Advances in Brief:

Increased Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor and Transforming Growth Factor ß1 Levels during Monoterpene-induced Regression of Mammary Tumors

Randy L. Jirtle, Jill D. Haag, Eric A. Ariazi, and Michael N. Gould
Cancer Res 1993 53: 3849-3852. [Abstract] [PDF]  

Heterogeneity in MLL/AF-4 Fusion Messenger RNA Detected by the Polymerase Chain Reaction in t(4;11) Acute Leukemia

Joanne M. Hilden, Chien-Shing Chen, Roderick Moore, Joy Frestedt, and John H. Kersey
Cancer Res 1993 53: 3853-3856. [Abstract] [PDF]  

The Effect of Stem Cell Factor on Irradiated Human Bone Marrow

Bryan R. Leigh, Steven L. Hancock, and Susan J. Knox
Cancer Res 1993 53: 3857-3859. [Abstract] [PDF]  

Use of Tissue-specific Expression of the Herpes Simplex Virus Thymidine Kinase Gene to Inhibit Growth of Established Murine Melanomas following Direct Intratumoral Injection of DNA

Richard G. Vile and Ian R. Hart
Cancer Res 1993 53: 3860-3864. [Abstract] [PDF]  

Association of Putative Origins of Replication with the Nuclear Matrix in Normal Human Fibroblasts

Bruna P. Brylawski, Gregory J. Tsongalis, Marila Cordeiro-Stone, W. Todd May, Laurey D. Comeau, and David G. Kaufman
Cancer Res 1993 53: 3865-3868. [Abstract] [PDF]  

Homozygous Deletion and Frequent Allelic Loss of Chromosome 8p22 Loci in Human Prostate Cancer

G. Steven Bova, Bob S. Carter, Marion J. G. Bussemakers, Mitsuru Emi, Yoshiyuki Fujiwara, Natasha Kyprianou, Stephen C. Jacobs, John C. Robinson, Jonathan I. Epstein, Patrick C. Walsh, and William B. Isaacs
Cancer Res 1993 53: 3869-3873. [Abstract] [PDF]  

Transplacental Carcinogenicity of Cisplatin: Initiation of Skin Tumors and Induction of Other Preneoplastic and Neoplastic Lesions in SENCAR Mice

Bhalchandra A. Diwan, Lucy M. Anderson, Sabine Rehm, and Jerry M. Rice
Cancer Res 1993 53: 3874-3876. [Abstract] [PDF]  

Alternatively Spliced Glucocorticoid Receptor Messenger RNAs in Glucocorticoid-resistant Human Multiple Myeloma Cells

Pamela A. Moalli, Shafali Pillay, Nancy L. Krett, and Steven T. Rosen
Cancer Res 1993 53: 3877-3879. [Abstract] [PDF]  

Carcinogenesis:

Radiation-induced Transforming Growth Factor ß and Subsequent Extracellular Matrix Reorganization in Murine Mammary Gland

M. H. Barcellos-Hoff
Cancer Res 1993 53: 3880-3886. [Abstract] [PDF]  

Resistance to Aflatoxin B₁ Is Associated with the Expression of a Novel Aldo-Keto Reductase Which Has Catalytic Activity towards a Cytotoxic Aldehyde-containing Metabolite of the Toxin

John D. Hayes, David J. Judah, and Gordon E. Neal
Cancer Res 1993 53: 3887-3894. [Abstract] [PDF]  

Repair of O⁶-Methylguanine and O⁴-Methylthymidine in F344 Rat Liver following Treatment with 1,2-Dimethylhydrazine and O⁶-Benzylguanine

Susan M. O'Toole, Anthony E. Pegg, and James A. Swenberg
Cancer Res 1993 53: 3895-3898. [Abstract] [PDF]  

N-Acetylglucosaminyltransferase III and V Messenger RNA Levels in LEC Rats during Hepatocarcinogenesis

Eiji Miyoshi, Atsushi Nishikawa, Yoshito Ihara, Jianguo Gu, Toshihiro Sugiyama, Norio Hayashi, Hideyuki Fusamoto, Takenobu Kamada, and Naoyuki Taniguchi
Cancer Res 1993 53: 3899-3902. [Abstract] [PDF]  

Chemopreventive Effects of Dietary D,L--Difluoromethylornithine, an Ornithine Decarboxylase Inhibitor, on Initiation and Postinitiation Stages of Diethylnitrosamine-induced Rat Hepatocarcinogenesis

Toshihiro Kojima, Takuji Tanaka, Toshihiko Kawamori, Akira Hara, and Hideki Mori
Cancer Res 1993 53: 3903-3907. [Abstract] [PDF]  

Chemoprevention of Colon Carcinogenesis by the Natural Product of a Simple Phenolic Compound Protocatechuic Acid: Suppressing Effects on Tumor Development and Biomarkers Expression of Colon Tumorigenesis

Takuji Tanaka, Toshihiro Kojima, Masumi Suzui, and Hideki Mori
Cancer Res 1993 53: 3908-3913. [Abstract] [PDF]  

Inhibitory Effect of Bifidobacterium longum on Colon, Mammary, and Liver Carcinogenesis Induced by 2-Amino-3-methylimidazo[4,5-f]quinoline, a Food Mutagen

Bandaru S. Reddy and Abraham Rivenson
Cancer Res 1993 53: 3914-3918. [Abstract] [PDF]  

Two-Year Carcinogenicity Study of Tamoxifen in Alderley Park Wistar-derived Rats

Peter Greaves, Ranjit Goonetilleke, Gary Nunn, John Topham, and Terry Orton
Cancer Res 1993 53: 3919-3924. [Abstract] [PDF]  

Stimulation of Growth of Azaserine-induced Putative Preneoplastic Lesions in Rat Pancreas Is Mediated Specifically by Way of Cholecystokinin-A Receptors

Stephen P. Povoski, Weigong Zhou, Daniel S. Longnecker, Bill D. Roebuck, and Richard H. Bell, Jr.
Cancer Res 1993 53: 3925-3929. [Abstract] [PDF]  

Clinical Investigations:

Phase I Trial of a 90-Minute Infusion of the Fusion Toxin DAB₄₈₆IL-2 in Hematological Cancers

C. F. LeMaistre, Fiona E. Craig, Carole Meneghetti, Becky McMullin, Karen Parker, James Reuben, David H. Boldt, Michael Rosenblum, and Thasia Woodworth
Cancer Res 1993 53: 3930-3934. [Abstract] [PDF]  

Endocrinology:

Selective Biological Response by Target Organs (Intestine, Kidney, and Bone) to 1,25-Dihydroxyvitamin D₃ and Two Analogues

Anthony W. Norman, Igor N. Sergeev, June E. Bishop, and William H. Okamura
Cancer Res 1993 53: 3935-3942. [Abstract] [PDF]  

Control of HLA-DR Antigen Expression by -Interferon: Separate Signal Transduction Mechanisms in Malignant and Nonmalignant Human Thyroid Cells

Nitza Lahat, Esther Sobel, and Zaki Kraiem
Cancer Res 1993 53: 3943-3947. [Abstract] [PDF]  

Experimental Therapeutics:

Interaction of a Polyamine Analogue, 1,19-bis-(Ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4), with DNA and Effect on Growth, Survival, and Polyamine Levels in Seven Human Brain Tumor Cell Lines

Hirak S. Basu, Malgorzata Pellarin, Burt G. Feuerstein, Akira Shirahata, Keijiro Samejima, Dennis F. Deen, and Laurence J. Marton
Cancer Res 1993 53: 3948-3955. [Abstract] [PDF]  

Site-specific Prodrug Activation by Antibody-ß-Lactamase Conjugates: Regression and Long-Term Growth Inhibition of Human Colon Carcinoma Xenograft Models

Damon L. Meyer, Louis N. Jungheim, Kevin L. Law, Stephen D. Mikolajczyk, Timothy A. Shepherd, Daniel G. Mackensen, Stephen L. Briggs, and James J. Starling
Cancer Res 1993 53: 3956-3963. [Abstract] [PDF]  

Arrest of Human Lung Tumor Xenograft Growth in Severe Combined Immunodeficient Mice Using Doxorubicin Encapsulated in Sterically Stabilized Liposomes

Scott S. Williams, Thomas R. Alosco, Eric Mayhew, Danilo D. Lasic, Frank J. Martin, and Richard B. Bankert
Cancer Res 1993 53: 3964-3967. [Abstract] [PDF]  

Neuroblastoma Sensitivity to Growth Inhibition by Deferrioxamine: Evidence for a Block in G₁ Phase of the Cell Cycle

Chaya Brodie, Gamini Siriwardana, Joseph Lucas, Rhoda Schleicher, Nao Terada, Agota Szepesi, Erwin Gelfand, and Paul Seligman
Cancer Res 1993 53: 3968-3975. [Abstract] [PDF]  

Specific Proteolytic Cleavage of Poly(ADP-ribose) Polymerase: An Early Marker of Chemotherapy-induced Apoptosis

Scott H. Kaufmann, Serge Desnoyers, Yvonne Ottaviano, Nancy E. Davidson, and Guy G. Poirier
Cancer Res 1993 53: 3976-3985. [Abstract] [PDF]  

In Vitro and in Vivo Effect of Doxorubicin Combined with Liposome-encapsulated Muramyl Tripeptide on Canine Monocyte Activation

Fushun Shi, E. Gregory MacEwen, and Ilene D. Kurzman
Cancer Res 1993 53: 3986-3991. [Abstract] [PDF]  

Unusual Oxygen Concentration Dependence of Toxicity of SR-4233, a Hypoxic Cell Toxin

C. J. Koch
Cancer Res 1993 53: 3992-3997. [Abstract] [PDF]  

Amphibolic Drug Combinations: The Design of Selective Antimetabolite Protocols Based upon the Kinetic Properties of Multienzyme Systems

Robert C. Jackson
Cancer Res 1993 53: 3998-4003. [Abstract] [PDF]  

Inhibition by Oxonic Acid of Gastrointestinal Toxicity of 5-Fluorouracil without Loss of Its Antitumor Activity in Rats

Tetsuhiko Shirasaka, Yuji Shimamoto, and Masakazu Fukushima
Cancer Res 1993 53: 4004-4009. [Abstract] [PDF]  

Immunology:

Interleukin-1ß Induces Interleukin-1 Receptor Antagonist and Tumor Necrosis Factor Binding Protein in Humans

Mario J. Bargetzi, Mikael Lantz, Christopher G. Smith, Frank M. Torti, Inge Olsson, Stephen P. Eisenberg, and H. Fletcher Starnes, Jr.
Cancer Res 1993 53: 4010-4013. [Abstract] [PDF]  

Killing of Skin-derived Tumor Cells by Mouse Dendritic Epidermal T-Cells

Marek J. Kaminski, Ponciano D. Cruz, Jr., Paul R. Bergstresser, and Akira Takashima
Cancer Res 1993 53: 4014-4019. [Abstract] [PDF]  

Tumor-specific Lysis of Human Renal Cell Carcinomas by Tumor-infiltrating Lymphocytes: Modulation of Recognition through Retroviral Transduction of TumorCells with Interleukin 2 Complementary DNA and Exogenous Interferon Treatment

Dolores J. Schendel and Bernd Gansbacher
Cancer Res 1993 53: 4020-4025. [Abstract] [PDF]  

Highly Specific in Vivo Tumor Targeting by Monovalent and Divalent Forms of 741F8 Anti-c-erbB-2 Single-Chain Fv

Gregory P. Adams, John E. McCartney, Mei-Sheng Tai, Hermann Oppermann, James S. Huston, Walter F. Stafford, III, Michael A. Bookman, Irwin Fand, L. L. Houston, and Louis M. Weiner
Cancer Res 1993 53: 4026-4034. [Abstract] [PDF]  

Molecular Biology and Genetics:

Genotypic Characterization of Prostatic Carcinomas: A Combined Cytogenetic, Flow Cytometry, and in Situ DNA Hybridization Study

Thomas Breitkreuz, Konstantinos Romanakis, Steffi Lutz, Gerhard Seitz, Helmut Bonkhoff, Gerhard Unteregger, Thomas Zwergel, Klaus Dieter Zang, and Bernd Wullich
Cancer Res 1993 53: 4035-4040. [Abstract] [PDF]  

Transforming Growth Factor-ß1 Induces Transforming Growth Factor- Promoter Activity and Transforming Growth Factor- Secretion in the Human Colon Adenocarcinoma Cell Line FET

Mark J. Lynch, Lenore Pelosi, Joan M. Carboni, June Merwin, Kevin Coleman, Richard R. C. Wang, Pin-Fang M. Lin, Diane L. Henry, and Michael G. Brattain
Cancer Res 1993 53: 4041-4047. [Abstract] [PDF]  

Gastric and Hepatocellular Carcinomas Do Not Overexpress the Same Ribosomal Protein Messenger RNAs as Colonic Carcinoma

Graham F. Barnard, Raymond J. Staniunas, Masaki Mori, Mark Puder, Milburn J. Jessup, Glenn D. Steele, Jr., and Lan Bo Chen
Cancer Res 1993 53: 4048-4052. [Abstract] [PDF]  

Mutation of the p53 Gene in Neuroblastoma and Its Relationship with N-myc Amplification

Jun Imamura, Claus R. Bartram, Frank Berthold, Dieter Harms, Haruhiko Nakamura, and H. Phillip Koeffler
Cancer Res 1993 53: 4053-4058. [Abstract] [PDF]  

Cloning and Expression of Mutant Glucocorticoid Receptors from Glucocorticoid-sensitive and -resistant Human Leukemic Cells

Joan H. Powers, Andrew G. Hillmann, Delia C. Tang, and Jeffrey M. Harmon
Cancer Res 1993 53: 4059-4065. [Abstract] [PDF]  

Role of Chromosome 9 in Human Bladder Cancer

Noriomi Miyao, Yvonne C. Tsai, Seth P. Lerner, Aria F. Olumi, Charles H. Spruck, III, Mirella Gonzalez-Zulueta, Peter W. Nichols, Donald G. Skinner, and Peter A. Jones
Cancer Res 1993 53: 4066-4070. [Abstract] [PDF]  

Tumor Biology:

Clonal Analysis of Fibroadenoma and Phyllodes Tumor of the Breast

Shinzaburo Noguchi, Kazuyoshi Motomura, Hideo Inaji, Shingi Imaoka, and Hiroki Koyama
Cancer Res 1993 53: 4071-4074. [Abstract] [PDF]  

Differential Growth Factor Production, Secretion, and Response by High and Low Metastatic Variants of B16BL6 Melanoma

Vincent D. Blanckaert, Margaret E. Schelling, Catherine A. Elstad, and Gary G. Meadows
Cancer Res 1993 53: 4075-4081. [Abstract] [PDF]  

Altered Glycosylation of the MUC-1 Protein Core Contributes to the Colon Carcinoma-associated Increase of Mucin-bound Sialyl-Lewis^x Expression

Christoph Hanski, Kristin Drechsler, Franz-Georg Hanisch, John Sheehan, Monika Manske, Dieter Ogorek, Enno Klussmann, Marie-Luise Hanski, Monika Blank, Pei-Xiang Xing, Ian F. C. McKenzie, Peter L. Devine, and Ernst-Otto Riecken
Cancer Res 1993 53: 4082-4088. [Abstract] [PDF]  

Cell Lines from grc Congenic Strains of Rats Having Different Susceptibilities to Chemical Carcinogens

Di Lu, Heinz W. Kunz, Mona F. Melhem, and Thomas J. Gill, III
Cancer Res 1993 53: 4089-4095. [Abstract] [PDF]  

Identification of a New Interferon--inducible Gene (p27) on Human Chromosome 14q32 and Its Expression in Breast Carcinoma

Ulla B. Rasmussen, Catherine Wolf, Marie-Geneviève Mattei, Marie-Pierre Chenard, Jean-Pierre Bellocq, Pierre Chambon, Marie-Christine Rio, and Paul Basset
Cancer Res 1993 53: 4096-4101. [Abstract] [PDF]  

Interleukin 1 Acts as an Autocrine Growth Stimulator for Human Gastric Carcinoma Cells

Reiko Ito, Yasuhiko Kitadai, Eikai Kyo, Hiroshi Yokozaki, Wataru Yasui, Uki Yamashita, Hiromasa Nikai, and Eiichi Tahara
Cancer Res 1993 53: 4102-4106. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: R. Peto et al., Effects on 4080 Rats of Chronic Ingestion of N-Nitrosodiethylamine or N-Nitrosodimethylamine: A Detailed Dose-Response Study. Cancer Res., 51: 6415–6451, 1991, and K. S. Crump et al., Fundamental Carcinogenic Processes and Their Implications for Low Dose Risk Assessment. Cancer Res., 36: 2973–2979, 1976.

Gerhard Stöhrer
Cancer Res 1993 53: 4107 [PDF]  

Correspondence re: R. Peto et al., Effects on 4080 Rats of Chronic Ingestion of N-Nitrosodiethylamine or N-Nitrosodimethylamine: A Detailed Dose-Response Study. Cancer Res., 51: 6415–6451, 1991, and K. S. Crump et al., Fundamental Carcinogenic Processes and Their Implications for Low Dose Risk Assessment. Cancer Res., 36: 2973–2979, 1976. — Reply

Richard Peto and Richard Gray
Cancer Res 1993 53: 4108 [PDF]  

Meeting Report:

Differentiation Therapy of Cancer: Laboratory and Clinical Investigations

Ernest C. Borden, Reuben Lotan, David Levens, Charles W. Young, and Samuel Waxman
Cancer Res 1993 53: 4109-4115. [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 4116-4118. [PDF]  

Recent Death

Cancer Res 1993 53: 4118 [PDF]  

Calendar of Events

Cancer Res 1993 53: 4118 [PDF]  

Erratum

Cancer Res 1993 53: 4119 [PDF]  

Erratum

Cancer Res 1993 53: 4119 [PDF]  

Erratum

Cancer Res 1993 53: 4119 [PDF]  

Employment Register of the American Association for Cancer Research

Cancer Res 1993 53: 4120-4126. [PDF]  

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