Perspectives in Cancer Research:

Carcinogenesis and Cancer: Different Perspectives on the Same Disease

Michael B. Sporn
Cancer Res 1991 51: 6215-6218. [PDF]  

Articles:

Analysis of N-Methyl-N-nitrosourea-induced Mutations in a Shuttle Vector Plasmid Propagated in Mouse O⁶-Methylguanine-DNA Methyltransferase-deficient Cells in Comparison with Proficient Cells

Shin-ichi Moriwaki, Takashi Yagi, Chikako Nishigori, Sadao Imamura, and Hiraku Takebe
Cancer Res 1991 51: 6219-6223. [Abstract] [PDF]  

Modulation by Butylated Hydroxytoluene of Liver and Bladder Carcinogenesis Induced by Chronic Low-Level Exposure to 2-Acetylaminofluorene

Gary M. Williams, Takuji Tanaka, Hiroshi Maruyama, Yoshiichi Maeura, John H. Weisburger, and Edith Zang
Cancer Res 1991 51: 6224-6230. [Abstract] [PDF]  

Immunological Quantitation of Levels of Tissue Inhibitor of Metalloproteinase-1 in Human Colon Cancer

Xiaoqing Lu, Miriam Levy, I. Bernard Weinstein, and Regina M. Santella
Cancer Res 1991 51: 6231-6235. [Abstract] [PDF]  

An Immunotoxin Prepared with Blocked Ricin: A Natural Plant Toxin Adapted for Therapeutic Use

John M. Lambert, Victor S. Goldmacher, Albert R. Collinson, Lee M. Nadler, and Walter A. Blättler
Cancer Res 1991 51: 6236-6242. [Abstract] [PDF]  

Differential Binding and Biological Activities of Epidermal Growth Factor and Transforming Growth Factor in a Human Pancreatic Cancer Cell Line

Murray Korc, Bysani Chandrasekar, and Gul N. Shah
Cancer Res 1991 51: 6243-6249. [Abstract] [PDF]  

Predictive Value of Interleukin-6 and Neopterin in Patients with Multiple Myeloma

Gilbert Reibnegger, Michael Krainer, Manfred Herold, Heinz Ludwig, Helmut Wachter, and Heinz Huber
Cancer Res 1991 51: 6250-6253. [Abstract] [PDF]  

Activation of the Autocrine Transforming Growth Factor Pathway in Human Squamous Carcinoma Cells

Michael Reiss, Ellen B. Stash, Vincent F. Vellucci, and Zhao-ling Zhou
Cancer Res 1991 51: 6254-6262. [Abstract] [PDF]  

Effects of 8-Chloroadenosine 3',5'-Monophosphate and N⁶-Benzyl-Cyclic Adenosine 5'-Monophosphate on Cell Cycle Kinetics of HL-60 Leukemia Cells

Stefano Pepe, Giampaolo Tortora, Philip D. Noguchi, Gerald E. Marti, Glenelle C. Washington, and Yoon S. Cho-Chung
Cancer Res 1991 51: 6263-6267. [Abstract] [PDF]  

A Phase I Clinical and Pharmacokinetic Trial of Hepsulfam

Peter M. Ravdin, Kathy A. Havlin, Milton V. Marshall, Thomas D. Brown, James M. Koeller, John G. Kuhn, Gladys Rodriguez, and Daniel D. Von Hoff
Cancer Res 1991 51: 6268-6272. [Abstract] [PDF]  

Hydroxyurea Accelerates Loss of Extrachromosomally Amplified Genes from Tumor Cells

Daniel D. Von Hoff, Tracey Waddelow, Barbara Forseth, Karen Davidson, Jeff Scott, and Geoffrey Wahl
Cancer Res 1991 51: 6273-6279. [Abstract] [PDF]  

Differential Induction of Secondary DNA Fragmentation by Topoisomerase II Inhibitors in Human Tumor Cell Lines with Amplified c-myc Expression

Richard Bertrand, Monica Sarang, Jeffrey Jenkin, Donna Kerrigan, and Yves Pommier
Cancer Res 1991 51: 6280-6285. [Abstract] [PDF]  

Effect of Antitumor Diarylsulfonylureas on in Vivo and in Vitro Mitochondrial Structure and Functions

Jay H. Thakar, Christian Chapin, R. Howard Berg, Richard A. Ashmun, and Peter J. Houghton
Cancer Res 1991 51: 6286-6291. [Abstract] [PDF]  

Predominance of the Metastatic Phenotype in Somatic Cell Hybrids of the K-1735 Murine Melanoma

Alexander H. Staroselsky, Sen Pathak, Yuti Chernajovsky, Susan L. Tucker, and Isaiah J. Fidler
Cancer Res 1991 51: 6292-6298. [Abstract] [PDF]  

Quantitative Analysis of Genetic Susceptibility to Liver and Lung Carcinogenesis in Mice

Tommaso A. Dragani, Giacomo Manenti, and Giuseppe Della Porta
Cancer Res 1991 51: 6299-6303. [Abstract] [PDF]  

Participation of p53 Protein in the Cellular Response to DNA Damage

Michael B. Kastan, Onyinye Onyekwere, David Sidransky, Bert Vogelstein, and Ruth W. Craig
Cancer Res 1991 51: 6304-6311. [Abstract] [PDF]  

Biological Monitoring of Low-Dose Interleukin 2 in Humans: Soluble Interleukin 2 Receptors, Cytokines, and Cell Surface Phenotypes

Enrique Lopez Hänninen, Alfred Körfer, Martin Hadam, Carsten Schneekloth, Iris Dallmann, Thomas Menzel, Hartmut Kirchner, Hubert Poliwoda, and Jens Atzpodien
Cancer Res 1991 51: 6312-6316. [Abstract] [PDF]  

Phase I Pharmacokinetic and Pharmacodynamic Study of a New Anthrapyrazole, CI-937 (DUP937)

Charles Erlichman, Malcolm Moore, Ian G. Kerr, Bradley Wong, Elizabeth Eisenhauer, Benny Zee, and Lloyd R. Whitfield
Cancer Res 1991 51: 6317-6322. [Abstract] [PDF]  

Experimental and Clinical Observations on Hepatic Cryosurgery for Colorectal Metastases

T. S. Ravikumar, Glenn Steele, Jr., Robert Kane, and Vinnie King
Cancer Res 1991 51: 6323-6327. [Abstract] [PDF]  

E-Cadherin Expression in Squamous Cell Carcinomas of Head and Neck: Inverse Correlation with Tumor Dedifferentiation and Lymph Node Metastasis

Jörg H. Schipper, Uwe H. Frixen, Jürgen Behrens, Andreas Unger, Klaus Jahnke, and Walter Birchmeier
Cancer Res 1991 51: 6328-6337. [Abstract] [PDF]  

Differential Expression of N-myc in Phenotypically Distinct Subclones of a Human Neuroblastoma Cell Line

John Foley, Susan L. Cohn, Helen R. Salwen, Daniel Chagnovich, Janet Cowan, Karen L. Mason, and Linda M. Parysek
Cancer Res 1991 51: 6338-6345. [Abstract] [PDF]  

Prognostic Value of Nuclear DNA Content and Expression of the ras Oncogene Product in Lung Cancer

Hiroshi Miyamoto, Masao Harada, Hiroshi Isobe, Hirotoshi D. Akita, Hitoshi Haneda, Etsuro Yamaguchi, Noboru Kuzumaki, and Yoshikazu Kawakami
Cancer Res 1991 51: 6346-6350. [Abstract] [PDF]  

Immunocytochemical Localization of Parathyroid Hormone-like Peptide in the Rat Fetus

R. V. Campos, S. L. Asa, and D. J. Drucker
Cancer Res 1991 51: 6351-6357. [Abstract] [PDF]  

Malignant Behavior and Resistance to Cisplatin of Human Ovarian Carcinoma Xenografts Established from the Same Patient at Different Stages of the Disease

Gabriella Masazza, Valeria Lucchini, Antonella Tomasoni, Fedro Peccatori, Vito Lampasona, Giovanni Giudici, Costantino Mangioni, Andrea Biondi, and Raffaella Giavazzi
Cancer Res 1991 51: 6358-6362. [Abstract] [PDF]  

Construction, Binding Properties, Metabolism, and Tumor Targeting of a Single-Chain Fv Derived from the Pancarcinoma Monoclonal Antibody CC49

D. E. Milenic, T. Yokota, D. R. Filpula, M. A. J. Finkelman, S. W. Dodd, J. F. Wood, M. Whitlow, P. Snoy, and J. Schlom
Cancer Res 1991 51: 6363-6371. [Abstract] [PDF]  

Expression of HLA-A,B,C Antigens on Primary and Metastatic Tumor Cell Populations of Human Carcinomas

Carlos Cordon-Cardo, Zvi Fuks, Marija Drobnjak, Carlos Moreno, Lea Eisenbach, and Michael Feldman
Cancer Res 1991 51: 6372-6380. [Abstract] [PDF]  

Announcements

Cancer Res 1991 51: 6397-6398. [PDF]  

Calendar of Events

Cancer Res 1991 51: 6398-6399. [PDF]  

Advances in Brief:

Intraocular Tumor Suppression of Retinoblastoma Gene-reconstituted Retinoblastoma Cells

Steven A. Madreperla, Judith A. Whittum-Hudson, Robert A. Prendergast, Phang-Lang Chen, and Wen-Hwa Lee
Cancer Res 1991 51: 6381-6384. [Abstract] [PDF]  

A Germ Line Mutation in Exon 5 of the p53 Gene in an Extended Cancer Family

John C. Law, Louise C. Strong, Abirami Chidambaram, and Robert E. Ferrell
Cancer Res 1991 51: 6385-6387. [Abstract] [PDF]  

Demonstration of the Need for End Point Validation of Putative Biomarkers: Failure of Aberrant Crypt Foci to Predict Colon Cancer Incidence

W. Elaine Hardman, Ivan L. Cameron, David W. Heitman, and Edward Contreras
Cancer Res 1991 51: 6388-6392. [Abstract] [PDF]  

p53 Gene Mutations and Abnormal Retinoblastoma Protein in Radiation-induced Human Sarcomas

David G. Brachman, Dennis E. Hallahan, Michael A. Beckett, David W. Yandell, and Ralph R. Weichselbaum
Cancer Res 1991 51: 6393-6396. [Abstract] [PDF]  

Erratum:

Genetic Alterations of the p53 Gene Are a Feature of Malignant Mesotheliomas

Cancer Res 1991 51: 6399 [PDF]  

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