Molecular Biology and Genetics:

Loss of Heterozygosity for Loci on the Long Arm of Chromosome 6 in Human Malignant Melanoma

D. Millikin, E. Meese, B. Vogelstein, C. Witkowski, and J. Trent
Cancer Res 1991 51: 5449-5453. [Abstract] [PDF]  

17p Allelic Deletions and p53 Protein Overexpression in Barrett's Adenocarcinoma

Patricia L. Blount, Stig Ramel, Wendy H. Raskind, Rodger C. Haggitt, Carissa A. Sanchez, Patrick J. Dean, Peter S. Rabinovitch, and Brian J. Reid
Cancer Res 1991 51: 5482-5486. [Abstract] [PDF]  

c-myc Gene-induced Alterations in Protein Kinase C Expression: A Possible Mechanism Facilitating myc-ras Gene Complementation

Linda F. Barr, Mack Mabry, Barry D. Nelkin, Greg Tyler, W. Stratford May, and Stephen B. Baylin
Cancer Res 1991 51: 5514-5519. [Abstract] [PDF]  

Aberrations of the Tumor Suppressor p53 and Retinoblastoma Genes in Human Hepatocellular Carcinomas

Yoshinori Murakami, Kenshi Hayashi, Setsuo Hirohashi, and Takao Sekiya
Cancer Res 1991 51: 5520-5525. [Abstract] [PDF]  

Induction of Tissue-type Plasminogen Activator by Ionizing Radiation in Human Malignant Melanoma Cells

David A. Boothman, Meizhi Wang, and Sam W. Lee
Cancer Res 1991 51: 5587-5595. [Abstract] [PDF]  

Structure and Expression of the ß-Platelet-derived Growth Factor Receptor Gene in Human Tumor Cell Lines

Rajesh Malik, Mohan Gope, Richard B. Womer, Thandavarayan Nagashunmugam, Judith F. Margolin, Amitabha Basu, and Charles D. Scher
Cancer Res 1991 51: 5626-5631. [Abstract] [PDF]  

Allelic Loss on Chromosome 17p and p53 Mutations in Human Endometrial Carcinoma of the Uterus

Aikou Okamoto, Yuichi Sameshima, Yukishige Yamada, Shin-ichi Teshima, Yoshiteru Terashima, Masaaki Terada, and Jun Yokota
Cancer Res 1991 51: 5632-5635. [Abstract] [PDF]  

Frequent Induction of Mammary Carcinomas following neu Oncogene Transfer into in Situ Mammary Epithelial Cells of Susceptible and Resistant Rat Strains

Bingcheng Wang, Wendy S. Kennan, Jane Yasukawa-Barnes, Mary J. Lindstrom, and Michael N. Gould
Cancer Res 1991 51: 5649-5654. [Abstract] [PDF]  

Inactivation of the Retinoblastoma Gene in Human Bladder and Renal Cell Carcinomas

Jiro Ishikawa, Hong-Ji Xu, Shi-Xue Hu, David W. Yandell, Sakan Maeda, Sadao Kamidono, William F. Benedict, and Rei Takahashi
Cancer Res 1991 51: 5736-5743. [Abstract] [PDF]  

Preclinical Pharmacology and Experimental Therapeutics:

Potentiation of Mitomycin C and Porfiromycin Antitumor Activity in Solid Tumor Models by Recombinant Human Interleukin 1

Paul G. Braunschweiger, Steven A. Jones, Candace S. Johnson, and Philip Furmanski
Cancer Res 1991 51: 5454-5460. [Abstract] [PDF]  

Pharmacokinetics of Pyrazoloacridine in the Rhesus Monkey

Stacey L. Berg, Frank M. Balis, Cynthia L. McCully, Karen S. Godwin, and David G. Poplack
Cancer Res 1991 51: 5467-5470. [Abstract] [PDF]  

Epidermal Growth Factor Receptor-reactive Monoclonal Antibodies: Xenograft Antitumor Activity Alone and as Drug Immunoconjugates

Magda C. Gutowski, Stephen L. Briggs, and David A. Johnson
Cancer Res 1991 51: 5471-5475. [Abstract] [PDF]  

Membrane Transport of Natural Folates and Antifolate Compounds in Murine L1210 Leukemia Cells: Role of Carrier- and Receptor-mediated Transport Systems

G. Robbin Westerhof, Gerrit Jansen, Nancy van Emmerik, Ietje Kathmann, Gert Rijksen, Ann L. Jackman, and Jan H. Schornagel
Cancer Res 1991 51: 5507-5513. [Abstract] [PDF]  

Effects of Recombinant -Interferon-Gelatin Conjugate on in Vivo Murine Tumor Cell Growth

Yasuhiko Tabata, Kazuko Uno, Tetsuji Yamaoka, Yoshito Ikada, and Shigeru Muramatsu
Cancer Res 1991 51: 5532-5538. [Abstract] [PDF]  

ICI D1694, a Quinazoline Antifolate Thymidylate Synthase Inhibitor That Is a Potent Inhibitor of L1210 Tumor Cell Growth in Vitro and in Vivo: A New Agent for Clinical Study

Ann L. Jackman, Gordon A. Taylor, William Gibson, Rosemary Kimbell, Melody Brown, A. Hilary Calvert, Ian R. Judson, and Leslie R. Hughes
Cancer Res 1991 51: 5579-5586. [Abstract] [PDF]  

Immunology:

Pharmacokinetics and Immune Response of ¹³¹I-Chimeric Mouse/Human B72.3 (Human 4) Monoclonal Antibody in Humans

M. B. Khazaeli, Mansoor N. Saleh, T. P. Liu, Ruby F. Meredith, Richard H. Wheeler, Terry S. Baker, David King, David Secher, Laquetta Allen, Kim Rogers, David Colcher, Jeffrey Schlom, Dan Shochat, and Albert F. LoBuglio
Cancer Res 1991 51: 5461-5466. [Abstract] [PDF]  

Down-regulation by Interleukin 4 of Activation of Human Alveolar Macrophages to the Tumoricidal State

Yasuhiko Nishioka, Saburo Sone, Etsuko Orino, Akihiko Nii, and Takeshi Ogura
Cancer Res 1991 51: 5526-5531. [Abstract] [PDF]  

T-Cell Receptor Vß Gene Expression Differs in Tumor-infiltrating Lymphocytes within Primary and Metastatic Melanoma

Taizo Nitta, Robert Bell, Ko Okumura, Kiyoshi Sato, and Lawrence Steinman
Cancer Res 1991 51: 5565-5569. [Abstract] [PDF]  

Phenotype and Function of Natural Killer Cells in Patients with Bronchogenic Carcinoma

Ann V. LeFever and Akira Funahashi
Cancer Res 1991 51: 5596-5601. [Abstract] [PDF]  

Increased Serum Levels of Soluble Receptors for Tumor Necrosis Factor in Cancer Patients

Dan Aderka, Hartmut Engelmann, Vered Hornik, Yehuda Skornick, Yoram Levo, David Wallach, and Gil Kushtai
Cancer Res 1991 51: 5602-5607. [Abstract] [PDF]  

Identification of a Novel Tumor-associated M_r 110,000 Gene Product in Human Gastric Carcinoma Cells That Is Immunologically Related to Carcinoembryonic Antigen

Shinya Shimada, Michio Ogawa, Jeffrey Schlom, and John W. Greiner
Cancer Res 1991 51: 5694-5703. [Abstract] [PDF]  

Human T-Lymphocytes Targeted against an Established Human Ovarian Carcinoma with a Bispecific F(ab')₂ Antibody Prolong Host Survival in a Murine Xenograft Model

Delia Mezzanzanica, Maria A. Garrido, Donald S. Neblock, Peter E. Daddona, Sarah M. Andrew, Vincent R. Zurawski, Jr., David M. Segal, and John R. Wunderlich
Cancer Res 1991 51: 5716-5721. [Abstract] [PDF]  

Human Colonic Sulfomucin Identified by a Specific Monoclonal Antibody

Tatsuro Irimura, Dianna M. Wynn, Leah G. Hager, Karen R. Cleary, and David M. Ota
Cancer Res 1991 51: 5728-5735. [Abstract] [PDF]  

Immunohistochemical and Pharmacokinetic Characterization of Site-specific Immunoconjugate 15A8-Glycyl-tyrosyl-(N--diethylenetriamine Pentaacetic Acid)-lysine Derived from Anti-Breast Carcinoma Monoclonal Antibody 15A8

Maurice J. Rosenstraus, Wendy L. Davis, A. Dwight Lopes, Christopher J. D'Aleo, and Steven C. Gilman
Cancer Res 1991 51: 5744-5751. [Abstract] [PDF]  

Endocrinology:

Transforming Growth Factor Gene Expression in Human Endometrial Adenocarcinoma Cells: Regulation by Progestins

Yuewen Gong, Yuzuru Anzai, Leigh C. Murphy, Gustavo Ballejo, Christian F. Holinka, Erlio Gurpide, and Liam J. Murphy
Cancer Res 1991 51: 5476-5481. [Abstract] [PDF]  

Insensitivity to the Cytolytic Effects of Glucocorticoids in Vivo Is Associated with a Novel "Slow Death" Phenotype

E. Aubrey Thompson
Cancer Res 1991 51: 5544-5550. [Abstract] [PDF]  

Glucocorticoid Insensitivity of P1798 Lymphoma Cells Is Associated with Production of a Factor That Attenuates the Lytic Response

E. Aubrey Thompson
Cancer Res 1991 51: 5551-5556. [Abstract] [PDF]  

Inhibition of Murine Transformed Leydig Cell Proliferation by Leukotrienes in Serum-free Culture

Kazumasa Nishii, Yasuko Nishizawa, Yoshio Nishizawa, Keishi Matsumoto, and Bunzo Sato
Cancer Res 1991 51: 5573-5578. [Abstract] [PDF]  

Carcinogenesis:

Tumor-promoting Effect of Urinary Epidermal Growth Factor in Rat Urinary Bladder Carcinogenesis

Hitoshi Momose, Hiroaki Kakinuma, Sabeeha Y. Shariff, Glen B. Mitchell, Alfred Rademaker, and Ryoichi Oyasu
Cancer Res 1991 51: 5487-5490. [Abstract] [PDF]  

Quantitation of Microsomal -Hydroxylation of the Tobacco-specific Nitrosamine, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone

Lisa A. Peterson, Rachel Mathew, and Stephen S. Hecht
Cancer Res 1991 51: 5495-5500. [Abstract] [PDF]  

Protection against Aflatoxin B₁-induced Hepatocarcinogenesis in F344 Rats by 5-(2-Pyrazinyl)-4-methyl-1,2-dithiole-3-thione (Oltipraz): Predictive Role for Short-Term Molecular Dosimetry

B. D. Roebuck, Yi-Liang Liu, Adrianne E. Rogers, John D. Groopman, and Thomas W. Kensler
Cancer Res 1991 51: 5501-5506. [Abstract] [PDF]  

O⁶-Methylguanine Is a Critical Determinant of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Tumorigenesis in A/J Mouse Lung

Lisa A. Peterson and Stephen S. Hecht
Cancer Res 1991 51: 5557-5564. [Abstract] [PDF]  

Dietary Calcium and Vitamin D Modulate 1,2-Dimethylhydrazine-induced Colonic Carcinogenesis in the Rat

Michael D. Sitrin, Allan G. Halline, Cyril Abrahams, and Thomas A. Brasitus
Cancer Res 1991 51: 5608-5613. [Abstract] [PDF]  

Formation and Persistence of DNA Adducts of 2-Amino-3-methylimidazo[4,5-f] quinoline in Male Fischer-344 Rats

Hong-Xiang Zu and Herman A. J. Schut
Cancer Res 1991 51: 5636-5641. [Abstract] [PDF]  

Tumor-promoting Activity of Ethyl Phenylpropiolate

Gregory S. Cameron, James K. Baldwin, Richard C. Klann, Kelly E. Patrick, and Susan M. Fischer
Cancer Res 1991 51: 5642-5648. [Abstract] [PDF]  

Forestomach and Kidney Carcinogenicity of Caffeic Acid in F344 Rats and C57BL/6N x C3H/HeN F₁ Mice

Akihiro Hagiwara, Masao Hirose, Satoru Takahashi, Kumiko Ogawa, Tomoyuki Shirai, and Nobuyuki Ito
Cancer Res 1991 51: 5655-5660. [Abstract] [PDF]  

Phenotypic Characterization of Metaplastic Intestinal Glands and Ductular Hepatocytes in Cholangiofibrotic Lesions Rapidly Induced in the Caudate Liver Lobe of Rats Treated with Furan

Lynne W. Elmore and Alphonse E. Sirica
Cancer Res 1991 51: 5752-5759. [Abstract] [PDF]  

Tumor Biology:

Differential Expression of Transforming Growth Factor-ß1 Gene in 3LL Metastatic Variants

Danilo Perrotti, Letizia Cimino, Sergio Ferrari, and Ada Sacchi
Cancer Res 1991 51: 5491-5494. [Abstract] [PDF]  

Use and Mechanism of Action of AS101 in Protecting Bone Marrow Colony Forming Units-Granulocyte-Macrophage following Purging with ASTA-Z 7557

Yona Kalechman, Iris Sotnik Barkai, Michael Albeck, Gary Horwith, Suren N. Sehagl, and Benjamin Sredni
Cancer Res 1991 51: 5614-5620. [Abstract] [PDF]  

Extracellular Matrix and the Patterns of Differentiation of Human Endometrial Carcinomas in Vitro and in Vivo

P. G. Satyaswaroop and S. S. Tabibzadeh
Cancer Res 1991 51: 5661-5666. [Abstract] [PDF]  

Laminin Receptor Complementary DNA-deduced Synthetic Peptide Inhibits Cancer Cell Attachment to Endothelium

Vincent Gastronovo, Giulia Taraboletti, and Mark E. Sobel
Cancer Res 1991 51: 5672-5678. [Abstract] [PDF]  

Carcinoembryonic Antigen Has a Different Molecular Weight in Normal Colon and in Cancer Cells due to N-Glycosylation Differences

M. Garcia, C. Seigner, C. Bastid, R. Choux, M. J. Payan, and H. Reggio
Cancer Res 1991 51: 5679-5686. [Abstract] [PDF]  

Interleukin 4 Alone and with -Interferon or -Tumor Necrosis Factor Inhibits Cell Growth and Modulates Cell Surface Antigens on Human Renal Cell Carcinomas

Dave S. B. Hoon, Edward Okun, Marienelle Banez, Reiko F. Irie, and Donald L. Morton
Cancer Res 1991 51: 5687-5693. [Abstract] [PDF]  

Human Malignant Histiocytosis CD30+ DEL Cell Line Differentiates into Macrophage-like Cells When Treated with a Phorbol Diester

Jean Gogusev, Sylvette Barbey, and Christian Nezelof
Cancer Res 1991 51: 5712-5715. [Abstract] [PDF]  

Androgen Sensitivity of the New Human Breast Cancer Cell Line MFM-223

Reinhard Hackenberg, Susanne Lüttchens, Jürgen Hofmann, Regina Kunzmann, Fritz Hölzel, and Klaus-Dieter Schulz
Cancer Res 1991 51: 5722-5727. [Abstract] [PDF]  

Acidic and Basic Fibrolast Growth Factors Are Present in Glioblastoma Multiforme

David F. Stefnik, Laila R. Rizkalla, Anuradha Soi, Sidney A. Goldblatt, and Waheeb M. Rizkalla
Cancer Res 1991 51: 5760-5765. [Abstract] [PDF]  

Biochemistry and Biophysics:

Human Fibroblasts Contain a Proteolytic Activity Which Is Inhibited by the Bowman-Birk Protease Inhibitor

Paul C. Billings, Joan M. Habres, David C. Liao, and Stephen W. Tuttle
Cancer Res 1991 51: 5539-5543. [Abstract] [PDF]  

Clinical:

On the Pharmacokinetics of 2-Chloro-2'-deoxyadenosine in Humans

Jan Liliemark and Gunnar Juliusson
Cancer Res 1991 51: 5570-5572. [Abstract] [PDF]  

Evaluation of Nontumorous Tissue Damage by Transcatheter Arterial Embolization for Hepatocellular Carcinoma

Khaleque Newaz Khan, Keisuke Nakata, Yukio Kusumoto, Masayoshi Shima, Nobuko Ishii, Toshihiko Koji, and Shigenobu Nagataki
Cancer Res 1991 51: 5667-5671. [Abstract] [PDF]  

Comparison of Immunoscintigraphy and Computerized Tomography in Identifying Colorectal Cancer: Individual Lesion Analysis

Raffael M. Corbisiero, Dave M. Yamauchi, Lawrence E. Williams, Jose M. Esteban, Tamara Odom-Maryon, and J. David Beatty
Cancer Res 1991 51: 5704-5711. [Abstract] [PDF]  

Epidemiological:

Association between Hepatitis C Virus Antibodies and Hepatocellular Carcinoma in Taiwan

Ming-Whei Yu, San-Lin You, Ah-Seng Chang, Shang-Nan Lu, Yun-Fang Liaw, and Chien-Jen Chen
Cancer Res 1991 51: 5621-5625. [Abstract] [PDF]  

Advances in Brief:

Frequent Loss of Heterozygosity at the Retinoblastoma Locus in Human Esophageal Cancers

Robert F. Boynton, Ying Huang, Patricia L. Blount, Brian J. Reid, Wendy H. Raskind, Rodger C. Haggitt, Carnell Newkirk, James H. Resau, Jing Yin, Tim McDaniel, and Stephen J. Meltzer
Cancer Res 1991 51: 5766-5769. [Abstract] [PDF]  

pH Dependence of 5-Fluorouracil Uptake Observed by in Vivo ³¹P and ¹⁹F Nuclear Magnetic Resonance Spectroscopy

Jean-Luc Guerquin-Kern, François Leteurtre, Alain Croisy, and Jean-Marc Lhoste
Cancer Res 1991 51: 5770-5773. [Abstract] [PDF]  

Induction of Immunogenicity of Monoclonal Antibodies by Conjugation with Drugs

David A. Johnson, Russell L. Barton, Daniel V. Fix, William L. Scott, and Magda C. Gutowski
Cancer Res 1991 51: 5774-5776. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1991 51: 5777-5778. [PDF]  

Calendar of Events

Cancer Res 1991 51: 5778-5779. [PDF]  

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