Basic Sciences:

Derivatives of 5,6-Diphenylpyridazin-3-one: Synthetic Antimitotic Agents Which Interact with Plant and Mammalian Tubulin at a New Drug-binding Site

Janendra K. Batra, L. J. Powers, F. Dana Hess, and Ernest Hamel
Cancer Res 1986 46: 1889-1893. [Abstract] [PDF]  

Characterization of Alterations in Plasma Lipoprotein Lipid and Apoprotein Profiles Accompanying Hepatoma-induced Hyperlipidemia in Rats

Ronald W. Clark and Richard C. Crain
Cancer Res 1986 46: 1894-1903. [Abstract] [PDF]  

Use of Two MCF-7 Cell Variants to Evaluate the Growth Regulatory Potential of Estrogen-induced Products

Nancy E. Davidson, Diane A. Bronzert, Pierre Chambon, Edward P. Gelmann, and Marc E. Lippman
Cancer Res 1986 46: 1904-1908. [Abstract] [PDF]  

Protection from Procarbazine-induced Damage of Spermatogenesis in the Rat by Androgen

Julian I. Delic, Cynthia Bush, and Michael J. Peckham
Cancer Res 1986 46: 1909-1914. [Abstract] [PDF]  

Expression of Retroviral Sequences and Oncogenes in Murine Hepatocellular Tumors

Tommaso A. Dragani, Giacomo Manenti, Giuseppe Della Porta, Sebastiano Gattoni-Celli, and I. Bernard Weinstein
Cancer Res 1986 46: 1915-1919. [Abstract] [PDF]  

Heterogeneity in the Hormonal Responsiveness of Clones Derived from the 13762NF Rat Mammary Tumor

Joseph Geradts, James Richards, Marc Edery, Kevin Pang, Lisa Larson, and Satyabrata Nandi
Cancer Res 1986 46: 1920-1927. [Abstract] [PDF]  

Metastatic Behavior of Tumor Cells Isolated from Primary and Metastatic Human Colorectal Carcinomas Implanted into Different Sites in Nude Mice

Raffaella Giavazzi, Debora E. Campbell, J. M. Jessup, Karen Cleary, and Isaiah J. Fidler
Cancer Res 1986 46: 1928-1933. [Abstract] [PDF]  

Characterization of Acquired Epipodophyllotoxin Resistance in a Chinese Hamster Ovary Cell Line: Loss of Drug-stimulated DNA Cleavage Activity

Bonnie Glisson, Radhey Gupta, Sherin Smallwood-Kentro, and Warren Ross
Cancer Res 1986 46: 1934-1938. [Abstract] [PDF]  

Cross-Resistance to Intercalating Agents in an Epipodophyllotoxin-resistant Chinese Hamster Ovary Cell Line: Evidence for a Common Intracellular Target

Bonnie Glisson, Radhey Gupta, Paula Hodges, and Warren Ross
Cancer Res 1986 46: 1939-1942. [Abstract] [PDF]  

DNA Sequence Selectivity of Guanine-N7 Alkylation by Three Antitumor Chloroethylating Agents

John A. Hartley, Neil W. Gibson, Kurt W. Kohn, and William B. Mattes
Cancer Res 1986 46: 1943-1947. [Abstract] [PDF]  

A Distinctive Form of Human Chorionic Gonadotropin ß-Subunit-like Material Produced by Cervical Carcinoma Cells

Robert O. Hussa, Henry G. Fein, Roland A. Pattillo, Steven B. Nagelberg, Saul W. Rosen, Bruce D. Weintraub, Fulvio Perini, Raymond W. Ruddon, and Laurence A. Cole
Cancer Res 1986 46: 1948-1954. [Abstract] [PDF]  

Insulin and Epidermal Growth Factor Receptors in Rat Liver after Administration of the Hepatocarcinogen 2-Acetylaminofluorene: Ligand Binding and Autophosphorylation

David L. Hwang, Avraham Roitman, Brian I. Carr, Gegham Barseghian, and Arye Lev-Ran
Cancer Res 1986 46: 1955-1959. [Abstract] [PDF]  

Effect of Nocardia rubra Cell Wall Skeleton on Murine Interferon Production in Vitro

Shizue Izumi, Hirotsugu Ueda, Masakuni Okuhara, Hatsuo Aoki, and Yuichi Yamamura
Cancer Res 1986 46: 1960-1965. [Abstract] [PDF]  

Purification of Stable Protein Kinase C from Mouse Brain Cytosol by Specific Ligand Elution Using Fast Protein Liquid Chromatography

Arco Y. Jeng, Nancy A. Sharkey, and Peter M. Blumberg
Cancer Res 1986 46: 1966-1971. [Abstract] [PDF]  

Mechanism of Cytotoxicity of Anticancer Platinum Drugs: Evidence That cis-Diamminedichloroplatinum(II) and cis-Diammine-(1,1-cyclobutanedicarboxylato)platinum(II) Differ Only in the Kinetics of Their Interaction with DNA

Richard J. Knox, Frank Friedlos, David A. Lydall, and John J. Roberts
Cancer Res 1986 46: 1972-1979. [Abstract] [PDF]  

Invasion of Reconstituted Basement Membrane Matrix by Metastatic Human Tumor Cells

Randall H. Kramer, Klaus G. Bensch, and Johnson Wong
Cancer Res 1986 46: 1980-1989. [Abstract] [PDF]  

Elevated Amounts of a 7S Nuclear RNA with Sequence Homology to a Tumor Virus Promoter in Transformed and Tumorigenic Cells

Margarida O. Krause, Jolanta Kurz, Jane Lovely, and Paul MacPherson
Cancer Res 1986 46: 1990-1993. [Abstract] [PDF]  

Inhibition of Mouse Lung Tumor Development by Hyperoxia

R. C. Lindenschmidt, A. F. Tryka, and H. P. Witschi
Cancer Res 1986 46: 1994-2000. [Abstract] [PDF]  

Sequential Changes of Mouse Bladder Epithelium during Induction of Invasive Carcinomas by N-Butyl-N-(4-hydroxybutyl)nitrosamine

Mikinobu Ohtani, Tadao Kakizoe, Yasunori Nishio, Shigeaki Sato, Takashi Sugimura, Shoji Fukushima, and Tadao Niijima
Cancer Res 1986 46: 2001-2004. [Abstract] [PDF]  

Connective Tissue Degradation by Invasive Rat Bladder Carcinomas: Action of Nonspecific Proteinases on Collagenous Matrices

Bendicht U. Pauli, Charalampos Arsenis, Leslie H. Hohberger, and David E. Schwartz
Cancer Res 1986 46: 2005-2012. [Abstract] [PDF]  

Demonstration of Human Breast Carcinoma Cells in Cryosections and Primary Monolayer Cultures of Surgical Biopsies by Neotetrazolium Reductase Cytochemistry

O. W. Petersen and B. van Deurs
Cancer Res 1986 46: 2013-2020. [Abstract] [PDF]  

DNA Damage by Antitumor Acridines Mediated by Mammalian DNA Topoisomerase II

Thomas C. Rowe, Grace L. Chen, Yaw-Huei Hsiang, and Leroy F. Liu
Cancer Res 1986 46: 2021-2026. [Abstract] [PDF]  

Dynamics of Tumor Growth and Cellular Adaptation after Inoculation into Nude Mice of Varying Numbers of Transformed 3T3 Cells and of Readaptation to Culture of the Tumor Cells

Harry Rubin, Berbie M. Chu, and Paul Arnstein
Cancer Res 1986 46: 2027-2034. [Abstract] [PDF]  

Bladder Cancer Xenografts: A Model of Tumor Cell Heterogeneity

Pamela J. Russell, Derek Raghavan, Patricia Gregory, Jeanette Philips, Edward J. Wills, Margaret Jelbart, Jane Wass, Rosemary A. Zbroja, and Paul C. Vincent
Cancer Res 1986 46: 2035-2040. [Abstract] [PDF]  

Detection of Mutant Diphtheria Toxin-resistant Chinese Hamster Lung Cells in Situ by Autoradiography

Hiromi Sakamoto, Masaaki Terada, and Takashi Sugimura
Cancer Res 1986 46: 2041-2044. [Abstract] [PDF]  

Chromosomal Radiosensitivity during the G₂ Cell Cycle Period and Cytopathology of Human Normal x Tumor Cell Hybrids

Katherine K. Sanford, Ram Parshad, Eric J. Stanbridge, John K. Frost, Gary M. Jones, Joyce E. Wilkinson, and Robert E. Tarone
Cancer Res 1986 46: 2045-2049. [Abstract] [PDF]  

Comparison of Amplified and Unamplified c-myc Gene Structure and Expression in Human Small Cell Lung Carcinoma Cell Lines

Eric J. Seifter, Edward A. Sausville, and Jim Battey
Cancer Res 1986 46: 2050-2055. [Abstract] [PDF]  

Effector Mechanism in Antitumor Activity of Monoclonal Antibodies Produced against an Ascitic Mouse Mammary Tumor

Masao Seto, Toshitada Takahashi, Sohko Nakamura, Masahiko Saito, Takeshi Hara, and Yasuaki Nishizuka
Cancer Res 1986 46: 2056-2061. [Abstract] [PDF]  

Uracil-induced Urolithiasis and the Development of Reversible Papillomatosis in the Urinary Bladder of F344 Rats

Tomoyuki Shirai, Etsuo Ikawa, Shoji Fukushima, Tsuneo Masui, and Nobuyuki Ito
Cancer Res 1986 46: 2062-2067. [Abstract] [PDF]  

Reversible Inhibition of Normal Human Prokeratinocyte Proliferation by Type ß Transforming Growth Factor-Growth Inhibitor in Serum-free Medium

Gary D. Shipley, Mark R. Pittelkow, John J. Wille, Jr., Robert E. Scott, and Harold L. Moses
Cancer Res 1986 46: 2068-2071. [Abstract] [PDF]  

Dye-mediated Photosensitization of Murine Neuroblastoma Cells

Fritz Sieber and Maya Sieber-Blum
Cancer Res 1986 46: 2072-2076. [Abstract] [PDF]  

Cytotoxic Murine Monoclonal Antibody LAM8 with Specificity for Human Small Cell Carcinoma of the Lung

Rolf A. Stahel, Carl J. O'Hara, Mack Mabry, Robert Waibel, Kert Sabbath, Johnathan A. Speak, and Samuel D. Bernal
Cancer Res 1986 46: 2077-2084. [Abstract] [PDF]  

Rescue of a Biologically Active Epstein-Barr Virus from Nonproducer Cells

Toru Takimoto, Hiroshi Sato, Hisashi Ogura, and Ronald Glaser
Cancer Res 1986 46: 2085-2087. [Abstract] [PDF]  

Decreased Numbers of Spindle and Cytoplasmic Microtubules in Hamster Embryo Cells Treated with a Carcinogen, Diethylstilbestrol

Robert W. Tucker and J. Carl Barrett
Cancer Res 1986 46: 2088-2095. [Abstract] [PDF]  

Mammary Tumorigenesis and Tumor Morphology in Four C3H Sublines with or without Exogenous Mammary Tumor Virus

Jan Vaage, Gilbert H. Smith, Bonnie B. Asch, and Yoshio Teramoto
Cancer Res 1986 46: 2096-2100. [Abstract] [PDF]  

Clinical and Epidemiological Investigations:

Interleukin-2 or Autologous Lymphokine-activated Killer Cell Treatment of Malignant Glioma: Phase I Trial

Steven K. Jacobs, Debra J. Wilson, Paul L. Kornblith, and Elizabeth A. Grimm
Cancer Res 1986 46: 2101-2104. [Abstract] [PDF]  

Evidence for the Importance of 5'-Deoxy-5-fluorouridine Catabolism in Humans from ¹⁹F Nuclear Magnetic Resonance Spectrometry

Marie C. Malet-Martino, Jean-Pierre Armand, André Lopez, Jean Bernadou, Jean-Pierre Béteille, Maryse Bon, and Robert Martino
Cancer Res 1986 46: 2105-2112. [Abstract] [PDF]  

Motor Exhaust-related Occupations and Bladder Cancer

Debra T. Silverman, Robert N. Hoover, Thomas J. Mason, and G. Marie Swanson
Cancer Res 1986 46: 2113-2116. [Abstract] [PDF]  

Estrogen and Progesterone Receptors in Breast Cancer among Women of Different Racial Groups

Rosemary J. Pegoraro, Vijayluxmi Karnan, Dharamraj Nirmul, and Septimus M. Joubert
Cancer Res 1986 46: 2117-2120. [Abstract] [PDF]  

Monoclonal Antibody-defined Phenotypes of Regional Lymph Node and Peripheral Blood Lymphocyte Subpopulations in Early Breast Cancer

Blaine A. Morton, William G. Ramey, Hermosa Paderon, and Robert E. Miller
Cancer Res 1986 46: 2121-2126. [Abstract] [PDF]  

Antibody Development to Viral and Allogeneic Tumor Cell-associated Antigens in Patients with Malignant Melanoma and Ovarian Carcinoma Treated with Lysates of Virus-infected Tumor Cells

Howard E. Savage, Roger D. Rossen, Evan M. Hersh, Ralph S. Freedman, James M. Bowen, and Carl Plager
Cancer Res 1986 46: 2127-2133. [Abstract] [PDF]  

A Cytogenetic Study of Familial Medullary Carcinoma of the Thyroid

Doris H. Wurster-Hill, Walter W. Noll, Laddawan Y. Bircher, John Devlin, and Edward Schultz
Cancer Res 1986 46: 2134-2138. [Abstract] [PDF]  

Cytogenetic Studies of Tumor Tissue from Patients with Nonfamilial Renal Cell Carcinoma

Mitsuaki A. Yoshida, Kazuma Ohyashiki, Hisako Ochi, Zenon Gibas, J. Edson Pontes, George R. Prout, Jr., Robert Huben, and Avery A. Sandberg
Cancer Res 1986 46: 2139-2147. [Abstract] [PDF]  

Phase I Study of Ethylenediamine Platinum(II) Malonate (NSC 146 068), a Second Generation Platinum Analogue

Benjamin Winograd, Jan B. Vermorken, Wim W. ten Bokkel Huinink, Godelaine Simonetti, Helen E. Gall, M. K. Tish Knobf, Wim J. F. van der Vijgh, J. Gordon McVie, and Herbert M. Pinedo
Cancer Res 1986 46: 2148-2151. [Abstract] [PDF]  

Anomalous Adenosine Cyclic 3':5'-Monophosphate Responses to Glucagon in Patients with Hepatocellular Carcinoma

K. K. Pun, P. W. M. Ho, and R. T. T. Yeung
Cancer Res 1986 46: 2152-2154. [Abstract] [PDF]  

Establishment in Long Term Culture of Megakaryocytic Leukemia Cells (EST-IU) from the Marrow of a Patient with Leukemia and a Mediastinal Germ Cell Neoplasm

George W. Sledge, Jr., Michael Glant, Jan Jansen, Nyla A. Heerema, Bruce J. Roth, Michael Goheen, and Ronald Hoffman
Cancer Res 1986 46: 2155-2159. [Abstract] [PDF]  

Induction of 2',5'-Oligoadenylate Synthetase and Blast Transformation in Primary Chronic Lymphocytic Leukemia Cells following Exposure to Interferon in Vitro

Leif Östlund, Stefan Einhorn, and Karl-Henric Robèrt
Cancer Res 1986 46: 2160-2163. [Abstract] [PDF]  

Antigen Expression in Normal and Neoplastic Colonic Mucosa: Three Tissue-specific Antigens Using Monoclonal Antibodies to Isolated Colonic Glands

Norman R. Hughes, Ronald S. Walls, Ronald C. Newland, and John E. Payne
Cancer Res 1986 46: 2164-2171. [Abstract] [PDF]  

Induction of Features Characteristic of Hairy Cell Leukemia in Chronic Lymphocytic Leukemia and Prolymphocytic Leukemia Cells

H. W. Löms Ziegler-Heitbrock, Reinhold Munker, Bernd Dörken, Gerhard Gaedicke, and Eckhard Thiel
Cancer Res 1986 46: 2172-2178. [Abstract] [PDF]  

Biochemical Changes Induced in Hairy-Cell Leukemia following Treatment with the Adenosine Deaminase Inhibitor 2'-Deoxycoformycin

James B. Johnston, Asher Begleiter, Linda Pugh, Marsha K. Leith, John A. Wilkins, Douglas J. Cavers, and Lyonel G. Israels
Cancer Res 1986 46: 2179-2184. [Abstract] [PDF]  

Presence of Human Papillomavirus Type 16 Related Sequences in Verrucous Carcinoma of the Larynx

Janet L. Brandsma, Bettie M. Steinberg, Allan L. Abramson, and Barbara Winkler
Cancer Res 1986 46: 2185-2188. [Abstract] [PDF]  

Letter to the Editor:

Role of Murine Tumor Models in Cancer Treatment Research

Daniel S. Martin, M. Earl Balis, Bernard Fisher, Emil Frei, Emil J Freireich, Gloria H. Heppner, James F. Holland, Janet A. Houghton, Peter J. Houghton, Randall K. Johnson, Arnold Mittelman, Youcef Rustum, Robert C. Sawyer, Franz A. Schmid, Robert L. Stolfi, and Charles W. Young
Cancer Res 1986 46: 2189-2192. [Abstract] [PDF]  

Meeting Report:

Fifth Annual Sapporo Cancer Seminar: Monoclonal Antibodies—Progress In Cancer Immunobiology and Clinical Application

Ralph A. Reisfeld, Mark I. Greene, and Akira Yachi
Cancer Res 1986 46: 2193-2196. [PDF]  

Articles:

Special Announcement

Cancer Res 1986 46: 2197 [PDF]  

Announcements

Cancer Res 1986 46: 2197-2199. [PDF]  

Recent Deaths

Cancer Res 1986 46: 2199 [PDF]  

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