Perspectives in Cancer Research:

Mammalian O⁶-Alkylguanine-DNA Alkyltransferase: Regulation and Importance in Response to Alkylating Carcinogenic and Therapeutic Agents

Anthony E. Pegg
Cancer Res 1990 50: 6119-6129. [PDF]  

Special Lecture:

Critical Factors in the Biology of Human Cancer Metastasis: Twenty-eighth G. H. A. Clowes Memorial Award Lecture

Isaiah J. Fidler
Cancer Res 1990 50: 6130-6138. [Abstract] [PDF]  

Articles:

K-ras Activation in Neoplasms of the Human Female Reproductive Tract

Takayuki Enomoto, Masaki Inoue, Alan O. Perantoni, Naoki Terakawa, Osamu Tanizawa, and Jerry M. Rice
Cancer Res 1990 50: 6139-6145. [Abstract] [PDF]  

Two Chromosomal Locations for Human Ornithine Decarboxylase Gene Sequences and Elevated Expression in Colorectal Neoplasia

Diane M. Radford, Hiroshi Nakai, Roger L. Eddy, Linda L. Haley, Mary G. Byers, W. Michael Henry, David D. Lawrence, Carl W. Porter, and Thomas B. Shows
Cancer Res 1990 50: 6146-6153. [Abstract] [PDF]  

Topoisomerase II-mediated DNA Damage of Episomes in Tumor-bearing Mice

Emily B. Cullinan, Loretta S. Gawron, Youcef M. Rustum, and Terry A. Beerman
Cancer Res 1990 50: 6154-6157. [Abstract] [PDF]  

Selective Immunosuppressive Action of a Factor Produced by Colon Cancer Cells

Ellen C. Ebert, Arthur I. Roberts, Dennis Devereux, and Hideaki Nagase
Cancer Res 1990 50: 6158-6161. [Abstract] [PDF]  

Tumor Promoter-stimulated M_r 92,000 Gelatinase Secreted by Normal and Malignant Human Cells: Isolation and Characterization of the Enzyme from HT1080 Tumor Cells

Ute M. Moll, Gary L. Youngleib, Karen B. Rosinski, and James P. Quigley
Cancer Res 1990 50: 6162-6170. [Abstract] [PDF]  

Rearrangements in the Human T-Cell-Receptor -Chain Locus in Patients with Adult T-Cell Leukemia Carrying Translocations Involving Chromosome 14q11

Masaharu Isobe, Naoki Sadamori, Giadomenico Russo, Shoichi Shimizu, Shunji Yamamori, Takahiro Itoyama, Yasuaki Yamada, Shuichi Ikeda, Michito Ichimaru, Jacob Kagan, and Carlo M. Croce
Cancer Res 1990 50: 6171-6175. [Abstract] [PDF]  

Comparison of DNA Aneuploidy of Primary and Metastatic Spontaneous Canine Osteosarcomas

Michael H. Fox, Leslie W. Armstrong, Steven J. Withrow, Barbara E. Powers, Susan M. LaRue, Rodney C. Straw, and Edward L. Gillette
Cancer Res 1990 50: 6176-6178. [Abstract] [PDF]  

Roles of Transforming Growth Factor ß in Inhibition of Androgen-induced Growth of Shionogi Carcinoma Cells in Serum-free Medium

Hiroshi Yamanishi, Norio Nonomura, Akira Tanaka, Toshiyuki Yasui, Yasuko Nishizawa, Keishi Matsumoto, and Bunzo Sato
Cancer Res 1990 50: 6179-6183. [Abstract] [PDF]  

Independent Expression and Cellular Processing of M_r 72,000 Type IV Collagenase and Interstitial Collagenase in Human Tumorigenic Cell Lines

Peter D. Brown, Anna T. Levy, Inger M. K. Margulies, Lance A. Liotta, and William G. Stetler-Stevenson
Cancer Res 1990 50: 6184-6191. [Abstract] [PDF]  

Induction of Covalent DNA Modifications and Micronucleated Erythrocytes by 4-Nitroquinoline 1-Oxide in Adult and Fetal Mice

Lee-Jane W. Lu, Jennifer R. Baxter, Mian-Ying Wang, Barbara L. Harper, Fumiyo Tasaka, and Kohfuku Kohda
Cancer Res 1990 50: 6192-6198. [Abstract] [PDF]  

Effect of Heat Treatment on Tumor Cells and Antitumor Effector Cells

Keiichi Mise, Norimichi Kan, Takashi Okino, Masaki Nakanishi, Kohei Satoh, Yasufumi Teramura, Seiji Yamasaki, Kazuhisa Ohgaki, and Takayoshi Tobe
Cancer Res 1990 50: 6199-6202. [Abstract] [PDF]  

Dose-dependent Neurotoxicity of High-Dose Busulfan in Children: A Clinical and Pharmacological Study

Gilles Vassal, Alain Deroussent, Olivier Hartmann, Dominique Challine, Ellen Benhamou, Dominique Valteau-Couanet, Laurence Brugières, Chantal Kalifa, Alain Gouyette, and Jean Lemerle
Cancer Res 1990 50: 6203-6207. [Abstract] [PDF]  

T47D_CO Cells, Genetically Unstable and Containing Estrogen Receptor Mutations, Are a Model for the Progression of Breast Cancers to Hormone Resistance

Mark L. Graham, II, Nancy L. Krett, Louise A. Miller, Kimberly K. Leslie, David F. Gordon, William M. Wood, Lisa L. Wei, and Kathryn B. Horwitz
Cancer Res 1990 50: 6208-6217. [Abstract] [PDF]  

Mechanism of Diethyldithiocarbamate Modulation of Murine Bone Marrow Toxicity

Therese K. Schmalbach and Richard F. Borch
Cancer Res 1990 50: 6218-6221. [Abstract] [PDF]  

Expression of Rat Microsomal Epoxide Hydrolase Gene during Liver Chemical Carcinogenesis

Shinichi Kondo, Brian I. Carr, Kenkichi Takagi, Ting H. Huang, Yun-Mei Chou, Kazushige Yokoyama, and Keiichi Itakura
Cancer Res 1990 50: 6222-6228. [Abstract] [PDF]  

An Enzyme-linked Immunosorbent Assay for Cancer Procoagulant and Its Potential as a New Tumor Marker

Stuart G. Gordon and Barbara A. Cross
Cancer Res 1990 50: 6229-6234. [Abstract] [PDF]  

Role of the AKR Gene Locus AKv-1 in Susceptibility to Chemical Induction of Thymic Lymphomas

Frederick F. Becker
Cancer Res 1990 50: 6235-6237. [Abstract] [PDF]  

Desensitization and Resensitization of Rat Pituitary Tumor Cells in Long-Term Culture to the Effects of the Somatostatin Analogue SMS 201–995 on Cell Growth and Prolactin Secretion

Jan W. Koper, Leo J. Hofland, Peter M. van Koetsveld, Fred den Holder, and Steven W. J. Lamberts
Cancer Res 1990 50: 6238-6242. [Abstract] [PDF]  

Modulation of the Immune Response to Transplanted Tumors in Rats by Selective Depletion of Neutrophils in Vivo Using a Monoclonal Antibody: Abrogation of Specific Transplantation Resistance to Chemical Carcinogen-induced Syngeneic Tumors by Selective Depletion of Neutrophils in Vivo

Yasuhiko Midorikawa, Takao Yamashita, and Fujiro Sendo
Cancer Res 1990 50: 6243-6247. [Abstract] [PDF]  

Regulation of Carcinoembryonic Antigen Expression in Different Human Colorectal Tumor Cells by Interferon-

Fiorella Guadagni, Patricia L. Witt, Paul F. Robbins, Jeffrey Schlom, and John W. Greiner
Cancer Res 1990 50: 6248-6255. [Abstract] [PDF]  

Requirements for the Generation of a Lyt-2⁺ T-Cell Proliferative Response to a Syngeneic Tumor in the Absence of L3T4⁺ T-Cells

Donald E. Kern, Jay P. Klarnet, Martin A. Cheever, and Philip D. Greenberg
Cancer Res 1990 50: 6256-6263. [Abstract] [PDF]  

In Vitro Assessment of the Effects of Granulocyte-Macrophage Colony-stimulating Factor on Primary Human Tumors and Derived Lines

Richard S. Foulke, Martha H. Marshall, Paul P. Trotta, and Daniel D. Von Hoff
Cancer Res 1990 50: 6264-6267. [Abstract] [PDF]  

Combinations of Retinoic Acid with Either Sodium Butyrate, Dimethyl Sulfoxide, or Hexamethylene Bisacetamide Synergistically Induce Differentiation of the Human Myeloid Leukemia Cell Line HL60

Theodore R. Breitman and Ruyi He
Cancer Res 1990 50: 6268-6273. [Abstract] [PDF]  

Medical History and Primary Liver Cancer

Carlo La Vecchia, Eva Negri, Barbara D'Avanzo, Peter Boyle, and Silvia Franceschi
Cancer Res 1990 50: 6274-6277. [Abstract] [PDF]  

Cathepsin B to Cysteine Proteinase Inhibitor Balance in Metastatic Cell Subpopulations Isolated from Murine Tumors

Jurij Rozhin, Angel P. Gomez, Grace H. Ziegler, Kevin K. Nelson, Young Sook Chang, Dunne Fong, James M. Onoda, Kenneth V. Honn, and Bonnie F. Sloane
Cancer Res 1990 50: 6278-6284. [Abstract] [PDF]  

Evidence That High Mannose Glycopeptides Are Able to Functionally Interact with Recombinant Tumor Necrosis Factor and Recombinant Interleukin 1

Andrew Muchmore, Jean Decker, Alan Shaw, and Paul Wingfield
Cancer Res 1990 50: 6285-6290. [Abstract] [PDF]  

Expression of Human -Actinin in Human Hepatocellular Carcinoma

Masaki Nishiyama, Mehmet Ozturk, Mark Frohlich, Ken-ichi Mafune, Glenn Steele,, Jr., and Jack R. Wands
Cancer Res 1990 50: 6291-6294. [Abstract] [PDF]  

Combinations of Anti-Transferrin Receptor Monoclonal Antibodies Inhibit Human Tumor Cell Growth in Vitro and in Vivo: Evidence for Synergistic Antiproliferative Effects

Suhaila White, Raymond Taetle, Paul A. Seligman, Mary Rutherford, and Ian S. Trowbridge
Cancer Res 1990 50: 6295-6301. [Abstract] [PDF]  

Phase I Trial of Intraperitoneal Recombinant Interleukin-2/Lymphokine-activated Killer Cells in Patients with Ovarian Cancer

James A. Stewart, Jerome L. Belinson, Ann L. Moore, John A. Dorighi, Barbara W. Grant, Larry D. Haugh, John D. Roberts, Richard J. Albertini, and Richard F. Branda
Cancer Res 1990 50: 6302-6310. [Abstract] [PDF]  

Increased Lysis of Melanoma by in Vivo-elicited Human Lymphokine-activated Killer Cells after Addition of Antiganglioside Antibodies in Vitro

William Harel, Hungyi Shau, Carl G. Hadley, Alton C. Morgan, Jr., Ralph A. Reisfeld, David A. Cheresh, and Malcolm S. Mitchell
Cancer Res 1990 50: 6311-6315. [Abstract] [PDF]  

Antisense Inhibition of Single Copy N-myc Expression Results in Decreased Cell Growth without Reduction of c-myc Protein in a Neuroepithelioma Cell Line

Angelo Rosolen, Luke Whitesell, Naohiko Ikegaki, Roger H. Kennett, and Leonard M. Neckers
Cancer Res 1990 50: 6316-6322. [Abstract] [PDF]  

Megakaryocytic Differentiation of K562 Cells Is Associated with Changes in the Cytoskeletal Organization and the Pattern of Chromatographically Distinct Forms of Phosphotyrosyl-specific Protein Phosphatases

T. Martin Bütler, Andrew Ziemiecki, and Robert R. Friis
Cancer Res 1990 50: 6323-6329. [Abstract] [PDF]  

Genetic Origin of a Trophoblastic Choriocarcinoma

R. S. K. Chaganti, Prasad R. K. Koduru, Ranajit Chakraborty, and Walter B. Jones
Cancer Res 1990 50: 6330-6333. [Abstract] [PDF]  

Growth Adaptation to Methotrexate of HT-29 Human Colon Carcinoma Cells Is Associated with Their Ability to Differentiate into Columnar Absorptive and Mucus-secreting Cells

Thécla Lesuffleur, Alain Barbat, Elisabeth Dussaulx, and Alain Zweibaum
Cancer Res 1990 50: 6334-6343. [Abstract] [PDF]  

In Situ Distribution of the ß-Subunit of Platelet-derived Growth Factor Receptor in Nonneoplastic Tissue and in Soft Tissue Tumors

Wilbur A. Franklin, William H. Christison, Margo Colley, Anthony G. Montag, Janet K. Stephens, and Charles E. Hart
Cancer Res 1990 50: 6344-6348. [Abstract] [PDF]  

Genetic Instability and the Acquisition of Metastatic Ability by Rat Mammary Cancer Cells following v-H-ras Oncogene Transfection

Tomohiko Ichikawa, Natasha Kyprianou, and John T. Isaacs
Cancer Res 1990 50: 6349-6357. [Abstract] [PDF]  

Tumor-associated Antigens Common to Humans and Chemically Induced Colonic Tumors of the Rat

Jayant D. Shetye, Carlos A. Rubio, Ulrika Harmenberg, James Ware, Annika Duvander, and Håkan T. Mellstedt
Cancer Res 1990 50: 6358-6363. [Abstract] [PDF]  

Differential Spectrum of Expression of Neural Cell Adhesion Molecule Isoforms and L1 Adhesion Molecules on Human Neuroectodermal Tumors

Dominique F. Figarella-Branger, Pascale L. Durbec, and Geneviève N. Rougon
Cancer Res 1990 50: 6364-6370. [Abstract] [PDF]  

Effect of Liposome Composition and Other Factors on the Targeting of Liposomes to Experimental Tumors: Biodistribution and Imaging Studies

Alberto Gabizon, David C. Price, John Huberty, Robert S. Bresalier, and Demetrios Papahadjopoulos
Cancer Res 1990 50: 6371-6378. [Abstract] [PDF]  

Enhanced Therapeutic Efficacy against an Ovarian Tumor Xenograft of Immunotoxins Used in Conjunction with Recombinant -Interferon

J. W. Pearson, E. Hedrick, W. E. Fogler, R. L. Bull, D. K. Ferris, C. W. Riggs, R. H. Wiltrout, G. Sivam, A. C. Morgan, E. Groves, and D. L. Longo
Cancer Res 1990 50: 6379-6388. [Abstract] [PDF]  

Antiproliferative and Cytotoxic Effects of Single and Combined Treatment with Tumor Necrosis Factor and/or Interferon on a Human Renal Cell Carcinoma Xenotransplanted into nu/nu Mice: Cell Kinetic Studies

Heinz Baisch, Ullrich Otto, and Günter Klöppel
Cancer Res 1990 50: 6389-6395. [Abstract] [PDF]  

Induction of Cells with Phenotypic Features of Neuronal Cells by Treatment with Dibutyryl Cyclic Adenosine 3',5'-Monophosphate in a Human Parotid Gland Adenocarcinoma Cell Line in Culture

Shinichi Nagamine, Tetsuo Yanagawa, Takashi Bando, Yoshiaki Yura, Hideo Yoshida, and Mitsunobu Sato
Cancer Res 1990 50: 6396-6404. [Abstract] [PDF]  

Murine Monoclonal Antibodies to Colon-specific Antigen p

David V. Gold, Mary Ann Nocera, Richard Stephens, and David M. Goldenberg
Cancer Res 1990 50: 6405-6409. [Abstract] [PDF]  

11p13-15 Is a Specific Region of Chromosomal Rearrangement in Gastric and Esophageal Adenocarcinomas

Eduardo Rodriguez, Pulivarthi H. Rao, Marc Ladanyi, Nasser Altorki, Anthony P. Albino, David P. Kelsen, Suresh C. Jhanwar, and R. S. K. Chaganti
Cancer Res 1990 50: 6410-6416. [Abstract] [PDF]  

Gene Amplification in Gastric and Esophageal Adenocarcinomas

Jane Houldsworth, Carlos Cordon-Cardo, Marc Ladanyi, David P. Kelsen, and R. S. K. Chaganti
Cancer Res 1990 50: 6417-6422. [Abstract] [PDF]  

Immunohistochemical and Pharmacokinetic Characterization of the Site-specific Immunoconjugate CYT-356 Derived from Antiprostate Monoclonal Antibody 7E11-C5

A. Dwight Lopes, Wendy L. Davis, Maurice J. Rosenstraus, Albert J. Uveges, and Steven C. Gilman
Cancer Res 1990 50: 6423-6429. [Abstract] [PDF]  

Announcements

Cancer Res 1990 50: 6436-6438. [PDF]  

Meeting Report:

Steroid Receptors, Transcription Factors, and Gene Expression: AACR Special Conference in Cancer Research

Larry Denner, Hongjun Ji, Larry Denner, Russell D. Owen, Larry Denner, Gregory J. Kato, Larry Denner, Christine L. Clarke, Larry Denner, Hae-Young Lee, Larry Denner, Paul M. Richardson, Larry Denner, Uttam K. Pati, and Larry Denner
Cancer Res 1990 50: 6430-6435. [PDF]  

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