Basic Sciences:

Use of Primary Cultures of Human Hepatocytes in Toxicology Studies

Byron E. Butterworth, Tracey Smith-Oliver, Lynn Earle, David J. Loury, Russell D. White, David J. Doolittle, Peter K. Working, Russell C. Cattley, Randy Jirtle, George Michalopoulos, and Stephen Strom
Cancer Res 1989 49: 1075-1084. [Abstract] [PDF]  

5-Fluoropyrimidine-induced DNA Damage in Human Colon Adenocarcinoma and Its Augmentation by the Nucleoside Transport Inhibitor Dipyridamole

Ulf Lönn, Sigrid Lönn, Urban Nylen, and Gerard Winblad
Cancer Res 1989 49: 1085-1089. [Abstract] [PDF]  

Behavior of Activities of Thymidine Metabolizing Enzymes in Human Leukemia-Lymphoma Cells

Taiichi Shiotani, Yasuko Hashimoto, Terukazu Tanaka, and Shozo Irino
Cancer Res 1989 49: 1090-1094. [Abstract] [PDF]  

Frequent Loss of Heterozygosity on Chromosome 14q in Neuroblastoma

Takashi Suzuki, Jun Yokota, Hideo Mugishima, Ikuo Okabe, Masahiko Ookuni, Takashi Sugimura, and Masaaki Terada
Cancer Res 1989 49: 1095-1098. [Abstract] [PDF]  

In Vitro Activity of Bleomycin, Tallysomycin S10b, and Liblomycin against Fresh Human Tumor Cells

Elias A. Tueni, Robert A. Newman, Fraser L. Baker, Jaffer A. Ajani, Dominic Fan, and Gary Spitzer
Cancer Res 1989 49: 1099-1102. [Abstract] [PDF]  

Infrequent Activation of K-ras, H-ras, and Other Oncogenes in Hepatocellular Neoplasms Initiated by Methyl(acetoxymethyl)nitrosamine, a Methylating Agent, and Promoted by Phenobarbital in F344 Rats

Masahiro Watatani, Alan O. Perantoni, Carl D. Reed, Takayuki Enomoto, Martin L. Wenk, and Jerry M. Rice
Cancer Res 1989 49: 1103-1109. [Abstract] [PDF]  

Novobiocin- and Phorbol-12-myristate-13-acetate-induced Differentiation of Human Leukemia Cells Associated with a Reduction in Topoisomerase II Activity

Andreas Constantinou, Cynthia Henning-Chubb, and Eliezer Huberman
Cancer Res 1989 49: 1110-1117. [Abstract] [PDF]  

Cellular Consequences of Overproduction of DNA Topoisomerase II in an Ataxia-Telangiectasia Cell Line

P. J. Smith and T. A. Makinson
Cancer Res 1989 49: 1118-1124. [Abstract] [PDF]  

Modulation of Lymphocyte Proliferation and Immunoglobulin Production by Transferrin-Gallium

Christopher R. Chitambar, Margaret C. Seigneuret, William G. Matthaeus, and Lawrence G. Lum
Cancer Res 1989 49: 1125-1129. [Abstract] [PDF]  

Epidermal Growth Factor Receptor Protein-Tyrosine Kinase Activity in Human Cell Lines Established from Squamous Carcinomas of the Head and Neck

Steve A. Maxwell, Peter G. Sacks, Jordan U. Gutterman, and Gary E. Gallick
Cancer Res 1989 49: 1130-1137. [Abstract] [PDF]  

Inhibition of U937 Eicosanoid and DNA Synthesis by 5,8,11,14-Eicosatetraynoic Acid, an Inhibitor of Arachidonic Acid Metabolism and Its Partial Reversal by Leukotriene C₄

Frank Ondrey, Jules E. Harris, and Kenning M. Anderson
Cancer Res 1989 49: 1138-1142. [Abstract] [PDF]  

Autocrine Stimulation of Interleukin 1 in the Growth of Adult Human T-Cell Leukemia Cells

Fumihiko Shirakawa, Yoshiya Tanaka, Susumu Oda, Sumiya Eto, and Uki Yamashita
Cancer Res 1989 49: 1143-1147. [Abstract] [PDF]  

Phenotypic Instability of Drug Sensitivity in a Human Colon Carcinoma Cell Line

Peter J. Ferguson and Yung-chi Cheng
Cancer Res 1989 49: 1148-1153. [Abstract] [PDF]  

Involvement of Both Tac and Non-Tac Interleukin 2-binding Peptides in the Interleukin 2-dependent Proliferation of Human Tumor-infiltrating Lymphocytes

Masato Yagita, Kyogo Itoh, Mitsuru Tsudo, Laurie B. Owen Schaub, Chris D. Platsoucas, Charles M. Balch, and Elizabeth A. Grimm
Cancer Res 1989 49: 1154-1159. [Abstract] [PDF]  

Effect of Cancer on the in Vivo Energy State of Rat Liver and Skeletal Muscle

Alison L. Schneeberger, R. Terry Thompson, Albert A. Driedger, Richard J. Finley, and Richard I. Inculet
Cancer Res 1989 49: 1160-1164. [Abstract] [PDF]  

Effects of Host Hormonal Status on Binding of Activated Estrogen Receptor to Nuclei from R3230AC and 7,12-Dimethylbenz[a]anthracene-induced Mammary Tumors

Carolyn M. Klinge, Robert A. Bambara, Sayeeda Zain, and Russell Hilf
Cancer Res 1989 49: 1165-1170. [Abstract] [PDF]  

³²P-Postlabeling Analysis of DNA Adducts in Liver of Wild English Sole (Parophrys vetulus) and Winter Flounder (Pseudopleuronectes americanus)

Usha Varanasi, William L. Reichert, and John E. Stein
Cancer Res 1989 49: 1171-1177. [Abstract] [PDF]  

Effects of Oral Administration of Sulfolithocholic Acid Disodium Salt and Lithocholic Acid Sodium Salt on N-Methyl-N-nitrosourea-induced Colonic Tumorigenesis in Conventional Rats

Noritoshi Tanida, Kenji Sawada, Akihiko Kawaura, Makoto Oda, Takashi Shimoyama, and Tomio Narisawa
Cancer Res 1989 49: 1178-1181. [Abstract] [PDF]  

Antitumor Activity of 2-Chloroethyl (Methylsulfonyl)methanesulfonate (Clomesone, NSC 338947) against Selected Tumor Systems in Mice

Donald J. Dykes, William R. Waud, Steadman D. Harrison, Jr., W. Russell Laster, Jr., Daniel P. Griswold, Jr., Y. Fulmer Shealy, and John A. Montgomery
Cancer Res 1989 49: 1182-1186. [Abstract] [PDF]  

Human and Rat Kidney Cell Metabolism of 2-Acetylaminofluorene and Benzo(a)pyrene

Kenneth M. Rudo, W. C. Dauterman, and Robert Langenbach
Cancer Res 1989 49: 1187-1192. [Abstract] [PDF]  

Protection by Cycloheximide against Cytotoxicity Induced by Vincristine, Colchicine, or ¹²-Prostaglandin J₂ on Human Osteosarcoma Cells

Toshiyuki Sakai, Akira Aoike, Nobuyuki Marui, Keiichi Kawai, Hoyoku Nishino, and Masanori Fukushima
Cancer Res 1989 49: 1193-1196. [Abstract] [PDF]  

Effect of Retinoic Acid on DNA Cleavage and Cytotoxicity of Topoisomerase II-reactive Drugs in a Human Head and Neck Squamous Carcinoma Cell Line

Hoon-Kyo Kim, Leonard A. Zwelling, Peter G. Sacks, Waun Ki Hong, Diana Chan, Lynn Silberman, and Bonnie S. Glisson
Cancer Res 1989 49: 1197-1201. [Abstract] [PDF]  

Tumor Copromoting Activity of -Interferon in the Murine Skin Multistage Carcinogenesis Model

John J. Reiners, Jr., Tim Rupp, Alan Colby, Amador R. Cantu, and Amy Pavone
Cancer Res 1989 49: 1202-1206. [Abstract] [PDF]  

Specificity of Antigens on UV Radiation-induced Antigenic Tumor Cell Variants Measured in Vitro and in Vivo

Lisa W. Hostetler, Cynthia A. Romerdahl, and Margaret L. Kripke
Cancer Res 1989 49: 1207-1213. [Abstract] [PDF]  

Genetic Control of Resistance to 3-Methylcholanthrene-induced T-Cell Lymphoma in Mice

Sally T. Ishizaka and Frank Lilly
Cancer Res 1989 49: 1214-1219. [Abstract] [PDF]  

Allele Loss at the c-Ha-ras1 Locus in Human Ovarian Cancer

Je Ho Lee, John J. Kavanagh, J. Taylor Wharton, David M. Wildrick, and Mark Blick
Cancer Res 1989 49: 1220-1222. [Abstract] [PDF]  

Activated Oncogenes in Human Skin Tumors from a Repair-deficient Syndrome, Xeroderma Pigmentosum

Horacio G. Suarez, Leela Daya-Grosjean, Daniel Schlaifer, Pierre Nardeux, Georges Renault, Johannes L. Bos, and Alain Sarasin
Cancer Res 1989 49: 1223-1228. [Abstract] [PDF]  

Establishment and Characterization of a Melanoma Cell Line from a Xeroderma Pigmentosum Patient: Activation of N-ras at a Potential Pyrimidine Dimer Site

W. Keijzer, M. P. Mulder, J. C. M. Langeveld, E. M. E. Smit, J. L. Bos, D. Bootsma, and J. H. J. Hoeijmakers
Cancer Res 1989 49: 1229-1235. [Abstract] [PDF]  

Foci of Aberrant Crypts in the Colons of Mice and Rats Exposed to Carcinogens Associated with Foods

Barbara Tudek, Ranjana P. Bird, and W. Robert Bruce
Cancer Res 1989 49: 1236-1240. [Abstract] [PDF]  

Presence of a Constitutive Paracrine ß-Interferon in v-mos-bearing Nonmalignant Reverted Cells

J. Gerfaux, D. Sergiescu, J-G. Fournier, F. Pochart, A-M. Joret, and C. Chany
Cancer Res 1989 49: 1241-1246. [Abstract] [PDF]  

Effects of Estradiol on Prolactin and Growth Hormone Messenger RNAs in Cultured Normal and Neoplastic (MtT/W15 and GH₃) Rat Pituitary Cells

Jiangyue Song, Long Jin, and Ricardo V. Lloyd
Cancer Res 1989 49: 1247-1253. [Abstract] [PDF]  

Effects of Hyperthermia on Chromatin Condensation and Nucleoli Disintegration as Visualized by Induction of Premature Chromosome Condensation in Interphase Mammalian Cells

George E. Iliakis and Gabriel E. Pantelias
Cancer Res 1989 49: 1254-1260. [Abstract] [PDF]  

Biochemical and Immunological Characterization of K-1735P Melanoma Galactoside-binding Lectins and Their Modulation by Differentiation Inducers

Reuben Lotan, Dunia Carralero, Dafna Lotan, and Avraham Raz
Cancer Res 1989 49: 1261-1268. [Abstract] [PDF]  

Analysis of the Antigenic Profile of Uveal Melanoma Lesions with Anti-Cutaneous Melanoma-associated Antigen and Anti-HLA Monoclonal Antibodies

P. G. Natali, A. Bigotti, M. R. Nicotra, R. M. Nardi, A. Delovu, O. Segatto, and S. Ferrone
Cancer Res 1989 49: 1269-1274. [Abstract] [PDF]  

Nonrandom Rearrangement of Chromosome 14 at Band q32.33 in Human Lymphoid Malignancies with Mature B-Cell Phenotype

Kazuhiro Nishida, Masafumi Taniwaki, Shinichi Misawa, and Tatsuo Abe
Cancer Res 1989 49: 1275-1281. [Abstract] [PDF]  

Specific Cytogenetic Abnormalities in Two New Human Colorectal Adenomaderived Epithelial Cell Lines

Christos Paraskeva, Susan Finerty, Richard A. Mountford, and Susan C. Powell
Cancer Res 1989 49: 1282-1286. [Abstract] [PDF]  

Varied Differentiation Responses of Human Leukemias to Bryostain 1

Andrew S. Kraft, Felicia William, George R. Pettit, and Michael B. Lilly
Cancer Res 1989 49: 1287-1293. [Abstract] [PDF]  

Antigenic Differences between Metastatic and Nonmetastatic BSp73 Rat Tumor Variants Characterized by Monoclonal Antibodies

Siegfried Matzku, Achim Wenzel, Sida Liu, and Margot Zöller
Cancer Res 1989 49: 1294-1299. [Abstract] [PDF]  

Immunohistological Detection of Fucosyl-G_m1 Ganglioside in Human Lung Cancer and Normal Tissues with Monoclonal Antibodies

Fred-Thomas Brezicka, Sante Olling, Olle Nilsson, Jonas Bergh, Jan Holmgren, Sverre Sörenson, Fridrik Yngvason, and Leif Lindholm
Cancer Res 1989 49: 1300-1305. [Abstract] [PDF]  

Clinical and Epidemiological Investigations:

Dose-related Endocrine Effects and Pharmacokinetics of Oral and Intramuscular 4-Hydroxyandrostenedione in Postmenopausal Breast Cancer Patients

M. Dowsett, D. C. Cunningham, R. C. Stein, S. Evans, L. Dehennin, A. Hedley, and R. C. Coombes
Cancer Res 1989 49: 1306-1312. [Abstract] [PDF]  

Characterization of Epidermal Growth Factor Receptor in Primary Human Non-Small Cell Lung Cancer

Dan Veale, Niall Kerr, G. John Gibson, and Adrian L. Harris
Cancer Res 1989 49: 1313-1317. [Abstract] [PDF]  

Plasma Pharmacokinetics of High-Dose Oral Melphalan in Patients Treated with Trialkylator Chemotherapy and Autologous Bone Marrow Reinfusion

Kyung E. Choi, Mark J. Ratain, Stephanie F. Williams, Janet A. Golick, Janet C. Beschorner, Laura J. Fullem, and Jacob D. Bitran
Cancer Res 1989 49: 1318-1321. [Abstract] [PDF]  

Case-Control Study of Colorectal Cancer and Fecapentaene Excretion

Mark H. Schiffman, Roger L. Van Tassell, Adam Robinson, Lee Smith, James Daniel, Robert N. Hoover, Roselyn Weil, Jeanne Rosenthal, Padmanabhan P. Nair, Samuel Schwartz, Hugh Pettigrew, Stephen Curiale, Gerald Batist, Gladys Block, and Tracy D. Wilkins
Cancer Res 1989 49: 1322-1326. [Abstract] [PDF]  

Meeting Report:

Conference on Advances in the Biology and Chemistry of N-Nitroso and Related Compounds

Stephen S. Hecht, Sidney S. Mirvish, Barry Gold, Donald Nagel, and Peter N. Magee
Cancer Res 1989 49: 1327-1329. [PDF]  

Articles:

Announcements

Cancer Res 1989 49: 1330-1331. [PDF]  

Recent Death

Cancer Res 1989 49: 1331 [PDF]  

Calendar of Events

Cancer Res 1989 49: 1331 [PDF]  

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