Advances in Brief:

The Small Heat Shock Protein hsp27 Is Correlated with Growth and Drug Resistance in Human Breast Cancer Cell Lines

Steffi Oesterreich, Chye-Ning Weng, Ming Qiu, Susan G. Hilsenbeck, C. Kent Osborne, and Suzanne A. W. Fuqua
Cancer Res 1993 53: 4443-4448. [Abstract] [PDF]  

Detection of the AML1/ETO Fusion Transcript in the t(8;21) Masked Translocation in Acute Myelogenous Leukemia

Fumio Maruyama, Peirong Yang, Sanford A. Stass, Ann Cork, Emil J Freireich, Ming-Sheng Lee, and Kun-Sang Chang
Cancer Res 1993 53: 4449-4451. [Abstract] [PDF]  

Dominant Negative Effect of a Germ-line Mutant p53: A Step Fostering Tumorigenesis

Shiv Srivastava, Shouwen Wang, Yue Ao Tong, Zheng-Mei Hao, and Esther H. Chang
Cancer Res 1993 53: 4452-4455. [Abstract] [PDF]  

Comparison of Loss of Heterozygosity Patterns in Invasive Low-Grade and High-Grade Epithelial Ovarian Carcinomas

Mark K. Dodson, Lynn C. Hartmann, William A. Cliby, Karen A. DeLacey, Gary L. Keeney, Steve R. Ritland, John Q. Su, Karl C. Podratz, and Robert B. Jenkins
Cancer Res 1993 53: 4456-4460. [Abstract] [PDF]  

Dietary Fenretinide, a Synthetic Retinoid, Decreases the Tumor Incidence and the Tumor Mass of ras+myc-induced Carcinomas in the Mouse Prostate Reconstitution Model System

K. Slawin, D. Kadmon, S. H. Park, P. T. Scardino, M. Anzano, M. B. Sporn, and T. C. Thompson
Cancer Res 1993 53: 4461-4465. [Abstract] [PDF]  

Induction of Protein-DNA Complexes in HeLa S3 Cells by KW-2149, a New Derivative of Mitomycin C

Noboru Fujii, Hitoshi Arai, Hiromitsu Saito, Masaji Kasai, and Hirofumi Nakano
Cancer Res 1993 53: 4466-4468. [Abstract] [PDF]  

Redox Modulation of p53 Conformation and Sequence-specific DNA Binding in Vitro

Pierre Hainaut and Jo Milner
Cancer Res 1993 53: 4469-4473. [Abstract] [PDF]  

Activation of Phospholipase D Participates in Signal Transduction Pathways Responsive to -Radiation

Matías A. Avila, Gabriel Otero, José Cansado, Anatoly Dritschilo, Juan A. Velasco, and Vicente Notario
Cancer Res 1993 53: 4474-4476. [Abstract] [PDF]  

The Incidence of p53 Mutations Increases with Progression of Head and Neck Cancer

Jay O. Boyle, John Hakim, Wayne Koch, Peter van der Riet, Ralph H. Hruban, R. Arturo Roa, Russell Correo, Yolanda J. Eby, J. Michael Ruppert, and David Sidransky
Cancer Res 1993 53: 4477-4480. [Abstract] [PDF]  

Human Immunodeficiency Virus Type 1 Tat Protein Protects Lymphoid, Epithelial, and Neuronal Cell Lines from Death by Apoptosis

Giorgio Zauli, Davide Gibellini, Daniela Milani, Meri Mazzoni, Paola Borgatti, Michele La Placa, and Silvano Capitani
Cancer Res 1993 53: 4481-4485. [Abstract] [PDF]  

Refinement of Regional Loss of Heterozygosity for Chromosome 11p15.5 in Human Breast Tumors

Robert Winqvist, Arto Mannermaa, Martti Alavaikko, Guillermo Blanco, Pentti J. Taskinen, Heikki Kiviniemi, Irene Newsham, and Webster Cavenee
Cancer Res 1993 53: 4486-4488. [Abstract] [PDF]  

Potential Topoisomerase II DNA-binding Sites at the Breakpoints of a t(9;11) Chromosome Translocation in Acute Myeloid Leukemia

M. Negrini, C. A. Felix, C. Martin, B. J. Lange, T. Nakamura, E. Canaani, and C. M. Croce
Cancer Res 1993 53: 4489-4492. [Abstract] [PDF]  

Regular Articles:

Secretion of Matrix Metalloproteinases and Their Inhibitors (Tissue Inhibitor of Metalloproteinases) by Human Prostate in Explant Cultures: Reduced Tissue Inhibitor of Metalloproteinase Secretion by Malignant Tissues

Balakrishna L. Lokeshwar, Marie G. Selzer, Norman L. Block, and Zeenat Gunja-Smith
Cancer Res 1993 53: 4493-4498. [Abstract] [PDF]  

Ability of Aberrant Crypt Foci Characteristics to Predict Colonic Tumor Incidence in Rats Fed Cholic Acid

Bernadene A. Magnuson, Ian Carr, and Ranjana P. Bird
Cancer Res 1993 53: 4499-4504. [Abstract] [PDF]  

Singlet Oxygen: A Primary Effector in the Ultraviolet A/Near-Visible Light Induction of the Human Heme Oxygenase Gene

Sharmila Basu-Modak and Rex M. Tyrrell
Cancer Res 1993 53: 4505-4510. [Abstract] [PDF]  

Human Papillomavirus 16 Immortalization of Normal Human Ectocervical Epithelial Cells Alters Retinoic Acid Regulation of Cell Growth and Epidermal Growth Factor Receptor Expression

Nywana Sizemore and Ellen A. Rorke
Cancer Res 1993 53: 4511-4517. [Abstract] [PDF]  

Chronic Radiation-induced Alteration in Hematopoietic Repair during Preclinical Phases of Aplastic Anemia and Myeloproliferative Disease: Assessing Unscheduled DNA Synthesis Responses

Thomas M. Seed and Susan M. Meyers
Cancer Res 1993 53: 4518-4527. [Abstract] [PDF]  

Inhibition of Oxidative Stress in HeLa Cells by Chemopreventive Agents

Ramesh S. Bhimani, Walter Troll, Dezider Grunberger, and Krystyna Frenkel
Cancer Res 1993 53: 4528-4533. [Abstract] [PDF]  

Major Difference in the Hepatocarcinogenicity and DNA Adduct Forming Ability between Toremifene and Tamoxifen in Female Crl:CD(BR) Rats

Gordon C. Hard, Michael J. Iatropoulos, Kevin Jordan, Leila Radi, Olgierd P. Kaltenberg, Anthony R. Imondi, and Gary M. Williams
Cancer Res 1993 53: 4534-4541. [Abstract] [PDF]  

Regulation of Protein Kinase C Isozymes in Kidney Regeneration

Liqun Dong, James L. Stevens, Doriano Fabbro, and Susan Jaken
Cancer Res 1993 53: 4542-4549. [Abstract] [PDF]  

Expression and Prognostic Significance of Platelet-derived Growth Factor and Its Receptors in Epithelial Ovarian Neoplasms

Rudi Henriksen, Keiko Funa, Erik Wilander, Torbjörn Bäckström, Mona Ridderheim, and Kjell Öberg
Cancer Res 1993 53: 4550-4554. [Abstract] [PDF]  

A Phase I Clinical Trial of Murine Monoclonal Antibody D612 in Patients with Metastatic Gastrointestinal Cancer

Mansoor N. Saleh, M. B. Khazaeli, William E. Grizzle, Richard H. Wheeler, Sharon Lawson, Tiepu Liu, Charles Russell, Ruby Meredith, Jeffrey Schlom, and Albert F. LoBuglio
Cancer Res 1993 53: 4555-4562. [Abstract] [PDF]  

Inhibition of the in Vivo Conversion of Androstenedione to Estrone by the Aromatase Inhibitor Vorozole in Healthy Postmenopausal Women

Elsken van der Wall, Truus H. Donker, Edwin de Frankrijker, Hans W. Nortier, Jos H. H. Thijssen, and Marinus A. Blankenstein
Cancer Res 1993 53: 4563-4566. [Abstract] [PDF]  

Modulation of Cytotoxicity and Cellular Pharmacology of 1,2-Diaminocyclohexane Platinum(IV) Complexes Mediated by Axial and Equatorial Ligands

Yuichiro Kido, Abdul R. Khokhar, Salaam Al-Baken, and Zahid H. Siddik
Cancer Res 1993 53: 4567-4572. [Abstract] [PDF]  

Estramustine Depolymerizes Microtubules by Binding to Tubulin

Björn Dahllöf, Anita Billström, Fernando Cabral, and Beryl Hartley-Asp
Cancer Res 1993 53: 4573-4581. [Abstract] [PDF]  

Effect of a Template-located 2',2'-Difluorodeoxycytidine on the Kinetics and Fidelity of Base Insertion by Klenow (3'5'Exonuclease^-) Fragment

William E. Schy, Larry W. Hertel, Julian S. Kroin, Linda B. Bloom, Myron F. Goodman, and Frank C. Richardson
Cancer Res 1993 53: 4582-4587. [Abstract] [PDF]  

Polyethylene Glycol-modified Chimeric Toxin Composed of Transforming Growth Factor and Pseudomonas Exotoxin

Qing-cheng Wang, Lee H. Pai, Waldemar Debinski, David J. FitzGerald, and Ira Pastan
Cancer Res 1993 53: 4588-4594. [Abstract] [PDF]  

In Vitro and in Vivo Reversal of Multidrug Resistance by GF120918, an Acridonecarboxamide Derivative

François Hyafil, Catherine Vergely, Pierre Du Vignaud, and Thierry Grand-Perret
Cancer Res 1993 53: 4595-4602. [Abstract] [PDF]  

Cardioprotective Properties of O-(β-Hydroxyethyl)-rutosides in Doxorubicin-pretreated BALB/c Mice

Saskia A. B. E. van Acker, Emile E. Voest, Dolf B. Beems, Henk T. Madhuizen, Jan de Jong, Aalt Bast, and Wim J. F. van der Vijgh
Cancer Res 1993 53: 4603-4607. [Abstract] [PDF]  

Main Drug- and Carcinogen-metabolizing Enzyme Systems in Human Non-Small Cell Lung Cancer and Peritumoral Tissues

Caroline Toussaint, Nicolas Albin, Liliane Massaad, Dominique Grunenwald, Orlando Parise,, Jr., Jackie Morizet, Alain Gouyette, and Guy G. Chabot
Cancer Res 1993 53: 4608-4612. [Abstract] [PDF]  

Caffeine Prevents Apoptosis and Cell Cycle Effects Induced by Camptothecin or Topotecan in HL-60 Cells

Frank Traganos, Jan Kapuscinski, Jianping Gong, Barbara Ardelt, Robert J. Darzynkiewicz, and Zbigniew Darzynkiewicz
Cancer Res 1993 53: 4613-4618. [Abstract] [PDF]  

In Vivo Antitumor Activity of 5-Fluorocytosine on Human Colorectal Carcinoma Cells Genetically Modified to Express Cytosine Deaminase

Brian E. Huber, Elizabeth A. Austin, Steven S. Good, Vincent C. Knick, Stephen Tibbels, and Cynthia A. Richards
Cancer Res 1993 53: 4619-4626. [Abstract] [PDF]  

Reversible Inhibition of Proliferation of Epithelial Cell Lines by Agaricus bisporus (Edible Mushroom) Lectin

Lugang Yu, David G. Fernig, John A. Smith, Jeremy D. Milton, and Jonathan M. Rhodes
Cancer Res 1993 53: 4627-4632. [Abstract] [PDF]  

Tumor-specific, Schedule-dependent Interaction between Tirapazamine (SR 4233) and Cisplatin

Mary Jo Done and J. Martin Brown
Cancer Res 1993 53: 4633-4636. [Abstract] [PDF]  

Antitumor Effect of Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies plus cis-Diamminedichloroplatinum on Well Established A431 Cell Xenografts

Zhen Fan, Jose Baselga, Hideo Masui, and John Mendelsohn
Cancer Res 1993 53: 4637-4642. [Abstract] [PDF]  

Inhibitory Effect of Interleukin 4 on Production of Interleukin 6 by Adult T-Cell Leukemia Cells

Naoki Mori, Fumihiko Shirakawa, Shuichi Murakami, Susumu Oda, and Sumiya Eto
Cancer Res 1993 53: 4643-4647. [Abstract] [PDF]  

Immune Reactions against Hepatitis B Viral Antigens Lead to the Rejection of Hepatocellular Carcinoma in BALB/c Mice

Shu-Hsia Chen, Cheng-po Hu, Chien-Kuo Lee, and Chungming Chang
Cancer Res 1993 53: 4648-4651. [Abstract] [PDF]  

Interferon--induced Intercellular Adhesion Molecule-1: Expression on Human Tumor Cells Enhances Bifunctional Antibody-mediated Lysis through a Lymphocyte Function-associated Antigen-1 Dependent Mechanism

Patrick S. Ramsey, Phillip A. Dean, Aliza Tasimowicz-Alpini, John H. Donohue, and Heidi Nelson
Cancer Res 1993 53: 4652-4657. [Abstract] [PDF]  

Effect of Verapamil on Doxorubicin Cardiotoxicity: Altered Muscle Gene Expression in Cultured Neonatal Rat Cardiomyocytes

Hajime Akimoto, Nicholas A. Bruno, Doris L. Slate, Margaret E. Billingham, Suzy V. Torti, and Frank M. Torti
Cancer Res 1993 53: 4658-4664. [Abstract] [PDF]  

p53 Mutations and Histological Type of Invasive Breast Carcinoma

Antonio Marchetti, Fiamma Buttitta, Silvia Pellegrini, Daniela Campani, Francesca Diella, Denise Cecchetti, Robert Callahan, and Maria Bistocchi
Cancer Res 1993 53: 4665-4669. [Abstract] [PDF]  

Up-Regulation of Lysyl Oxidase in Spontaneous Revertants of H-ras-transformed Rat Fibroblasts

Alex Hajnal, Roman Klemenz, and Reinhold Schäfer
Cancer Res 1993 53: 4670-4675. [Abstract] [PDF]  

Clonal Analysis by Study of X Chromosome Inactivation in Formalin-fixed Paraffin-embedded Tissue

Robert D. Mashal, Susan C. Lester, and Jeffrey Sklar
Cancer Res 1993 53: 4676-4679. [Abstract] [PDF]  

Role for Membrane and Secreted Insulin-like Growth Factor-binding Protein-2 in the Regulation of Insulin-like Growth Factor Action in Lung Tumors

Julie G. Reeve, Julie Morgan, Jurg Schwander, and Norman M. Bleehen
Cancer Res 1993 53: 4680-4685. [Abstract] [PDF]  

Effect of Diets Containing Different Levels of Linoleic Acid on Human Breast Cancer Growth and Lung Metastasis in Nude Mice

David P. Rose, Mary Ann Hatala, Jeanne M. Connolly, and Jodie Rayburn
Cancer Res 1993 53: 4686-4690. [Abstract] [PDF]  

Expression of p53 Gene in 184 Unifocal Hepatocellular Carcinomas: Association with Ttomor Growth and Invasiveness

Hey-Chi Hsu, Hwai-Jung Tseng, Po-Lin Lai, Po-Huang Lee, and Shian-Yang Peng
Cancer Res 1993 53: 4691-4694. [Abstract] [PDF]  

Role of Platelet Membrane Glycoproteins Ib/IX and Ilb/IIIa, and of Platelet -Granule Proteins in Platelet Aggregation Induced by Human Osteosarcoma Cells

Philippe Clezardin, Jeanne Drouin, Marie-Christine Morel-Kopp, Michel Hanss, Beate Kehrel, Claire-Marie Serre, Cécile Kaplan, and Pierre D. Delmas
Cancer Res 1993 53: 4695-4700. [Abstract] [PDF]  

Investigation of the Subcellular Distribution of the bcl-2 Oncoprotein: Residence in the Nuclear Envelope, Endoplasmic Reticulum, and Outer Mitochondrial Membranes

Stanislaw Krajewski, Shigeki Tanaka, Shinichi Takayama, Matthew J. Schibler, Wayne Fenton, and John C. Reed
Cancer Res 1993 53: 4701-4714. [Abstract] [PDF]  

Immunodetection of Endogenous Opioid Peptides in Human Brain Tumors and Associated Cyst Fluids

Thierry Gustin, Thomas Bachelot, Jean-Marc G. Verna, Laurent F. Molin, Jean-Frangois M. Brunet, Francois R. Berger, and Alim L. Benabid
Cancer Res 1993 53: 4715-4719. [Abstract] [PDF]  

A Novel M_r 32,000 Nuclear Phosphoprotein Is Selectively Expressed in Cells Competent for Self-Renewal

Loren D. Walensky, Donald S. Coffey, Tseng-Hui Chen, Tzyy-Choou Wu, and Gary R. Pasternack
Cancer Res 1993 53: 4720-4726. [Abstract] [PDF]  

Expression of Vascular Permeability Factor (Vascular Endothelial Growth Factor) and Its Receptors in Adenocarcinomas of the Gastrointestinal Tract

Lawrence F. Brown, Brygida Berse, Robert W. Jackman, Kathi Tognazzi, Eleanor J. Manseau, Donald R. Senger, and Harold F. Dvorak
Cancer Res 1993 53: 4727-4735. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 4736-4738. [PDF]  

Erratum

Cancer Res 1993 53: 4738 [PDF]  

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