Advances in Brief:

Aberrant Expression of Type I Fibroblast Growth Factor Receptor in Human Pancreatic Adenocarcinomas

Michael S. Kobrin, Yoichiro Yamanaka, Helmut Friess, Martha E. Lopez, and Murray Korc
Cancer Res 1993 53: 4741-4744. [Abstract] [PDF]  

Evidence for Oligoclonal T-Cell Response in a Metastasis of Renal Cell Carcinoma Responding to Vaccination with Autologous Tumor Cells and Transfer of in Vitro-sensitized Vaccine-draining Lymph Node Lymphocytes

Eckhart Weidmann, Theodore F. Logan, Satoshi Yasumura, John M. Kirkwood, Massimo Trucco, and Theresa L. Whiteside
Cancer Res 1993 53: 4745-4749. [Abstract] [PDF]  

A Single Amino Acid Change in Human O⁶-Alkylguanine-DNA Alkyltransferase Decreasing Sensitivity to Inactivation by O⁶-Benzylguanine

Tina M. Crone and Anthony E. Pegg
Cancer Res 1993 53: 4750-4753. [Abstract] [PDF]  

Expression of CD44 Variant Proteins in Human Colorectal Cancer Is Related to Tumor Progression

Vera J. M. Wielenga, Karl-Heinz Heider, G. Johan, A. Offerhaus, Günther R. Adolf, Frank M. van den Berg, Helmut Ponta, Peter Herrlich, and Steven T. Pals
Cancer Res 1993 53: 4754-4756. [Abstract] [PDF]  

Altered trans-Activational Properties of a Mutated WT1 Gene Product in a WAGR-associated Wilms' Tumor

Seon Park, Gail Tomlinson, Perry Nisen, and Daniel A. Haber
Cancer Res 1993 53: 4757-4760. [Abstract] [PDF]  

Homozygous Deletions within 9p21-p22 Identify a Small Critical Region of Chromosomal Loss in Human Malignant Mesotheliomas

Jin Quan Cheng, Suresh C. Jhanwar, You Yong Lu, and Joseph R. Testa
Cancer Res 1993 53: 4761-4763. [Abstract] [PDF]  

Dexamethasone Reduces the Interstitial Fluid Pressure in a Human Colon Adenocarcinoma Xenograft

Paul E. G. Kristjansen, Yves Boucher, and Rakesh K. Jain
Cancer Res 1993 53: 4764-4766. [Abstract] [PDF]  

Prevention of Carcinogenicity of Anticancer Drugs by Metallothionein Induction

Masahiko Satoh, Yukihiro Kondo, Masaharu Mita, Ippei Nakagawa, Akira Naganuma, and Nobumasa Imura
Cancer Res 1993 53: 4767-4768. [Abstract] [PDF]  

The Synthetic Retinoid Fenretinide Lowers Plasma Insulin-like Growth Factor I Levels in Breast Cancer Patients

Rosalba Torrisi, Floriana Pensa, Maria Antonietta Orengo, Elie Catsafados, Paola Ponzani, Francesco Boccardo, Alberto Costa, and Andrea Decensi
Cancer Res 1993 53: 4769-4771. [Abstract] [PDF]  

Inactive p53 Mutants May Enhance the Transcriptional Activity of Wild-Type p53

Wei Zhang, Jerry W. Shay, and Albert Deisseroth
Cancer Res 1993 53: 4772-4775. [Abstract] [PDF]  

Role of the p53 Tumor Suppressor Gene in Cell Cycle Arrest and Radiosensitivity of Burkitt's Lymphoma Cell Lines

Patrick M. O'Connor, Joany Jackman, Daniel Jondle, Kishor Bhatia, Ian Magrath, and Kurt W. Kohn
Cancer Res 1993 53: 4776-4780. [Abstract] [PDF]  

Maintenance of Genomic Imprinting at the IGF2 Locus in Hepatoblastoma

Stella M. Davies
Cancer Res 1993 53: 4781-4783. [Abstract] [PDF]  

Biochemistry and Biophysics:

Molecular and Cellular Interactions between Intoplicine, DNA, and Topoisomerase II Studied by Surface-enhanced Raman Scattering Spectroscopy

Hamid Morjani, Jean-François Riou, Igor Nabiev, François Lavelle, and Michel Manfait
Cancer Res 1993 53: 4784-4790. [Abstract] [PDF]  

Monoclonal Antibody 2B5 Defines a Truncated O-Glycan, GlcNAcß1-3Galß1-4GlcNAcß1-6 (GalNAc), on Mucins from Deep Gastric and Duodenal Glands as Well as Metaplasia and Neoplasia of Gastric Differentiation

F-G. Hanisch, U. Koldovsky, and F. Borchard
Cancer Res 1993 53: 4791-4796. [Abstract] [PDF]  

Carcinogenesis:

Immortalization of Syrian Hamster Embryo Cells: Probabilistic Event or Deterministic Process

Bart L. M. C. Bols, Karin C. P. M. Gillis, Jolanda M. Naaktgeboren, Paul H. M. Lohman, Matthieu Niericker, and Johannes W. I. M. Simons
Cancer Res 1993 53: 4797-4802. [Abstract] [PDF]  

The Suprabasal Expression of 6ß4 Integrin Is Associated with a High Risk for Malignant Progression in Mouse Skin Carcinogenesis

Tamar Tennenbaum, Arin K. Weiner, Adam J. Belanger, Adam B. Glick, Henry Hennings, and Stuart H. Yuspa
Cancer Res 1993 53: 4803-4810. [Abstract] [PDF]  

HPV-16, Tobacco-specific N-Nitrosamine, and N-Methyl-N'-nitro-N-nitrosoguanidine in Oral Carcinogenesis

Myong Soo Kim, Ki-Hyuk Shin, Jeong-Hwa Baek, Henry M. Cherrick, and No-Hee Park
Cancer Res 1993 53: 4811-4816. [Abstract] [PDF]  

p53 Protein Accumulates Frequently in Early Bronchial Neoplasia

W. P. Bennett, T. V. Colby, W. D. Travis, A. Borkowski, R. T. Jones, D. P. Lane, R. A. Metcalf, J. M. Samet, Y. Takeshima, J. R. Gu, K. H. Vähäkangas, Y. Soini, P. Pääkkö, J. A. Welsh, B. F. Trump, and C. C. Harris
Cancer Res 1993 53: 4817-4822. [Abstract] [PDF]  

Clinical Investigations:

High-Risk Human Papillomavirus Infections and Overexpression of p53 Protein as Prognostic Indicators in Transitional Cell Carcinoma of the Urinary Bladder

Mutsuo Furihata, Keiji Inoue, Yuji Ohtsuki, Hirofumi Hashimoto, Naotami Terao, and Yukitoshi Fujita
Cancer Res 1993 53: 4823-4827. [Abstract] [PDF]  

A Phase I Study of Continuous Infusion 5-Fluorouracil plus Calcium Leucovorin in Combination with N-(Phosphonacetyl)-L-aspartate in Metastatic Gastrointestinal Adenocarcinoma

J. L. Grem, N. McAtee, S. M. Steinberg, J. M. Hamilton, R. F. Murphy, J. Drake, T. Chisena, F. Balis, R. Cysyk, S. G. Arbuck, J. M. Sorensen, A. P. Chen, L. Goldstein, E. Jordan, A. Setser, B. Goldspiel, M. DeCarvalho, and C. J. Allegra
Cancer Res 1993 53: 4828-4836. [Abstract] [PDF]  

Phase I Pharmacokinetic Study of Cyclosporin A Combined with Doxorubicin

Charles Erlichman, Malcolm Moore, Jake J. Thiessen, Ian G. Kerr, Scott Walker, Phyllis Goodman, Georg Bjarnason, Carlo DeAngelis, and Peter Bunting
Cancer Res 1993 53: 4837-4842. [Abstract] [PDF]  

Phase I Evaluation and Pharmacokinetic Study of Pyrazine-2-diazohydroxide Administered as a Single Bolus Intravenous Injection in Patients with Advanced Solid Tumors

Jeffrey G. Supko, S. P. Balcerzak, and Eric H. Kraut
Cancer Res 1993 53: 4843-4849. [Abstract] [PDF]  

Plasma and Cellular Pharmacokinetics of Mitoxantrone in High-Dose Chemotherapeutic Regimen for Refractory Lymphomas

Pierre Canal, Michel Attal, Etienne Chatelut, Sylvie Guichard, Françoise Huguet, Catherine Muller, Daniel Schlaifer, Guy Laurent, Georges Houin, and Roland Bugat
Cancer Res 1993 53: 4850-4854. [Abstract] [PDF]  

Endocrinology:

Human Prostatic Inhibin Suppresses Tumor Growth and Inhibits Clonogenic Cell Survival of a Model Prostatic Adenocarcinoma, the Dunning R3327G Rat Tumor

Balakrishna L. Lokeshwar, Kalpana S. Hurkadli, Anil R. Sheth, and Norman L. Block
Cancer Res 1993 53: 4855-4859. [Abstract] [PDF]  

Epidemiology:

A Prospective Cohort Study on Selenium Status and the Risk of Lung Cancer

Piet A. van den Brandt, R. Alexandra Goldbohm, Pieter van 't Veer, Peter Bode, Elisabeth Dorant, Rudolph J. J. Hermus, and Ferd Sturmans
Cancer Res 1993 53: 4860-4865. [Abstract] [PDF]  

Experimental Therapeutics:

Altered Topoisomerase II in a Drug-resistant Small Cell Lung Cancer Cell Line Selected in VP-16

Shelagh E. L. Mirski, Cindy D. Evans, Kurt C. Almquist, Marilyn L. Slovak, and Susan P. C. Cole
Cancer Res 1993 53: 4866-4873. [Abstract] [PDF]  

Metallothionein: A Protein Conferring Resistance in Vitro to Tumor Necrosis Factor

Karen Leyshon-Sørland, Lars Mørkrid, and Hans Erik Rugstad
Cancer Res 1993 53: 4874-4880. [Abstract] [PDF]  

Etoposide Pharmacokinetics in Children: The Development and Prospective Validation of a Dosing Equation

Stephen P. Lowis, Andrew D. J. Pearson, David R. Newell, and Michael Cole
Cancer Res 1993 53: 4881-4889. [Abstract] [PDF]  

Development of a Novel Spontaneous Metastasis Model of Human Osteosarcoma Transplanted Orthotopically into Bone of Athymic Mice

Örjan Berlin, Dvorit Samid, Rakesh Donthineni-Rao, Wayne Akeson, David Amiel, and Virgil L. Woods, Jr.
Cancer Res 1993 53: 4890-4895. [Abstract] [PDF]  

Inhibition of Experimental Metastasis by an -Glucosidase Inhibitor, 1,6-Epi-cyclophellitol

Sonoko Atsumi, Chisato Nosaka, Yusuke Ochi, Hironobu Iinuma, and Kazuo Umezawa
Cancer Res 1993 53: 4896-4899. [Abstract] [PDF]  

Expression of a Rat Glutathione-S-transferase Complementary DNA in Rat Mammary Carcinoma Cells: Impact upon Alkylator-induced Toxicity

Robyn L. Schecter, Moulay A. Alaoui-Jamali, Annie Woo, William E. Fahl, and Gerald Batist
Cancer Res 1993 53: 4900-4906. [Abstract] [PDF]  

Reductive Activation of Mitomycin C by NADH:Cytochrome b₅ Reductase

William F. Hodnick and Alan C. Sartorelli
Cancer Res 1993 53: 4907-4912. [Abstract] [PDF]  

Cellular Pharmacology of Liposomal cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum(II) in A2780/S and A2780/PDD Cells

Insook Han, Yi-He Ling, Salaam Al-Baker, Abdul R. Khokhar, and Roman Perez-Soler
Cancer Res 1993 53: 4913-4919. [Abstract] [PDF]  

Immunology:

Expression of a Recombinant Breast Tumor-associated Mucin Fusion Protein in Escherichia coli Exposes the Tumor-specific Epitope

Peisheng Hu and Stephen E. Wright
Cancer Res 1993 53: 4920-4926. [Abstract] [PDF]  

Clinical Relevance of ICAM-1 Expression in Primary Lesions and Serum of Patients with Malignant Melanoma

Toshiro Kageshita, Akira Yoshii, Toru Kimura, Norikazu Kuriya, Tomomichi Ono, Masayuki Tsujisaki, Kohzo Imai, and Soldano Ferrone
Cancer Res 1993 53: 4927-4932. [Abstract] [PDF]  

Human Cytotoxic T-Cells Suppress the Growth of Spontaneous Melanoma Metastases in SCID/hu Mice

Helen Sabzevari and Ralph A. Reisfeld
Cancer Res 1993 53: 4933-4937. [Abstract] [PDF]  

Molecular Biology and Genetics:

The Expression of Mouse Biliary Glycoprotein, a Carcinoembryonic Antigen-related Gene, Is Down-Regulated in Malignant Mouse Tissues

Madelaine Rosenberg, Patrick Nédellec, Serge Jothy, David Fleiszer, Claire Turbide, and Nicole Beauchemin
Cancer Res 1993 53: 4938-4945. [Abstract] [PDF]  

Multiple Mechanisms of N-(Phosphonoacetyl)-L-aspartate Drug Resistance in SV40-infected Precrisis Human Fibroblasts

Deborah I. Schaefer, Elizabeth M. Livanos, Alicia E. White, and Thea D. Tlsty
Cancer Res 1993 53: 4946-4951. [Abstract] [PDF]  

Hyperthermia Induces Resistance to Ultraviolet Light B in Primary and Immortalized Epidermal Keratinocytes

Edward V. Maytin, Laura A. Murphy, and Melissa A. Merrill
Cancer Res 1993 53: 4952-4959. [Abstract] [PDF]  

Tumor Biology:

Her-2/neu Expression in Node-negative Breast Cancer: Direct Tissue Quantitation by Computerized Image Analysis and Association of Overexpression with Increased Risk of Recurrent Disease

Michael F. Press, Malcolm C. Pike, Victoria R. Chazin, Gene Hung, Judith A. Udove, Mitchell Markowicz, John Danyluk, William Godolphin, Mark Sliwkowski, Robert Akita, Malcolm C. Paterson, and Dennis J. Slamon
Cancer Res 1993 53: 4960-4970. [Abstract] [PDF]  

Altered Extracellular Matrices Influence Cellular Processes and Nuclear Matrix Organizations of Overlying Human Bladder Urothelial Cells

Jeffrey N. Gordon, Wei-Ping Shu, Richard N. Schlussel, Michael J. Droller, and Brian C-S. Liu
Cancer Res 1993 53: 4971-4977. [Abstract] [PDF]  

Regulation of Bcl-2 Oncoprotein Levels with Differentiation of Human Neuroblastoma Cells

Motoi Hanada, Stanislaw Krajewski, Shigeki Tanaka, Dominique Cazals-Hatem, Barbara A. Spengler, Robert A. Ross, June L. Biedler, and John C. Reed
Cancer Res 1993 53: 4978-4986. [Abstract] [PDF]  

E-Cadherin: A Differentiation Marker in Thyroid Malignancies

G. Brabant, C. Hoang-Vu, Y. Cetin, H. Dralle, G. Scheumann, J. Mölne, G. Hansson, S. Jansson, L. E. Ericson, and M. Nilsson
Cancer Res 1993 53: 4987-4993. [Abstract] [PDF]  

Mitochondrial Alterations in Photodynamic Therapy-resistant Cells

Sheila M. Sharkey, Brian C. Wilson, Roger Moorehead, and Gurmit Singh
Cancer Res 1993 53: 4994-4999. [Abstract] [PDF]  

Proliferating Cell Nuclear Antigen Expression and Argyrophilic Nucleolar Organizer Regions as Factors Influencing Prognosis of Surgically Treated Lung Cancer Patients

Teruyoshi Ishida, Satoshi Kaneko, Kouhei Akazawa, Masahiro Tateishi, Kenji Sugio, and Keizo Sugimachi
Cancer Res 1993 53: 5000-5003. [Abstract] [PDF]  

Estrogen Inhibits the Growth of Estrogen Receptor-negative, but not Estrogen Receptor-positive, Human Mammary Epithelial Cells Expressing a Recombinant Estrogen Receptor

Deborah A. Zajchowski, Ruth Sager, and Lynn Webster
Cancer Res 1993 53: 5004-5011. [Abstract] [PDF]  

Quantitative Comparison between the Transplantability of Human and Murine Tumors into the Subcutaneous Tissue of NCr/Sed-nu/nu Nude and Severe Combined Immunodeficient Mice

Alphonse Taghian, Wilfried Budach, Anthony Zietman, Jill Freeman, Danielle Gioioso, Wlodzimierz Ruka, and Herman D. Suit
Cancer Res 1993 53: 5012-5017. [Abstract] [PDF]  

Quantitative Comparison between the Transplantability of Human and Murine Tumors into the Brain of NCr/Sed-nu/nu Nude and Severe Combined Immunodeficient Mice

Alphonse Taghian, Wilfried Budach, Anthony Zietman, Jill Freeman, Danielle Gioioso, and Herman D. Suit
Cancer Res 1993 53: 5018-5021. [Abstract] [PDF]  

Suppression of T-Lymphoma Cell Apoptosis by Monoclonal Antibodies Raised against Cell Surface Adhesion Molecules

Naoya Fujita, Shiro Kataoka, Mikihiko Naito, Yuji Heike, Narikazu Boku, Motowo Nakajima, and Takashi Tsuruo
Cancer Res 1993 53: 5022-5027. [Abstract] [PDF]  

Progressive Ovarian Carcinoma Induces Synthesis of Type I and Type III Procollagens in the Tumor Tissue and Peritoneal Cavity

Guo-Guang Zhu, Juha Risteli, Ulla Puistola, Antti Kauppila, and Leila Risteli
Cancer Res 1993 53: 5028-5032. [Abstract] [PDF]  

Regulation of the Expression of Galactoside-binding Lectin during Human Monocytic Differentiation

Pratima Nangia-Makker, Josiah Ochieng, Judith K. Christman, and Avraham Raz
Cancer Res 1993 53: 5033-5037. [Abstract] [PDF]  

Increased Expression of Nucleoside Diphosphate Kinase/nm23 and c-Ha-ras mRNA Is Associated with Spontaneous Lung Metastasis in Rat-transplantable Osteosarcomas

Kanya Honoki, Masahiro Tsutsumi, Yoshizumi Miyauchi, Yoshio Mii, Toshifumi Tsujiuchi, Toru Morishita, Syuichi Miura, Makoto Aoki, Eisaku Kobayashi, Susumu Tamai, and Yoichi Konishi
Cancer Res 1993 53: 5038-5042. [Abstract] [PDF]  

Analysis of the Functional Role of Chromosome 10 Loss in Human Glioblastomas

Mark A. Pershouse, Elton Stubblefield, Azra Hadi, Ann M. Killary, W. K. Alfred Yung, and Peter A. Steck
Cancer Res 1993 53: 5043-5050. [Abstract] [PDF]  

Interleukin 1 Receptor Antagonist Inhibits the Augmentation of Metastasis Induced by Interleukin 1 or Lipopolysaccharide in a Human Melanoma/Nude Mouse System

Renato G. S. Chirivi, Angela Garofalo, Ines Martin Padura, Alberto Mantovani, and Raffaella Giavazzi
Cancer Res 1993 53: 5051-5054. [Abstract] [PDF]  

Meeting Report:

Molecular Mechanisms of Tumor Development and Progression: New Targets for Prevention, Diagnosis, and Therapy—A Pathology B Study Section Workshop

Philip Furmanski, Chester J. Herman, and Martin Padarathsingh
Cancer Res 1993 53: 5055-5059. [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 5060-5063. [PDF]  

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