Perspectives in Cancer Research:

Hereditary Cancer, Oncogenes, and Antioncogenes

Alfred G. Knudson, Jr.
Cancer Res 1985 45: 1437-1443. [PDF]  

Basic Sciences:

Effects of Inhibitors of Polyamine Biosynthesis on the Growth and Melanogenesis of Murine Melanoma Cells

Kirsti Käpyaho, Riitta Sinervirta, and Juhani Jänne
Cancer Res 1985 45: 1444-1448. [Abstract] [PDF]  

Tumorigenicity of 5-Methylchrysene Dihydrodiols and Dihydrodiol Epoxides in Newborn Mice and on Mouse Skin

Stephen S. Hecht, Lynn Radok, Shantu Amin, Keith Huie, Assieh A. Melikian, Dietrich Hoffmann, John Pataki, and Ronald G. Harvey
Cancer Res 1985 45: 1449-1452. [Abstract] [PDF]  

Heterogeneity in the Sensitivities of the 13762NF Rat Mammary Adenocarcinoma Cell Clones to Cytolysis Mediated by Extra- and Intratumoral Macrophages

Susan M. North and Garth L. Nicolson
Cancer Res 1985 45: 1453-1458. [Abstract] [PDF]  

Cell Cycle-dependent Heat Sensitization of Murine Granulocyte-Macrophage Progenitor Cells in Regenerating Marrow

Eiji Kobayashi, Morihisa Yamagishi, Takayuki Kamamoto, Yataro Yoshida, and Haruto Uchino
Cancer Res 1985 45: 1459-1463. [Abstract] [PDF]  

Cell-mediated Inhibition of Tumor Colony Formation in Agarose by Resting and Interleukin 2-stimulated Human Lymphocytes

Edward C. Bradley, Joseph J. Catino, Brian F. Issell, Bernard Poiesz, Julie M. Hustad, Traci Dalton, Mark Allegretta, and James Mier
Cancer Res 1985 45: 1464-1468. [Abstract] [PDF]  

Initiation of Urinary Bladder Carcinogenesis in Rats by Freeze Ulceration with Sodium Saccharin Promotion

Ryohei Hasegawa, Robert E. Greenfield, Gen'i Murasaki, Toru Suzuki, and Samuel M. Cohen
Cancer Res 1985 45: 1469-1473. [Abstract] [PDF]  

Regulation of Melanin Synthesis of B16 Mouse Melanoma Cells by 1,25-Dihydroxyvitamin D₃ and Retinoic Acid

Junichi Hosoi, Etsuko Abe, Tatsuo Suda, and Toshio Kuroki
Cancer Res 1985 45: 1474-1478. [Abstract] [PDF]  

Intestinal Uptake of Hexoses and Fatty Acids in Tumor-bearing Rats

A. B. R. Thomson, P. S. Rennie, K. Walker, and C. Cheeseman
Cancer Res 1985 45: 1479-1482. [Abstract] [PDF]  

Genetically Determined Susceptibility of Fischer 344 Rats to Propylnitrosourea-induced Thymic Lymphomas

Hayase Shisa and Hiroshi Hiai
Cancer Res 1985 45: 1483-1487. [Abstract] [PDF]  

Similar Differential for Total Polyglutamylation and Cytotoxicity among Various Folate Analogues in Human and Murine Tumor Cells in Vitro

Lawrence L. Samuels, Donna M. Moccio, and Francis M. Sirotnak
Cancer Res 1985 45: 1488-1495. [Abstract] [PDF]  

Induction of Tumoricidal Activity of Polymorphonuclear Leukocytes by a Linear ß-1,3-D-Glucan and Other Immunomodulators in Murine Cells

Kaoru Morikawa, Reiko Takeda, Masatoshi Yamazaki, and Den'ichi Mizuno
Cancer Res 1985 45: 1496-1501. [Abstract] [PDF]  

Host-mediated Therapeutic Effects Produced by Appropriately Timed Administration of Bleomycin on a Rat Fibrosarcoma

Kiyoshi Morikawa, Masuo Hosokawa, Jun-ichi Hamada, Michio Sugawara, and Hiroshi Kobayashi
Cancer Res 1985 45: 1502-1506. [Abstract] [PDF]  

Metabolism of 3-tert-Butyl-4-hydroxyanisole to 3-tert-Butyl-4,5-dihydroxyanisole by Rat Liver Microsomes

Karon E. Armstrong and Lee W. Wattenberg
Cancer Res 1985 45: 1507-1510. [Abstract] [PDF]  

Cytotoxic Efficacy of Reconstituted and Stored Antitumor Agents

Li-Ying Yang and Benjamin Drewinko
Cancer Res 1985 45: 1511-1515. [Abstract] [PDF]  

Quantitation of the Rate of Spontaneous Generation and Carcinogen-induced Frequency of Anchorage-independent Variants of Rat Tracheal Epithelial Cells in Culture

David G. Thomassen, Paul Nettesheim, Thomas E. Gray, and J. Carl Barrett
Cancer Res 1985 45: 1516-1524. [Abstract] [PDF]  

Differential Sensitivity of Human Breast Cancer Cell Lines to the Growth-inhibitory Effects of Tamoxifen

Roger R. Reddel, Leigh C. Murphy, Rosemary E. Hall, and Robert L. Sutherland
Cancer Res 1985 45: 1525-1531. [Abstract] [PDF]  

Effects of Total-Body Hyperthermia on Metastases from Experimental Mouse Tumors

Masayuki Oda, Shigemasa Koga, and Michio Maeta
Cancer Res 1985 45: 1532-1535. [Abstract] [PDF]  

Experimental Radiotherapy of Murine Lymphoma with ¹³¹I-labeled Anti-Thy 1.1 Monoclonal Antibody

Christopher C. Badger, Kenneth A. Krohn, Arthur V. Peterson, Howard Shulman, and Irwin D. Bernstein
Cancer Res 1985 45: 1536-1544. [Abstract] [PDF]  

Clearance Studies of Methotrexate in Dogs after Multiple-Rate Infusion

Chung Y. Lui, Myung G. Lee, and Win L. Chiou
Cancer Res 1985 45: 1545-1548. [Abstract] [PDF]  

Restoration of Sensitivity to Oxazaphosphorines by Inhibitors of Aldehyde Dehydrogenase Activity in Cultured Oxazaphosphorine-resistant L1210 and Cross-Linking Agent-resistant P388 Cell Lines

N. E. Sladek and G. J. Landkamer
Cancer Res 1985 45: 1549-1555. [Abstract] [PDF]  

Comutagenic Effects of 3-Aminobenzamide in Chinese Hamster Ovary Cells

Jeffrey L. Schwartz, William F. Morgan, Patricia Brown-Lindquist, Veena Afzal, Ralph R. Weichselbaum, and Sheldon Wolff
Cancer Res 1985 45: 1556-1559. [Abstract] [PDF]  

Full Expression of Blood Group-related, Transplantation-related, and Carcinoembryonic Antigens in Human Colorectal Cancer Cells with Different Degrees of Phenotypic Differentiation

Benjamin Drewinko and Benjamin Lichtiger
Cancer Res 1985 45: 1560-1564. [Abstract] [PDF]  

Type I and II Cyclic Adenosine 3':5'-Monophosphate-dependent Protein Kinase in Human Gastric Mucosa and Carcinomas

Wataru Yasui, Hiromichi Sumiyoshi, Atsushi Ochiai, Mikimasa Yamahara, and Eiichi Tahara
Cancer Res 1985 45: 1565-1568. [Abstract] [PDF]  

Depression of the Hepatic Cytochrome P-450 Monooxygenase System by Treatment of Mice with the Antineoplastic Agent 5-Azacytidine

N. J. Gooderham and G. J. Mannering
Cancer Res 1985 45: 1569-1572. [Abstract] [PDF]  

Regulation of Reticulum Cell Sarcoma Tumor Growth in SJL/J Mice by a Serum Inhibitor Affecting T-Cell Proliferation

Takashi Sakano, Stanley M. Wilbur, and Benjamin Bonavida
Cancer Res 1985 45: 1573-1578. [Abstract] [PDF]  

Determinants of Deoxyadenosine Toxicity in Hybrids between Human T- and B-Lymphoblasts as a Model for the Development of Drug Resistance in T-Cell Acute Lymphoblastic Leukemia

Joanne Kurtzberg and Michael S. Hershfield
Cancer Res 1985 45: 1579-1586. [Abstract] [PDF]  

Analysis of Glucocorticoid-resistant Human Leukemic Cells by Somatic Cell Hybridization

Jeffrey M. Harmon, E. Brad Thompson, and Kelley A. Baione
Cancer Res 1985 45: 1587-1593. [Abstract] [PDF]  

Species- and Length of Exposure-dependent Differences in the Benzo(a)pyrene:DNA Adducts Formed in Embryo Cell Cultures from Mice, Rats, and Hamsters

Said M. Sebti, Donna Pruess-Schwartz, and William M. Baird
Cancer Res 1985 45: 1594-1600. [Abstract] [PDF]  

Effects of Clumps and Clusters on Survival Measurements with Clonogenic Assays

Sara Rockwell
Cancer Res 1985 45: 1601-1607. [Abstract] [PDF]  

Oxygen Dependence of the Photosensitizing Effect of Hematoporphyrin Derivative in NHIK 3025 Cells

Johan Moan and Stein Sommer
Cancer Res 1985 45: 1608-1610. [Abstract] [PDF]  

Effect of Estrogens and Antiestrogens on Growth-regulatory Enzymes in Human Breast Cancer Cells in Tissue Culture

Susan C. Aitken and Marc E. Lippman
Cancer Res 1985 45: 1611-1620. [Abstract] [PDF]  

Effect of Bile Salts on Rates of Formation, Accumulation, and Export of Mutagenic Metabolites from Benzo(a)pyrene Produced by the Perfused Rat Liver

Frank W. Kari, F. C. Kauffman, and R. G. Thurman
Cancer Res 1985 45: 1621-1627. [Abstract] [PDF]  

Presence and Regulation of Tyrosinase Activity in Human Neuroblastoma Cell Variants in Vitro

Robert A. Ross and June L. Biedler
Cancer Res 1985 45: 1628-1632. [Abstract] [PDF]  

Suppression of DNA Synthesis in NEL-M1 Human Melanoma Cells by Triamcinolone Acetonide

Dennis M. DiSorbo, Nancy A. Harris, and Larry Nathanson
Cancer Res 1985 45: 1633-1637. [Abstract] [PDF]  

Oxidative Properties of 12-O-Tetradecanoylphorbol-13-acetate-stimulated Human Blood Monomorphonuclear Leukocytes and Their Toxicity against a Human Lung Carcinoma Cell Line

Andreas Gescher, Ann E. Brodie, and Donald J. Reed
Cancer Res 1985 45: 1638-1643. [Abstract] [PDF]  

Effects of Estrogen and Tamoxifen on the Regulation of Dihydrofolate Reductase Gene Expression in a Human Breast Cancer Cell Line

Richard M. Levine, Elizabeth Rubalcaba, Marc E. Lippman, and Kenneth H. Cowan
Cancer Res 1985 45: 1644-1650. [Abstract] [PDF]  

Verapamil-induced Augmentation of Etoposide Accumulation in L1210 Cells in Vitro

Jack C. Yalowich and Warren E. Ross
Cancer Res 1985 45: 1651-1656. [Abstract] [PDF]  

Adoptive Immunotherapy of Newly Induced Murine Sarcomas

Suyu Shu and Steven A. Rosenberg
Cancer Res 1985 45: 1657-1662. [Abstract] [PDF]  

Murine Tumor Cell Lysis by Antibody-dependent Macrophage-mediated Cytotoxicity Using Syngeneic Monoclonal Antibodies

Ichiro Kawase, Kiyoshi Komuta, Takeshi Ogura, Hiromi Fujiwara, Toshiyuki Hamaoka, and Susumu Kishimoto
Cancer Res 1985 45: 1663-1668. [Abstract] [PDF]  

Altered Mouse Bone Marrow Glutathione and Glutathione Transferase Levels in Response to Cytotoxins

David J. Adams, James Carmichael, and C. Roland Wolf
Cancer Res 1985 45: 1669-1673. [Abstract] [PDF]  

DNA Damage and Differential Cytotoxicity Produced in Human Cells by 2-Chloroethyl (Methylsulfonyl)methanesulfonate (NSC 338947), a New DNA-chloroethylating Agent

Neil W. Gibson, Leonard C. Erickson, and Kurt W. Kohn
Cancer Res 1985 45: 1674-1679. [Abstract] [PDF]  

Formation of Unique Arylamine:DNA Adducts from 2-Aminofluorene Activated by Prostaglandin H Synthase

Robert S. Krauss and Thomas E. Eling
Cancer Res 1985 45: 1680-1686. [Abstract] [PDF]  

Anthracycline Resistance in P388 Murine Leukemia and Its Circumvention by Calcium Antagonists

David Kessel and Cynthia Wilberding
Cancer Res 1985 45: 1687-1691. [Abstract] [PDF]  

Regional Measurements of [¹⁴C]Misonidazole Distribution and Blood Flow in Subcutaneous RT-9 Experimental Tumors

Ronald Blasberg, Marc Horowitz, John Strong, Peter Molnar, Clifford Patlak, Ernest Owens, and Joseph Fenstermacher
Cancer Res 1985 45: 1692-1701. [Abstract] [PDF]  

Thyroid Hormone Modulation of Transformation Induced by Kirsten Murine Sarcoma Virus

Carmia Borek, Augustinus Ong, and Johng S. Rhim
Cancer Res 1985 45: 1702-1706. [Abstract] [PDF]  

Reexpression of Fetal Characters in Simian Virus 40-transformed Human Keratinocytes

Bruno A. Bernard, Shirley M. Robinson, Alix Semat, and Michel Darmon
Cancer Res 1985 45: 1707-1716. [Abstract] [PDF]  

Characterization of Dihydrofolate Reductase-related DNA and RNA from Human KB Cell Subclones Containing Different Amounts of Enzyme

Jacques Bouchard, Kenneth F. Bastow, Milbrey Cate Starnes, Rekha Prabhu, and Yung-chi Cheng
Cancer Res 1985 45: 1717-1722. [Abstract] [PDF]  

Identification and Localization of Human Pancreatic Tumor-associated Antigens by Monoclonal Antibodies to RWP-1 and RWP-2 Cells

Jade Chin and Frederick Miller
Cancer Res 1985 45: 1723-1729. [Abstract] [PDF]  

Detection of Messenger RNAs of -Fetoprotein and Albumin in a Human Hepatoma Cell Line by in Situ Hybridization

Jan Breborowicz and Taiki Tamaoki
Cancer Res 1985 45: 1730-1736. [Abstract] [PDF]  

Defective DNA Cross-Link Removal in Chinese Hamster Cell Mutants Hypersensitive to Bifunctional Alkylating Agents

C. A. Hoy, L. H. Thompson, C. L. Mooney, and E. P. Salazar
Cancer Res 1985 45: 1737-1743. [Abstract] [PDF]  

Immunoperoxidase Localization of a High-Molecular-Weight Mucin Recognized by Monoclonal Antibody 1D₃

Aniruddha Gangopadhyay, Malaya Bhattacharya, Sunil K. Chatterjee, Joseph J. Barlow, and Yoshiaki Tsukada
Cancer Res 1985 45: 1744-1752. [Abstract] [PDF]  

Antineoplastic Effects in Rats of 5-Fluorocytosine in Combination with Cytosine Deaminase Capsules

Tadashi Nishiyama, Yasuo Kawamura, Keiji Kawamoto, Hiroshi Matsumura, Norimi Yamamoto, Tomiyoshi Ito, Akio Ohyama, Tohoru Katsuragi, and Takuo Sakai
Cancer Res 1985 45: 1753-1761. [Abstract] [PDF]  

Variation in Histology and Growth Characteristics of Transplantable Marek's Disease Lymphomas

Oscar J. Fletcher and Louis W. Schierman
Cancer Res 1985 45: 1762-1765. [Abstract] [PDF]  

Two-Dimensional Electrophoretic Analysis of Human Prostatic Fluid Proteins

Juan Guevara, Jr., Barbara H. Herbert, and Chung Lee
Cancer Res 1985 45: 1766-1771. [Abstract] [PDF]  

Effect of Tunicamycin on Release of Macromolecules and Tumor Antigens by Human Melanoma Cells

Dean Johnston and Jean-Claude Bystryn
Cancer Res 1985 45: 1772-1777. [Abstract] [PDF]  

Activity of Mitozolomide (NSC 353451), a New Imidazotetrazine, against Xenografts from Human Melanomas, Sarcomas, and Lung and Colon Carcinomas

Øystein Fodstad, Steinar Aamdal, Alexander Pihl, and Michael R. Boyd
Cancer Res 1985 45: 1778-1786. [Abstract] [PDF]  

Localization of Plasminogen Activators in Human Colon Cancer by Immunoperoxidase Staining

Shin Kohga, Shashikumar R. Harvey, Ruth M. Weaver, and Gabor Markus
Cancer Res 1985 45: 1787-1796. [Abstract] [PDF]  

Antitumor Activity and Minimal Toxicity of Concentrated Thymidine Infused in Nude Mice

Arnold Lockshin, Beppino C. Giovanella, John S. Stehlin, Jr., Tony Kozielski, Carlos Quian, and Richard W. Apperson
Cancer Res 1985 45: 1797-1802. [Abstract] [PDF]  

Modulation of Rat Mammary Carcinogenesis by Indomethacin

David L. McCormick, Madelynn J. Madigan, and Richard C. Moon
Cancer Res 1985 45: 1803-1808. [Abstract] [PDF]  

Nucleotide Sequence Preservation of Human Leukemic Mitochondrial DNA

Raymond J. Monnat, Jr., Clare L. Maxwell, and Lawrence A. Loeb
Cancer Res 1985 45: 1809-1814. [Abstract] [PDF]  

Evolution of Methotrexate Resistance of Human Acute Lymphoblastic Leukemia Cells in Vitro

Takao Ohnuma, Ruju Julia Lo, Kevin J. Scanlon, Barton A. Kamen, Taisuke Ohnoshi, Sandra R. Wolman, and James F. Holland
Cancer Res 1985 45: 1815-1822. [Abstract] [PDF]  

Amplification of the c-myc Oncogene in a Subpopulation of Human Small Cell Lung Cancer

Kalle Saksela, Jonas Bergh, Veli-Pekka Lehto, Kenneth Nilsson, and Kari Alitalo
Cancer Res 1985 45: 1823-1827. [Abstract] [PDF]  

Induction of Epidermoid Differentiation by Cyclic Adenine Nucleotide in Cultured Mammary Tumors of Mice

Frederick V. Schaefer, R. Philip Custer, and Sam Sorof
Cancer Res 1985 45: 1828-1833. [Abstract] [PDF]  

Effects of Ricin A Chain Conjugates of Monoclonal Antibodies to Human -Fetoprotein and Placental Alkaline Phosphatase on Antigen-producing Tumor Cells in Culture

Katsumi Tsukazaki, Edward G. Hayman, and Erkki Ruoslahti
Cancer Res 1985 45: 1834-1838. [Abstract] [PDF]  

Development and Progression of Karyotypic Variability in Melanoma K1735 following X-Irradiation

Sandra R. Wolman, Lydia E. McMorrow, Isaiah J. Fidler, and James E. Talmadge
Cancer Res 1985 45: 1839-1844. [Abstract] [PDF]  

Induction of Rat Pancreatic B-Cell Tumors by the Combined Administration of Streptozotocin or Alloxan and Poly(Adenosine Diphosphate Ribose) Synthetase Inhibitors

Takashi Yamagami, Atsuo Miwa, Shin Takasawa, Hiroshi Yamamoto, and Hiroshi Okamoto
Cancer Res 1985 45: 1845-1849. [Abstract] [PDF]  

Clinical and Epidemiological Investigations:

Hyaluronic Acid Content of Effusions as a Diagnostic Aid for Malignant Mesothelioma

John Roboz, John Greaves, Demetra Silides, A. Philippe Chahinian, and James F. Holland
Cancer Res 1985 45: 1850-1854. [Abstract] [PDF]  

Demographic Study of Clinically Atypical (Dysplastic) Nevi in Patients with Melanoma and Comparison Subjects

James J. Nordlund, John Kirkwood, Bernadette M. Forget, Adrianna Scheibner, Daniel M. Albert, Emmanuel Lemer, and G. W. Milton
Cancer Res 1985 45: 1855-1861. [Abstract] [PDF]  

Phase I and Clinical Pharmacological Evaluation of 4'-Deoxydoxorubicin in Patients with Advanced Cancer

Gail F. Stanton, Virginia Raymond, Robert E. Wittes, Philip Schulman, Daniel Budman, Raquel Baratz, Linda Williams, Gina R. Petroni, Nancy L. Geller, Counce Hancock, Willi Kreis, and Charles W. Young
Cancer Res 1985 45: 1862-1868. [Abstract] [PDF]  

Phase I and Clinical Pharmacological Study of Mercaptopurine Administered as a Prolonged Intravenous Infusion

Solomon Zimm, Lawrence J. Ettinger, John S. Holcenberg, Barton A. Kamen, Teresa J. Vietti, Jean Belasco, Nancy Cogliano-Shutta, Frank Balis, Lawrence E. Lavi, Jerry M. Collins, and David G. Poplack
Cancer Res 1985 45: 1869-1873. [Abstract] [PDF]  

Phase I Study and Pharmacokinetics of Weekly High-Dose 13-cis-Retinoic Acid

Gerald Clamon, Guy G. Chabot, Frederick Valeriote, Enrique Davilla, Charles Vogel, Elizabeth Gorowski, and Robert Birch
Cancer Res 1985 45: 1874-1878. [Abstract] [PDF]  

Disposition of Mitoxantrone in Cancer Patients

David S. Alberts, Yei-Mei Peng, Susan Leigh, Thomas P. Davis, and David L. Woodward
Cancer Res 1985 45: 1879-1884. [Abstract] [PDF]  

Pharmacokinetics of Melphalan in Clinical Isolation Perfusion of the Extremities

Henry A. Briele, Michael Djuric, Donald T. Jung, Thomas Mortell, Minu K. Patel, and Tapas K. Das Gupta
Cancer Res 1985 45: 1885-1889. [Abstract] [PDF]  

Peanut Agglutinin, a Marker for T-Cell Acute Lymphoblastic Leukemia with a Good Prognosis

A. J. P. Veerman, P. H. G. Hogeman, D. R. Huismans, C. H. Van Zantwijk, and P. D. Bezemer
Cancer Res 1985 45: 1890-1893. [Abstract] [PDF]  

Use of a Monoclonal Antibody (B72.3) as an Immunocytochemical Adjunct to Diagnosis of Adenocarcinoma in Human Effusions

William W. Johnston, Cheryl A. Szpak, S. Chace Lottich, Ann Thor, and Jeffrey Schlom
Cancer Res 1985 45: 1894-1900. [Abstract] [PDF]  

Sialosylated Lewis^x in the Sera of Cancer Patients Detected by a Cell-binding Inhibition Assay

Masaki Hirota, Kiyoyasu Fukushima, Paul I. Terasaki, Glenn Y. Terashita, Masaaki Kawahara, David Chia, Naofumi Suyama, and Hiroyuki Togashi
Cancer Res 1985 45: 1901-1905. [Abstract] [PDF]  

Letter to the Editor:

Role of Opium in Esophageal Cancer: A Hypothesis

Kambiz Dowlatshahi and Richard J. Miller
Cancer Res 1985 45: 1906-1907. [PDF]  

Meeting Report:

U.S.-Japan Cooperative Cancer Research Program Seminar on Carcinogenicity, Mutagenicity, and Metabolism of Heterocyclic Amines

Snorri S. Thorgeirsson and Shigeaki Sato
Cancer Res 1985 45: 1908-1911. [PDF]  

Articles:

Special Announcements

Cancer Res 1985 45: 1912-1913. [PDF]  

Announcements

Cancer Res 1985 45: 1914 [PDF]  

Announcements:

Recent Deaths

Cancer Res 1985 45: 1914 [PDF]  

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