Perspectives in Cancer Research:

Cancer as a Disease of DNA Organization and Dynamic Cell Structure

Kenneth J. Pienta, Alan W. Partin, and Donald S. Coffey
Cancer Res 1989 49: 2525-2532. [PDF]  

REVIEWS:

Growth Factors in the Regulation of Pericellular Proteolysis: A Review

Marikki Laiho and Jorma Keski-Oja
Cancer Res 1989 49: 2533-2553. [PDF]  

Basic Sciences:

Persistence of the Hypertriglyceridemic Effect of Tumor Necrosis Factor Despite Development of Tachyphylaxis to Its Anorectic/Cachectic Effects in Rats

Carl Grunfeld, Helga Wilking, Richard Neese, Larry A. Gavin, Arthur H. Moser, Rocco Gulli, M. Kerala Serio, and Kenneth R. Feingold
Cancer Res 1989 49: 2554-2560. [Abstract] [PDF]  

Most Effective Route of Administration and Utilization of High-Dose Chemotherapy with Bone Marrow Transplantation in Rats

Yutaka Mizushima, Toshihiko Morikage, Kouitsu Sasaki, and Saburo Yano
Cancer Res 1989 49: 2561-2566. [Abstract] [PDF]  

Effects of Pyrimidine Nucleoside Phosphorylase Inhibitors on Hepatic Fluoropyrimidine Elimination in the Rat

Frank P. LaCreta, Barbour S. Warren, and Walter M. Williams
Cancer Res 1989 49: 2567-2573. [Abstract] [PDF]  

Myeloprotective Effect of Diethyldithiocarbamate Treatment following 1,3-Bis(2-chloroethyl)-1-nitrosourea, Adriamycin, or Mitomycin C in Mice

Therese K. Schmalbaçh and Richard F. Borch
Cancer Res 1989 49: 2574-2577. [Abstract] [PDF]  

In Vitro and Intracellular Inhibition of Topoisomerase II by the Antitumor Agent Merbarone

Fred H. Drake, Glenn A. Hofmann, Shau-Ming Mong, Joan O'Leary Bartu, Robert P. Hertzberg, Randall K. Johnson, Michael R. Mattern, and Christopher K. Mirabelli
Cancer Res 1989 49: 2578-2583. [Abstract] [PDF]  

Inhibition of Carcinogen-inducible DNA Amplification in a Simian Virus 40-transformed Hamster Cell Line by Ethacridine or Ethanol

Alexander Bürkle
Cancer Res 1989 49: 2584-2587. [Abstract] [PDF]  

Intratumoral Aromatase as a Prognostic Factor in Human Breast Carcinoma

Marigilka C. Silva, Martin G. Rowlands, Mitch Dowsett, Barry Gusterson, J. Alan McKinna, Ian Fryatt, and R. Charles Coombes
Cancer Res 1989 49: 2588-2591. [Abstract] [PDF]  

Selective Expansion of 5,10-Methylenetetrahydrofolate Pools and Modulation of 5-Fluorouracil Antitumor Activity by Leucovorin in Vivo

Joel E. Wright, Arnon Dreyfuss, Ibrahim El-Magharbel, Dorothy Trites, Steven M. Jones, Sylvia A. Holden, Andre Rosowsky, and Emil Frei, III
Cancer Res 1989 49: 2592-2596. [Abstract] [PDF]  

Possible Involvement of Ca²⁺ Mobilization and Protein Kinase C Activation in the Induction of Spontaneous Metastasis by Mouse Mammary Adenocarcinoma Cells

Bozena Korczak, Capucine Whale, and R. S. Kerbel
Cancer Res 1989 49: 2597-2602. [Abstract] [PDF]  

Formation of 8-Hydroxydeoxyguanosine in Liver DNA of Rats following Long-Term Exposure to a Peroxisome Proliferator

H. Kasai, Y. Okada, S. Nishimura, M. S. Rao, and J. K. Reddy
Cancer Res 1989 49: 2603-2605. [Abstract] [PDF]  

Role of Tumor Necrosis Factor and Interleukin 1 in -Interferon-promoted Activation of Mouse Tumoricidal Macrophages

Kazuyoshi Hori, Enrico Mihich, and M. Jane Ehrke
Cancer Res 1989 49: 2606-2614. [Abstract] [PDF]  

Ligand-induced Phosphorylation of a Murine Tumor Surface Protein (TSP-180) Associated with Metastatic Phenotype

A. Sacchi, R. Falcioni, G. Piaggio, M. A. Gianfelice, N. Perrotti, and S. J. Kennel
Cancer Res 1989 49: 2615-2620. [Abstract] [PDF]  

Denitrosation of 1,3-Bis(2-chloroethyl)-1-nitrosourea by Class Mu Glutathione Transferases and Its Role in Cellular Resistance in Rat Brain Tumor Cells

Martyn T. Smith, Celia G. Evans, Penelope Doane-Setzer, Victor M. Castro, M. Kalim Tahir, and Bengt Mannervik
Cancer Res 1989 49: 2621-2625. [Abstract] [PDF]  

Early Expression of Glycophorin C during Normal and Leukemic Human Erythroid Differentiation

Jean-Luc Villeval, Caroline Le Van Kim, Ali Bettaieb, Najet Debili, Yves Colin, Bouchra El Maliki, Dominique Blanchard, William Vainchenker, and Jean-Pierre Cartron
Cancer Res 1989 49: 2626-2632. [Abstract] [PDF]  

Effects of Route of Administration on Tissue Distribution of DNA Adducts in Mice: Comparison of 7H-Dibenzo(c,g)carbazole, Benzo(a)pyrene, and 2-Acetylaminofluorene

Mark E. Schurdak and Kurt Randerath
Cancer Res 1989 49: 2633-2638. [Abstract] [PDF]  

Nature of the Bifunctional Chelating Agent Used for Radioimmunotherapy with Yttrium-90 Monoclonal Antibodies: Critical Factors in Determining in Vivo Survival and Organ Toxicity

Robert W. Kozak, Andrew Raubitschek, Saed Mirzadeh, Martin W. Brechbiel, Richard Junghaus, Otto A. Gansow, and Thomas A. Waldmann
Cancer Res 1989 49: 2639-2644. [Abstract] [PDF]  

Dual Effects of Pyrazofurin and 3-Deazauridine upon Pyrimidine and Purine Biosynthesis in Mouse L1210 Leukemia

Melissa E. Sant, Stephen D. Lyons, Anthony J. Kemp, Linda K. McClure, Eve Szabados, and Richard I. Christopherson
Cancer Res 1989 49: 2645-2650. [Abstract] [PDF]  

Modulation of Carcinoembryonic Antigen Messenger RNA Levels in Human Colon Carcinoma Cells by Recombinant Human -Interferon

Judy Kantor, Rosette Tran, John Greiner, Sidney Pestka, Paul B. Fisher, John E. Shively, and Jeffrey Schlom
Cancer Res 1989 49: 2651-2655. [Abstract] [PDF]  

Augmentation of 1-ß-D-Arabinofuranosylcytosine Cytotoxicity in Human Tumor Cells by Inhibiting Drug Efflux

Thomas C. K. Chan
Cancer Res 1989 49: 2656-2660. [Abstract] [PDF]  

Modulation of Doxorubicin Resistance by Valinomycin (NSC 122023) and Liposomal Valinomycin in Chinese Hamster Ovary Cells

Sayed S. Daoud and R. L. Juliano
Cancer Res 1989 49: 2661-2667. [Abstract] [PDF]  

Alteration of the c-mos Locus in "Normal" Tissues from Humans Exposed to Radium

J. P. Hardwick, R. A. Schlenker, and E. Huberman
Cancer Res 1989 49: 2668-2673. [Abstract] [PDF]  

Characterization of a Cisplatin-resistant Subline of Murine RIF-1 Cells and Reversal of Drug Resistance by Hyperthermia

Ali Mansouri, Kurt J. Henle, Ann M. Benson, Alfred J. Moss, and William A. Nagle
Cancer Res 1989 49: 2674-2678. [Abstract] [PDF]  

Stimulation of Growth in Human and Murine Cells by Adriamycin

Paul Vichi and Thomas R. Tritton
Cancer Res 1989 49: 2679-2682. [Abstract] [PDF]  

Expression and Amplification of myc Gene Family in Small Cell Lung Cancer and Its Relation to Biological Characteristics

Takashi Takahashi, Yuichi Obata, Yoshitaka Sekido, Toyoaki Hida, Ryuzo Ueda, Hiroyoshi Watanabe, Yutaka Ariyoshi, Takahito Sugiura, and Toshitada Takahashi
Cancer Res 1989 49: 2683-2688. [Abstract] [PDF]  

Inhibition of N-Nitrosodiethylamine Carcinogenesis in Mice by Naturally Occurring Organosulfur Compounds and Monoterpenes

Lee W. Wattenberg, Velta L. Sparnins, and George Barany
Cancer Res 1989 49: 2689-2692. [Abstract] [PDF]  

Optimization of Perfluorochemical Levels with Radiation Therapy in Mice

Beverly A. Teicher, Terence S. Herman, and Steven M. Jones
Cancer Res 1989 49: 2693-2697. [Abstract] [PDF]  

Effects of Type I and II Interferons on Cultured Human Breast Cells: Interaction with Estrogen Receptors and with Tamoxifen

D. Goldstein, S. M. Bushmeyer, P. L. Witt, V. C. Jordan, and E. C. Borden
Cancer Res 1989 49: 2698-2702. [Abstract] [PDF]  

2,3,7,8-Tetrachlorodibenzo-p-dioxin Enhancement of N-Methyl-N'-nitro-N-nitrosoguanidine-induced Transformation of Rat Tracheal Epithelial Cells in Culture

Noriho Tanaka, Paul Nettesheim, Thomas Gray, Karen Nelson, and J. Carl Barrett
Cancer Res 1989 49: 2703-2708. [Abstract] [PDF]  

Correlation of Natural Killer Activity with Tumorigenesis of a Preneoplastic Mouse Mammary Lesion

Wei-Zen Wei, Amy Fulton, Jeff Winkelhake, and Gloria Heppner
Cancer Res 1989 49: 2709-2715. [Abstract] [PDF]  

Loss of the Same Alleles of HRAS1 and D11S151 in Two Independent Pancreatic Cancers from a Patient with Multiple Endocrine Neoplasia Type 1

Katsuhiko Yoshimoto, Masayoshi Iizuka, Hiroyuki Iwahana, Ryuichi Yamasaki, Haruhiko Saito, Shiro Saito, and Takao Sekiya
Cancer Res 1989 49: 2716-2721. [Abstract] [PDF]  

Association of Lysosomal Activity with Sensitivity and Resistance to Tumor Necrosis Factor in Murine L929 Cells

James D. Liddil, Robert T. Dorr, and Philip Scuderi
Cancer Res 1989 49: 2722-2728. [Abstract] [PDF]  

Characterization of the Multidrug Resistance Protein Expressed in Cell Clones Stably Transfected with the Mouse mdr1 cDNA

Erwin Schurr, Martine Raymond, John C. Bell, and Philippe Gros
Cancer Res 1989 49: 2729-2734. [Abstract] [PDF]  

Correlation between the Induction of Heat Shock Protein 70 and Enhanced Viral Reactivation in Mammalian Cells Treated with Ultraviolet Light and Heat Shock

Kandace J. Williams, Bryan E. Landgraf, Narda L. Whiting, and Joanne Zurlo
Cancer Res 1989 49: 2735-2742. [Abstract] [PDF]  

Sensitivity of Hamster Tracheal Epithelial Cells to Asbestiform Minerals Modulated by Serum and by Transforming Growth Factor ß

Ann Marie Sesko and Brooke T. Mossman
Cancer Res 1989 49: 2743-2749. [Abstract] [PDF]  

Mesenchymal-Epithelial Interactions between Normal and Transformed Human Bladder Cells

T. Rand Pritchett, Julia K. M. Wang, and Peter A. Jones
Cancer Res 1989 49: 2750-2754. [Abstract] [PDF]  

Corticotropin-releasing Factor and Vasopressin Production in the Rat Pituitary Tumor 7315a: Biochemical and Immunohistochemical Studies

María Inés Morano and Fernando E. Estivariz
Cancer Res 1989 49: 2755-2760. [Abstract] [PDF]  

Aberrant Postendocytotic Fate of a 34-kDa Molecular Mass Growth Factor from Human Trophoblasts

Manjusri Das, Shyam S. Chauhan, Vishnu S. Mishra, Jean M. Sanger, Joseph W. Sanger, and Susanta Roy-Choudhury
Cancer Res 1989 49: 2761-2765. [Abstract] [PDF]  

Murine Monoclonal IgG3 Antibodies to Human Colorectal Tumor-associated Antigens: Production and Characterization of Antibodies Active in Both Antibody-dependent Cellular Cytotoxicity and Complement-mediated Cytolysis

Clive S. Woodhouse and Alton C. Morgan, Jr.
Cancer Res 1989 49: 2766-2772. [Abstract] [PDF]  

Murine Monoclonal IgG3 to Human Colorectal Tumor-associated Antigens: Enhancement of Antibody-dependent Cell-mediated Cytotoxicity by Interleukin 2

Alton C. Morgan, Jr., Wendy Sullivan, Scott Graves, and Clive S. Woodhouse
Cancer Res 1989 49: 2773-2776. [Abstract] [PDF]  

Hyperthermia, Tissue Microcirculation, and Temporarily Increased Thermosensitivity in VX2 Carcinoma in Rabbit Liver

Hiroyuki Matsuda, Keizo Sugimachi, Hiroyuki Kuwano, and Masaki Mori
Cancer Res 1989 49: 2777-2782. [Abstract] [PDF]  

Local Distribution and Concentration of Intravenously Injected ¹³¹I-9.2.27 Monoclonal Antibody in Human Malignant Melanoma

Silvana Del Vecchio, James C. Reynolds, Jorge A. Carrasquillo, Ronald G. Blasberg, Ronald D. Neumann, Michael T. Lotze, Gail J. Bryant, Raymond J. Farkas, and Steven M. Larson
Cancer Res 1989 49: 2783-2789. [Abstract] [PDF]  

P-Glycoprotein Expression in Multidrug-resistant Human Ovarian Carcinoma Cell Lines

Grace Bradley, Michael Naik, and Victor Ling
Cancer Res 1989 49: 2790-2796. [Abstract] [PDF]  

Phenotypic Heterogeneity Studied by Immunohistochemistry and Aneuploidy in Non-Small Cell Lung Cancers

Jean-Louis Pujol, Joëlle Simony, Jean-Claude Laurent, Gilbert Richer, Henri Mary, Jean Bousquet, Philippe Godard, and François-Bernard Michel
Cancer Res 1989 49: 2797-2802. [Abstract] [PDF]  

Clinical and Epidemiological Investigations:

Risk Factors for Oral Cancer in Women

Geoffrey C. Kabat, James R. Hebert, and Ernst L. Wynder
Cancer Res 1989 49: 2803-2806. [Abstract] [PDF]  

Pharmacokinetics and Tumor Localization of ¹³¹I-Labeled Anti-Tenascin Monoclonal Antibody 81C6 in Patients with Gliomas and Other Intracranial Malignancies

Michael R. Zalutsky, Robin P. Moseley, Hugh B. Coakham, R. Edward Coleman, and Darell D. Bigner
Cancer Res 1989 49: 2807-2813. [Abstract] [PDF]  

Meeting Report:

Second Heidelberger Conference on Transformation and Differentiation in Vitro

Cancer Res 1989 49: 2814-2817. [PDF]  

Articles:

Announcements

Cancer Res 1989 49: 2818-2820. [PDF]  

Recent Death

Cancer Res 1989 49: 2820 [PDF]  

Calendar of Events

Cancer Res 1989 49: 2820 [PDF]  

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