REVIEWS:

Biochemistry and Clinical Activity of N-(Phosphonacetyl)-L-aspartate: A Review

Jean L. Grem, Susan A. King, Peter J. O'Dwyer, and Brian Leyland-Jones
Cancer Res 1988 48: 4441-4454. [PDF]  

Basic Sciences:

Influence of Neighboring Base Sequence on the Distribution and Repair of N-Ethyl-N-nitrosourea-induced Lesions in Escherichia coli

Philip A. Burns, Alasdair J. E. Gordon, Kathy Kunsmann, and Barry W. Glickman
Cancer Res 1988 48: 4455-4458. [Abstract] [PDF]  

Activated ras Oncogenes in Human Thyroid Cancers

Nick R. Lemoine, Edward S. Mayall, Fiona S. Wyllie, Christine J. Farr, David Hughes, Rose Anne Padua, Valerie Thurston, E. Dilwyn Williams, and David Wynford-Thomas
Cancer Res 1988 48: 4459-4463. [Abstract] [PDF]  

Formation of S-Adenosylethionine in Liver of Rats Chronically Fed with DL-Ethionine

Zbynek Brada, Ingrid Hrstka, and Stefan Bulba
Cancer Res 1988 48: 4464-4468. [Abstract] [PDF]  

Novel Synthesis and in Vitro Characterization of Disulfide-linked Ricin-Monoclonal Antibody Conjugates Devoid of Galactose Binding Activity

Geoffrey A. Pietersz, Jerry Kanellos, and Ian F. C. McKenzie
Cancer Res 1988 48: 4469-4476. [Abstract] [PDF]  

Properties of Verapamil-hypersensitive Multidrug-resistant Chinese Hamster Ovary Cells

J. Roger Warr, Michael Anderson, and Jill Fergusson
Cancer Res 1988 48: 4477-4483. [Abstract] [PDF]  

Mechanism of cis-Diamminedichloroplatinum(II)-induced Cytotoxicity: Role of G₂ Arrest and DNA Double-Strand Breaks

Christine M. Sorenson and Alan Eastman
Cancer Res 1988 48: 4484-4488. [Abstract] [PDF]  

Differences in DNA Alkylation Products Formed in Sensitive and Resistant Human Glioma Cells Treated with N-(2-Chloroethyl)-N-nitrosourea

William J. Bodell, Kouichi Tokuda, and David B. Ludlum
Cancer Res 1988 48: 4489-4492. [Abstract] [PDF]  

Effect of Endogenous Glutathione, Superoxide Dismutases, Catalase, and Glutathione Peroxidase on Adriamycin Tolerance of Chinese Hamster Ovary Cells

Hiskias G. Keizer, Johan van Rijn, Herbert M. Pinedo, and Hans Joenje
Cancer Res 1988 48: 4493-4497. [Abstract] [PDF]  

Expression of the Platelet-derived Growth Factor 1 and 2 Genes in Human Myeloid Cell Lines and Monocytes

E. Sariban and D. Kufe
Cancer Res 1988 48: 4498-4502. [Abstract] [PDF]  

Metallothionein Induction and Deinduction in Human Prostatic Carcinoma Cells: Relationship with Resistance and Sensitivity to Adriamycin

Mukta M. Webber, S. M. Maseehur Rehman, and Gordon T. James
Cancer Res 1988 48: 4503-4508. [Abstract] [PDF]  

Increased Cytotoxicity and Reversal of Resistance to cis-Diamminedichloroplatinum(II) with Entrapment of cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum(II) in Multilamellar Lipid Vesicles

Roman Perez-Soler, Li Y. Yang, Benjamin Drewinko, Julio Lauterzstain, and Abdul R. Khokhar
Cancer Res 1988 48: 4509-4512. [Abstract] [PDF]  

Specificity of Rabbit Cytochrome P-450 Isozymes Involved in the Metabolic Activation of the Food Derived Mutagen 2-Amino-3-methylimidazo[4,5-] quinoline

Michael E. McManus, Wendy Burgess, Elizabeth Snyderwine, and Ieva Stupans
Cancer Res 1988 48: 4513-4519. [Abstract] [PDF]  

Plasminogen Activator Profiles in Neoplastic Tissues of the Human Colon

Paul A. F. de Bruin, Gerrit Griffioen, Hein W. Verspaget, Jan H. Verheijen, Gerard Dooijewaard, Harry F. van den Ingh, and Cornelis B. H. W. Lamers
Cancer Res 1988 48: 4520-4524. [Abstract] [PDF]  

Quantitative Transplantation Assays of Spontaneous Tumors of the C3H Mouse as Allografts in Athymic NCr/Sed-nu/nu Nude Mice and Isografts in C3Hf/Sed Mice

Herman D. Suit, Robert S. Sedlacek, and Anthony Zietman
Cancer Res 1988 48: 4525-4528. [Abstract] [PDF]  

Effects of Folate Deficiency on the Metastatic Potential of Murine Melanoma Cells

Richard F. Branda, John J. McCormack, Carol A. Perlmutter, Linda A. Mathews, and Steven H. Robison
Cancer Res 1988 48: 4529-4534. [Abstract] [PDF]  

Radiosensitivities of Ten Apparently Normal Human Diploid Fibroblast Strains to Cell Killing, G₂-Phase Chromosomal Aberrations, and Cell Cycle Delay

Hatsumi Nagasawa and John B. Little
Cancer Res 1988 48: 4535-4538. [Abstract] [PDF]  

Differential Cell Photosensitivity following Porphyrin Photodynamic Therapy

Charles J. Gomer, Natalie Rucker, and A. Linn Murphree
Cancer Res 1988 48: 4539-4542. [Abstract] [PDF]  

Monoclonal Antibody PR92 with Restricted Specificity for Tumor-associated Antigen of Prostate and Breast Carcinoma

Yung D. Kim, Deborah Y. Robinson, and Joseph T. Tomita
Cancer Res 1988 48: 4543-4548. [Abstract] [PDF]  

Development and Characterization of a Rat Model for Locally Recurring Mammary Tumors: Sensitivities to 5-Fluoro-2'-deoxyuridine, Adriamycin, and X-Irradiation

Danny R. Welch, Paul A. Aeed, and Jaime Estrada
Cancer Res 1988 48: 4549-4554. [Abstract] [PDF]  

Epidermal Growth Factor Gene Expression in Human Breast Cancer Cells: Regulation of Expression by Progestins

Leigh C. Murphy, Liam J. Murphy, Don Dubik, Graeme I. Bell, and Robert P. C. Shiu
Cancer Res 1988 48: 4555-4560. [Abstract] [PDF]  

Effect of Whole-Body Hyperthermia and Cyclophosphamide on Natural Killer Cell Activity in Murine Erythroleukemia

Rong-Nian Shen, Ned B. Hornback, Homayoon Shidnia, Li Lu, Hal E. Broxmeyer, and Zacharie Brahmi
Cancer Res 1988 48: 4561-4563. [Abstract] [PDF]  

Analysis of DNA Sequences in Forty-Year-Old Paraffin-embedded Thin-Tissue Sections: A Bridge between Molecular Biology and Classical Histology

Darryl Shibata, W. John Martin, and Norman Arnheim
Cancer Res 1988 48: 4564-4566. [Abstract] [PDF]  

Cachectin/Tumor Necrosis Factor: A Possible Mediator of Cancer Anorexia in the Rat

Mark C. Stovroff, Douglas L. Fraker, John A. Swedenborg, and Jeffrey A. Norton
Cancer Res 1988 48: 4567-4572. [Abstract] [PDF]  

Removal of Breast Cancer Cells by Soybean Agglutinin in an Experimental Model for Purging Human Marrow

Shoshana Morecki, Shlomo Margel, and Shimon Slavin
Cancer Res 1988 48: 4573-4577. [Abstract] [PDF]  

Resistance of HeLa Cell Mitochondrial DNA to Mutagenesis by Chemical Carcinogens

Shiro Mita, Raymond J. Monnat, Jr., and Lawrence A. Loeb
Cancer Res 1988 48: 4578-4583. [Abstract] [PDF]  

Increased Adriamycin Levels in Hepatic Implants of Rabbit Vx-2 Carcinoma from Regional Infusion

John A. Ridge, Charles Collin, James R. Bading, Counce Hancock, Peter S. Conti, John M. Daly, and John H. Raaf
Cancer Res 1988 48: 4584-4587. [Abstract] [PDF]  

Generation and Characterization of B72.3 Second Generation Monoclonal Antibodies Reactive with the Tumor-associated Glycoprotein 72 Antigen

Raffaella Muraro, Masahide Kuroki, David Wunderlich, Diane J. Poole, David Colcher, Ann Thor, John W. Greiner, Jean F. Simpson, Alfredo Molinolo, Philip Noguchi, and Jeffrey Schlom
Cancer Res 1988 48: 4588-4596. [Abstract] [PDF]  

Radioimmunolocalization of Human Carcinoma Xenografts with B72.3 Second Generation Monoclonal Antibodies

David Colcher, Maria Filomena Minelli, Mario Roselli, Raffaella Muraro, Diane Simpson-Milenic, and Jeffrey Schlom
Cancer Res 1988 48: 4597-4603. [Abstract] [PDF]  

Metalloporphyrin Enhancement of Magnetic Resonance Imaging of Human Tumor Xenografts in Nude Mice

Philip Furmanski and Clifford Longley
Cancer Res 1988 48: 4604-4610. [Abstract] [PDF]  

Apparent Stronger Expression in the Human Adrenal Cortex than in the Human Adrenal Medulla of M_r 170,000–180,000 P-Glycoprotein

Isamu Sugawara, Masao Nakahama, Hirofumi Hamada, Takashi Tsuruo, and Shigeo Mori
Cancer Res 1988 48: 4611-4614. [Abstract] [PDF]  

Expression of an Estramustine-binding Associated Protein in Human Lung Cancer Cell Lines

Jonas Bergh, Per Björk, Jan-Erik Westlin, and Sten Nilsson
Cancer Res 1988 48: 4615-4619. [Abstract] [PDF]  

Characterization of Normal Human Exocervical Epithelial Cells Immortalized in Vitro by Papillomavirus Types 16 and 18 DNA

C. D. Woodworth, P. E. Bowden, J. Doniger, L. Pirisi, W. Barnes, W. D. Lancaster, and J. A. DiPaolo
Cancer Res 1988 48: 4620-4628. [Abstract] [PDF]  

Variation in Tumor Yield in the Prostate and Other Target Organs of the Rat in Response to Varied Dosage and Duration of Administration of 3,2'-Dimethyl-4-aminobiphenyl

Nobuyuki Ito, Tomoyuki Shirai, Yoshiaki Tagawa, Atsushi Nakamura, and Shoji Fukushima
Cancer Res 1988 48: 4629-4632. [Abstract] [PDF]  

Protein-Tyrosine Kinase Activity and pp60^v-src Expression in Whole Cells Measured by Flow Cytometry

Peter N. Preis, Frederic M. Waldman, A. Raymond Frackelton, Jr., Hideyuki Saya, and Victor A. Levin
Cancer Res 1988 48: 4633-4638. [Abstract] [PDF]  

Three Novel Mouse Monoclonal Antibodies, OM-A, OM-B, and OM-C, Reactive with Mucinous Type Ovarian Tumors

Katsumi Sakakibara, Ryuzo Ueda, Masahiro Ohta, Nobuo Nakashima, Yutaka Tomoda, and Toshitada Takahashi
Cancer Res 1988 48: 4639-4645. [Abstract] [PDF]  

Contrasting Actions of Staurosporine, a Protein Kinase C Inhibitor, on Human Neutrophils and Primary Mouse Epidermal Cells

Takashi Sako, Alfred I. Tauber, Arco Y. Jeng, Stuart H. Yuspa, and Peter M. Blumberg
Cancer Res 1988 48: 4646-4650. [Abstract] [PDF]  

Partial Inhibition of the Growth of Transplanted Dunning Rat Prostate Tumors with the Long-Acting Somatostatin Analogue Sandostatin (SMS 201–995)

R. A. Siegel, L. Tolcsvai, and M. Rudin
Cancer Res 1988 48: 4651-4655. [Abstract] [PDF]  

Cadmium Carcinogenesis in Male Wistar [Crl:(WI)BR] Rats: Dose-Response Analysis of Tumor Induction in the Prostate and Testes and at the Injection Site

Michael P. Waalkes, Sabine Rehm, Charles W. Riggs, Robert M. Bare, Deborah E. Devor, Lionel A. Poirier, Martin L. Wenk, John R. Henneman, and Michael S. Balaschak
Cancer Res 1988 48: 4656-4663. [Abstract] [PDF]  

Experimental Therapy of Human Breast Tumors with ¹³¹I-labeled Monoclonal Antibodies Prepared against the Human Milk Fat Globule

Roberto L. Ceriani and Edward W. Blank
Cancer Res 1988 48: 4664-4672. [Abstract] [PDF]  

Efficient Transplantation of Human Non-T-Leukemia Cells into Nude Mice and Induction of Complete Regression of the Transplanted Distinct Tumors by Ricin A-Chain Conjugates of Monoclonal Antibodies SN5 and SN6

Hideki Hara, Yi Luo, Yuro Haruta, and Ben K. Seon
Cancer Res 1988 48: 4673-4680. [Abstract] [PDF]  

Isolation and Characterization of Cytotoxic Granules from Human Lymphokine (Interleukin 2) Activated Killer Cells

David M. Lowrey, Arif Hameed, Mathias Lichtenheld, and Eckhard R. Podack
Cancer Res 1988 48: 4681-4688. [Abstract] [PDF]  

Transformation of Human Mammary Epithelial Cells by Oncogenic Retroviruses

Robin Clark, Martha R. Stampfer, Robert Milley, Edward O'Rourke, Kirsten H. Walen, Michael Kriegler, Joanne Kopplin, and Frank McCormick
Cancer Res 1988 48: 4689-4694. [Abstract] [PDF]  

Clinical and Epidemiological Investigations:

Long-Lasting Effects of Tobacco Smoking on Pulmonary Drug-metabolizing Enzymes: A Case-Control Study on Lung Cancer Patients

Stefano Petruzzelli, Anne-Marie Camus, Laura Carrozzi, Letizia Ghelarducci, Maurizio Rindi, Gianfranco Menconi, Carlo A. Angeletti, Markku Ahotupa, Eino Hietanen, Antero Aitio, Rodolfo Saracci, Helmut Bartsch, and Carlo Giuntini
Cancer Res 1988 48: 4695-4700. [Abstract] [PDF]  

A Randomized Trial of Vitamins C and E in the Prevention of Recurrence of Colorectal Polyps

Gail McKeown-Eyssen, Catherine Holloway, Vartouhi Jazmaji, Elizabeth Bright-See, Peter Dion, and W. Robert Bruce
Cancer Res 1988 48: 4701-4705. [Abstract] [PDF]  

Phase I and Clinical Pharmacology Trial of Crisnatol (BWA770U Mesylate) Using a Monthly Single-Dose Schedule

Glenn S. Harman, John B. Craig, John G. Kuhn, J. Scott Luther, Judy N. Turner, Geoffrey R. Weiss, Dennis A. Tweedy, Jim Koeller, Richard L. Tuttle, V. Sol Lucas, William Wargin, John K. Whisnant, and Daniel D. Von Hoff
Cancer Res 1988 48: 4706-4710. [Abstract] [PDF]  

Meeting Report:

Ninth International Meeting on N-Nitroso Compounds: Exposures, Mechanisms, and Relevance to Human Cancer

Helmut Bartsch and Ian K. O'Neill
Cancer Res 1988 48: 4711-4714. [PDF]  

Articles:

Announcements

Cancer Res 1988 48: 4715 [PDF]  

Erratum:

The Contribution of Medicine to the Primary Treatment of Breast Cancer

Cancer Res 1988 48: 4716 [PDF]  

Resistance of Human Leukemic and Normal Lymphocytes to Drug-induced DNA Cleavage and Low Levels of DNA Topoisomerase II

Cancer Res 1988 48: 4716 [PDF]  

Evaluation of Ricin A Chaincontaining Immunotoxins Directed against CD19 and CD22 Antigens on Normal and Malignant Human B-Cells as Potential Reagents for in Vivo Therapy

Cancer Res 1988 48: 4716 [PDF]  

Radioimmunotherapy of Human Colonic Cancer Xenografts with ⁹⁰Y-labeled Monoclonal Antibodies to Carcinoembryonic Antigen

Cancer Res 1988 48: 4716 [PDF]  

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