Perspectives in Cancer Research:

The Emerging Biology of Modern Radiation Oncology

Thomas E. Goffman, Andrew Raubitschek, James B. Mitchell, and Eli Glatstein
Cancer Res 1990 50: 7735-7744. [PDF]  

Potentiation by the Hypoxic Cytotoxin SR 4233 of Cell Killing Produced by Fractionated Irradiation of Mouse Tumors

J. Martin Brown and Marilyn J. Lemmon
Cancer Res 1990 50: 7745-7749. [Abstract] [PDF]  

Inhibition of Antibody Response to Pseudomonas Exotoxin and an Immunotoxin Containing Pseudomonas Exotoxin by 15-Deoxyspergualin in Mice

Lee H. Pai, David J. FitzGerald, Mark Tepper, Bernice Schacter, George Spitalny, and Ira Pastan
Cancer Res 1990 50: 7750-7753. [Abstract] [PDF]  

Suramin Affects DNA Synthesis in HeLa Cells by Inhibition of DNA Polymerases

Hitesh K. Jindal, Christopher W. Anderson, Randall G. Davis, and Jamboor K. Vishwanatha
Cancer Res 1990 50: 7754-7757. [Abstract] [PDF]  

Purification and Characterization of Extracellular Matrix-degrading Metalloproteinase, Matrin (Pump-1), Secreted from Human Rectal Carcinoma Cell Line

Kaoru Miyazaki, Yasuhisa Hattori, Fuminori Umenishi, Hidetaro Yasumitsu, and Makoto Umeda
Cancer Res 1990 50: 7758-7764. [Abstract] [PDF]  

Merocyanine 540-sensitized Photoinactivation of Soluble and Membrane-bound Enzymes in L1210 Leukemia Cells

David K. Gaffney and Fritz Sieber
Cancer Res 1990 50: 7765-7769. [Abstract] [PDF]  

Role of Estrogen-induced Insulin-like Growth Factors in the Proliferation of Human Breast Cancer Cells

Bart van der Burg, Linda Isbrücker, Adrie J. P. van Selm-Miltenburg, Siegfried W. de Laat, and Everardus J. J. van Zoelen
Cancer Res 1990 50: 7770-7774. [Abstract] [PDF]  

Site-dependent Differences in Response of the UV-2237 Murine Fibrosarcoma to Systemic Therapy with Adriamycin

Alexander N. Staroselsky, Dominic Fan, Catherine A. O'Brian, Corazon D. Bucana, Krishna P. Gupta, and Isaiah J. Fidler
Cancer Res 1990 50: 7775-7780. [Abstract] [PDF]  

Deletion of -, ß-, and -Interferon Genes in Malignant Cells from Children with Acute Lymphocytic Leukemia

Stefan Einhorn, Dan Grandér, Olle Björk, Karen Bröndum-Nielsen, and Stefan Söderhäll
Cancer Res 1990 50: 7781-7785. [Abstract] [PDF]  

Expression of the Interleukin 6 Receptor and Interleukin 6 in Prostate Carcinoma Cells

Clay B. Siegall, Gisela Schwab, Richard P. Nordan, David J. FitzGerald, and Ira Pastan
Cancer Res 1990 50: 7786-7788. [Abstract] [PDF]  

Activation of Mitomycin C by NADPH:Cytochrome P-450 Reductase

H. Frances J. Bligh, Agnieszka Bartoszek, Craig N. Robson, Ian D. Hickson, Charles B. Kasper, Jean D. Beggs, and C. Roland Wolf
Cancer Res 1990 50: 7789-7792. [Abstract] [PDF]  

Cytotoxic Effects of Dihydroorotase Inhibitors upon Human CCRF-CEM Leukemia

Julie Brooke, Eve Szabados, Stephen D. Lyons, Richard J. Goodridge, Michael C. Harsanyi, Anthony Poiner, and Richard I. Christopherson
Cancer Res 1990 50: 7793-7798. [Abstract] [PDF]  

Characterization of High Specific Activity [16-¹²³I]Iodo-17ß-estradiol as an Estrogen Receptor-specific Radioligand Capable of Imaging Estrogen Receptor-positive Tumors

Edward J. Pavlik, Katherine Nelson, Holly H. Gallion, John R. van Nagell, Jr., Elvis S. Donaldson, W. J. Shih, Jay A. Spicer, David F. Preston, Richard J. Baranczuk, and Daniel E. Kenady
Cancer Res 1990 50: 7799-7805. [Abstract] [PDF]  

Growth Control of Human Mammary Cancer Cells (MCF-7 Cells) in Culture: Effect of Estradiol and Growth Factors in Serum-containing Medium

Asbjørn Aakvaag, Edle Utaaker, Thor Thorsen, Oscar A. Lea, and Hooshang Lahooti
Cancer Res 1990 50: 7806-7810. [Abstract] [PDF]  

Heterogeneous Protooncogene Amplification Correlates with Tumor Progression and Presence of Metastases in Gastric Cancer Patients

Guglielmina N. Ranzani, Natalia S. Pellegata, Carlo Previderè, Ariele Saragoni, Antonio Vio, Marco Maltoni, and Dino Amadori
Cancer Res 1990 50: 7811-7814. [Abstract] [PDF]  

Occurrence of IgA and IgG Antibodies to Select Peptides Representing Human Papillomavirus Type 16 among Cervical Cancer Cases and Controls

Valerie M. Mann, Suzanne Loo de Lao, Maria Brenes, Louise A. Brinton, J. Alan Rawls, Maurice Green, William C. Reeves, and William E. Rawls
Cancer Res 1990 50: 7815-7819. [Abstract] [PDF]  

Retroviral Vector-mediated -Interferon Gene Transfer into Tumor Cells Generates Potent and Long Lasting Antitumor Immunity

Bernd Gansbacher, Rajat Bannerji, Brian Daniels, Karen Zier, Kathy Cronin, and Eli Gilboa
Cancer Res 1990 50: 7820-7825. [Abstract] [PDF]  

Growth Inhibition of Glioma Cells Transfected with the Human ß-Interferon Gene by Liposomes Coupled with a Monoclonal Antibody

Masaaki Mizuno, Jun Yoshida, Kenichiro Sugita, Itaru Inoue, Hisao Seo, Yutaka Hayashi, Takuya Koshizaka, and Kunio Yagi
Cancer Res 1990 50: 7826-7829. [Abstract] [PDF]  

Differential Expression of Transglutaminase in Human Erythroleukemia Cells in Response to Retinoic Acid

T. Suedhoff, P. J. Birckbichler, K. N. Lee, E. Conway, and M. K. Patterson, Jr.
Cancer Res 1990 50: 7830-7834. [Abstract] [PDF]  

Role of Valence State and Solubility of Chromium Compounds on Induction of Cytotoxicity, Mutagenesis, and Anchorage Independence in Diploid Human Fibroblasts

Kim A. Biedermann and Joseph R. Landolph
Cancer Res 1990 50: 7835-7842. [Abstract] [PDF]  

-Fetoprotein in the Woodchuck Model of Hepadnavirus Infection and Disease: Normal Physiological Patterns and Responses to Woodchuck Hepatitis Virus Infection and Hepatocellular Carcinoma

Paul J. Cote, John L. Gerin, and Bud C. Tennant
Cancer Res 1990 50: 7843-7851. [Abstract] [PDF]  

Effect of Hexamethylene Bisacetamide and Cyclosporin A on Recovery of Herpes Simplex Virus Type 2 from the in Vitro Model of Latency in a Human Neuroblastoma Cell Line

Yasuo Kondo, Yoshiaki Yura, Hiroki Iga, Tetsuo Yanagawa, Hideo Yoshida, Nanayo Furumoto, and Mitsunobu Sato
Cancer Res 1990 50: 7852-7857. [Abstract] [PDF]  

Progestins Increase Insulin Receptor Content and Insulin Stimulation of Growth in Human Breast Carcinoma Cells

Vincenzo Papa, Constance C. Reese, Antonio Brunetti, Riccardo Vigneri, Pentti K. Sitteri, and Ira D. Goldfine
Cancer Res 1990 50: 7858-7862. [Abstract] [PDF]  

Role of Reactive Nitrogen Intermediate Production in Alveolar Macrophage-mediated Cytostatic Activity Induced by Bleomycin Lung Damage in Rats

Anne E. Huot and Miles P. Hacker
Cancer Res 1990 50: 7863-7866. [Abstract] [PDF]  

Cytotoxicity of Lonidamine Alone and in Combination with Other Drugs against Murine RIF-1 and Human HT1080 Cells in Vitro

Shoucheng Ning and George M. Hahn
Cancer Res 1990 50: 7867-7870. [Abstract] [PDF]  

Induction of Glutathione Transferases and NAD(P)H:Quinone Reductase by Fumaric Acid Derivatives in Rodent Cells and Tissues

Sharon R. Spencer, Cynthia A. Wilczak, and Paul Talalay
Cancer Res 1990 50: 7871-7875. [Abstract] [PDF]  

Mitochondrial Toxicity of Cationic Photosensitiziers for Photochemotherapy

Josephine S. Modica-Napolitano, John L. Joyal, Gulshan Ara, Allan R. Oseroff, and June R. Aprille
Cancer Res 1990 50: 7876-7881. [Abstract] [PDF]  

Interaction of Vasopressin and Oxytocin with Human Breast Carcinoma Cells

A. H. Taylor, V. T. Y. Ang, J. S. Jenkins, J. J. Silverlight, R. C. Coombes, and Y. A. Luqmani
Cancer Res 1990 50: 7882-7886. [Abstract] [PDF]  

Kinetics of the Formation and Removal of Cisplatin-DNA Adducts in Blood Cells and Tumor Tissue of Cancer Patients Receiving Chemotherapy: Comparison with in Vitro Adduct Formation

Anne Marie J. Fichtinger-Schepman, Saskia D. van der Velde-Visser, Helma C. M. van Dijk-Knijnenburg, Allan T. van Oosterom, Robert A. Baan, and Frits Berends
Cancer Res 1990 50: 7887-7894. [Abstract] [PDF]  

Sequential Emergence of Distinct Resistance Phenotypes in Murine Erythroleukemia Cells under Adriamycin Selection: Decreased Anthracycline Uptake Precedes Increased P-Glycoprotein Expression

Christopher A. Slapak, Janice C. Daniel, and Stuart B. Levy
Cancer Res 1990 50: 7895-7901. [Abstract] [PDF]  

Myxoid Liposarcoma with t(12;16) (q13;p11) Contains Site-specific Differences in Methylation Patterns Surrounding a Zinc-Finger Gene Mapped to the Breakpoint Region on Chromosome 12

Sylvie Paulien, Claude Turc-Carel, Paola Dal Cin, Sheila Jani-Sait, Chandrika Sreekantaiah, Stanley P. L. Leong, Bert Vogelstein, Kenneth W. Kinzler, Avery A. Sandberg, and Robert M. Gemmill
Cancer Res 1990 50: 7902-7907. [Abstract] [PDF]  

Expression of the O⁶-Methylguanine-DNA Methyltransferase Gene MGMT in MER⁺ and MER^- Human Tumor Cells

Albert J. Fornace, Jr., Mathilda A. Papathanasiou, M. Christine Hollander, and Daniel B. Yarosh
Cancer Res 1990 50: 7908-7911. [Abstract] [PDF]  

DNA in Situ Sensitivity to Denaturation in Bladder Cancer and Its Correlation with Tumor Stage

P. R. Bretton, Z. Darzynkiewicz, E. Henry, M. Kimmel, W. R. Fair, and M. R. Melamed
Cancer Res 1990 50: 7912-7914. [Abstract] [PDF]  

Pharmacokinetics and Metabolism of Cyclopentenyl Cytosine in Nonhuman Primates

Susan M. Blaney, Frank M. Balis, Lajos Hegedus, Richard L. Heideman, Cynthia McCully, Robert F. Murphy, James A. Kelley, and David G. Poplack
Cancer Res 1990 50: 7915-7919. [Abstract] [PDF]  

Relationship of Polymorphisms near the Rat Prolactin, N-ras, and Retinoblastoma Genes with Susceptibility to Estrogen-induced Pituitary Tumors

Laurie A. Shepel and Jack Gorski
Cancer Res 1990 50: 7920-7925. [Abstract] [PDF]  

Systemic Alkalinization Inhibits the Ability of Flavone Acetic Acid to Augment Natural Killer Activity, Induce Cytokine Gene Expression, and Synergize with Interleukin 2 for the Treatment of Murine Renal Cancer

Hitoyasu Futami, Ronald L. Hornung, Timothy T. Back, Robert Bull, Eilene Gruys, and Robert H. Wiltrout
Cancer Res 1990 50: 7926-7931. [Abstract] [PDF]  

Epidermal Growth Factor Inhibits Transiently the Progression from G₂-Phase to Mitosis: A Receptor-mediated Phenomenon in Various Cells

Volker Kinzel, Marietta Kaszkin, Annegret Blume, and James Richards
Cancer Res 1990 50: 7932-7936. [Abstract] [PDF]  

Epithelial Cell Kinetics in the Remaining Colorectal Mucosa after Surgery for Cancer of the Large Bowel

Alessandra Scalmati, Luca Roncucci, Giorgio Ghidini, Guido Biasco, and Maurizio Ponz de Leon
Cancer Res 1990 50: 7937-7941. [Abstract] [PDF]  

Purification of Hepatic Polymorphic Arylamine N-Acetyltransferase from Homozygous Rapid Acetylator Inbred Hamster: Identity with Polymorphic N-Hydroxyarylamine-O-Acetyltransferase

Alma Trinidad, David W. Hein, Timothy D. Rustan, Ronald J. Ferguson, Linda S. Miller, Kyle D. Bucher, Ward G. Kirlin, Fredrick Ogolla, and Allen F. Andrews
Cancer Res 1990 50: 7942-7949. [Abstract] [PDF]  

Frequency and Structure of p53 Rearrangements in Human Osteosarcoma

Carl W. Miller, Abdulkarim Aslo, Cassidy Tsay, Dennis Slamon, Kanji Ishizaki, Junya Toguchida, Takao Yamamuro, Beatrice Lampkin, and H. Phillip Koeffler
Cancer Res 1990 50: 7950-7954. [Abstract] [PDF]  

Up-Regulation of Transferrin Receptor Gene Expression by Granulocyte Colony-stimulating Factor in Human Myeloid Leukemia Cells

Yoshihisa Morishita, Takae Kataoka, Masayuki Towatari, Takahiko Ito, Hideo Inoue, Michinori Ogura, Yasuo Morishima, and Hidehiko Saito
Cancer Res 1990 50: 7955-7961. [Abstract] [PDF]  

Elevated Expression of DNA Topoisomerase II in Camptothecin-resistant Human Tumor Cell Lines

Yoshikazu Sugimoto, Satomi Tsukahara, Tomoko Oh-hara, Leroy F. Liu, and Takashi Tsuruo
Cancer Res 1990 50: 7962-7965. [Abstract] [PDF]  

Ditercalinium, a Nucleic Acid Binder, Inhits the Respiratory Chain of Isolated Mammalian Mitochondria

Jacques Dupont, Marc-Antoine Schwaller, and Guy Dodin
Cancer Res 1990 50: 7966-7972. [Abstract] [PDF]  

Biodistribution, Pharmacokinetic, and Imaging Studies with ¹⁸⁶Re-labeled NR-LU-10 Whole Antibody in LS174T Colonic Tumor-bearing Mice

M. H. Goldrosen, W. C. Biddle, J. Pancook, S. Bakshi, J-L. Vanderheyden, A. R. Fritzberg, A. C. Morgan, Jr., and K. A. Foon
Cancer Res 1990 50: 7973-7978. [Abstract] [PDF]  

Spontaneous Abnormalities in Normal Fibroblasts from Patients with Li-Fraumeni Cancer Syndrome: Aneuploidy and Immortalization

Farideh Z. Bischoff, Sun O. Yim, Sen Pathak, Grace Grant, Michael J. Siciliano, B. C. Giovanella, Louise C. Strong, and Michael A. Tainsky
Cancer Res 1990 50: 7979-7984. [Abstract] [PDF]  

Glucocorticoid Receptor Monoclonal Antibodies Define the Biological Action of RU 38486 in Intact B16 Melanoma Cells

Rochelle G. Lindemeyer, Noreen M. Robertson, and Gerald Litwack
Cancer Res 1990 50: 7985-7991. [Abstract] [PDF]  

Mutagenesis of Mouse Intestine in Vivo Using the Dlb-1 Specific Locus Test: Studies with 1,2-Dimethylhydrazine, Dimethylnitrosamine, and the Dietary Mutagen 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline

Douglas J. Winton, Nigel J. Gooderham, Alan R. Boobis, Donald S. Davies, and Bruce A. J. Ponder
Cancer Res 1990 50: 7992-7996. [Abstract] [PDF]  

Suppression of Wound Healing in Tumor Bearing Animals as a Model for Tumor-Host Interaction: Mechanism of Suppression

Robert A. Gatenby and Douglas D. Taylor
Cancer Res 1990 50: 7997-8001. [Abstract] [PDF]  

Expression of ERBB2 in Human Gastric Carcinomas: Relationship between p185^ERBB2 Expression and the Gene Amplification

Takashi Kameda, Wataru Yasui, Kazuhiro Yoshida, Tetsuhiro Tsujino, Hirofumi Nakayama, Masanori Ito, Hisao Ito, and Eiichi Tahara
Cancer Res 1990 50: 8002-8009. [Abstract] [PDF]  

Interaction of Fibrinogen with Murine Melanoma Cells: Covalent Association with Cell Membranes and Protection against Recognition by Lymphokine-activated Killer Cells

Massimo Cardinali, Ryojin Uchino, and Soo Il Chung
Cancer Res 1990 50: 8010-8016. [Abstract] [PDF]  

Characterization of the Epidermal Growth Factor Receptor in Human Glioma Cell Lines and Xenografts

Sandra H. Bigner, Peter A. Humphrey, Albert J. Wong, Bert Vogelstein, Joachim Mark, Henry S. Friedman, and Darell D. Bigner
Cancer Res 1990 50: 8017-8022. [Abstract] [PDF]  

Reduced Expression of HLA Class I and II Antigens in Colon Cancer

Carl J. McDougall, Sing Shang Ngoi, Ira S. Goldman, Thomas Godwin, Juan Felix, Jerome J. DeCosse, and Basil Rigas
Cancer Res 1990 50: 8023-8027. [Abstract] [PDF]  

Interleukin 4 and -Interferon May Play a Role in the Histopathogenesis of Peripheral T-Cell Lymphoma

Kazunori Ohnishi, Atsushi Ichikawa, Yoshitoyo Kagami, Tetsuro Nagasaka, Tamikazu Niwa, Tomomitsu Hotta, and Hidehiko Saito
Cancer Res 1990 50: 8028-8033. [Abstract] [PDF]  

Letter to Editor:

Note re: July 1, 1990 Cover of Cancer Research

Ludwik Gross
Cancer Res 1990 50: 8034 [PDF]  

Articles:

Announcements

Cancer Res 1990 50: 8035-8036. [PDF]  

Acknowledgment to Reviewers

Cancer Res 1990 50: 8037-8046. [PDF]  

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