Advances in Brief:

Protective and Curative Potential of Vaccination with Interleukin-2-Gene-transfected Cells from a Spontaneous Mouse Mammary Adenocarcinoma

Federica Cavallo, Francesco Di Pierro, Mirella Giovarelli, Alberto Gulino, Alessandra Vacca, Antonella Stoppacciaro, Marco Forni, Andrea Modesti, and Guido Forni
Cancer Res 1993 53: 5067-5070. [Abstract] [PDF]  

Cooperation between v-fos and v-ras^HA Induces Autonomous Papillomas in Transgenic Epidermis but not Malignant Conversion

David A. Greenhalgh, Maria I. Quintanilla, Christine C. Orengo, Jennifer L. Barber, Joshua N. Eckhardt, Joseph A. Rothnagel, and Dennis R. Roop
Cancer Res 1993 53: 5071-5075. [Abstract] [PDF]  

Polymerase Chain Reaction Analysis of Parathyroid Hormone-related Protein Gene Expression in Breast Cancer Patients and Occurrence of Bone Metastases

Zhor Bouizar, Frédérique Spyratos, Stéphanie Deytieux, Marie-Christine de Vernejoul, and Annick Jullienne
Cancer Res 1993 53: 5076-5078. [Abstract] [PDF]  

Coexistence of Somatic and Germ-Line Mutations of APC Gene in Desmoid Tumors from Patients with Familial Adenomatous Polyposis

Michiko Miyaki, Motoko Konishi, Rei Kikuchi-Yanoshita, Masayuki Enomoto, Kiyoko Tanaka, Hiromi Takahashi, Masatoshi Muraoka, Takeo Mori, Fumio Konishi, and Takeo Iwama
Cancer Res 1993 53: 5079-5082. [Abstract] [PDF]  

Linkage Analysis of DRD2, a Marker Linked to the Ataxia-Telangiectasia Gene, in 64 Families with Premenopausal Bilateral Breast Cancer

Victoria Cortessis, Sue Ingles, Robert Millikan, Anh Diep, Richard A. Gatti, Lesley Richardson, W. Douglas Thompson, Annlia Paganini-Hill, Robert S. Sparkes, and Robert W. Haile
Cancer Res 1993 53: 5083-5086. [Abstract] [PDF]  

Genetic Instability in Pancreatic Cancer and Poorly Differentiated Type of Gastric Cancer

Hye-Jung Han, Akio Yanagisawa, Yo Kato, Jae-Gahb Park, and Yusuke Nakamura
Cancer Res 1993 53: 5087-5089. [Abstract] [PDF]  

High Affinity Binding Sites for Gastrin Releasing Peptide on Human Gastric Cancer and Ménétrier's Mucosa

Shaun R. Preston, Linda F. Woodhouse, Steven Jones-Blackett, Judy I. Wyatt, and John N. Primrose
Cancer Res 1993 53: 5090-5092. [Abstract] [PDF]  

Evidence for Two Bladder Cancer Suppressor Loci on Human Chromosome 9

J. Michael Ruppert, Kaori Tokino, and David Sidransky
Cancer Res 1993 53: 5093-5095. [Abstract] [PDF]  

Simultaneous Analysis of Cell Cycle Kinetics at Two Different DNA Ploidy Levels Based on DNA Content and Cyclin B Measurements

Jianping Gong, Frank Traganos, and Zbigniew Darzynkiewicz
Cancer Res 1993 53: 5096-5099. [Abstract] [PDF]  

Genetic Instability of Microsatellites in Endometrial Carcinoma

John I. Risinger, Andrew Berchuck, Matthew F. Kohler, Patrice Watson, Henry T. Lynch, and Jeff Boyd
Cancer Res 1993 53: 5100-5103. [Abstract] [PDF]  

Elevated Production of Active Oxygen in Bloom's Syndrome Cell Lines

Thomas Nicotera, Kuldip Thusu, and Paresh Dandona
Cancer Res 1993 53: 5104-5107. [Abstract] [PDF]  

Fusion of PAX3 to a Member of the Forkhead Family of Transcription Factors in Human Alveolar Rhabdomyosarcoma

David N. Shapiro, Jack E. Sublett, Baitao Li, James R. Downing, and Clayton W. Naeve
Cancer Res 1993 53: 5108-5112. [Abstract] [PDF]  

Special Lecture:

Recent Advances in Head and Neck Cancer—Larynx Preservation and Cancer Chemoprevention: The Seventeenth Annual Richard and Hinda Rosenthal Foundation Award Lecture

Waun Ki Hong, Scott M. Lippman, and Gregory T. Wolf
Cancer Res 1993 53: 5113-5120. [PDF]  

Biochemistry and Biophysics:

Involvement of Human Liver Cytochrome P450 3A in Vinblastine Metabolism: Drug Interactions

Xin-Ru Zhou-Pan, Eric Sérée, Xiao-Jian Zhou, Michel Placidi, Patrick Maurel, Yves Barra, and Roger Rahmani
Cancer Res 1993 53: 5121-5126. [Abstract] [PDF]  

Adducts of Mitomycin C and DNA in EMT6 Mouse Mammary Tumor Cells: Effects of Hypoxia and Dicumarol on Adduct Patterns

Roland Bizanek, Dondapati Chowdary, Hitoshi Arai, Masaji Kasai, Christine S. Hughes, Alan C. Sartorelli, Sara Rockwell, and Maria Tomasz
Cancer Res 1993 53: 5127-5134. [Abstract] [PDF]  

Cytochrome P-450-induced Cytotoxicity of Mitoxantrone by Formation of Electrophilic Intermediates

Kersten Mewes, Joachim Blanz, Gerhard Ehninger, Rolf Gebhardt, and Klaus-Peter Zeller
Cancer Res 1993 53: 5135-5142. [Abstract] [PDF]  

Purine Nucleotide Levels in Host Tissue of Ehrlich Ascites Tumor-bearing Mice in Different Growth Phases of the Tumor

Werner G. Siems, Tilman Grune, Heike Schmidt, Yuri V. Tikhonov, and Alexej M. Pimenov
Cancer Res 1993 53: 5143-5147. [Abstract] [PDF]  

Inhibitory Effects of -Interferon on Epidermal Growth Factor-mediated Receptor-dependent Events

E. N. Fish, J. Ghislain, J. Trogadis, and J. K. Stevens
Cancer Res 1993 53: 5148-5157. [Abstract] [PDF]  

Carcinogenesis:

Migratory Pattern of Fetal Rat Brain Cells and Human Glioma Cells in the Adult Rat Brain

Paal-Henning Pedersen, Kirsten Marienhagen, Sverre Mørk, and Rolf Bjerkvig
Cancer Res 1993 53: 5158-5165. [Abstract] [PDF]  

Insulin-like Growth Factor II and WT1 Transcript Localization in Human Fetal Kidney and Wilms' Tumor

Kankatsu Yun, Andrew E. Fidler, Michael R. Eccles, and Anthony E. Reeve
Cancer Res 1993 53: 5166-5171. [Abstract] [PDF]  

Enhancement of Rat Urinary Bladder Tumorigenesis by Lipopolysaccharide-induced Inflammation

Koji Kawai, Masashi Yamamoto, Shuji Kameyama, Hitoshi Kawamata, Alfred Rademaker, and Ryoichi Oyasu
Cancer Res 1993 53: 5172-5175. [Abstract] [PDF]  

Clinical Investigations:

Phase I Trial of an Oral Immunomodulator and Interferon Inducer in Cancer Patients

Patricia L. Witt, Paul S. Ritch, Douglas Reding, Timothy L. McAuliffe, Linda Westrick, Sidney E. Grossberg, and Ernest C. Borden
Cancer Res 1993 53: 5176-5180. [Abstract] [PDF]  

Individualized Chemotherapy for Patients with Non-Small Cell Lung Cancer Determined by Prospective Identification of Neuroendocrine Markers and in Vitro Drug Sensitivity Testing

Gail L. Shaw, Adi F. Gazdar, Ruby Phelps, R. Ilona Linnoila, Daniel C. Ihde, Bruce E. Johnson, Herbert K. Oie, Harvey I. Pass, Seth M. Steinberg, Bimal C. Ghosh, Thomas E. Walsh, John C. Nesbitt, James D. Cotelingam, John D. Minna, and James L. Mulshine
Cancer Res 1993 53: 5181-5187. [Abstract] [PDF]  

Endocrinology:

Improved Prediction of Survival in Advanced Adenocarcinoma of the Ovary by Immunocytochemical Analysis and the Composition Adjusted Receptor Level of the Estrogen Receptor

Dirk G. Kieback, Susan K. McCamant, Michael F. Press, E. Neely Atkinson, Harry S. Gallager, Creighton L. Edwards, Richard A. Hajek, and Lovell A. Jones
Cancer Res 1993 53: 5188-5192. [Abstract] [PDF]  

Estrogen and Antiestrogen Modulation of MCF7 Human Breast Cancer Cell Proliferation Is Associated with Specific Alterations in Accumulation of Insulin-like Growth Factor-binding Proteins in Conditioned Media

Susan E. Pratt and Michael N. Pollak
Cancer Res 1993 53: 5193-5198. [Abstract] [PDF]  

Hormone Regulation of Human Prostate in Organ Culture

Marja T. Nevalainen, Pirkko L. Härkönen, Eeva M. Valve, Wu Ping, Martti Nurmi, and Paula M. Martikainen
Cancer Res 1993 53: 5199-5207. [Abstract] [PDF]  

CCK_A and CCK_B Receptors Are Expressed in Small Cell Lung Cancer Lines and Mediate Ca²⁺ Mobilization and Clonal Growth

Tariq Sethi, Thomas Herget, S. Vincent Wu, John H. Walsh, and Enrique Rozengurt
Cancer Res 1993 53: 5208-5213. [Abstract] [PDF]  

Thymosin 1 Down-regulates the Growth of Human Non-Small Cell Lung Cancer Cells in Vitro and in Vivo

Terry W. Moody, Mirela Fagarasan, Farah Zia, Mirjana Cesnjaj, and Allan L. Goldstein
Cancer Res 1993 53: 5214-5218. [Abstract] [PDF]  

Experimental Therapeutics:

Resistance to Fluorodeoxyuridine-induced DNA Damage and Cytotoxicity Correlates with an Elevation of Deoxyuridine Triphosphatase Activity and Failure to Accumulate Deoxyuridine Triphosphate

Christine E. Canman, Theodore S. Lawrence, Donna S. Shewach, Hsin-Yi Tang, and Jonathan Maybaum
Cancer Res 1993 53: 5219-5224. [Abstract] [PDF]  

Cross-Resistance to Diverse Drugs Is Associated with Primary Cisplatin Resistance in Ovarian Cancer Cell Lines

Kinya Hamaguchi, Andrew K. Godwin, Michiaki Yakushiji, Peter J. O'Dwyer, Robert F. Ozols, and Thomas C. Hamilton
Cancer Res 1993 53: 5225-5232. [Abstract] [PDF]  

Angiogenesis Inhibitor TNP-470 (AGM-1470) Potently Inhibits the Tumor Growth of Hormone-independent Human Breast and Prostate Carcinoma Cell Lines

Masuo Yamaoka, Toshihiro Yamamoto, Shuichi Ikeyama, Katsuichi Sudo, and Takeshi Fujita
Cancer Res 1993 53: 5233-5236. [Abstract] [PDF]  

Protection from Adriamycin Cytotoxicity in L1210 Cells by Brefeldin A

Paul J. Vichi and Thomas R. Tritton
Cancer Res 1993 53: 5237-5243. [Abstract] [PDF]  

Immunology:

Molecular Cloning of a Human Monoclonal Antibody Reactive to Ganglioside G_M3 Antigen on Human Cancers

Dave S. B. Hoon, Yuan Wang, Lan Sze, Hidetoshi Kanda, Takeshi Watanabe, Sherie L. Morrison, Donald L. Morton, and Reiko F. Irie
Cancer Res 1993 53: 5244-5250. [Abstract] [PDF]  

Molecular Biology and Genetics:

Neu Differentiation Factor (Heregulin) Induces Expression of Intercellular Adhesion Molecule 1: Implications for Mammary Tumors

Sarah S. Bacus, Andrei V. Gudkov, Carolyn R. Zelnick, Dot Chin, Randi Stern, Ilana Stancovski, Elior Peles, Noa Ben-Baruch, Hannan Farbstein, Ruth Lupu, Duanzhi Wen, Michael Sela, and Yosef Yarden
Cancer Res 1993 53: 5251-5261. [Abstract] [PDF]  

Development of Resistance to Hydroxyurea during Treatment of Human Myelogenous Leukemia K562 Cells with -Difluoromethylornithine as a Result of Coamplification of Genes for Ornithine Decarboxylase and Ribonucleotide Reductase R2 Subunit

Anders Ask, Lo Persson, Astrid Rehnholm, Lennart Frostesjö, Ingvar Holm, and Olle Heby
Cancer Res 1993 53: 5262-5268. [Abstract] [PDF]  

Absence of p53 Gene Mutations in Primary Neuroblastomas

Kyle Vogan, Mark Bernstein, Jean-Marie Leclerc, Linda Brisson, Josee Brossard, Garrett M. Brodeur, Jerry Pelletier, and Philippe Gros
Cancer Res 1993 53: 5269-5273. [Abstract] [PDF]  

The "Bystander Effect": Tumor Regression When a Fraction of the Tumor Mass Is Genetically Modified

Scott M. Freeman, Camille N. Abboud, Katharine A. Whartenby, Charles H. Packman, David S. Koeplin, Frederick L. Moolten, and George N. Abraham
Cancer Res 1993 53: 5274-5283. [Abstract] [PDF]  

Mutations of the p53 Gene Are Involved in Ewing's Sarcomas but not in Neuroblastomas

Hiroaki Komuro, Yasuhide Hayashi, Machiko Kawamura, Kenshi Hayashi, Yasuhiko Kaneko, Shigehiko Kamoshita, Ryoji Hanada, Keiko Yamamoto, Teruaki Hongo, Masao Yamada, and Yoshiaki Tsuchida
Cancer Res 1993 53: 5284-5288. [Abstract] [PDF]  

Tumor Biology:

Overexpression of Acidic and Basic Fibroblast Growth Factors in Human Pancreatic Cancer Correlates with Advanced Tumor Stage

Yoichiro Yamanaka, Helmut Friess, Markus Buchler, Hans G. Beger, Eiji Uchida, Masahiko Onda, Michael S. Kobrin, and Murray Korc
Cancer Res 1993 53: 5289-5296. [Abstract] [PDF]  

Basic Fibroblast Growth Factor Secreted by an Animal Tumor Is Detectable in Urine

Alexander D. Soutter, Mai Nguyen, Hiroyuki Watanabe, and Judah Folkman
Cancer Res 1993 53: 5297-5299. [Abstract] [PDF]  

Epidermal Growth Factor Receptor-mediated Autocrine and Paracrine Stimulation of Human Transitional Cell Carcinoma

Martin E. Gleave, Jer-Tsong Hsieh, Hsi-Chin Wu, Sung-Joon Hong, Haiyen E. Zhau, Paul D. Guthrie, and Leland W. K. Chung
Cancer Res 1993 53: 5300-5307. [Abstract] [PDF]  

Tumor Cell Heme Uptake Induces Ferritin Synthesis Resulting in Altered Oxidant Sensitivity: Possible Role in Chemotherapy Efficacy

Jaroslav Cermak, József Balla, Harry S. Jacob, György Balla, Helen Enright, Karl Nath, and Gregory M. Vercellotti
Cancer Res 1993 53: 5308-5313. [Abstract] [PDF]  

Apoptosis Induced in Burkitt's Lymphoma Cells via Gb3/CD77, a Glycolipid Antigen

Marianne Mangeney, Clifford A. Lingwood, Samir Taga, Bernard Caillou, Thomas Tursz, and Joëlle Wiels
Cancer Res 1993 53: 5314-5319. [Abstract] [PDF]  

Coexistence of Aneuploid Subclones within a Myeloma Cell Line That Exhibits Clonal Immunoglobulin Gene Rearrangement: Clinical Implications

Diane F. Jelinek, Gregory J. Ahmann, Philip R. Greipp, Syed M. Jalal, Jennifer J. Westendorf, Jerry A. Katzmann, Robert A. Kyle, and John A. Lust
Cancer Res 1993 53: 5320-5327. [Abstract] [PDF]  

Virology:

Malignant Transformation of Cutaneous Lesions in Renal Allograft Patients: A Role for Human Papillomavirus?

Karin J. Purdie, Connie J. Sexton, Charlotte M. Proby, Mary T. Glover, Anthony T. Williams, Jeremy N. Stables, and Irene M. Leigh
Cancer Res 1993 53: 5328-5333. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 5334-5336. [PDF]  

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