Advances in Brief:

Wavelength Specific Patterns of p53 Induction in Human Skin following Exposure to UV Radiation

Christine Campbell, Anthony G. Quinn, Brian Angus, Peter M. Farr, and Jonathan L. Rees
Cancer Res 1993 53: 2697-2699. [Abstract] [PDF]  

Enhancement of Heme Oxygenase Expression and Activity in A431 Squamous Carcinoma Multicellular Tumor Spheroids

Brian J. Murphy, Keith R. Laderoute, Hendrik J. Vreman, Tandora D. Grant, Navdeep S. Gill, David K. Stevenson, and Robert M. Sutherland
Cancer Res 1993 53: 2700-2703. [Abstract] [PDF]  

Enhanced Expression of the Type II Transforming Growth Factor ß Receptor in Human Pancreatic Cancer Cells without Alteration of Type III Receptor Expression

Helmut Friess, Yoichiro Yamanaka, Markus Büchler, Hans G. Beger, Michael S. Kobrin, Rae Lynn Baldwin, and Murray Korc
Cancer Res 1993 53: 2704-2707. [Abstract] [PDF]  

Increased Resistance to Oncostatin M-induced Growth Inhibition of Human Melanoma Cell Lines Derived from Advanced-Stage Lesions

Chao Lu, Janusz W. Rak, Hiroaki Kobayashi, and Robert S. Kerbel
Cancer Res 1993 53: 2708-2711. [Abstract] [PDF]  

Analysis of WT1 in Granulosa Cell and Other Sex Cord-Stromal Tumors

Max J. Coppes, Ying Ye, Raymond Rackley, Xiao-lan Zhao, Gerrit Jan Liefers, Graham Casey, and Bryan R. G. Williams
Cancer Res 1993 53: 2712-2714. [Abstract] [PDF]  

DNA Hypermethylation Is Associated with 17p Allelic Loss in Neural Tumors

Michele Makos, Barry D. Nelkin, Victoria R. Chazin, Webster K. Cavenee, Garrett M. Brodeur, and Stephen B. Baylin
Cancer Res 1993 53: 2715-2718. [Abstract] [PDF]  

Regional DNA Hypermethylation at D17S5 Precedes 17p Structural Changes in the Progression of Renal Tumors

Michele Makos, Barry D. Nelkin, Robert E. Reiter, James R. Gnarra, James Brooks, William Isaacs, Marston Linehan, and Stephen B. Baylin
Cancer Res 1993 53: 2719-2722. [Abstract] [PDF]  

Frequent Loss of Expression and Loss of Heterozygosity of the Putative Tumor Suppressor Gene DCC in Prostatic Carcinomas

Xiang Gao, Kenneth V. Honn, David Grignon, Wael Sakr, and Yong Q. Chen
Cancer Res 1993 53: 2723-2727. [Abstract] [PDF]  

Association between Wild Type and Mutant APC Gene Products

Li-Kuo Su, Karen A. Johnson, Kelly J. Smith, David E. Hill, Bert Vogelstein, and Kenneth W. Kinzler
Cancer Res 1993 53: 2728-2731. [Abstract] [PDF]  

Cloning of bcl-6, the Locus Involved in Chromosome Translocations Affecting Band 3q27 in B-Cell Lymphoma

Bihui H. Ye, P. H. Rao, R. S. K. Chaganti, and Riccardo Dalla-Favera
Cancer Res 1993 53: 2732-2735. [Abstract] [PDF]  

Amplification and Overexpression of the MDM2 Gene in a Subset of Human Malignant Gliomas without p53 Mutations

Guido Reifenberger, Lu Liu, Koichi Ichimura, Esther E. Schmidt, and V. Peter Collins
Cancer Res 1993 53: 2736-2739. [Abstract] [PDF]  

Biochemistry and Biophysics:

Sensitivity of Human Cells to Mild Hyperthermia

Elwood P. Armour, Donna McEachern, Zhenhua Wang, Peter M. Corry, and Alvaro Martinez
Cancer Res 1993 53: 2740-2744. [Abstract] [PDF]  

Carcinogenesis:

Effects of Caloric Restriction and Dietary Fat on Epithelial Cell Proliferation in Rat Colon

Gideon Steinbach, Siva P. Kumar, Bandaru S. Reddy, Martin Lipkin, and Peter R. Holt
Cancer Res 1993 53: 2745-2749. [Abstract] [PDF]  

The Growth Hormone: Insulin-like Growth Factor 1 Axis Is a Mediator of Diet Restriction-induced Inhibition of Mononuclear Cell Leukemia in Fischer Rats

Stephen D. Hursting, Boyd R. Switzer, John E. French, and Frank W. Kari
Cancer Res 1993 53: 2750-2757. [Abstract] [PDF]  

A Study of Tobacco Carcinogenesis: Effect of the Fat Content of the Diet on the Carcinogenic Activity of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in F344 Rats

Dietrich Hoffmann, Abraham Rivenson, Rakesh Abbi, and Ernst L. Wynder
Cancer Res 1993 53: 2758-2761. [Abstract] [PDF]  

Increased Protein Kinase C Expression in Human Colonic Caco-2 Cells after Insertion of Human Ha-ras or Polyoma Virus Middle T Oncogenes

Sophie Delage, Eric Chastre, Sylvie Empereur, Denise Wicek, Danielle Veissiére, Jacqueline Capeau, Christian Gespach, and Gisèle Cherqui
Cancer Res 1993 53: 2762-2770. [Abstract] [PDF]  

Fluorescence Postlabeling Assay of DNA Damage Induced by N-Methyl-N-nitrosourea

Rama Jain and Minoti Sharma
Cancer Res 1993 53: 2771-2774. [Abstract] [PDF]  

Chemoprevention of Diethylnitrosamine-induced Hepatocarcinogenesis by a Simple Phenolic Acid Protocatechuic Acid in Rats

Takuji Tanaka, Toshihiro Kojima, Toshihiko Kawamori, Naoki Yoshimi, and Hideki Mori
Cancer Res 1993 53: 2775-2779. [Abstract] [PDF]  

Pyridyloxobutyl DNA Adducts Inhibit the Repair of O⁶-Methylguanine

Lisa A. Peterson, Xiao-Keng Liu, and Stephen S. Hecht
Cancer Res 1993 53: 2780-2785. [Abstract] [PDF]  

Reduction in Formation and Growth of 1,2-Dimethylhydrazine-induced Aberrant Crypt Foci in Rat Colon by Docosahexanoic Acid

Mami Takahashi, Toshinari Minamoto, Naoyuki Yamashita, Kazunaga Yazawa, Takashi Sugimura, and Hiroyasu Esumi
Cancer Res 1993 53: 2786-2789. [Abstract] [PDF]  

The Significance of DNA Damage, Its Repair and Cell Proliferation during Carcinogen Treatment in the Initiation of Pancreatic Cancer in the Hamster Model

Demetrius M. Kokkinakis and Vadrevu Subbarao
Cancer Res 1993 53: 2790-2795. [Abstract] [PDF]  

Clinical Investigations:

Initial Clinical (Phase I) Trial of TLC D-99 (Doxorubicin Encapsulated in Liposomes)

J. W. Cowens, P. J. Creaven, W. R. Greco, D. E. Brenner, Y. Tung, M. Ostro, F. Pilkiewicz, R. Ginsberg, and N. Petrelli
Cancer Res 1993 53: 2796-2802. [Abstract] [PDF]  

Clinical Evaluation of M43: A Novel Cancer-associated Mucin Epitope

Richard Goodgame, Catarina Kiefe, Esme Rose, Fred Sutton, Joseph Brown, and Elliot Alpert
Cancer Res 1993 53: 2803-2809. [Abstract] [PDF]  

Experimental Therapeutics:

In Vivo Administration of the Anticancer Agent Bryostatin 1 Activates Platelets and Neutrophils and Modulates Protein Kinase C Activity

Roger L. Berkow, Larry Schlabach, Robert Dodson, William H. Benjamin, Jr., George R. Pettit, Pradip Rustagi, and Andrew S. Kraft
Cancer Res 1993 53: 2810-2815. [Abstract] [PDF]  

Relationship between Circadian-dependent Toxicity of 5-Fluorodeoxyuridine and Circadian Rhythms of Pyrimidine Enzymes: Possible Relevance to Fluoropyrimidine Chemotherapy

Ruiwen Zhang, Zhihong Lu, Tiepu Liu, Seng-jaw Soong, and Robert B. Diasio
Cancer Res 1993 53: 2816-2822. [Abstract] [PDF]  

Therapeutic Efficacy of the Topoisomerase I Inhibitor 7-Ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against Human Tumor Xenografts: Lack of Cross-Resistance in Vivo in Tumors with Acquired Resistance to the Topoisomerase I Inhibitor 9-Dimethylaminomethyl-10-hydroxycamptothecin

Peter J. Houghton, Pamela J. Cheshire, James C. Hallman, Marie C. Bissery, Anne Mathieu-Boué, and Janet A. Houghton
Cancer Res 1993 53: 2823-2829. [Abstract] [PDF]  

Immunology:

Association of High Molecular Weight Melanoma-associated Antigen Expression in Primary Acral Lentiginous Melanoma Lesions with Poor Prognosis

Toshiro Kageshita, Norikazu Kuriya, Tomomichi Ono, Takashi Horikoshi, Makoto Takahashi, George Y. Wong, and Soldano Ferrone
Cancer Res 1993 53: 2830-2833. [Abstract] [PDF]  

Preclinical Evaluation of ¹¹¹In-labeled B3 Monoclonal Antibody: Biodistribution and Imaging Studies in Nude Mice Bearing Human Epidermoid Carcinoma Xenografts

Luigi Camera, Seigo Kinuya, Lee H. Pai, Kayhan Garmestani, Martin W. Brechbiel, Otto A. Gansow, Chang H. Paik, Ira Pastan, and Jorge A. Carrasquillo
Cancer Res 1993 53: 2834-2839. [Abstract] [PDF]  

Monoclonal Antibody SEN7 Recognizes a New Epitope on the Neural Cell Adhesion Molecule Present on Small Cell Lung Cancer but Not on Lymphocytes

Robert Waibel, Meinrad Mannhart, Carl J. O'Hara, Cathy Brocklehurst, Uwe Zangemeister-Wittke, Thomas Schenker, Hans-Peter Lehmann, Erich Weber, and Rolf A. Stahel
Cancer Res 1993 53: 2840-2845. [Abstract] [PDF]  

Molecular Biology and Genetics:

p53 Alterations in Non-Small Cell Lung Cancers Correlate with Metastatic Involvement of Hilar and Mediastinal Lymph Nodes

Antonio Marchetti, Fiamma Buttitta, Giorgio Merlo, Francesca Diella, Silvia Pellegrini, Stefano Pepe, Paolo Macchiarini, Antonio Chella, C. Alberto Angeletti, Robert Callahan, Maria Bistocchi, and Francesco Squartini
Cancer Res 1993 53: 2846-2851. [Abstract] [PDF]  

Autocrine Regulation of Prostate-specific Antigen Gene Expression in a Human Prostatic Cancer (LNCaP) Subline

Jer-Tsong Hsieh, Hsi-Chin Wu, Martin E. Gleave, Andrew C. von Eschenbach, and Leland W. K. Chung
Cancer Res 1993 53: 2852-2857. [Abstract] [PDF]  

Normal Human Mesothelial Cells and Mesothelioma Cell Lines Express Insulin-like Growth Factor I and Associated Molecules

Theodore C. Lee, Yihong Zhang, Christopher Aston, Raymond Hintz, Jaishree Jagirdar, Mary Ann Perle, Michael Burt, and William N. Rom
Cancer Res 1993 53: 2858-2864. [Abstract] [PDF]  

Mutagenicity and Mutational Spectrum of N-Methyl-N'-nitro-N-nitrosoguanidine in the hprt Gene in G₁-S and Late S Phase of Diploid Human Fibroblasts

Jia-Ling Yang, Jin-Guo Lin, Meng-Chuen Hu, and Cheng-Wen Wu
Cancer Res 1993 53: 2865-2873. [Abstract] [PDF]  

Increased Polysomies of Chromosomes 7 and 17 during Head and Neck Multistage Tumorigenesis

Narin Voravud, Dong M. Shin, Jae Y. Ro, Jin S. Lee, Waun Ki Hong, and Walter N. Hittelman
Cancer Res 1993 53: 2874-2883. [Abstract] [PDF]  

Tumor Progression in Hepatocellular Carcinoma May Be Mediated by p53 Mutation

Shinji Tanaka, Yasushi Toh, Eisuke Adachi, Takashi Matsumata, Ryoichi Mori, and Keizo Sugimachi
Cancer Res 1993 53: 2884-2887. [Abstract] [PDF]  

Isolation of Kidney Complementary DNAs Down-expressed in Wilms' Tumor by a Subtractive Hybridization Approach

Estelle Austruy, Martine Cohen-Salmon, Corinne Antignac, Christophe Béroud, Isabelle Henry, Nguyen Van Cong, Laurence Brugières, Claudine Junien, and Cécile Jeanpierre
Cancer Res 1993 53: 2888-2894. [Abstract] [PDF]  

Codons 12 and 13 of H-ras Protooncogene Interrupt the Progression of DNA Synthesis Catalyzed by DNA Polymerase

Jean-Sébastien Hoffmann, Michael Fry, Jiuping Ji, Kandace J. Williams, and Lawrence A. Loeb
Cancer Res 1993 53: 2895-2900. [Abstract] [PDF]  

Tumor Biology:

Correlation between Mannose-6-phosphate/IGFII Receptor and Cathepsin D RNA Levels by in Situ Hybridization in Benign and Malignant Mammary Tumors

Yong Zhao, Chantal Escot, Thierry Maudelonde, Carole Puech, Philippe Rouanet, and Henri Rochefort
Cancer Res 1993 53: 2901-2905. [Abstract] [PDF]  

Isoglobotetraosylceramide Is a Marker for Highly Metastatic Cells in Rat Mammary Adenocarcinomas

Svein A. Carlsen, Yushuang Xie, Dennis M. Whitfield, Henrianna Pang, and Jiri J. Krepinsky
Cancer Res 1993 53: 2906-2911. [Abstract] [PDF]  

Vascular Permeability Factor (Vascular Endothelial Growth Factor) in Guinea Pig and Human Tumor and Inflammatory Effusions

Kiang-Teck Yeo, Helen H. Wang, Janice A. Nagy, Tracy M. Sioussat, Steven R. Ledbetter, Arlene J. Hoogewerf, Ying Zhou, Elizabeth M. Masse, Donald R. Senger, Harold F. Dvorak, and Tet-Kin Yeo
Cancer Res 1993 53: 2912-2918. [Abstract] [PDF]  

Expression of the Gastrin Gene in the Normal Human Colon and Colorectal Adenocarcinoma

Gene G. Finley, Raymond A. Koski, Mona F. Melhem, James M. Pipas, and Arnold I. Meisler
Cancer Res 1993 53: 2919-2926. [Abstract] [PDF]  

Successive Activation of the Platelet-derived Growth Factor ß Receptor and Platelet-derived Growth Factor B Genes Correlates with the Genesis of Human Choriocarcinoma

Lars Holmgren, Folke Flam, Erik Larsson, and Rolf Ohlsson
Cancer Res 1993 53: 2927-2931. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 2932-2933. [PDF]  

Recent Death

Cancer Res 1993 53: 2933 [PDF]  

Calendar of Events

Cancer Res 1993 53: 2933-2934. [PDF]  

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