REVIEWS:

Blood Flow, Oxygen and Nutrient Supply, and Metabolic Microenvironment of Human Tumors: A Review

Peter Vaupel, Friedrich Kallinowski, and Paul Okunieff
Cancer Res 1989 49: 6449-6465. [Abstract] [PDF]  

Basic Sciences:

Expression of UDP-GalNAc:NeuAc2,3Galß-R ß1,4(GalNAc to Gal) N-Acetylgalactosaminyltransferase Involved in the Synthesis of Sd^a Antigen in Human Large Intestine and Colorectal Carcinomas

Nadia Malagolini, Fabio Dall'Olio, Giuseppina Di Stefano, Francesco Minni, Domenico Marrano, and Franca Serafini-Cessi
Cancer Res 1989 49: 6466-6470. [Abstract] [PDF]  

Prevention and Treatment of Primary Intestinal Tumors in Rats by Piroxicam

Morris Pollard and Phyllis H. Luckert
Cancer Res 1989 49: 6471-6473. [Abstract] [PDF]  

Amplification of Protooncogenes in Surgical Specimens of Human Lung Carcinomas

Masahiko Shiraishi, Masayuki Noguchi, Yukio Shimosato, and Takao Sekiya
Cancer Res 1989 49: 6474-6479. [Abstract] [PDF]  

Decreased Accessibility of Globotriaosylceramide Associated with Decreased Tumorigenicity in Burkitt's Lymphoma Variants Induced by Immunoselection

Simone Junqua, Annette K. Larsen, Pierre Wils, Zohar Mishal, Joëlle Wiels, and Jean-Bernard Le Pecq
Cancer Res 1989 49: 6480-6486. [Abstract] [PDF]  

Induction of Lymphokine-activated Killer Activity by Interleukin 4 in Human Lymphocytes Preactivated by Interleukin 2 in Vivo or in Vitro

Carl M. Higuchi, John A. Thompson, Catherine G. Lindgren, Steven Gillis, Michael B. Widmer, Donald E. Kern, and Alexander Fefer
Cancer Res 1989 49: 6487-6492. [Abstract] [PDF]  

Isolation and Characterization of a Hepatoma-associated Abnormal (Des--carboxy)prothrombin

Howard A. Liebman
Cancer Res 1989 49: 6493-6497. [Abstract] [PDF]  

Differential Metabolism of 9-ß-D-Arabinofuranosylguanine in Human Leukemic Cells

Donna S. Shewach and Beverly S. Mitchell
Cancer Res 1989 49: 6498-6502. [Abstract] [PDF]  

Relationships among Benzo(a)pyrene Metabolism, Benzo(a)pyrene-diolepoxide:DNA Adduct Formation, and Sister Chromatid Exchanges in Human Lymphocytes from Smokers and Nonsmokers

Claudia L. Thompson, Zadock McCoy, Jane M. Lambert, Maria J. Andries, and George W. Lucier
Cancer Res 1989 49: 6503-6511. [Abstract] [PDF]  

Changes in Estrogen Receptor, DNA Ploidy, and Estrogen Metabolism in Rat Hepatocytes during a Two-Stage Model for Hepatocarcinogenesis Using 17-Ethinylestradiol as the Promoting Agent

A. E. M. Vickers, K. Nelson, Z. McCoy, and G. W. Lucier
Cancer Res 1989 49: 6512-6520. [Abstract] [PDF]  

Schedule Dependency of the Antitumor Activity and Toxicity of Polyethylene Glycol-modified Interleukin 2 in Murine Tumor Models

Robert J. Zimmerman, Sharon Lea Aukerman, Nandini V. Katre, Jeffrey L. Winkelhake, and John D. Young
Cancer Res 1989 49: 6521-6528. [Abstract] [PDF]  

Synthesis of a Duplex Oligonucleotide Containing a Nitrogen Mustard Interstrand DNA-DNA Cross-Link

Joshua O. Ojwang, Dorre A. Grueneberg, and Edward L. Loechler
Cancer Res 1989 49: 6529-6537. [Abstract] [PDF]  

Modulation of Ovarian Carcinoma Tumor Marker CA-125 by -Interferon

Christian Marth, Lothar C. Fuith, Günther Böck, Günter Daxenbichler, and Otto Dapunt
Cancer Res 1989 49: 6538-6542. [Abstract] [PDF]  

An Exponential-Gompertzian Description of LoVo Cell Tumor Growth from in Vivo and in Vitro Data

Romano Demicheli, Roberto Foroni, Antonella Ingrosso, Graziella Pratesi, Carla Soranzo, and Monica Tortoreto
Cancer Res 1989 49: 6543-6546. [Abstract] [PDF]  

Kinetic Properties of Mitochondrial H⁺-Adenosine Triphosphatase in Morris Hepatoma 3924A

Ferdinando Capuano, Riccardo Stefanelli, Emanuela Carrieri, and Sergio Papa
Cancer Res 1989 49: 6547-6550. [Abstract] [PDF]  

Lack of Evidence for Aromatase in Human Prostatic Tissues: Effects of 4-Hydroxyandrostenedione and Other Inhibitors on Androgen Metabolism

A. M. H. Brodie, C. Son, D. A. King, K. M. Meyer, and S. E. Inkster
Cancer Res 1989 49: 6551-6555. [Abstract] [PDF]  

Multidrug Resistance in a Human Leukemic Cell Line Selected for Resistance to Trimetrexate

Hadara Arkin, Takao Ohnuma, Barton A. Kamen, James F. Holland, and Shanker Vallabhajosula
Cancer Res 1989 49: 6556-6561. [Abstract] [PDF]  

Depletion of T-Cells with the CD4+CD45R+ Phenotype in Lymphocytes That Infiltrate Subcutaneous Metastases of Human Melanoma

Gaetano Cardi, Michael J. Mastrangelo, and David Berd
Cancer Res 1989 49: 6562-6565. [Abstract] [PDF]  

Proliferation of the Human Colon Carcinoma Cell Line HT29: Autocrine Growth and Deregulated Expression of the c-myc Oncogene

Marie-Elisabeth Forgue-Lafitte, Anne-Marie Coudray, Bernadette Bréant, and Ján Mester
Cancer Res 1989 49: 6566-6571. [Abstract] [PDF]  

Loss of Heterozygosity for Loci on Chromosome 17p in Human Malignant Astrocytoma

Dan Fults, Richard H. Tippets, Gregory A. Thomas, Yusuke Nakamura, and Ray White
Cancer Res 1989 49: 6572-6577. [Abstract] [PDF]  

Heat- or Stress-inducible Transformation-associated Cell Surface Antigen on the Activated H-ras Oncogene-transfected Rat Fiborblast

Arimitsu Konno, Noriyuki Sato, Atsuhito Yagihashi, Toshihiko Torigoe, Junmun Cho, Katsuji Torimoto, Isao Hara, Yoshimasa Wada, Mamoru Okubo, Nobuaki Takahashi, and Kokichi Kikuchi
Cancer Res 1989 49: 6578-6582. [Abstract] [PDF]  

Effect of the Metal Chelating Agent o-Phenanthroline on the DNA and Chromosome Damage Induced by Bleomycin in Chinese Hamster Ovary Cells

Marcelo L. Larramendy, Daniel López-Larraza, Lidia Vidal-Rioja, and Néstor O. Bianchi
Cancer Res 1989 49: 6583-6586. [Abstract] [PDF]  

Immunomodulation by Various Nitrosoureas and Its Effect on the Survival of the Murine Host Bearing a Syngeneic Tumor

Mitzi Nagarkatti, Denise M. Toney, and Prakash S. Nagarkatti
Cancer Res 1989 49: 6587-6592. [Abstract] [PDF]  

Phosphorylation of 3-Deazaguanosine by Nicotinamide Riboside Kinase in Chinese Hamster Ovary Cells

Priscilla P. Saunders, Mei-Tao Tan, Christy D. Spindler, and Roland K. Robins
Cancer Res 1989 49: 6593-6599. [Abstract] [PDF]  

Antimutagenic Effects of Taurine in a Bacterial Assay System

Stewart A. Laidlaw, Marian F. Dietrich, Maria P. Lamtenzan, Hernan I. Vargas, Jerome B. Block, and Joel D. Kopple
Cancer Res 1989 49: 6600-6604. [Abstract] [PDF]  

Amplification, Overexpression, and Rearrangement of the erbB-2 Protooncogene in Primary Human Stomach Carcinomas

Joo-Bae Park, Johng S. Rhim, Sang-Chul Park, Seung-Won Kimm, and Matthias H. Kraus
Cancer Res 1989 49: 6605-6609. [Abstract] [PDF]  

Circadian Variation of 5-Fluorouracil Catabolism in Isolated Perfused Rat Liver

Barry E. Harris, Ruiling Song, Seng-jaw Soong, and Robert B. Diasio
Cancer Res 1989 49: 6610-6614. [Abstract] [PDF]  

In Vitro Pharmacodynamic Assay for Cancer Drug Development: Application to Crisnatol, a New DNA Intercalator

David J. Adams
Cancer Res 1989 49: 6615-6620. [Abstract] [PDF]  

Immunochemical and Biochemical Characterizations of Two Monoclonal Antibody-reacting Antigens Associated with Human Bladder Carcinoma

Duan-sun Zhang and Chi-Wei Lin
Cancer Res 1989 49: 6621-6628. [Abstract] [PDF]  

Diethyldithiocarbamate Modulation of Murine Bone Marrow Toxicity Induced by cis-Diammine(cyclobutanedicarboxylato)platinum(II)

Therese K. Schmalbach and Richard F. Borch
Cancer Res 1989 49: 6629-6633. [Abstract] [PDF]  

Protein Kinase C in Adriamycin Action and Resistance in Mouse Sarcoma 180 Cells

James Posada, Paul Vichi, and Thomas R. Tritton
Cancer Res 1989 49: 6634-6639. [Abstract] [PDF]  

Gene Activation by Induced DNA Rearrangements

Lowell E. Schnipper, Victor Chan, John Sedivy, Parmjit Jat, and Phillip A. Sharp
Cancer Res 1989 49: 6640-6644. [Abstract] [PDF]  

Five New Epitope-defined Monoclonal Antibodies Reactive with G_M2 and Human Glioma and Medulloblastoma Cell Lines

Fotios D. Vrionis, Carol J. Wikstrand, Pam Fredman, Jan-Eric Månsson, Lars Svennerholm, and Darell D. Bigner
Cancer Res 1989 49: 6645-6651. [Abstract] [PDF]  

Macrophage-mediated Induction of DNA Strand Breaks in Target Tumor Cells

Yen C. Chong, Gloria H. Heppner, Leslie A. Paul, and Amy M. Fulton
Cancer Res 1989 49: 6652-6657. [Abstract] [PDF]  

Potentiation of Nitrogen Mustard Cytotoxicity by Disulfiram, Diethyldithiocarbamic Acid, and Diethylamine in Mice

Frederick Valeriote and Harry E. Grates
Cancer Res 1989 49: 6658-6661. [Abstract] [PDF]  

Generation of a Lipid-like Cytotoxin from Human CD16+ Natural Killer Cells

Louis M. Cosentino and Martha K. Cathcart
Cancer Res 1989 49: 6662-6669. [Abstract] [PDF]  

Mechanisms of Estrogen Action on the Proliferation of MCF-7 Human Breast Cancer Cells in an Improved Culture Medium

Yoshihiko Furuya, Norio Kohno, Yoshisada Fujiwara, and Yoichi Saitoh
Cancer Res 1989 49: 6670-6674. [Abstract] [PDF]  

Genetic Alterations of c-myc, c-erbB-2, and c-Ha-ras Protooncogenes and Clinical Associations in Human Breast Carcinomas

Irène Garcia, Pierre-Yves Dietrich, Matti Aapro, Geneviève Vauthier, Lucien Vadas, and Eric Engel
Cancer Res 1989 49: 6675-6679. [Abstract] [PDF]  

Polyamine Oxidation, Programmed Cell Death, and Regulation of Melanoma in the Murine Embryonic Limb

Ralph E. Parchment and G. Barry Pierce
Cancer Res 1989 49: 6680-6686. [Abstract] [PDF]  

Inhibition of a Transplantable Pancreatic Carcinoma by Castration and Estradiol Administration in Rats

Chiyo Sumi, Truls Brinck-Johnsen, and Daniel S. Longnecker
Cancer Res 1989 49: 6687-6692. [Abstract] [PDF]  

Correlation of Phorbol Ester Promotion in the Resistant C57BL/6J Mouse with Sustained Hyperplasia but not Ornithine Decarboxylase or Protein Kinase C

Susan M. Fischer, Daniel W. Jasheway, Richard C. Klann, Andrew P. Butler, Kelly E. Patrick, James K. Baldwin, and Gregory S. Cameron
Cancer Res 1989 49: 6693-6699. [Abstract] [PDF]  

Detection of Transforming Growth Factor- Messenger RNA in Normal and Chemically Transformed Hamster Oral Epithelium by in Situ Hybridization

Long-Chang Chang, Ming Yung Chou, Phoebe Chow, Karekine Matossian, Jim McBride, Tao Chiang, George T. Gallagher, and David T. W. Wong
Cancer Res 1989 49: 6700-6707. [Abstract] [PDF]  

Expression of Neurofilaments in a Neoplastic Human Salivary Intercalated Duct Cell Line or Its Derivatives and Effect of Nerve Growth Factor on the Cellular Proliferation and Phenotype

Hiroki Iga, Masayuki Azuma, Shinichi Nagamine, Ryoji Kaji, Masahiro Takase, Tetsuo Yanagawa, Hideo Yoshida, and Mitsunobu Sato
Cancer Res 1989 49: 6708-6719. [Abstract] [PDF]  

Identification by Monoclonal Antibodies of an Antigen Shed by Human Bladder Cancer Cells

Monica Liebert, Gary A. Wedemeyer, Judith A. Stein, Raymond W. Washington, Jr., Andrew Flint, Liqin Ren, and H. Barton Grossman
Cancer Res 1989 49: 6720-6726. [Abstract] [PDF]  

Antitumor Effects of an Antiangiogenic Polysaccharide from an Arthrobacter Species with or without a Steroid

Noriko G. Tanaka, Noritsugu Sakamoto, Kazuhiro Inoue, Hiroshi Korenaga, Shizuo Kadoya, Hidemasa Ogawa, and Yasuaki Osada
Cancer Res 1989 49: 6727-6730. [Abstract] [PDF]  

Model for the Formation of Double Minutes from Prematurely Condensed Chromosomes of Replicating Micronuclei in Drug-treated Chinese Hamster Ovary Cells Undergoing DNA Amplification

Subrata Sen, Walter N. Hittelman, Larry D. Teeter, and M. Tien Kuo
Cancer Res 1989 49: 6731-6737. [Abstract] [PDF]  

High Invasiveness Associated with Augmentation of Motility in a fos-transferred Highly Metastatic Rat 3Y1 Cell Line

Shun'ichiro Taniguchi, Masaaki Tatsuka, Kohji Nakamatsu, Mitsuse Inoue, Hiroyuki Sadano, Hiroshi Okazaki, Hideyuki Iwamoto, and Tsuneo Baba
Cancer Res 1989 49: 6738-6744. [Abstract] [PDF]  

Differentiation of Human Variant Small Cell Lung Cancer Cell Lines to a Classic Morphology by Retinoic Acid

L. Austin Doyle, Dennis Giangiulo, Arif Hussain, Hyo-Jong Park, Ray-Whay Chiu Yen, and Michael Borges
Cancer Res 1989 49: 6745-6751. [Abstract] [PDF]  

Establishment and Characterization of a Tumor Cell Line from Human Nasopharyngeal Carcinoma Tissue

Yu-Sun Chang, Su-Yu Lin, Pey-Fen Lee, Tim Durff, Ho-Chin Chung, and Min-Shiu Tsai
Cancer Res 1989 49: 6752-6757. [Abstract] [PDF]  

Reversal of Enzymic Phenotype of Thymidine Metabolism in Induced Differentiation of U-937 Cells

Taiichi Shiotani, Yasuko Hashimoto, Jiro Fujita, Noriko Yamauchi, Yasufumi Yamaji, Hitoyasu Futami, Masami Bungo, Hiroyuki Nakamura, Terukazu Tanaka, and Shozo Irino
Cancer Res 1989 49: 6758-6763. [Abstract] [PDF]  

Identification and Characterization of a M_r 50,000 Adrenal Protein in Human Hepatocellular Carcinoma

Mehmet Ozturk, Philippe Motté, Hiroshi Takahashi, Mark Frohlich, Byron Wilson, Linda Hill, Brigitte Bressac, and Jack R. Wands
Cancer Res 1989 49: 6764-6773. [Abstract] [PDF]  

Analysis of a Mouse Monoclonal Antibody That Reacts with a Specific Region of the Human Proximal Tubule and Subsets Renal Cell Carcinomas

N.H. Bander, C.L. Finstad, C. Cordon-Cardo, R.D. Ramsawak, E.D. Vaughan, Jr., W.F. Whitmore, Jr., H.F. Oettgen, M.R. Melamed, and L.J. Old
Cancer Res 1989 49: 6774-6780. [Abstract] [PDF]  

Amplification, Rearrangements, and Enhanced Expression of c-myc in Chemically Induced Rat Liver Tumors in Vivo and in Vitro

Bernhard K. Suchy, Marina Sarafoff, Rosi Kerler, and Hartmut M. Rabes
Cancer Res 1989 49: 6781-6787. [Abstract] [PDF]  

Detection of an Altered Form of Cell-CAM 105 on Rat Transplantable and Primary Hepatocellular Carcinomas

Douglas C. Hixson and Kerry D. McEntire
Cancer Res 1989 49: 6788-6794. [Abstract] [PDF]  

Comparison of the Structural Characteristics of Cell-CAM 105 from Hepatocytes with Those of an Altered Form Expressed by Rat Transplantable Hepatocellular Carcinomas

Kerry D. McEntire, Jeanette Mowery, and Douglas C. Hixson
Cancer Res 1989 49: 6795-6802. [Abstract] [PDF]  

Influence of Esophagojejunostomy on the Induction of Adenocarcinoma of the Distal Esophagus in Sprague-Dawley Rats by Subcutaneous Injection of 2,6-Dimethylnitrosomorpholine

Manuel Pera, Antonio Cardesa, Jose A. Bombi, Heinrich Ernst, Cristobal Pera, and Ulrich Mohr
Cancer Res 1989 49: 6803-6808. [Abstract] [PDF]  

Biochemical Properties of Media Conditioned by Simian Virus 40-induced Hamster Tumor Cells: Correlation with Distinct Cell Phenotypes but not with Oncogenicity

M. Carbone, E. Kajiwara, C.T. Patch, A.M. Lewis, Jr., A. S. Levine, and K. Dixon
Cancer Res 1989 49: 6809-6812. [Abstract] [PDF]  

Genetic Control of Susceptibility to Diethylnitrosamine Carcinogenesis in Inbred ACP (grc⁺) and R16 (grc) Rats

Mona F. Melhem, K. N. Rao, Heinz W. Kunz, Mary Kazanecki, and Thomas J. Gill, III
Cancer Res 1989 49: 6813-6821. [Abstract] [PDF]  

Clinical and Epidemiological Investigations:

Role of Endoscopy in the Diagnosis of Cancer: A Consensus Statement Prepared by a Working Party of the International Union against Cancer

Richard H. Hunt, Peter B. Cotton, Massimo Crespi, Joseph R. Drago, Keiichi Kawai, Rene Lambert, Charles J. Lightdale, David R. Sanderson, and Giles W. Stevenson
Cancer Res 1989 49: 6822-6827. [PDF]  

Association of Incident Carcinoma of the Endometrium with Body Weight and Fat Distribution in Older Women: Early Findings of the Iowa Women's Health Study

Aaron R. Folsom, Susan A. Kaye, John D. Potter, and Ronald J. Prineas
Cancer Res 1989 49: 6828-6831. [Abstract] [PDF]  

Repetitive Weekly Cycles of Interleukin 2: Effect of Outpatient Treatment with a Lower Dose of Interleukin 2 on Non-Major Histocompatibility Complex-restricted Killer Activity

D. Goldstein, J. A. Sosman, J. A. Hank, G. Weil-Hillman, K. H. Moore, A. Borchert, R. Bechhofer, B. Storer, P. C. Kohler, D. Levitt, and P. M. Sondel
Cancer Res 1989 49: 6832-6839. [Abstract] [PDF]  

Flow Cytometric Determination of the Frequency and Heterogeneity of Expression of Human Melanoma-associated Antigens

David Berd, Meenhard Herlyn, Hilary Koprowski, and Michael J. Mastrangelo
Cancer Res 1989 49: 6840-6844. [Abstract] [PDF]  

Identification and Measurement of Calcitonin Precursors in Serum of Patients with Malignant Diseases

Pascale P. Ghillani, Philippe Motté, Frédéric Troalen, Annick Jullienne, Paule Gardet, Thierry Le Chevalier, Philippe Rougier, Martin Schlumberger, Claude Bohuon, and Dominique Bellet
Cancer Res 1989 49: 6845-6851. [Abstract] [PDF]  

Meeting Report:

Molecular Aspects of Growth Control: An Extended Report on the First Joint Meeting of the AACR and the Japanese Cancer Association

Garth Anderson, Enrico Mihich, Susumu Nishimura, Masaaki Terada, and Takashi Sugimura
Cancer Res 1989 49: 6852-6866. [PDF]  

Articles:

Announcements

Cancer Res 1989 49: 6867-6868. [PDF]  

Erratum:

DNA Topoisomerase I-mediated DNA Cleavage and Cytotoxicity of Camptothecin Analogues

Cancer Res 1989 49: 6868 [PDF]  

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