Perspectives in Cancer Research:

Reducing Avoidable Cancer Mortality through Prevention and Early Detection Regimens

Caryn Lerman, Barbara Rimer, and Paul F. Engstrom
Cancer Res 1989 49: 4955-4962. [PDF]  

Basic Sciences:

Inhibitory Effect of Antibody against Basic Fibroblast Growth Factor on Androgen- or Glucocorticoid-induced Growth of Shionogi Carcinoma 115 Cells in Serum-free Culture

Jian Lu, Yasuko Nishizawa, Akira Tanaka, Norio Nonomura, Hiroshi Yamanishi, Naomi Uchida, Bunzo Sato, and Keishi Matsumoto
Cancer Res 1989 49: 4963-4967. [Abstract] [PDF]  

Differential Expression of the c-erbB-2 Gene in Human Small Cell and Non-Small Cell Lung Cancer

Paul M. Schneider, Mien-Chie Hung, Susanna M. Chiocca, John Manning, Xiaoyan Zhao, Kang Fang, and Jack A. Roth
Cancer Res 1989 49: 4968-4971. [Abstract] [PDF]  

Biochemical Pharmacology of 2-Chlorodeoxyadenosine in Malignant Human Hematopoietic Cell Lines and Therapeutic Effects of 2-Bromodeoxyadenosine in Drug Combinations in Mice

Thomas L. Avery, Jerold E. Rehg, Wendy C. Lumm, Franklin C. Harwood, Victor M. Santana, and Raymond L. Blakley
Cancer Res 1989 49: 4972-4978. [Abstract] [PDF]  

Adoptive Immunotherapy as an Adjunctive Treatment to Thoracic Irradiation for Pulmonary Tumor Deposits in Mice

Luka Milas, Gregor Sersa, Veronica Willingham, Nancy Hunter, and Shiao Woo
Cancer Res 1989 49: 4979-4982. [Abstract] [PDF]  

Mechanism of Adenosine Triphosphate Catabolism Induced by Deoxyadenosine and by Nucleoside Analogues in Adenosine Deaminase-inhibited Human Erythrocytes

Françoise Bontemps and Georges Van den Berghe
Cancer Res 1989 49: 4983-4989. [Abstract] [PDF]  

Enhanced Therapeutic Efficacy of an Immunotoxin in Combination with Chemotherapy against an Intraperitoneal Human Tumor Xenograft in Athymic Mice

John W. Pearson, Gowsala Sivam, Ron Manger, Robert H. Wiltrout, A. C. Morgan, Jr., and Dan L. Longo
Cancer Res 1989 49: 4990-4995. [Abstract] [PDF]  

Evidence for Enzymatic Activation and Oxygen Involvement in Cytotoxicity and Antitumor Activity of N,N',N''-Triethylenethiophosphoramide

Beverly A. Teicher, David J. Waxman, Sylvia A. Holden, Yenyun Wang, Lynn Clarke, Enrique Alvarez Sotomayor, Steven M. Jones, and Emil Frei, III
Cancer Res 1989 49: 4996-5001. [Abstract] [PDF]  

Reversal Mechanism of Multidrug Resistance by Verapamil: Direct Binding of Verapamil to P-Glycoprotein on Specific Sites and Transport of Verapamil Outward across the Plasma Membrane of K562/ADM Cells

Keisuke Yusa and Takashi Tsuruo
Cancer Res 1989 49: 5002-5006. [Abstract] [PDF]  

Lysis of Antigenically Unrelated Tumor Cells Mediated by Lyt 2⁺ Splenic T-Cells from Melphalan-cured MOPC-315 Tumor Bearers

Edward Barker, James A. Wise, Sheldon Dray, and Margalit B. Mokyr
Cancer Res 1989 49: 5007-5015. [Abstract] [PDF]  

Protein-linked DNA Strand Breaks Induced in Mammalian Cells by Camptothecin, an Inhibitor of Topoisomerase I

Joseph M. Covey, Christine Jaxel, Kurt W. Kohn, and Yves Pommier
Cancer Res 1989 49: 5016-5022. [Abstract] [PDF]  

Metabolism and Murine Pharmacokinetics of the 8-(N,N-Dimethylcarboxamide) Analogue of the Experimental Antitumor Drug Mitozolomide (NSC353451)

Keith R. Horspool, Charmaine P. Quarterman, John A. Slack, Andreas Gescher, Malcolm F. G. Stevens, and Edward Lunt
Cancer Res 1989 49: 5023-5026. [Abstract] [PDF]  

Influence of Cellular, Microenvironmental, and Growth Parameters on Thermotolerance Kinetics in Vivo in Human Melanoma Xenografts

Einar K. Rofstad
Cancer Res 1989 49: 5027-5032. [Abstract] [PDF]  

Expression of Messenger RNA Species Coding for a M_r 43,000 Peptide Associated with Ferritin in Human Leukemia-K562 Cells and Its Down Regulation during Differentiation

Nava Shterman, Batia Kupfer, and Chaya Moroz
Cancer Res 1989 49: 5033-5036. [Abstract] [PDF]  

Induction of Human Monocyte Susceptibility to Lymphokine-activated Killer Cell Lysis by Granulocyte-Macrophage Colony-stimulating Factor

D. Kay Blanchard, Debbie Serbousek, and Julie Y. Djeu
Cancer Res 1989 49: 5037-5043. [Abstract] [PDF]  

Genetic Variation in Liver Tumor Susceptibility, Plasma Testosterone Levels, and Androgen Receptor Binding in Six Inbred Strains of Mice

Christopher J. Kemp and Norman R. Drinkwater
Cancer Res 1989 49: 5044-5047. [Abstract] [PDF]  

Mechanism of Transport and Intracellular Binding of Porfiromycin in HCT 116 Human Colon Carcinoma Cells

Su-shu Pan, Robin Johnson, Hector Gonzalez, and Vinay Thohan
Cancer Res 1989 49: 5048-5053. [Abstract] [PDF]  

Association among DNA/Chromosome Break Rejoining Rates, Chromatin Structure Alterations, and Radiation Sensitivity in Human Cell Lines

Jeffrey L. Schwartz and Andrew T. M. Vaughan
Cancer Res 1989 49: 5054-5057. [Abstract] [PDF]  

Immunological and Pharmacological Removal of Small Cell Lung Cancer Cells from Bone Marrow Autografts

Y. Humblet, A-M. Feyens, M. Sekhavat, D. Agaliotis, J-L. Canon, and M. L. Symann
Cancer Res 1989 49: 5058-5061. [Abstract] [PDF]  

Expression of a Human Multidrug Resistance Gene in Ovarian Carcinomas

Jean Bourhis, Lori J. Goldstein, Guy Riou, Ira Pastan, Michael M. Gottesman, and Jean Bénard
Cancer Res 1989 49: 5062-5065. [Abstract] [PDF]  

Effects of Irradiation on the Release of Growth Factors from Cultured Bovine, Porcine, and Human Endothelial Cells

Larry Witte, Zvi Fuks, Adriana Haimovitz-Friedman, Israel Vlodavsky, DeWitt S. Goodman, and Amiram Eldor
Cancer Res 1989 49: 5066-5072. [Abstract] [PDF]  

Role of Ornithine Decarboxylase in Diallyl Sulfide Inhibition of Colonic Radiation Injury in the Mouse

Allan R. Baer and Michael J. Wargovich
Cancer Res 1989 49: 5073-5076. [Abstract] [PDF]  

Arrest of Replication Forks by Drug-stabilized Topoisomerase I-DNA Cleavable Complexes as a Mechanism of Cell Killing by Camptothecin

Yaw-Huei Hsiang, Michelle G. Lihou, and Leroy F. Liu
Cancer Res 1989 49: 5077-5082. [Abstract] [PDF]  

The Effect of Vitamin D₃ on the Production of Cytotoxic Factors by Human Peripheral Blood Mononuclear Cells

Shookooh Yousefi, Dinh Vu, Gloria Carandang, Robert Yamamoto, Gale Granger, N. Vaziri, J. Ocariz, and Thomas Cesario
Cancer Res 1989 49: 5083-5086. [Abstract] [PDF]  

Regional Loss of Chromosome 6 in Two Urological Malignancies

Daniel B. Rukstalis, Glenn J. Bubley, John P. Donahue, Jerome P. Richie, J. G. Seidman, and William C. DeWolf
Cancer Res 1989 49: 5087-5090. [Abstract] [PDF]  

Antigenic Profile of Tumor Progression Stages in Human Melanocytic Nevi and Melanomas

David E. Elder, Ulrich Rodeck, Jan Thurin, Francis Cardillo, Wallace H. Clark, Rosemary Stewart, and Meenhard Herlyn
Cancer Res 1989 49: 5091-5096. [Abstract] [PDF]  

Therapy of Central Nervous System Leukemia in Mice by Liposome-entrapped 1-ß-D-Arabinofuranosylcytosine

Feng Hong and Eric Mayhew
Cancer Res 1989 49: 5097-5102. [Abstract] [PDF]  

Controlled Delivery of 1,3-Bis(2-chloroethyl)-1-nitrosourea from Ethylene-Vinyl Acetate Copolymer

Michael B. Yang, Rafael J. Tamargo, and Henry Brem
Cancer Res 1989 49: 5103-5107. [Abstract] [PDF]  

Comparison of the Mechanism of Action of Busulfan with Hepsulfam, a New Antileukemic Agent, in the L1210 Cell Line

Diane Y. Pacheco, Nancy K. Stratton, and Neil W. Gibson
Cancer Res 1989 49: 5108-5110. [Abstract] [PDF]  

Inhibitory Effects of the Tyrosine Kinase Inhibitor Genistein on Mammalian DNA Topoisomerase II

Judith Markovits, Claude Linassier, Philippe Fossé, Jeanine Couprie, Josiane Pierre, Alain Jacquemin-Sablon, Jean-Marie Saucier, Jean-Bernard Le Pecq, and Annette K. Larsen
Cancer Res 1989 49: 5111-5117. [Abstract] [PDF]  

Lung Cancer-associated Monoclonal Antibody 15 That Recognizes Cell Growth-related Membrane Antigens gp85/45 and Its Growth-inhibitory Effect on Human Lung Cancer Cells in Vitro

Hiroshi Kamma, Katsuyuki Endo, Hisashi Horiguchi, Tatsuo Iijima, and Takesaburo Ogata
Cancer Res 1989 49: 5118-5122. [Abstract] [PDF]  

Effect of Doxorubicin on Mouse Hybridoma B Cells: Stimulation of Immunoglobulin Synthesis and Secretion

Jean-Luc Teillaud, Alain Fourcade, Joseph Huppert, Wolf H. Fridman, and Haim Tapiero
Cancer Res 1989 49: 5123-5129. [Abstract] [PDF]  

Concordant Deletions of Chromosome 3p and Loss of Heterozygosity for Chromosomes 13 and 17 in Small Cell Lung Carcinoma

Naoki Mori, Jun Yokota, Mitsuo Oshimura, Webster K. Cavenee, Hideaki Mizoguchi, Masayuki Noguchi, Yukio Shimosato, Takashi Sugimura, and Masaaki Terada
Cancer Res 1989 49: 5130-5135. [Abstract] [PDF]  

Autocrine Growth Factor in Defined Serum-free Medium of Human Salivary Gland Adenocarcinoma Cell Line HSG

Riki Kurokawa, Seiko Kyakumoto, and Minoru Ota
Cancer Res 1989 49: 5136-5142. [Abstract] [PDF]  

Promotion by Dihydroxybenzene Derivatives of N-Methyl-N'-nitro-N-nitrosoguanidine-induced F344 Rat Forestomach and Glandular Stomach Carcinogenesis

Masao Hirose, Shuji Yamaguchi, Shoji Fukushima, Ryohei Hasegawa, Satoshi Takahashi, and Nobuyuki Ito
Cancer Res 1989 49: 5143-5147. [Abstract] [PDF]  

A Human Tumor Lung Metastasis Model in Athymic Nude Rats

Inge Kjønniksen, Ritsa Storeng, Alexander Pihl, Theodore L. McLemore, and Øystein Fodstad
Cancer Res 1989 49: 5148-5152. [Abstract] [PDF]  

Establishment and Characterization of a Human Ovarian Neoplastic Cell Line, DO-s

Tony W. Briers, Patricia Stroobants, Tanja M. Vandeputte, Etienne J. Nouwen, M. Viviane Conraads, Gerard Eestermans, D. Van Bockstaele, and Marc. E. De Broe
Cancer Res 1989 49: 5153-5161. [Abstract] [PDF]  

Detection of an Intrinsic Marker in Hypoxic Cells

Lynn Hlatky, Christine S. Ring, and Rainer K. Sachs
Cancer Res 1989 49: 5162-5166. [Abstract] [PDF]  

Biology, Cytogenetics, and Sensitivity to Immunological Effector Cells of New Head and Neck Squamous Cell Carcinoma Lines

D. S. Heo, C. Snyderman, S. M. Gollin, S. Pan, E. Walker, R. Deka, E. L. Barnes, J. T. Johnson, R. B. Herberman, and T. L. Whiteside
Cancer Res 1989 49: 5167-5175. [Abstract] [PDF]  

Comparison of an Immunocytochemical Assay for Progesterone Receptor with a Biochemical Method of Measurement and Immunocytochemical Examination of the Relationship between Progesterone and Estrogen Receptors

Uta Berger, Pat Wilson, Suki Thethi, Richard A. McClelland, Geoffrey L. Greene, and R. Charles Coombes
Cancer Res 1989 49: 5176-5179. [Abstract] [PDF]  

Role of 2'-5'-Oligoadenylate Synthetase in -Interferon-mediated Growth Inhibition of A431 Cells

Rakesh Kumar and John Mendelsohn
Cancer Res 1989 49: 5180-5184. [Abstract] [PDF]  

Association of Low nm23 RNA Levels in Human Primary Infiltrating Ductal Breast Carcinomas with Lymph Node Involvement and Other Histopathological Indicators of High Metastatic Potential

Generoso Bevilacqua, Mark E. Sobel, Lance A. Liotta, and Patricia S. Steeg
Cancer Res 1989 49: 5185-5190. [Abstract] [PDF]  

Altered Function of Protein Kinase C and Cyclic Adenosine Monophosphate-dependent Protein Kinase in a Cell Line Derived from a Mouse Lung Papillary Tumor

Kendal M. Nicks, Kurt A. Droms, Tellef Fossli, Garry J. Smith, and Alvin M. Malkinson
Cancer Res 1989 49: 5191-5198. [Abstract] [PDF]  

Loss of Calcitonin Receptors: A Genetically Transmitted Defect in Rats with High Incidence of C-Cell Tumors

Z. Bouizar, S. Minvielle, F. Treilhou-Lahille, W. H. Rostene, E. Pidoux, N. Feingold, G. Milhaud, and M. S. Moukhtar
Cancer Res 1989 49: 5199-5202. [Abstract] [PDF]  

Clinical and Epidemiological Investigations:

Breast Cancer and Alcohol Consumption: A Case-Control Study in Northern Italy

Paolo Toniolo, Elio Riboli, Fulvia Protta, Martine Charrel, and Alberto P. M. Cappa
Cancer Res 1989 49: 5203-5206. [Abstract] [PDF]  

Biological Amplification Factor for Sunlight-induced Nonmelanoma Skin Cancer at High Latitudes

Johan Moan, Arne Dahlback, Thormod Henriksen, and Knut Magnus
Cancer Res 1989 49: 5207-5212. [Abstract] [PDF]  

Phase I Trial and Pharmacokinetic Evaluation of Fazarabine in Children

Richard L. Heideman, Andrea Gillespie, Harry Ford, Gregory H. Reaman, Frank M. Balis, Charlotte Tan, Judy Sato, Lawrence J. Ettinger, Roger J. Packer, and David G. Poplack
Cancer Res 1989 49: 5213-5216. [Abstract] [PDF]  

Phase I Clinical Study of N-[(4-Chlorophenyl)amino]carbonyl-2,3-dihydro-1H-indene-5-sulfonamide (LY186641)

John D. Hainsworth, Kenneth R. Hande, Winston G. Satterlee, John Kuttesch, David H. Johnson, Gerald Grindey, Linda E. Jackson, and F. Anthony Greco
Cancer Res 1989 49: 5217-5220. [Abstract] [PDF]  

Dose Escalation Study of Recombinant Human Granulocyte-Colony-stimulating Factor (KRN8601) in Patients with Advanced Malignancy

Kenji Eguchi, Satoru Sasaki, Tomohide Tamura, Yasutsuna Sasaki, Tetsu Shinkai, Kouzou Yamada, Yoshifumi Soejima, Masaaki Fukuda, Yasuhiro Fujihara, Hideo Kunitou, Kensei Tobinai, Tomoko Ohtsu, Keiichi Suemasu, Fumimaro Takaku, and Nagahiro Saijo
Cancer Res 1989 49: 5221-5224. [Abstract] [PDF]  

Elevation of the Placental Glutathione S-Transferase Form (GST-) in Tumor Tissues and the Levels in Sera of Patients with Cancer

Shigeki Tsuchida, Yoshihito Sekine, Ryuzaburo Shineha, Tetsuro Nishihira, and Kiyomi Sato
Cancer Res 1989 49: 5225-5229. [Abstract] [PDF]  

Differences between in Vivo and in Vitro Activation of Cancer Patient Lymphocytes by Recombinant Interleukin 2: Possible Role for Lymphokine-activated Killer Cell Infusion in the in Vivo-induced Activation

Carlo Gambacorti-Passerini, Licia Rivoltini, Marina Radrizzani, Filiberto Belli, Gianalfredo Sciorelli, Fernando Ravagnani, Andrew R. Galazka, Natale Cascinelli, and Giorgio Parmiani
Cancer Res 1989 49: 5230-5234. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1989 49: 5235-5236. [PDF]  

Erratum:

Human Monoclonal Antibodies to Glycolipids and Other Carbohydrate Antigens: Dissection of the Humoral Immune Response in Cancer Patients

Cancer Res 1989 49: 5236 [PDF]  

Experimental Therapy of Human Breast Tumors with ¹³¹I-labeled Monoclonal Antibodies Prepared against the Human Milk Fat Globule

Cancer Res 1989 49: 5236 [PDF]  

Reversible Suppression of c-myc Expression in a Human Colon Carcinoma Line by the Anticancer Agent N-Methylformamide

Cancer Res 1989 49: 5236 [PDF]  

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