Perspectives in Cancer Research:

Increased Cell Division as a Cause of Human Cancer

Susan Preston-Martin, Malcolm C. Pike, Ronald K. Ross, Peter A. Jones, and Brian E. Henderson
Cancer Res 1990 50: 7415-7421. [Abstract] [PDF]  

Articles:

Effect of Recombinant Human Leukocyte, Fibroblast, and Immune Interferons on Expression of Class I and II Major Histocompatibility Complex and Invariant Chain in Early Passage Human Melanoma Cells

Paola Nisticò, Raffaele Tecce, Patrizio Giacomini, Andrea Cavallari, Igea D'Agnano, Paul B. Fisher, and Pier Giorgio Natali
Cancer Res 1990 50: 7422-7429. [Abstract] [PDF]  

Combination of Nicotinamide and Hyperthermia to Eliminate Radioresistant Chronically and Acutely Hypoxic Tumor Cells

Michael R. Horsman, David J. Chaplin, and Jens Overgaard
Cancer Res 1990 50: 7430-7436. [Abstract] [PDF]  

Regulation of the Cell Surface Expression of a Nonspecific Cross-Reacting Antigen Variant during Differentiation of HL-60 Cells

Ilse Novak-Hofer, Peter Bläuenstein, and P. August Schubiger
Cancer Res 1990 50: 7437-7443. [Abstract] [PDF]  

Glycosphingolipids of Human Gliomas

Richard Jennemann, Appletree Rodden, Bernhard L. Bauer, Hans-Dieter Mennel, and Herbert Wiegandt
Cancer Res 1990 50: 7444-7449. [Abstract] [PDF]  

Adoptive Transfer of Tumor Cytotoxic Macrophages Generated in Vitro from Circulating Blood Monocytes: A New Approach to Cancer Immunotherapy

Reinhard Andreesen, Carmen Scheibenbogen, Wolfram Brugger, Stefan Krause, Hans-Gerd Meerpohl, Hans-Georg Leser, Hans Engler, and Georg W. Löhr
Cancer Res 1990 50: 7450-7456. [Abstract] [PDF]  

Production of Interleukin 6 from Human Liver Cell Lines: Production of Interleukin 6 Is Not Concurrent with the Production of -Fetoprotein

Tetsuya Matsuguchi, Seiichi Okamura, Chiyuki Kawasaki, and Yoshiyuki Niho
Cancer Res 1990 50: 7457-7459. [Abstract] [PDF]  

Expression of Growth-related Genes during Tumor Progression in v-raf-transformed Rat Liver Epithelial Cells

Lori L. Hampton, Peter J. Worland, Betty Yu, Snorri S. Thorgeirsson, and Anthony C. Huggett
Cancer Res 1990 50: 7460-7467. [Abstract] [PDF]  

Altered Responsiveness of Rat Liver Epithelial Cells to Transforming Growth Factor ß₁ following Their Transformation with v-raf

Anthony C. Huggett, Lori L. Hampton, Caroline P. Ford, Peter J. Wirth, and Snorri S. Thorgeirsson
Cancer Res 1990 50: 7468-7475. [Abstract] [PDF]  

Prolonged Serum Half-Life of Antineoplastic Drugs by Incorporation into the Low Density Lipoprotein

P. Chris de Smidt and Theo J. C. van Berkel
Cancer Res 1990 50: 7476-7482. [Abstract] [PDF]  

Metabolism of Mitomycin C by DT-Diaphorase: Role in Mitomycin C-induced DNA Damage and Cytotoxicity in Human Colon Carcinoma Cells

David Siegel, Neil W. Gibson, Peter C. Preusch, and David Ross
Cancer Res 1990 50: 7483-7489. [Abstract] [PDF]  

Phase I Evaluation of a Combination of Monoclonal Antibody R24 and Interleukin 2 in Patients with Metastatic Melanoma

Dean F. Bajorin, Paul B. Chapman, George Wong, Daniel G. Coit, Jolanta Kunicka, Joseph Dimaggio, Carlos Cordon-Cardo, Carlos Urmacher, Lucy Dantes, Mary Agnes Templeton, John Liu, Herbert F. Oettgen, and Alan N. Houghton
Cancer Res 1990 50: 7490-7495. [Abstract] [PDF]  

Phase I and Clinical Pharmacology Trial of 502U83 Using a Monthly Single Dose Schedule

Daniel D. Von Hoff, John G. Kuhn, Kathleen A. Havlin, Anne-Marie Langevin, Thomas D. Brown, Geoffrey R. Weiss, Judy N. Turner, Joseph Purvis, V. Sol Lucas, Kenneth W. Bair, William Wargin, James Hubbell, Richard L. Tuttle, Jim M. Koeller, and Gregory L. Freeman
Cancer Res 1990 50: 7496-7500. [Abstract] [PDF]  

A Case-Cohort Study of Diet and Stomach Cancer

Po-Huang Chyou, Abraham M. Y. Nomura, Jean H. Hankin, and Grant N. Stemmermann
Cancer Res 1990 50: 7501-7504. [Abstract] [PDF]  

Role of Endocytosis in the Action of Ether Lipids on WEHI-3B, HL60, and FDCP-Mix A4 Cells

G. W. Bazill and T. M. Dexter
Cancer Res 1990 50: 7505-7512. [Abstract] [PDF]  

Inherent Sensitivity and Induced Resistance to Chemotherapeutic Drugs and Irradiation in Human Cancer Cell Lines: Relationship to Mutation Frequencies

Christopher N. Parris, M. Claire Walker, John R. W. Masters, and Colin F. Arlett
Cancer Res 1990 50: 7513-7518. [Abstract] [PDF]  

Pharmacokinetics in the Rat of a Panel of Immunotoxins Made with Abrin A Chain, Ricin A Chain, Gelonin, and Momordin

Edward J. Wawrzynczak, Alan J. Cumber, Raymond V. Henry, Julie May, David R. Newell, Geoffrey D. Parnell, Nan R. Worrell, and J. Anthony Forrester
Cancer Res 1990 50: 7519-7526. [Abstract] [PDF]  

Melphalan-induced Mutagenesis in an SV40-based Shuttle Vector: Predominance of A · TT · A Transversions

Peng Wang, Richard A. O. Bennett, and Lawrence F. Povirk
Cancer Res 1990 50: 7527-7531. [Abstract] [PDF]  

In Vitro Modulation and Relationship between N-myc and HLA Class I RNA Steady-State Levels in Human Neuroblastoma Cells

Nicole Gross, Daniel Beck, and Simone Favre
Cancer Res 1990 50: 7532-7536. [Abstract] [PDF]  

Modulation of Drug Sensitivity by Dipyridamole in Multidrug Resistant Tumor Cells in Vitro

David R. Shalinsky, Michael Andreeff, and Stephen B. Howell
Cancer Res 1990 50: 7537-7543. [Abstract] [PDF]  

Multiple Membrane Transport Systems for the Uptake of Folate-based Thymidylate Synthase Inhibitors

Gerrit Jansen, Jan H. Schornagel, G. Robbin Westerhof, Gert Rijksen, David R. Newell, and Ann L. Jackman
Cancer Res 1990 50: 7544-7548. [Abstract] [PDF]  

Appendectomy, Appendicitis, and Large Bowel Cancer

Gary D. Friedman and Bruce H. Fireman
Cancer Res 1990 50: 7549-7551. [Abstract] [PDF]  

Characterization of the Elastase 1-Simian Virus 40 T-Antigen Mouse Model of Pancreatic Carcinoma: Effects of Sex and Diet

Daniel S. Longnecker, Elna T. Kuhlmann, and Daniel H. Freeman, Jr.
Cancer Res 1990 50: 7552-7554. [Abstract] [PDF]  

Mechanisms of Toxicity of Hepsulfam in Human Tumor Cell Lines

Diane Y. Pacheco, Cheryl Cook, Jeffrey R. Hincks, and Neil W. Gibson
Cancer Res 1990 50: 7555-7558. [Abstract] [PDF]  

In Vitro Studies on the Mechanism of Action of Hepsulfam in Chronic Myelogenous Leukemia Patients

Jeffrey R. Hincks, Arun Adlakha, Cheryl A. Cook, Candace S. Johnson, Philip Furmanski, and Neil W. Gibson
Cancer Res 1990 50: 7559-7563. [Abstract] [PDF]  

Carcinogenic Sulfide Salts of Nickel and Cadmium Induce H₂O₂ Formation by Human Polymorphonuclear Leukocytes

Zhaojing Zhong, Walter Troll, Karen L. Koenig, and Krystyna Frenkel
Cancer Res 1990 50: 7564-7570. [Abstract] [PDF]  

Nuclear DNA Content of Altered Hepatic Foci in a Rat Liver Carcinogenesis Model

Jian H. Wang, Lucila I. Hinrichsen, Cecilia M. Whitacre, Ronald L. Cechner, and Oscar Sudilovsky
Cancer Res 1990 50: 7571-7576. [Abstract] [PDF]  

Persistent Reduction of Indigenous DNA Modification (I-Compound) Levels in Liver DNA from Male Fischer Rats Fed Choline-devoid Diet and in DNA of Resulting Neoplasms

Donghui Li, Decheng Xu, Nalini Chandar, Benito Lombardi, and Kurt Randerath
Cancer Res 1990 50: 7577-7580. [Abstract] [PDF]  

Inhibitory Effects of Transforming Growth Factor ß₁ on Mitogenic Response, Transforming Growth Factor , and c-myc in Quiescent, Well-Differentiated Colon Carcinoma Cells

Kathleen M. Mulder, Qing Zhong, Ho Gene Choi, Lisa E. Humphrey, and Michael G. Brattain
Cancer Res 1990 50: 7581-7586. [Abstract] [PDF]  

Effects of N⁴-Behenoyl-1-ß-D-Arabinofuranosylcytosine on Blast Progenitors of Acute Myeloblastic Leukemia

Nobuo Nara, Shuji Tohda, Toshiya Suzuki, Kaoru Nagata, Yoko Yamashita, Yasufumi Imai, Yasuo Maruyama, and Junji Tomiyama
Cancer Res 1990 50: 7587-7592. [Abstract] [PDF]  

Gene Expression in Clonally Derived Cell Lines Produced by in Vitro Transformation of Rat Fetal Hepatocytes: Isolation of Cell Lines Which Retain Liver-specific Markers

G. C. T. Yeoh, C. Hilliard, S. Fletcher, and A. Douglas
Cancer Res 1990 50: 7593-7602. [Abstract] [PDF]  

Differentiation-dependent Expression of I and Sialyl I Antigens in the Developing Lung of Human Embryos and in Lung Cancers

Shigeyuki Itai, Junko Nishikata, Naofumi Takahashi, Osamu Tanaka, Yoshito Matsubara, Shizuo Hasegawa, Noboru Yanai, Kazuo Takaoka, Shigeki Arii, Takayoshi Tobe, and Reiji Kannagi
Cancer Res 1990 50: 7603-7611. [Abstract] [PDF]  

Definition of a Sequence, RYVVLPR, within Laminin Peptide F-9 that Mediates Metastatic Fibrosarcoma Cell Adhesion and Spreading

Amy P. N. Skubitz, James B. McCarthy, Qi Zhao, Xiang-yan Yi, and Leo T. Furcht
Cancer Res 1990 50: 7612-7622. [Abstract] [PDF]  

Relationship between Secreted Urokinase Plasminogen Activator Activity and Metastatic Potential in Murine B16 Cells Transfected with Human Urokinase Sense and Antisense Genes

Heron Yu and Richard M. Schultz
Cancer Res 1990 50: 7623-7633. [Abstract] [PDF]  

In Vivo Selection of Human Tumor Cells Resistant to Monoclonal Antibody-Vinca Alkaloid Immunoconjugates

James J. Starling, Ronald S. Maciak, N. Ann Hinson, Joann Hoskins, Bennett C. Laguzza, Robert A. Gadski, Joann Strnad, Lana Rittmann-Grauer, Sonia V. DeHerdt, Thomas F. Bumol, and Robert E. Moore
Cancer Res 1990 50: 7634-7640. [Abstract] [PDF]  

Importance of Tumor-specific Cytotoxic CD8⁺ T-Cells in Eradication of a Large Subcutaneous MOPC-315 Tumor following Low-Dose Melphalan Therapy

Blaine Y. Takesue, Joseph M. Pyle, and Margalit B. Mokyr
Cancer Res 1990 50: 7641-7649. [Abstract] [PDF]  

Effect of Epidermal Growth Factor on the Cellular Proliferation and Phenotype of a Neoplastic Human Salivary Intercalated Duct Cell Line or Its Derivatives

Walid Aladib, Hideo Yoshida, and Mitsunobu Sato
Cancer Res 1990 50: 7650-7661. [Abstract] [PDF]  

Effects of Sex Difference, Gonadectomy, and Estrogen on N-Methyl-N-nitrosourea Induced Rat Thyroid Tumors

Masahiro Mori, Masashi Naito, Hiromitsu Watanabe, Nobuo Takeichi, Kiyohiko Dohi, and Akihiro Ito
Cancer Res 1990 50: 7662-7667. [Abstract] [PDF]  

Expression of Epithelial Antigens Exo-1 and EPM-1 in Human Epidermal Keratinocyte Maturation and Benign and Malignant Neoplasia

Reinhard Klingel, Petra Boukamp, Roland Moll, Wolfgang Tilgen, Norbert E. Fusenig, Karl-Hermann Meyer zum Büschenfelde, and Wolfgang G. Dippold
Cancer Res 1990 50: 7668-7676. [Abstract] [PDF]  

Uterine Adenocarcinoma in Mice following Developmental Treatment with Estrogens: A Model for Hormonal Carcinogenesis

Retha R. Newbold, Bill C. Bullock, and John A. McLachlan
Cancer Res 1990 50: 7677-7681. [Abstract] [PDF]  

A Ki-1 (CD30)-positive T (E+, CD4+, Ia+)-Cell Line, DL-40, Established from Aggressive Large Cell Lymphoma

Ichiro Kubonishi, Hiroshi Sonobe, Tatsushi Miyagi, Yoshihito Iwahara, Junko H. Ohyashiki, Kazuma Ohyashiki, Keisuke Toyama, Yuji Ohtsuki, and Isao Miyoshi
Cancer Res 1990 50: 7682-7685. [Abstract] [PDF]  

An in Vivo Study of the Role of the Tumor Cell Cytoskeleton in Tumor Cell-Platelet-Endothelial Cell Interactions

Hemi Chopra, Suzanne E. G. Fligiel, James S. Hatfield, Kevin K. Nelson, Clement A. Diglio, John D. Taylor, and Kenneth V. Honn
Cancer Res 1990 50: 7686-7696. [Abstract] [PDF]  

Enhanced Expression of Ganglioside G_D3 in Human and Rat Hepatocellular Carcinoma Cells and NIH 3T3 Cells Transfected with Human Tumor DNAs

Jian Nan Ye, Tian-gue Gu, Liang Xia, Martin J. Murphy, Jr., Way Lee, Neng-hau Gao, Jian-ren Gu, and J. Peter Fuhrer
Cancer Res 1990 50: 7697-7702. [Abstract] [PDF]  

A Novel Human Myeloid Leukemia Cell Line, NKM-1, Coexpressing Granulocyte Colony-stimulating Factor Receptors and Macrophage Colony-stimulating Factor Receptors

Takae Kataoka, Yoshihisa Morishita, Michinori Ogura, Yasuo Morishima, Masayuki Towatari, Yukio Kato, Hideo Inoue, and Hidehiko Saito
Cancer Res 1990 50: 7703-7709. [Abstract] [PDF]  

Immunohistochemical Localization of Parathyroid Hormone-related Protein in Human Breast Cancer

Justine Southby, Mark W. Kissin, Janine A. Danks, John A. Hayman, Jane M. Moseley, Michael A. Henderson, Richard C. Bennett, and T. John Martin
Cancer Res 1990 50: 7710-7716. [Abstract] [PDF]  

Announcements

Cancer Res 1990 50: 7723-7724. [PDF]  

Advances in Brief:

p53 Gene Mutations Occur in Combination with 17p Allelic Deletions as Late Events in Colorectal Tumorigenesis

Suzanne J. Baker, Antonette C. Preisinger, J. Milburn Jessup, Christos Paraskeva, Sanford Markowitz, J. K. V. Willson, Stanley Hamilton, and Bert Vogelstein
Cancer Res 1990 50: 7717-7722. [Abstract] [PDF]  

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