Perspectives in Cancer Research:

Cancer as a Dynamic Developmental Disorder

Harry Rubin
Cancer Res 1985 45: 2935-2942. [PDF]  

Special Lecture:

Selectivity—Key to Chemotherapy: Presidential Address

Gertrude B. Elion
Cancer Res 1985 45: 2943-2950. [PDF]  

Basic Sciences:

Inhibition of Benzo(a)pyrene and Benzo(a)pyrene-trans-7,8-diol Metabolism and DNA Binding in Mouse Lung Explants by Ellagic Acid

Rakesh Dixit, Robert W. Teel, F. Bernard Daniel, and Gary D. Stoner
Cancer Res 1985 45: 2951-2956. [Abstract] [PDF]  

Effects of Human Recombinant ₂ arg-Interferon and -Interferon on Human Breast Cancer Cell Lines: Dissociation of Antiproliferative Activity and Induction of HLA-DR Antigen Expression

Günther Gastl, Christian Marth, Eva Leiter, Claus Gattringer, Inge Mayer, Günter Daxenbichler, Roswitha Flener, and Christoph Huber
Cancer Res 1985 45: 2957-2961. [Abstract] [PDF]  

Production of Antitumor T-Cells in Tumor-bearing Mice Treated with Tumor Vaccine and 6-Mercaptopurine

Tateshi Kataoka and Fujiko Oh-hashi
Cancer Res 1985 45: 2962-2966. [Abstract] [PDF]  

Augmentation of 5-Fluorouracil Cytotoxicity in Human Colon Cancer Cells by Dipyridamole

Jean L. Grem and Paul H. Fischer
Cancer Res 1985 45: 2967-2972. [Abstract] [PDF]  

Use of 3,4-Dichlorobenzenethiol as a Trapping Agent for Alkylating Intermediates during in Vitro Metabolism of Nitrosamines

Marilyn B. Kroeger-Koepke, Christopher J. Michejda, Peter P. Roller, and Larry K. Keefer
Cancer Res 1985 45: 2973-2975. [Abstract] [PDF]  

Effect of Growth and Sodium Butyrate on Brush Border Membrane-associated Hydrolases in Human Colorectal Cancer Cell Lines

Yong S. Chung, In S. Song, Roger H. Erickson, Marvin H. Sleisenger, and Young S. Kim
Cancer Res 1985 45: 2976-2982. [Abstract] [PDF]  

Treatment of Murine Intraperitoneal Ovarian Ascitic Tumor with Hematoporphyrin Derivative and Laser Light

Z. Tochner, J. B. Mitchell, F. S. Harrington, P. Smith, D. T. Russo, and A. Russo
Cancer Res 1985 45: 2983-2987. [Abstract] [PDF]  

Potential Antiglioma Activity of 9-Hydroxy-2-N-methylellipticine as Determined by Pharmacological and Human Tumor Clonogenic Cell Studies

Francis Ali-Osman, Mark L. Rosenblum, Donald D. Giannini, and Victor A. Levin
Cancer Res 1985 45: 2988-2992. [Abstract] [PDF]  

Alterations in the Activity and Isozymic Profile of Human Phosphofructokinase during Malignant Transformation in Vivo and in Vitro: Transformation- and Progression-linked Discriminants of Malignancy

Shobhana Vora, James P. Halper, and Daniel M. Knowles
Cancer Res 1985 45: 2993-3001. [Abstract] [PDF]  

Reduced Drug Accumulation in Multiply Drug-resistant Human KB Carcinoma Cell Lines

Antonio Fojo, Shin-ichi Akiyama, Michael M. Gottesman, and Ira Pastan
Cancer Res 1985 45: 3002-3007. [Abstract] [PDF]  

Experimental Antitumor Activity against Murine Tumor Model Systems of 8-Carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (Mitozolomide), a Novel Broad-Spectrum Agent

John A. Hickman, Malcolm F. G. Stevens, Neil W. Gibson, Simon P. Langdon, Christian Fizames, François Lavelle, Ghanem Atassi, Edward Lunt, and Robert M. Tilson
Cancer Res 1985 45: 3008-3013. [Abstract] [PDF]  

Flow Cytometric Analysis of Heterogeneity in Blood Group-related Antigen Expression in a Human Urinary Bladder Carcinoma Cell Line, 647V

John S. Coon, James R. Watkins, Bendicht U. Pauli, and Ronald S. Weinstein
Cancer Res 1985 45: 3014-3021. [Abstract] [PDF]  

Selective Effects by Valinomycin on Cytotoxicity and Cell Cycle Arrest of Transformed versus Nontransformed Rodent Fibroblasts in Vitro

Beate Kleuser, Hubert Rieter, and Gerold Adam
Cancer Res 1985 45: 3022-3028. [Abstract] [PDF]  

Superoxide Dismutase Levels in Chinese Hamster Ovary Cells and Ovarian Carcinoma Cells after Hyperthermia or Exposure to Cycloheximide

Dean P. Loven, Dennis B. Leeper, and Larry W. Oberley
Cancer Res 1985 45: 3029-3033. [Abstract] [PDF]  

Folate Analogues as Substrates of Mammalian Folylpolyglutamate Synthetase

Margot M. J. Schoo, Zdenek B. Pristupa, Philip J. Vickers, and K. Gray Scrimgeour
Cancer Res 1985 45: 3034-3041. [Abstract] [PDF]  

Estrous Cycle Modification of Rat Mammary Tumor Induction by a Single Dose of N-Methyl-N-nitrosourea

Thomas A. Ratko and Craig W. Beattie
Cancer Res 1985 45: 3042-3047. [Abstract] [PDF]  

Effects of Pyrimidine Antagonists on Sialic Acid Regeneration in HL-60 Cells

Alexander A. Hindenburg, Robert N. Taub, Steven Grant, George Chang, and Michael A. Baker
Cancer Res 1985 45: 3048-3052. [Abstract] [PDF]  

Biological and Biophysical Properties of the Tumor-localizing Component of Hematoporphyrin Derivative

David Kessel and May-Ling Cheng
Cancer Res 1985 45: 3053-3057. [Abstract] [PDF]  

Distribution of a New B-Cell-associated Surface Antigen (BL7) Detected by a Monoclonal Antibody in Human Leukemic Disorders

Ayad Al-Katib, Chang-Yi Wang, and Benjamin Koziner
Cancer Res 1985 45: 3058-3063. [Abstract] [PDF]  

Heterogeneity of X-Ray Cytotoxicity in Proliferating and Quiescent Murine Mammary Carcinoma Cells

C. Anne Wallen, David N. Ridinger, and Lyle A. Dethlefsen
Cancer Res 1985 45: 3064-3069. [Abstract] [PDF]  

Inhibition of 1-ß-D-Arabinofuranosylcytosine Transport and Net Accumulation by Teniposide and Etoposide in Ehrlich Ascites Cells and Human Leukemic Blasts

J. Courtland White, Leigh H. Hines, and James P. Rathmell
Cancer Res 1985 45: 3070-3075. [Abstract] [PDF]  

Hyperthermia and Human Leukocyte Functions: DNA, RNA, and Total Protein Synthesis after Exposure to <41° or >42.5° Hyperthermia

Norbert J. Roberts, Jr., Shin-Tsu Lu, and Sol M. Michaelson
Cancer Res 1985 45: 3076-3082. [Abstract] [PDF]  

Evidence for a Novel Pituitary Factor That Potentiates the Mitogenic Effect of Estrogen in Human Breast Cancer Cells

Thomas C. Dembinski, Clement K. H. Leung, and Robert P. C. Shiu
Cancer Res 1985 45: 3083-3089. [Abstract] [PDF]  

Distinct Differentiation-inducing Activities of -Interferon and Cytokine Factors Acting on the Human Promyelocytic Leukemia Cell Line HL-60

Paul E. Harris, Peter Ralph, Janice Gabrilove, Karl Welte, Rashida Karmali, and Malcolm A. S. Moore
Cancer Res 1985 45: 3090-3095. [Abstract] [PDF]  

Further Characterization of the DNA Adducts Formed by Electrophilic Esters of the Hepatocarcinogens 1'-Hydroxysafrole and 1'-Hydroxyestragole in Vitro and in Mouse Liver in Vivo, Including New Adducts at C-8 and N-7 of Guanine Residues

Roger W. Wiseman, Timothy R. Fennell, James A. Miller, and Elizabeth C. Miller
Cancer Res 1985 45: 3096-3105. [Abstract] [PDF]  

Single- and Double-Strand DNA Breakage and Repair in Human Lung Adenocarcinoma Cells Exposed to Etoposide and Teniposide

Byron H. Long, Steven T. Musial, and Michael G. Brattain
Cancer Res 1985 45: 3106-3112. [Abstract] [PDF]  

S1-Phase Cells of the Leukemic Cell Cycle Sensitive to 1-ß-D-Arabinofuranosylcytosine at a High-Dose Level

L. A. Smets and J. Homan-Blok
Cancer Res 1985 45: 3113-3117. [Abstract] [PDF]  

Synergism and Antagonism in the Effects of 1,25-Dihydroxyvitamin D₃, Retinoic Acid, Dexamethasone, and a Tumor-promoting Phorbol Ester on the Functional Capability of P388D1 Cells: Phagocytosis and Transglutaminase Activity

Rachel Goldman
Cancer Res 1985 45: 3118-3124. [Abstract] [PDF]  

Genotoxicity of a Variety of Pyrrolizidine Alkaloids in the Hepatocyte Primary Culture-DNA Repair Test Using Rat, Mouse, and Hamster Hepatocytes

Hideki Mori, Shigeyuki Sugie, Naoki Yoshimi, Yoshihisa Asada, Tsutomu Furuya, and Gary M. Williams
Cancer Res 1985 45: 3125-3129. [Abstract] [PDF]  

Suppression of Tumor Promoter-induced Chemiluminescence in Mouse Epidermal Cells by Several Inhibitors of Arachidonic Acid Metabolism

Susan M. Fischer and Laurel M. Adams
Cancer Res 1985 45: 3130-3136. [Abstract] [PDF]  

Effect of Heterogeneity of Carcinoembryonic Antigen on Liver Cell Membrane Binding and Its Kinetics of Removal from Circulation

R. A. Byrn, P. Medrek, P. Thomas, R. W. Jeanloz, and N. Zamcheck
Cancer Res 1985 45: 3137-3142. [Abstract] [PDF]  

Correlations between Intercalator-induced DNA Strand Breaks and Sister Chromatid Exchanges, Mutations, and Cytotoxicity in Chinese Hamster Cells

Yves Pommier, Leonard A. Zwelling, Chien-Song Kao-Shan, Jacqueline Whang-Peng, and Matthews O. Bradley
Cancer Res 1985 45: 3143-3149. [Abstract] [PDF]  

Effects of Combined Treatments of cis-Diamminedichloroplatinum(II), 5-Fluorouracil, and X-Rays on Growth of Human Cancer Nodules Maintained in Continuous Organotypic Culture

R. Beaupain and C. Dionet
Cancer Res 1985 45: 3150-3154. [Abstract] [PDF]  

Defective Facilitated Diffusion of Nucleosides, a Primary Mechanism of Resistance to 5-Fluoro-2'-deoxyuridine in the HCT-8 Human Carcinoma Line

Alberto F. Sobrero, Robyn D. Moir, Joseph R. Bertino, and Robert E. Handschumacher
Cancer Res 1985 45: 3155-3160. [Abstract] [PDF]  

Highly Selective Drug Combinations for Human Colon Cancer Cells Resistant in Vitro to 5-Fluoro-2'-deoxyuridine

Alberto F. Sobrero, Robert E. Handschumacher, and Joseph R. Bertino
Cancer Res 1985 45: 3161-3163. [Abstract] [PDF]  

Biochemical Characterization of 1-Butanol-extracted Murine Tumor-specific Transplantation Antigens

Stephen J. LeGrue, Neal R. Pellis, Lee B. Riley, and Barry D. Kahan
Cancer Res 1985 45: 3164-3172. [Abstract] [PDF]  

Role of Interleukin 2 and a Serum Suppressive Factor on the Induction of Activated Killer Cells Cytotoxic for Autologous Human Melanoma Cells

Kyogo Itoh, Arabella B. Tilden, and Charles M. Balch
Cancer Res 1985 45: 3173-3178. [Abstract] [PDF]  

Specificity and Inducibility of the Metabolic Reduction of Chromium(VI) Mutagenicity by Subcellular Fractions of Rat Tissues

Fernando Luigi Petrilli, Anna Camoirano, Carlo Bennicelli, Patrizia Zanacchi, Marina Astengo, and Silvio De Flora
Cancer Res 1985 45: 3179-3187. [Abstract] [PDF]  

Prominent Role of DT-Diaphorase as a Cellular Mechanism Reducing Chromium(VI) and Reverting Its Mutagenicity

Silvio De Flora, Alessandro Morelli, Cristina Basso, Marco Romano, Domizio Serra, and Antonio De Flora
Cancer Res 1985 45: 3188-3196. [Abstract] [PDF]  

DNA Alkali-labile Sites Induced by Incorporation of 5-Aza-2'-deoxycytidine into DNA of Mouse Leukemia L1210 Cells

Maurizio D'Incalci, Joseph M. Covey, Daniel S. Zaharko, and Kurt W. Kohn
Cancer Res 1985 45: 3197-3202. [Abstract] [PDF]  

Effect of 5-Hydroxytryptamine on Tissue Blood Flow and Microwave Heating of Rat Tumors

Shashi Shrivastav, William T. Joines, and Randy L. Jirtle
Cancer Res 1985 45: 3203-3208. [Abstract] [PDF]  

Induction of Branchial (Gill) Neoplasms in the Medaka Fish (Oryzias latipes) by N-Methyl-N'-nitro-N-nitrosoguanidine

Mavis R. Brittelli, Hans H. C. Chen, and Carl F. Muska
Cancer Res 1985 45: 3209-3214. [Abstract] [PDF]  

Effect of Sodium Butyrate on -Fetoprotein Gene Expression in Rat Hepatoma Cells in Vitro

Jeffry R. Cook, Charles E. Schwartz, E. David Fausel, and Jen-Fu Chiu
Cancer Res 1985 45: 3215-3219. [Abstract] [PDF]  

Monoclonal Antibodies to Glycoproteins of Vinca Alkaloid-resistant Human Leukemic Cells

Mary K. Danks, Dennis W. Metzger, Richard A. Ashmun, and William T. Beck
Cancer Res 1985 45: 3220-3224. [Abstract] [PDF]  

Characterization of the Blood Lymphocyte Population in Cattle Infected with the Bovine Leukemia Virus

E. N. Esteban, R. M. Thorn, and J. F. Ferrer
Cancer Res 1985 45: 3225-3230. [Abstract] [PDF]  

An Amplified Immunoperoxidase Assay to Detect Bovine Leukemia Virus Expression: Development and Comparison with Other Assays

E. N. Esteban, R. M. Thorn, and J. F. Ferrer
Cancer Res 1985 45: 3231-3235. [Abstract] [PDF]  

Altered Actin Cytoskeletal Patterns in Two Premalignant Stages in Human Colon Carcinoma Development

Eileen Friedman, Michael Verderame, Martin Lipkin, and Robert Pollack
Cancer Res 1985 45: 3236-3242. [Abstract] [PDF]  

Cell-free System Studies on the Phosphorylation of the 17,000–20,000 Dalton Protein Induced by Phorbol Ester in Human Leukemic Cells and Evidence for a Similar Event in Virally Transformed Murine Fibroblasts

Nili Feuerstein, Masakatsu Nishikawa, and Herbert L. Cooper
Cancer Res 1985 45: 3243-3251. [Abstract] [PDF]  

Histological Types of Carcinoma of the Uterine Cervix and the Detectability of Human Papillomavirus DNA

Michio Fukushima, Takashi Okagaki, Leo B. Twiggs, Barbara A. Clark, Karen R. Zachow, Ronald S. Ostrow, and Anthony J. Faras
Cancer Res 1985 45: 3252-3255. [Abstract] [PDF]  

Expression of Neoplasia-related Proteins of Chemically Transformed HuT Fibroblasts in Human Osteosarcoma HOS Fibroblasts and Modulation of Actin Expression upon Elevation of Tumorigenic Potential

David Goldstein and John Leavitt
Cancer Res 1985 45: 3256-3261. [Abstract] [PDF]  

Oncogene Activation in Human Myeloid Leukemia

Johannes W. G. Janssen, Ada C. M. Steenvoorden, John G. Collard, and Roel Nusse
Cancer Res 1985 45: 3262-3267. [Abstract] [PDF]  

Evidence for Homology of Normal and Neoplastic Human Placental Alkaline Phosphatases as Determined by Monoclonal Antibodies to the Cancer-associated Enzyme

Ronald Jemmerson, Nila Shah, and William H. Fishman
Cancer Res 1985 45: 3268-3273. [Abstract] [PDF]  

Monoclonal Antibodies to Human Squamous Cell Carcinoma of the Lung and Their Application to Tumor Diagnosis

Seishi Kyoizumi, Mitoshi Akiyama, Nobuoki Kouno, Kyoko Kobuke, Masayuki Hakoda, Stephen L. Jones, and Michio Yamakido
Cancer Res 1985 45: 3274-3281. [Abstract] [PDF]  

Suppression of Natural Killer and Lymphocyte Functions Associated with Carcinogen-induced Premalignant Hyperplastic Nodules in Rat Liver

Richard W. Leu, Tom R. Norton, Mary J. Herriott, David P. Ringer, and Robert J. Kearns
Cancer Res 1985 45: 3282-3287. [Abstract] [PDF]  

Effect of Prolonged Insulin Treatment on Carcinoma Formation in Mice

Aurel P. Lupulescu
Cancer Res 1985 45: 3288-3295. [Abstract] [PDF]  

Adriamycin-enhanced Membrane Lipid Peroxidation in Isolated Rat Nuclei

Edward G. Mimnaugh, Katherine A. Kennedy, Michael A. Trush, and Birandra K. Sinha
Cancer Res 1985 45: 3296-3304. [Abstract] [PDF]  

Protective Effect of Cholesterol on Friend Leukemic Cells against Photosensitization by Hematoporphyrin Derivative

S. Salzberg, F. Lejbkowicz, B. Ehrenberg, and Z. Malik
Cancer Res 1985 45: 3305-3310. [Abstract] [PDF]  

Effects of Vitamin A and Dexamethasone on Collagen Degradation in Mouse Mammary Adenocarcinoma

Shizuko Takahashi and Luis Biempica
Cancer Res 1985 45: 3311-3321. [Abstract] [PDF]  

Changes in Stem Cell Populations of Rat Tracheal Epithelial Cell Cultures at an Early Stage in Neoplastic Progression

David Thomassen, J. Carl Barrett, Diane K. Beeman, and Paul Nettesheim
Cancer Res 1985 45: 3322-3331. [Abstract] [PDF]  

Isolation of Retinoic Acid-resistant Clones from Human Breast Cancer Cell Line MCF-7 with Altered Activity of Cellular Retinoic Acid-binding Protein

Hitoshi Ueda, Mayumi Ono, Yoshiaki Hagino, and Michihiko Kuwano
Cancer Res 1985 45: 3332-3338. [Abstract] [PDF]  

Defective Control of Terminal Differentiation and Its Role in Carcinogenesis in the 3T3 T Proadipocyte Stem Cell Line

Marjorie L. Wier and Robert E. Scott
Cancer Res 1985 45: 3339-3346. [Abstract] [PDF]  

Clinical and Epidemiological Investigations:

Limited Impact of Total Parenteral Nutrition on Nutritional Status during Treatment for Small Cell Lung Cancer

William K. Evans, Robert Makuch, Gerald H. Clamon, Ronald Feld, Roy S. Weiner, Edgar Moran, Ronald Blum, Frances A. Shepherd, Khursheed N. Jeejeebhoy, and William D. DeWys
Cancer Res 1985 45: 3347-3353. [Abstract] [PDF]  

Sequential Infusions of Methotrexate and 5-Fluorouracil in Advanced Cancer: Pharmacology, Toxicity, and Response

C. Benz, M. DeGregorio, S. Saks, N. Sambol, W. Holleran, R. Ignoffo, B. Lewis, and E. Cadman
Cancer Res 1985 45: 3354-3358. [Abstract] [PDF]  

A Phase I and Pharmacokinetic Study of Dihydro-5-azacytidine (NSC 264880)

Gregory A. Curt, James A. Kelley, Robert L. Fine, Philipp N. Huguenin, Jeri S. Roth, Gerald Batist, Jean Jenkins, and Jerry M. Collins
Cancer Res 1985 45: 3359-3363. [Abstract] [PDF]  

Presence of Breast Cancer Antigens in Uninvolved Axillary Lymph Nodes

Fred J. Hendler and Diane House
Cancer Res 1985 45: 3364-3373. [Abstract] [PDF]  

Antigenicity of Human T-Cell Leukemia Virus-associated gp52: Greater Response in Leukemia Patients Compared to Healthy Donors Exposed to the Virus

Marjorie Robert-Guroff and Jeffrey W. Clark
Cancer Res 1985 45: 3374-3377. [Abstract] [PDF]  

Imaging with ¹³¹I-Labeled Monoclonal Antibodies to a High-Molecular-Weight Melanoma-associated Antigen in Patients with Melanoma: Efficacy of Whole Immunoglobulin and Its F(ab')₂ Fragments

G. L. Buraggi, L. Callegaro, G. Mariani, A. Turrin, N. Cascinelli, A. Attili, E. Bombardieri, G. Terno, G. Plassio, M. Dovis, N. Mazzuca, P. G. Natali, G. A. Scassellati, U. Rosa, and S. Ferrone
Cancer Res 1985 45: 3378-3387. [Abstract] [PDF]  

Unscheduled DNA Synthesis in Mononuclear Leukocytes from Patients with Colorectal Polyps

Ronald W. Pero, Marianne Ritchie, Sidney J. Winawer, Melvin M. Markowitz, and Daniel G. Miller
Cancer Res 1985 45: 3388-3391. [Abstract] [PDF]  

Flow Cytometric Detection of Aneuploidy in Colorectal Adenomas

Harry F. van den Ingh, Gerrit Griffioen, and Cornelis J. Cornelisse
Cancer Res 1985 45: 3392-3397. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: I. G. Kerr et al. Effect of Intravenous Dose and Schedule on Cerebrospinal Fluid Pharmacokinetics of 5-Fluorouracil in the Monkey. Cancer Res., 44: 4929–4932, 1984.

John E. Byfield and Cecil L. Hornbeck
Cancer Res 1985 45: 3398-3399. [PDF]  

Correspondence re: I. G. Kerr et al. Effect of Intravenous Dose and Schedule on Cerebrospinal Fluid Pharmacokinetics of 5-Fluorouracil in the Monkey. Cancer Res., 44: 4929–4932, 1984. — Reply

Jerry M. Collins and Ian G. Kerr
Cancer Res 1985 45: 3399 [PDF]  

Correspondence re: F. A. Schmid et al. Mutagenic and Chemotherapeutic Activity in L1210 Leukemia of Several Monofunctional Alkylating Agents. Cancer Res., 45: 40–44, 1985

Glynn P. Wheeler, Doris J. Adamson, and Joliet Webster
Cancer Res 1985 45: 3400-3402. [PDF]  

Correspondence re: F. A. Schmid et al. Mutagenic and Chemotherapeutic Activity in L1210 Leukemia of Several Monofunctional Alkylating Agents. Cancer Res., 45: 40–44, 1985 — Reply

Franz A. Schmid and Glenys M. Otter
Cancer Res 1985 45: 3402 [PDF]  

Articles:

Announcements

Cancer Res 1985 45: 3403-3404. [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.