Public Issues:

Training in Clinical Research in Oncology

Brian W. Kimes, Vincent Cairoli, Emil J Freireich, Judith Karp, and Stringner Sue Yang
Cancer Res 1991 51: 753-756. [PDF]  

Perspectives in Cancer Research:

Tumor Transplantation and Tumor Immunity: A Personal View

O. C. A. Scott
Cancer Res 1991 51: 757-763. [PDF]  

Articles:

Induction of in Vitro Differentiation of Mouse Erythroleukemia Cells by Genistein, an Inhibitor of Tyrosine Protein Kinases

Toshio Watanabe, Kazuhiro Kondo, and Michio Oishi
Cancer Res 1991 51: 764-768. [Abstract] [PDF]  

A Role for the Interleukin 1 Receptor in the Synergistic Antitumor Effects of Human Interleukin 1 and Etoposide against Human Melanoma Cells

Noriko Usui, Edward G. Mimnaugh, and Birandra K. Sinha
Cancer Res 1991 51: 769-774. [Abstract] [PDF]  

Heterogeneous Repair of Methylnitrosourea-induced Alkali-labile Sites in Different DNA Sequences

Susan P. LeDoux, Mrudula Thangada, Vilhelm A. Bohr, and Glenn L. Wilson
Cancer Res 1991 51: 775-779. [Abstract] [PDF]  

Lonidamine as a Modulator of Alkylating Agent Activity in Vitro and in Vivo

Beverly A. Teicher, Terence S. Herman, Sylvia A. Holden, Ron Epelbaum, Shi-de Liu, and Emil Frei, III
Cancer Res 1991 51: 780-784. [Abstract] [PDF]  

Enhancement by Methionine Enkephalin of Colon Carcinogenesis Induced by Azoxymethane

Hiroyasu Iishi, Masaharu Tatsuta, Miyako Baba, Shigeru Okuda, and Haruo Taniguchi
Cancer Res 1991 51: 785-788. [Abstract] [PDF]  

Role of Folylpolyglutamates in Biochemical Modulation of Fluoropyrimidines by Leucovorin

Antonella Romanini, James T. Lin, Donna Niedzwiecki, Marlene Bunni, David G. Priest, and Joseph R. Bertino
Cancer Res 1991 51: 789-793. [Abstract] [PDF]  

Production of Large Amounts of Hydrogen Peroxide by Human Tumor Cells

Ted P. Szatrowski and Carl F. Nathan
Cancer Res 1991 51: 794-798. [Abstract] [PDF]  

Multiparametric Flow Cytometry of the Modulation of Tumor Cell Membrane Permeability by Developmental Antitumor Ether Lipid SRI 62-834 in EMT6 Mouse Mammary Tumor and HL-60 Human Promyelocytic Leukemia Cells

Caroline Dive, James V. Watson, and Paul Workman
Cancer Res 1991 51: 799-806. [Abstract] [PDF]  

Hexadecylphosphocholine Inhibits Inositol Phosphate Formation and Protein Kinase C Activity

Florian Überall, Hermann Oberhuber, Karl Maly, John Zaknun, Lars Demuth, and Hans H. Grunicke
Cancer Res 1991 51: 807-812. [Abstract] [PDF]  

Inhibitory Effects of Curcumin on in Vitro Lipoxygenase and Cyclooxygenase Activities in Mouse Epidermis

Mou-Tuan Huang, Thomas Lysz, Thomas Ferraro, Tanveer F. Abidi, Jeffrey D. Laskin, and Allan H. Conney
Cancer Res 1991 51: 813-819. [Abstract] [PDF]  

Allelotype of Renal Cell Carcinoma

Ryoji Morita, Jiro Ishikawa, Masayoshi Tsutsumi, Kazumasa Hikiji, Yutaka Tsukada, Sadao Kamidono, Sakan Maeda, and Yusuke Nakamura
Cancer Res 1991 51: 820-823. [Abstract] [PDF]  

Effects of Phenolic Antioxidants in Low Dose Combination on Forestomach Carcinogenesis in Rats Pretreated with N-Methyl-N'-nitro-N-nitrosoguanidine

Masao Hirose, Mamoru Mutai, Satoru Takahashi, Mayumi Yamada, Shoji Fukushima, and Nobuyuki Ito
Cancer Res 1991 51: 824-827. [Abstract] [PDF]  

Plasma Homocysteine in Children with Acute Lymphoblastic Leukemia: Changes during a Chemotherapeutic Regimen Including Methotrexate

Helga Refsum, Finn Wesenberg, and Per Magne Ueland
Cancer Res 1991 51: 828-835. [Abstract] [PDF]  

Phase I Trial of Natural Human Interferon ß in Metastatic Malignancy

Ronald M. Bukowski, James S. Sergi, William J. Sharfman, G. Thomas Budd, Siva Murthy, Barbara Barna, Sharon V. Medendorp, B. Yen-Lieberman, Vicki Gibson, Laurie Bauer, and Rafael Valenzuela
Cancer Res 1991 51: 836-840. [Abstract] [PDF]  

An ex Vivo Model for the Study of Tumor Metabolism by Nuclear Magnetic Resonance: Characterization of the Phosphorus-31 Spectrum of the Isolated Perfused Morris Hepatoma 7777

Robert A. Graham, Truman R. Brown, and Ronald A. Meyer
Cancer Res 1991 51: 841-849. [Abstract] [PDF]  

4ß- and 4-12-O-Tetradecanoylphorbol-13-acetate Elicit Arachidonate Release from Epidermal Cells through Different Mechanisms

Susan M. Fischer, Kelly E. Patrick, Marilyn L. Lee, and Gregory S. Cameron
Cancer Res 1991 51: 850-856. [Abstract] [PDF]  

Induction of Cytokine Messenger RNA and Secretion in Alveolar Macrophages and Blood Monocytes from Patients with Lung Cancer Receiving Granulocyte-Macrophage Colony-stimulating Factor Therapy

Mary Jane Thomassen, Muzaffar Ahmad, Barbara P. Barna, Joyce Antal, Herbert P. Wiedemann, David P. Meeker, John Klein, Laurie Bauer, Vicki Gibson, Steven Andresen, and Ronald M. Bukowski
Cancer Res 1991 51: 857-862. [Abstract] [PDF]  

Tumor-induced Alterations in Tissue Lipoprotein Lipase Activity and mRNA Levels

Yoshikazu Noguchi, Nadarajen A. Vydelingum, Riad N. Younes, Susan K. Fried, and Murray F. Brennan
Cancer Res 1991 51: 863-869. [Abstract] [PDF]  

Variability of 5-Bromo-2'-deoxyuridine Incorporation into DNA of Human Glioma Cell Lines and Modulation with Fluoropyrimidines

William R. Mancini, Philip L. Stetson, Theodore S. Lawrence, John G. Wagner, Harry S. Greenberg, and William D. Ensminger
Cancer Res 1991 51: 870-874. [Abstract] [PDF]  

In Vivo Activity of Solid Phase Interleukin 2

Edward D. Crum and David R. Kaplan
Cancer Res 1991 51: 875-879. [Abstract] [PDF]  

Effects of Indomethacin, Cytokines, and Cyclosporin A on Tumor Growth and the Subsequent Development of Cancer Cachexia

Johan Gelin, Christer Andersson, and Kent Lundholm
Cancer Res 1991 51: 880-885. [Abstract] [PDF]  

A Cyclophosphamide/DNA Phosphoester Adduct Formed in Vitro and in Vivo

Alexander E. Maccubbin, Lida Caballes, James M. Riordan, Dee H. Huang, and Hira L. Gurtoo
Cancer Res 1991 51: 886-892. [Abstract] [PDF]  

Suppression of Dexamethasone-induced Metallothionein Expression and cis-Diamminedichloroplatinum(II) Resistance by v-mos

Alakananda Basu and John S. Lazo
Cancer Res 1991 51: 893-896. [Abstract] [PDF]  

Solutol HS 15, Nontoxic Polyoxyethylene Esters of 12-Hydroxystearic Acid, Reverses Multidrug Resistance

John S. Coon, Warren Knudson, Kathleen Clodfelter, Bing Lu, and Ronald S. Weinstein
Cancer Res 1991 51: 897-902. [Abstract] [PDF]  

Inhibition of Angiogenesis and Tumor Growth by a Synthetic Laminin Peptide, CDPGYIGSR-NH₂

Noritsugu Sakamoto, Michio Iwahana, Noriko G. Tanaka, and Yasuaki Osada
Cancer Res 1991 51: 903-906. [Abstract] [PDF]  

Effects of Type of Dietary Fat on Phorbol Ester-elicited Tumor Promotion and Other Events in Mouse Skin

Julius Leyton, Marilyn L. Lee, Mary Locniskar, Martha A. Belury, Thomas J. Slaga, David Bechtel, and Susan M. Fischer
Cancer Res 1991 51: 907-915. [Abstract] [PDF]  

Internalization and Action of an Immunotoxin Containing Mistletoe Lectin A-Chain

Antoni Wiedlocha, Kirsten Sandvig, Hermann Walzel, Czeslaw Radzikowsky, and Sjur Olsnes
Cancer Res 1991 51: 916-920. [Abstract] [PDF]  

Suppression of Experimental Lung Colonization of a Metastatic Variant of Murine Colon Adenocarcinoma 26 by a Monoclonal Antibody 8F11 Inhibiting Tumor Cell-induced Platelet Aggregation

Yoshikazu Sugimoto, Masahiko Watanabe, Tomoko Oh-hara, Shigeo Sato, Toshiyuki Isoe, and Takashi Tsuruo
Cancer Res 1991 51: 921-925. [Abstract] [PDF]  

Characterization of the Colorectal Carcinoma-associated Antigen Defined by Monoclonal Antibody D612

Philip D. Fernsten, F. James Primus, John W. Greiner, Jean F. Simpson, and Jeffrey Schlom
Cancer Res 1991 51: 926-934. [Abstract] [PDF]  

Phase I Clinical Investigation of Benzisoquinolinedione (Amonafide) in Adults with Refractory or Relapsed Acute Leukemia

Susan O'Brien, John A. Benvenuto, Elihu Estey, Miloslav Beran, Tyrone B. Felder, and Michael Keating
Cancer Res 1991 51: 935-938. [Abstract] [PDF]  

Complementary DNA Encoding Human Colon Cancer Manganese Superoxide Dismutase and the Expression of Its Gene in Human Cells

Daret K. St. Clair and John C. Holland
Cancer Res 1991 51: 939-943. [Abstract] [PDF]  

Follow-up Study of HER-2/neu Amplification in Primary Breast Cancer

Gary M. Clark and William L. McGuire
Cancer Res 1991 51: 944-948. [Abstract] [PDF]  

Allelic Loss at Chromosome 3p Characterizes Clear Cell Phenotype of Renal Cell Carcinoma

Osamu Ogawa, Yoshiyuki Kakehi, Katsuhiko Ogawa, Masahiro Koshiba, Taketoshi Sugiyama, and Osamu Yoshida
Cancer Res 1991 51: 949-953. [Abstract] [PDF]  

Cytogenetic Analysis of 33 Basal Cell Carcinomas

Fredrik Mertens, Sverre Heim, Nils Mandahl, Bertil Johansson, Ove Mertens, Bertil Persson, Lars Salemark, Johan Wennerberg, Nils Jonsson, and Felix Mitelman
Cancer Res 1991 51: 954-957. [Abstract] [PDF]  

Carcinogen-induced Lymphomagenesis in pim-1 Transgenic Mice: Dose Dependence and Involvement of myc and ras

Marco Breuer, Ellen Wientjens, Sjef Verbeek, Robert Slebos, and Anton Berns
Cancer Res 1991 51: 958-963. [Abstract] [PDF]  

Peripheral Blood and Bone Marrow Immunophenotypic and Functional Modifications Induced in Acute Leukemia Patients Treated with Interleukin 2: Evidence of in Vivo Lymphokine Activated Killer Cell Generation

Robert Foa, Anna Guarini, Anna Gillio Tos, Silvia Cardona, Maria Teresa Fierro, Giovanna Meloni, Silvia Tosti, Franco Mandelli, and Felice Gavosto
Cancer Res 1991 51: 964-968. [Abstract] [PDF]  

An Unexpected Biotransformation Pathway for Tetrachloro-(d,l-trans)-1,2-diaminocyclohexaneplatinum(IV) (Tetraplatin) in the L1210 Cell Line

Stephen G. Chaney, Gregory R. Gibbons, Steven D. Wyrick, and Paula Podhasky
Cancer Res 1991 51: 969-973. [Abstract] [PDF]  

Induction of Heme Oxygenase: A General Response to Oxidant Stress in Cultured Mammalian Cells

Lee Ann Applegate, Patrick Luscher, and Rex M. Tyrrell
Cancer Res 1991 51: 974-978. [Abstract] [PDF]  

Development of Skin Tumors in Hairless Mice after Discontinuation of Ultraviolet Irradiation

Frank R. de Gruijl and Jan C. van der Leun
Cancer Res 1991 51: 979-984. [Abstract] [PDF]  

Hypomethylation and Reactivation of the Asparagine Synthetase Gene Induced by L-Asparaginase and Ethyl Methanesulfonate

Katharine S. Worton, Robert S. Kerbel, and Irene L. Andrulis
Cancer Res 1991 51: 985-989. [Abstract] [PDF]  

Scintigraphic Detection of Overexpressed c-erbB-2 Protooncogene Products by a Class-switched Murine Anti-c-erbB-2 Protein Monoclonal Antibody

Tsuneo Saga, Keigo Endo, Tetsu Akiyama, Harumi Sakahara, Mitsuru Koizumi, Yuji Watanabe, Toshiharu Nakai, Makoto Hosono, Tadashi Yamamoto, Kumao Toyoshima, and Junji Konishi
Cancer Res 1991 51: 990-994. [Abstract] [PDF]  

Development and Characterization of a Melphalan-resistant Human Multiple Myeloma Cell Line

William T. Bellamy, William S. Dalton, Mary C. Gleason, Thomas M. Grogan, and Jeffrey M. Trent
Cancer Res 1991 51: 995-1002. [Abstract] [PDF]  

Effect of Interclonal Heterogeneity on the Progressive, Confluence-mediated Acquisition of the Focus-forming Phenotype in NIH-3T3 Populations

Ralph Grundel and Harry Rubin
Cancer Res 1991 51: 1003-1013. [Abstract] [PDF]  

Detection of Human Papillomavirus DNA in Anal Intraepithelial Neoplasia and Anal Cancer

Joel M. Palefsky, Elizabeth A. Holly, John Gonzales, Jennifer Berline, David K. Ahn, and John S. Greenspan
Cancer Res 1991 51: 1014-1019. [Abstract] [PDF]  

Frequent Somatic Imbalance of Marker Alleles for Chromosome 1 in Human Primary Breast Carcinoma

Peter Devilee, Margreethe van Vliet, Alfons Bardoel, Tim Kievits, Nel Kuipers-Dijkshoorn, Peter L. Pearson, and Cees J. Cornelisse
Cancer Res 1991 51: 1020-1025. [Abstract] [PDF]  

Relationship of Pancreatic Cancer Apomucin to Mammary and Intestinal Apomucins

James C. Byrd, Jenny J. L. Ho, Derek T. A. Lamport, Samuel B. Ho, Bader Siddiki, Jian Huang, Pei-Sha Yan, and Young S. Kim
Cancer Res 1991 51: 1026-1033. [Abstract] [PDF]  

Evaluation of Immunoreactivity for erbB-2 Protein as a Marker of Poor Short Term Prognosis in Gastric Cancer

Yutaka Yonemura, Itasu Ninomiya, Akio Yamaguchi, Sachio Fushida, Hironobu Kimura, Shigekazu Ohoyama, Ituo Miyazaki, Yoshio Endou, Motohiro Tanaka, and Takuma Sasaki
Cancer Res 1991 51: 1034-1038. [Abstract] [PDF]  

Effects of Amiloride Treatment on U-118 MG and U-251 MG Human Glioma and HT-29 Human Colon Carcinoma Cells

Erika Szolgay-Daniel, Jörgen Carlsson, Karl Zierold, Georg Holtermann, Evelyne Dufau, and Helmut Acker
Cancer Res 1991 51: 1039-1044. [Abstract] [PDF]  

Promoter Independence as a Feature of Most Skin Papillomas in SENCAR Mice

C. Marcelo Aldaz, Claudio J. Conti, Aaron Chen, Albert Bianchi, S. Beth Walker, and John DiGiovanni
Cancer Res 1991 51: 1045-1050. [Abstract] [PDF]  

Announcements

Cancer Res 1991 51: 1055-1056. [PDF]  

Advances in Brief:

Expression of cripto, a Novel Gene of the Epidermal Growth Factor Gene Family, Leads to in Vitro Transformation of a Normal Mouse Mammary Epithelial Cell Line

Fortunato Ciardiello, Rosanna Dono, Nancy Kim, Maria Graziella Persico, and David S. Salomon
Cancer Res 1991 51: 1051-1054. [Abstract] [PDF]  

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