Articles:

Editorial

Carlo M. Croce
Cancer Res 1990 50: 3469 [PDF]  

Announcements

Cancer Res 1990 50: 3807 [PDF]  

Public Issues:

Where Have Traditional Competing RO1 Grants Gone?

Samuel Broder and John Hartinger
Cancer Res 1990 50: 3470-3472. [PDF]  

REVIEWS:

Antineoplastic Activity of the Combination of Interferon and Cytotoxic Agents against Experimental and Human Malignancies: A Review

Scott Wadler and Edward L. Schwartz
Cancer Res 1990 50: 3473-3486. [Abstract] [PDF]  

Basic Sciences:

Interstitial Transport of Rabbit and Sheep Antibodies in Normal and Neoplastic Tissues

Michelle A. Clauss and Rakesh K. Jain
Cancer Res 1990 50: 3487-3492. [Abstract] [PDF]  

Relationship between Dose Rate of [6RS]Leucovorin Administration, Plasma Concentrations of Reduced Folates, and Pools of 5,10-Methylenetetrahydrofolates and Tetrahydrofolates in Human Colon Adenocarcinoma Xenografts

Janet A. Houghton, Larry G. Williams, Siebold S. N. de Graaf, Pamela J. Cheshire, John H. Rodman, Dan C. Maneval, Irving W. Wainer, Philippe Jadaud, and Peter J. Houghton
Cancer Res 1990 50: 3493-3502. [Abstract] [PDF]  

Manipulation of Oxygen Radical-scavenging Capacity in Mice Alters Host Sensitivity to Tumor Necrosis Factor Toxicity but Does Not Interfere with Its Antitumor Efficacy

Gabriel J. Hauser, Joe K. McIntosh, William D. Travis, and Steven A. Rosenberg
Cancer Res 1990 50: 3503-3508. [Abstract] [PDF]  

Invasive and Metastatic Capacity of Revertants of LFA-1-deficient Mutant T-Cell Hybridomas

Folkert F. Roossien, Patricia E. de Kuiper, Diana de Rijk, and Ed Roos
Cancer Res 1990 50: 3509-3513. [Abstract] [PDF]  

Comparative Tissue Distribution in Mice of the -Emitter ²¹¹At and ¹³¹I as Labels of a Monoclonal Antibody and F(ab')₂ Fragment

Pradeep K. Garg, Cary L. Harrison, and Michael R. Zalutsky
Cancer Res 1990 50: 3514-3520. [Abstract] [PDF]  

Calyculin A, an Inhibitor of Protein Phosphatases, a Potent Tumor Promoter on CD-1 Mouse Skin

Masami Suganuma, Hirota Fujiki, Hiroko Furuya-Suguri, Shigeru Yoshizawa, Shigeru Yasumoto, Yuko Kato, Nobuhiro Fusetani, and Takashi Sugimura
Cancer Res 1990 50: 3521-3525. [Abstract] [PDF]  

Characterization of OKT3-initiated Lymphokine-activated Effectors Expanded with Interleukin 2 and Tumor Necrosis Factor

Stephen C. Yang, Laurie B. Owen-Schaub, Jack A. Roth, and Elizabeth A. Grimm
Cancer Res 1990 50: 3526-3532. [Abstract] [PDF]  

Inhibition by Mouse /ß-Interferon of the Multiplication of /ß-Interferon-resistant Friend Erythroleukemia Cells Cocultured with Mouse Hepatocytes

Hiroaki Yasui, Enrico Proietti, Françoise Vignaux, Pierre Eid, and Ion Gresser
Cancer Res 1990 50: 3533-3539. [Abstract] [PDF]  

Antitumor Activity of the Monoclonal Antibody-Vinca Alkaloid Immunoconjugate LY203725 (KS1/4-4-Desacetylvinblastine-3-carboxhydrazide) in a Nude Mouse Model of Human Ovarian Cancer

Lynn D. Apelgren, Dianna L. Zimmerman, Stephen L. Briggs, and Thomas F. Bumol
Cancer Res 1990 50: 3540-3544. [Abstract] [PDF]  

Differential Drug Sensitivity Conferred by Growth Status Detected in a Mixed Population of Cycling and Noncycling Cells

M. H. Barcellos-Hoff, L. J. Marton, and Dennis F. Deen
Cancer Res 1990 50: 3551-3555. [Abstract] [PDF]  

Correlation between Cell Killing by cis-Diamminedichloroplatinum(II) in Six Mammalian Cell Lines and Binding of a cis-Diamminedichloroplatinum(II)-DNA Antiserum

Philippe M. A. B. Terheggen, Joke Y. Emondt, Ben G. J. Floot, Robert Dijkman, Peter I. Schrier, Leo den Engelse, and Adrian C. Begg
Cancer Res 1990 50: 3556-3561. [Abstract] [PDF]  

Persistently Increased Expression of a 3-Methylcholanthrene-inducible Phenol Uridine Diphosphate-Glucuronosyltransferase in Rat Hepatocyte Nodules and Hepatocellular Carcinomas

Karl Walter Bock, Peter A. Münzel, Elke Röhrdanz, Dieter Schrenk, and Lennart C. Eriksson
Cancer Res 1990 50: 3569-3573. [Abstract] [PDF]  

Interaction of Methotrexate Polyglutamates and Dihydrofolate during Leucovorin Rescue in a Human Breast Cancer Cell Line (MCF-7)

Carmen J. Allegra and Donna Boarman
Cancer Res 1990 50: 3574-3578. [Abstract] [PDF]  

Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Related Compounds on the Occupied Nuclear Estrogen Receptor in MCF-7 Human Breast Cancer Cells

M. Harris, T. Zacharewski, and S. Safe
Cancer Res 1990 50: 3579-3584. [Abstract] [PDF]  

Lymphocyte Subset Alterations in Nodes Regional to Human Melanoma

Zohreh Farzad, Alistair J. Cochran, William H. McBride, J. Dixon Gray, Victoria Wong, and Donald L. Morton
Cancer Res 1990 50: 3585-3588. [Abstract] [PDF]  

Modulation of the Production of a Parathyroid Hormone-like Protein in Human Squamous Carcinoma Cell Lines by Interaction with Fibroblasts

Klaas Hoekman, Clemens W. G. M. Lowik, Marjan v. d. Ruit, Johanna Kempenaar, Olav L. M. Bijvoet, and Maria Ponec
Cancer Res 1990 50: 3589-3594. [Abstract] [PDF]  

Production of Diacylglycerol, an Activator of Protein Kinase C, by Human Intestinal Microflora

Masami Morotomi, Jose G. Guillem, Paul LoGerfo, and I. Bernard Weinstein
Cancer Res 1990 50: 3595-3599. [Abstract] [PDF]  

Isolation and Characterization of a Rat Liver Epithelial Cell Line Resistant to the Antiproliferative Effects of Transforming Growth Factor ß (Type 1)

Mrunal S. Chapekar, Anthony C. Huggett, Caroline C. Cheng, Lori L. Hampton, K-H. Lin, and Snorri S. Thorgeirsson
Cancer Res 1990 50: 3600-3604. [Abstract] [PDF]  

Changes in Glutathione Content and Resistance to Anticancer Agents in Human Stomach Cancer Cells Induced by Treatments with Melphalan in Vitro

S. C. Barranco, C. M. Townsend, Jr., B. Weintraub, E. G. Beasley, K. K. MacLean, J. Shaeffer, N. H. Liu, and K. Schellenberg
Cancer Res 1990 50: 3614-3618. [Abstract] [PDF]  

Enhancement of Murine Tumor Cell Sensitivity to Adriamycin by Presentation of the Drug in Phosphatidylcholine-Phosphatidylserine Liposomes

Dominic Fan, Corazon D. Bucana, Catherine A. O'Brian, Leonard A. Zwelling, Christopher Seid, and Isaiah J. Fidler
Cancer Res 1990 50: 3619-3626. [Abstract] [PDF]  

Activation of c-Ki-ras in Human Gastrointestinal Dysplasias Determined by Direct Sequencing of Polymerase Chain Reaction Products

Stephen J. Meltzer, Shrikant M. Mane, Patrick K. Wood, James H. Resau, Carnell Newkirk, John A. Terzakis, Burton I. Korelitz, Wilfred M. Weinstein, and Samuel W. Needleman
Cancer Res 1990 50: 3627-3630. [Abstract] [PDF]  

Inhibition by Sulfated Chitin Derivatives of Invasion through Extracellular Matrix and Enzymatic Degradation by Metastatic Melanoma Cells

Ikuo Saiki, Jun Murata, Motowo Nakajima, Seiichi Tokura, and Ichiro Azuma
Cancer Res 1990 50: 3631-3637. [Abstract] [PDF]  

Reduction of Immunogenicity by Covalent Modification of Murine and Rabbit Immunoglobulins with Oxidized Dextrans of Low Molecular Weight

Roberto Fagnani, Michael S. Hagan, and Richard Bartholomew
Cancer Res 1990 50: 3638-3645. [Abstract] [PDF]  

Synergistic Action of a Plant Rhamnogalacturonan Enhancing Antitumor Cytotoxicity of Human Natural Killer and Lymphokine-activated Killer Cells: Chemical Specificity of Target Cell Recognition

Edgar A. Mueller and F. Alfred Anderer
Cancer Res 1990 50: 3646-3651. [Abstract] [PDF]  

Aromatase Inhibition by an Enzyme-activated Irreversible Inhibitor in Human Carcinoma Cell Cultures

Robert W. Brueggemeier and Nancy E. Katlic
Cancer Res 1990 50: 3652-3656. [Abstract] [PDF]  

Evaluation of Arylmethylaminopropanediols by a Novel in Vitro Pharmacodynamic Assay: Correlation with Antitumor Activity in Vivo

David J. Adams, Pamela J. Watkins, Vincent C. Knick, Richard L. Tuttle, and Kenneth W. Bair
Cancer Res 1990 50: 3663-3669. [Abstract] [PDF]  

Effects of Calcium Antagonists in Multidrug Resistant Primary Human Renal Cell Carcinomas

Gerald H. Mickisch, Jutta Kössig, Gerhard Keilhauer, Erich Schlick, Reinhold K. Tschada, and Peter M. Alken
Cancer Res 1990 50: 3670-3674. [Abstract] [PDF]  

Modulatory Activity of 2',2'-Difluorodeoxycytidine on the Phosphorylation and Cytotoxicity of Arabinosyl Nucleosides

Varsha Gandhi and William Plunkett
Cancer Res 1990 50: 3675-3680. [Abstract] [PDF]  

Evaluation of Tetrazolium-based Semiautomatic Colorimetric Assay for Measurement of Human Antitumor Cytotoxicity

Dae Seog Heo, Jae-Gahb Park, Kensaku Hata, Roger Day, Ronald B. Herberman, and Theresa L. Whiteside
Cancer Res 1990 50: 3681-3690. [Abstract] [PDF]  

A Somatostatin-secreting Cell Line Established from a Human Pancreatic Islet Cell Carcinoma (Somatostatinoma): Release Experiment and Immunohistochemical Study

Haruo Iguchi, Itsuro Hayashi, and Akira Kono
Cancer Res 1990 50: 3691-3693. [Abstract] [PDF]  

ß₂-Microglobulin Expression in Human Embryonal Neuroblastoma Reflects Its Developmental Regulation

Mark J. Cooper, Grover M. Hutchins, Robert J. Mennie, and Mark A. Israel
Cancer Res 1990 50: 3694-3700. [Abstract] [PDF]  

Tumor Promotion by the Peroxisome Proliferator Nafenopin Involving a Specific Subtype of Altered Foci in Rat Liver

Bettina Kraupp-Grasl, Wolfgang Huber, Barbara Putz, Ulrich Gerbracht, and Rolf Schulte-Hermann
Cancer Res 1990 50: 3701-3708. [Abstract] [PDF]  

Human Cervical and Foreskin Epithelial Cells Immortalized by Human Papillomavirus DNAs Exhibit Dysplastic Differentiation in Vivo

C. D. Woodworth, S. Waggoner, W. Barnes, M. H. Stoler, and J. A. DiPaolo
Cancer Res 1990 50: 3709-3715. [Abstract] [PDF]  

Regression of Nitrosamine-induced Pancreatic Cancers in Hamsters Treated with Luteinizing Hormone-releasing Hormone Antagonists or Agonists

Bela Szende, Gordan Srkalovic, Kate Groot, Karoly Lapis, and Andrew V. Schally
Cancer Res 1990 50: 3716-3721. [Abstract] [PDF]  

Multistage Neoplastic Transformation of Syrian Hamster Embryo Cells Cultured at pH 6.70

R. A. LeBoeuf, G. A. Kerckaert, M. J. Aardema, and D. P. Gibson
Cancer Res 1990 50: 3722-3729. [Abstract] [PDF]  

Growth-regulating Functions of Human Papillomavirus Early Gene Products in Cervical Cancer Cells Acting Dominant over Enhanced Epidermal Growth Factor Receptor Expression

Magnus von Knebel Doeberitz, Lutz Gissmann, and Harald zur Hausen
Cancer Res 1990 50: 3730-3736. [Abstract] [PDF]  

Role of 1q Trisomy in Tumorigenicity, Growth, and Metastasis of Human Leukemic B-Cell Clones in Nude Mice

Tarunendu Ghose, Christine L. Y. Lee, Louis A. Fernandez, Spencer H. S. Lee, Raja Raman, and Patricia Colp
Cancer Res 1990 50: 3737-3742. [Abstract] [PDF]  

Melanocytotoxicity and Antimelanoma Effects of Phenolic Amine Compounds in Mice in Vivo

Frank Alena, Kowichi Jimbow, and Shosuke Ito
Cancer Res 1990 50: 3743-3747. [Abstract] [PDF]  

Programmed Cell Death during Regression of PC-82 Human Prostate Cancer following Androgen Ablation

Natasha Kyprianou, Hugh F. English, and John T. Isaacs
Cancer Res 1990 50: 3748-3753. [Abstract] [PDF]  

A Congenic Line of the BALB/c Mouse Strain with the Endogenous Mouse Mammary Tumor Virus Proviral Gene Mtv-3: Tissue-specific Expression and Correlation with Resistance to Mouse Mammary Tumor Virus Infection and Tumorigenesis

Pierre Hainaut, Marc Castellazzi, Dominique Gonzales, Nathalie Clausse, Jo Hilgers, and Michel Crépin
Cancer Res 1990 50: 3754-3760. [Abstract] [PDF]  

Inhibition of p34^cdc2 Kinase Activity by Etoposide or Irradiation as a Mechanism of G₂ Arrest in Chinese Hamster Ovary Cells

Richard B. Lock and Warren E. Ross
Cancer Res 1990 50: 3761-3766. [Abstract] [PDF]  

Possible Role for p34^cdc2 Kinase in Etoposide-induced Cell Death of Chinese Hamster Ovary Cells

Richard B. Lock and Warren E. Ross
Cancer Res 1990 50: 3767-3771. [Abstract] [PDF]  

Dose-Response Relationship between O⁶-Methylguanine Formation in Clara Cells and Induction of Pulmonary Neoplasia in the Rat by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone

Steven A. Belinsky, Julie F. Foley, Catherine M. White, Marshall W. Anderson, and Robert R. Maronpot
Cancer Res 1990 50: 3772-3780. [Abstract] [PDF]  

A Heparan Sulfate-containing Fraction of Bone Marrow Stroma Induces Maturation of HL-60 Cells in Vitro

Sharon D. Luikart, Charles A. Maniglia, Leo T. Furcht, James B. McCarthy, and Theodore R. Oegema, Jr.
Cancer Res 1990 50: 3781-3785. [Abstract] [PDF]  

Estradiol Stimulation and Inhibition of Cell Growth in New Estrogen-sensitive Cell Lines and Tumors Established from the MtTF₄ Tumor

Marie-Odile Joly-Pharaboz, Fei Zhou-Li, Bruno Bouillard, and Jean Andre
Cancer Res 1990 50: 3786-3794. [Abstract] [PDF]  

Frequency and Pattern of Karyotypic Abnormalities in Human Prostate Cancer

Arthur R. Brothman, Donna M. Peehl, Ankita M. Patel, and John E. McNeal
Cancer Res 1990 50: 3795-3803. [Abstract] [PDF]  

Clinical and Epidemiological Investigation:

Automated Quantitation of Immunocytochemically Localized Estrogen Receptors in Human Breast Cancer

Richard A. McClelland, Pauline Finlay, Kerry J. Walker, Denise Nicholson, John F. R. Robertson, Roger W. Blamey, and Robert I. Nicholson
Cancer Res 1990 50: 3545-3550. [Abstract] [PDF]  

Characterization of Glutathione S-Transferase Expression in Lymphocytes from Chronic Lymphocytic Leukemia Patients

John C. Schisselbauer, Robert Silber, Esperanza Papadopoulos, Kevin Abrams, Frank P. LaCreta, and Kenneth D. Tew
Cancer Res 1990 50: 3562-3568. [Abstract] [PDF]  

Epidemiology of Hairy Cell Leukemia in Los Angeles County

Leslie Bernstein, Patricia Newton, and Ronald K. Ross
Cancer Res 1990 50: 3605-3609. [Abstract] [PDF]  

Physical Activity and Risk of Large Bowel Cancer in the Framingham Study

Rachel Ballard-Barbash, Arthur Schatzkin, Demetrius Albanes, Mark H. Schiffman, Bernard E. Kreger, William B. Kannel, Keaven M. Anderson, and William E. Helsel
Cancer Res 1990 50: 3610-3613. [Abstract] [PDF]  

Risk Factors for in Situ Cervical Cancer: Results from a Case-Control Study

Carol J. Jones, Louise A. Brinton, Richard F. Hamman, Paul D. Stolley, Herman F. Lehman, Robert S. Levine, and Katherine Mallin
Cancer Res 1990 50: 3657-3662. [Abstract] [PDF]  

Letter to the Editor:

Stomach Cancer and Cigarette Smoking among U. S. Veterans, 1954–1980

Joseph K. McLaughlin, Zdenek Hrubec, William J. Blot, and Joseph F. Fraumeni, Jr.
Cancer Res 1990 50: 3804 [PDF]  

Meeting Report:

Workshop Report from the Division of Research Grants, National Institutes of Health: Molecular Genetic Approaches to the Analysis of Malignant Transformation—A Pathology B Study Section Workshop

Philip Furmanski, Frank Chisari, Angel Pellicer, Nelson Fausto, and Martin Padarathsingh
Cancer Res 1990 50: 3805-3806. [PDF]  

Erratum:

Detection and Partial Characterization of Receptors for [D-Trp⁶]-Luteinizing Hormone-releasing Hormone and Epidermal Growth Factor in Human Endometrial Carcinoma

Cancer Res 1990 50: 3808 [PDF]  

Amplification of the c-myc Gene in Human Medulloblastoma Cell Lines and Xenografts

Cancer Res 1990 50: 3809 [PDF]  

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