi, Bernard Lytton, M. Cobleigh, and Samuel J. Taylor, IV
Cancer Res 1985 45: 863-871. [Abstract] [PDF]  

A Serological Case-Control Study of Primary Hepatocellular Carcinoma in Guangxi, China

Fu-Sun Yeh, Chi-Chun Mo, Si Luo, Brian E. Henderson, Myron J. Tong, and Mimi C. Yu
Cancer Res 1985 45: 872-873. [Abstract] [PDF]  

Augmented Immunity in Cancer Patients Treated with -Interferon

John R. Neefe, James E. Sullivan, Marilyn Ayoob, Elizabeth Phillips, and Frederick P. Smith
Cancer Res 1985 45: 874-878. [Abstract] [PDF]  

Human Anti-Murine Immunoglobulin Responses in Patients Receiving Monoclonal Antibody Therapy

Robert W. Schroff, Kenneth A. Foon, Shannon M. Beatty, Robert K. Oldham, and Alton C. Morgan, Jr.
Cancer Res 1985 45: 879-885. [Abstract] [PDF]  

Prognostic Importance of Prostate-specific Antigen for Monitoring Patients with Stages B₂ to D₁ Prostate Cancer

Carl S. Killian, Norman Yang, Lawrence J. Emrich, Farida P. Vargas, Manabu Kuriyama, Ming C. Wang, Nelson H. Slack, Lawrence D. Papsidero, Gerald P. Murphy, T. Ming Chu, and the Investigators of the National Prostatic Cancer Project
Cancer Res 1985 45: 886-891. [Abstract] [PDF]  

Human Placental Alkaline Phosphatase in Benign and Malignant Ovarian Neoplasia

Etienne J. Nouwen, Dirk E. Pollet, Jacques B. Schelstraete, Marlène W. Eerdekens, Christian Hänsch, André Van de Voorde, and Marc E. De Broe
Cancer Res 1985 45: 892-902. [Abstract] [PDF]  

Translocation of Phospholipid-sensitive Ca²⁺-dependent Protein Kinase and Its Substrate, M_r 38,000 Protein, in Chronic Myelocytic and Acute Myelocytic Leukemias

Keisuke Sakurada, Tamotsu Miyazaki, Kazuhiro Kimura, Mitsuhisa Yamabe, Fumio Katabami, Minoru Koyama, Yoshio Uehara, and Norio Katoh
Cancer Res 1985 45: 903-908. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: S. D. Vesselinovitch and N. Mihailovich. Kinetics of Diethylnitrosamine Hepatocarcinogenesis in the Infant Mouse. Cancer Res., 43: 4253–4259, 1983

Stanley Goldfarb, Thomas D. Pugh, Steven Kosciuk, and Joshua Chover
Cancer Res 1985 45: 909-910. [PDF]  

Correspondence re: S. D. Vesselinovitch and N. Mihailovich. Kinetics of Diethylnitrosamine Hepatocarcinogenesis in the Infant Mouse. Cancer Res., 43: 4253–4259, 1983—Reply

S. D. Vesselinovitch and N. Mihailovich
Cancer Res 1985 45: 910-912. [PDF]  

Correspondence re: Z. R. Shi, L. V. McIntyre, B. B. Knowles, D. Salter, and Y. S. Kim. Expression of a Carbohydrate Differentiation Antigen, Stage-specific Embryonic Antigen 1, in Human Colonic Adenocarcinoma. Cancer Res., 44: 1142–1147, 1984

Robert H. Riddell and Catherine M. Listinsky
Cancer Res 1985 45: 913 [PDF]  

Correspondence re: Z. R. Shi, L. V. McIntyre, B. B. Knowles, D. Salter, and Y. S. Kim. Expression of a Carbohydrate Differentiation Antigen, Stage-specific Embryonic Antigen 1, in Human Colonic Adenocarcinoma. Cancer Res., 44: 1142–1147, 1984—Reply

Young S. Kim and Steven H. Itzkowitz
Cancer Res 1985 45: 913 [PDF]  

Meeting Reports:

A National Institutes of Health Workshop Report: Chemical Carcinogenesis and the Oncogenes—A Chemical Pathology Study Section Workshop

G. Tim Bowden
Cancer Res 1985 45: 914-918. [PDF]  

Seventh Annual Interdisciplinary Cancer Research Workshop

Peter Politzer and Cyril Parkanyi
Cancer Res 1985 45: 919-921. [PDF]  

Monitoring of Aflatoxins in Human Body Fluids and Application to Field Studies

Colin Garner, Robin Ryder, and Ruggero Montesano
Cancer Res 1985 45: 922-928. [PDF]  

Articles:

Announcements

Cancer Res 1985 45: 929-931. [PDF]  

Recent Deaths

Cancer Res 1985 45: 931 [PDF]  

Errata:

Sodium Butyrate Induction of Milk-related Antigens in Human MCF-7 Breast Carcinoma Cells

Cancer Res 1985 45: 931 [PDF]  

Phase l-ll Trial of High-Dose Calcium Leucovorin and 5-Fluorouracil in Advanced Colorectal Cancer

Cancer Res 1985 45: 931 [PDF]  

Pharmacokinetics of 5-Fluorouracil Following Different Routes of Intrahepatic Administration in the Canine Model

Cancer Res 1985 45: 931 [PDF]  

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