Advances in Brief:

Role of Tyrosine Phosphorylation in Radiation-induced Activation of c-jun Protooncogene in Human Lymphohematopoietic Precursor Cells

Heonjoo Park Chae, Lisa J. Jarvis, and Fatih M. Uckun
Cancer Res 1993 53: 447-451. [Abstract] [PDF]  

Screening for Germ Line p53 Mutations in Children with Malignant Tumors and a Family History of Cancer

L. Brugières, M. Gardes, C. Moutou, A. Chompret, V. Meresse, A. Martin, N. Poisson, F. Flamant, C. Bonaïti-Pellié, J. Lemerle, and J. Feunteun
Cancer Res 1993 53: 452-455. [Abstract] [PDF]  

Delayed-Type Hypersensitivity Reactions to Tumor-associated Antigens in Colon Carcinoma Patients Immunized with an Autologous Tumor Cell/Bacillus Calmette-Guérin Vaccine

Elisabeth Bloemena, Helen Gall, Janet H. Ransom, Nicholas Pomato, James H. Murray, Ebo Bos, Rik J. Scheper, Chris J. L. M. Meijer, Michael G. Hanna, Jr., and Jan B. Vermorken
Cancer Res 1993 53: 456-459. [Abstract] [PDF]  

DNA-Protein Cross-Links in Welders: Molecular Implications

Max Costa, Anatoly Zhitkovich, and Paolo Toniolo
Cancer Res 1993 53: 460-463. [Abstract] [PDF]  

Interleukin 6 Stimulates the Production of Immunoreactive Endothelin 1 in Human Breast Cancer Cells

Jun-ichi Yamashita, Michio Ogawa, Koichi Nomura, Shuichi Matsuo, Kazuo Inada, Shin-ichi Yamashita, Yasunari Nakashima, Tetsushi Saishoji, Sadamu Takano, and Shoji Fujita
Cancer Res 1993 53: 464-467. [Abstract] [PDF]  

p53 Abnormalities in Different Subtypes of Human Sarcomas

Å. Andreassen, T. Øyjord, E. Hovig, R. Holm, V. A. Flørenes, J. M. Nesland, O. Myklebost, J. Høie, Ø. S. Bruland, A-L. Børresen, and Ø. Fodstad
Cancer Res 1993 53: 468-471. [Abstract] [PDF]  

Time Course of Induction of Metabolism of all-trans-Retinoic Acid and the Up-Regulation of Cellular Retinoic Acid-binding Protein

Peter C. Adamson, John F. Boylan, Frank M. Balis, Robert F. Murphy, Karen A. Godwin, Lorraine J. Gudas, and David G. Poplack
Cancer Res 1993 53: 472-476. [Abstract] [PDF]  

Public Issues:

Trends in Program Project Grant Funding at the National Cancer Institute

Samuel Broder and Mary Cushing
Cancer Res 1993 53: 477-484. [PDF]  

Special Lecture:

Role of the BCR-ABL Oncogene in Human Leukemia: Fifteenth Richard and Hinda Rosenthal Foundation Award Lecture

Owen N. Witte
Cancer Res 1993 53: 485-489. [PDF]  

Biochemistry and Biophysics:

Induction of Topoisomerase I-mediated DNA Cleavage by a New Indolocarbazole, ED-110

Tomoko Yoshinari, Akihiro Yamada, Daisuke Uemura, Kazuhiro Nomura, Hiroharu Arakawa, Katsuhisa Kojiri, Eisaku Yoshida, Hiroyuki Suda, and Akira Okura
Cancer Res 1993 53: 490-494. [Abstract] [PDF]  

Carcinogenesis:

Identification of Cellular Defect in UVS1, a UV-sensitive Chinese Hamster Ovary Mutant Cell Line

Masayuki Numata, Hiroaki Hata, Tadahiro Shiomi, Tsukasa Matsunaga, Toshio Mori, Osamu Nikaido, Akira Yasui, and Atsushi Oikawa
Cancer Res 1993 53: 495-499. [Abstract] [PDF]  

Clonal Analysis of the Expression of Multiple Transformation Phenotypes and Tumorigenicity by Morphologically Transformed 10T1/2 Cells

Gary J. Smith, William N. Bell, and Joe W. Grisham
Cancer Res 1993 53: 500-508. [Abstract] [PDF]  

Metabolic Activation of N-Hydroxy-2-aminofluorene and N-Hydroxy-2-acetylaminofluorene by Monomorphic N-Acetyltransferase (NAT1) and Polymorphic N-Acetyltransferase (NAT2) in Colon Cytosols of Syrian Hamsters Congenic at the NAT2 Locus

David W. Hein, Mark A. Doll, Kevin Gray, Timothy D. Rustan, and Ronald J. Ferguson
Cancer Res 1993 53: 509-514. [Abstract] [PDF]  

Transformation-induced Alterations in the Regulation of Tyrosine Aminotransferase Expression in Fetal Rat Hepatocytes: Changes in Hormone Inducibility and the DNase-hypersensitive Site

George C. T. Yeoh and Christopher J. Fisher
Cancer Res 1993 53: 515-522. [Abstract] [PDF]  

Clinical Investigations:

Phase I and Pharmacokinetic Study of Taxotere (RP 56976) Administered as a 24-Hour Infusion

D. Bissett, A. Setanoians, J. Cassidy, M. A. Graham, G. A. Chadwick, P. Wilson, V. Auzannet, N. Le Bail, S. B. Kaye, and D. J. Kerr
Cancer Res 1993 53: 523-527. [Abstract] [PDF]  

Endocrinology:

Selective Increase in Type II Estrogen-binding Sites in the Dysplastic Dorsolateral Prostates of Noble Rats

Shuk-mei Ho and Margaret Yu
Cancer Res 1993 53: 528-532. [Abstract] [PDF]  

Inhibition of Angiogenesis by Antiestrogens

A. Gagliardi and D. C. Collins
Cancer Res 1993 53: 533-535. [Abstract] [PDF]  

Epidemiology:

Vegetables, Fruit, and Lung Cancer in the Iowa Women's Health Study

Kristi A. Steinmetz, John D. Potter, and Aaron R. Folsom
Cancer Res 1993 53: 536-543. [Abstract] [PDF]  

Experimental Therapeutics:

Reduced Glutathione Protects against Cisplatin-induced Neurotoxicity in Rats

Frank P. T. Hamers, Jan H. Brakkee, Ennio Cavalletti, Michele Tedeschi, Laura Marmonti, Gabriella Pezzoni, Jan P. Neijt, and Willem H. Gispen
Cancer Res 1993 53: 544-549. [Abstract] [PDF]  

Characterization of Experimental Mitoxantrone Cardiotoxicity and Its Partial Inhibition by ICRF-187 in Cultured Neonatal Rat Heart Cells

N. G. Shipp, Robert T. Dorr, David S. Alberts, Brenda V. Dawson, and Mary Hendrix
Cancer Res 1993 53: 550-556. [Abstract] [PDF]  

O-Phospho-L-tyrosine Inhibits Cellular Growth by Activating Protein Tyrosine Phosphatases

Shrikant Mishra and Anne W. Hamburger
Cancer Res 1993 53: 557-563. [Abstract] [PDF]  

Nitric Oxide/Nucleophile Complexes Inhibit the in Vitro Proliferation of A375 Melanoma Cells via Nitric Oxide Release

Chris M. Maragos, Ji Ming Wang, Joseph A. Hrabie, Joost J. Oppenheim, and Larry K. Keefer
Cancer Res 1993 53: 564-568. [Abstract] [PDF]  

Combined Interleukin 1ß/Interleukin 2 Treatment in Mice: Synergistic Myelostimulatory Activity and Protection against Cyclophosphamide-induced Myelosuppression

Enrico Proietti, Elena Tritarelli, Lucia Gabriele, Ugo Testa, Giampaolo Greco, Elvira Pelosi, Marco Gabbianelli, Filippo Belardelli, and Cesare Peschle
Cancer Res 1993 53: 569-576. [Abstract] [PDF]  

Antisense DNA Inhibition of Tumor Growth Induced by c-Ha-ras Oncogene in Nude Mice

Gary D. Gray, Olga M. Hernandez, Denise Hebel, Malcolm Root, Julio M. Pow-Sang, and Eric Wickstrom
Cancer Res 1993 53: 577-580. [Abstract] [PDF]  

Antitumor Activity of N¹,N¹¹-Bis(ethyl)norspermine against Human Melanoma Xenografts and Possible Biochemical Correlates of Drug Action

Carl W. Porter, Ralph J. Bernacki, John Miller, and Raymond J. Bergeron
Cancer Res 1993 53: 581-586. [Abstract] [PDF]  

Markedly Improved Efficacy of Edatrexate Compared to Methotrexate in a High-Dose Regimen with Leucovorin Rescue against Metastatic Murine Solid Tumors

F. M. Sirotnak, G. M. Otter, and F. A. Schmid
Cancer Res 1993 53: 587-591. [Abstract] [PDF]  

Immunology:

Molecular Basis of Complement Resistance of Human Melanoma Cells Expressing the C3-cleaving Membrane Protease p65

Markus W. Ollert, Joseph V. Kadlec, Eugene C. Petrella, Reinhard Bredehorst, and Carl-Wilhelm Vogel
Cancer Res 1993 53: 592-599. [Abstract] [PDF]  

Improved Radioimmunotherapeutic Efficacy of an Anticarcinoma Monoclonal Antibody (¹³¹I-CC49) When Given in Combination with -Interferon

John W. Greiner, Claudio Dansky Ullmann, Carol Nieroda, Chen-Feng Qi, Diane Eggensperger, Shinya Shimada, Seth M. Steinberg, and Jeffrey Schlom
Cancer Res 1993 53: 600-608. [Abstract] [PDF]  

Molecular Biology and Genetics:

Hypersensitivity of Human Lymphocytes to UV-B and Solar Irradiation

Colin F. Arlett, Jillian E. Lowe, Susan A. Harcourt, Alastair P. W. Waugh, Jane Cole, Leendert Roza, Brian L. Diffey, Toshio Mori, Osamu Nikaido, and Michael H. L. Green
Cancer Res 1993 53: 609-614. [Abstract] [PDF]  

Tumor Necrosis Factor and Interleukin 1 Induce Anchorage Independence in v-jun Transgenic Murine Cells

Luc Vanhamme, Glenn M. Marshall, Andre C. Schuh, Martin L. Breitman, and Peter K. Vogt
Cancer Res 1993 53: 615-621. [Abstract] [PDF]  

Characterization of Sarcoma Cell Lines from v-jun Transgenic Mice

Glenn M. Marshall and Luc Vanhamme
Cancer Res 1993 53: 622-626. [Abstract] [PDF]  

Tumor Biology:

Differential Isolation of Normal Luminal Mammary Epithelial Cells and Breast Cancer Cells from Primary and Metastatic Sites Using Selective Media

Stephen P. Ethier, Michael L. Mahacek, William J. Gullick, Thomas S. Frank, and Barbara L. Weber
Cancer Res 1993 53: 627-635. [Abstract] [PDF]  

Growth Inhibition of a Human Colorectal Carcinoma Cell Line by Interleukin 1 Is Associated with Enhanced Expression of -Interferon Receptors

Arthur B. Raitano and Murray Korc
Cancer Res 1993 53: 636-640. [Abstract] [PDF]  

Heterogeneity of Mucin Gene Expression in Normal and Neoplastic Tissues

Samuel B. Ho, Gloria A. Niehans, Carolyn Lyftogt, Pei Sha Yan, David L. Cherwitz, Elizabeth T. Gum, Rajvir Dahiya, and Young S. Kim
Cancer Res 1993 53: 641-651. [Abstract] [PDF]  

Suramin Inhibits Growth and Yet Promotes Insulin-like Growth Factor II Expression in HepG2 Cells

Andrea Kraft, Lola M. Reid, and Isabel Zvibel
Cancer Res 1993 53: 652-657. [Abstract] [PDF]  

Distribution of Colon Cancer Cells Permanently Labeled by Lectin-mediated Endocytosis of a Trap Label

Christian Rushfeldt and Bård Smedsrød
Cancer Res 1993 53: 658-662. [Abstract] [PDF]  

Morphological and Functional Properties of TM Preneoplastic Mammary Outgrowths

Daniel Medina, Frances S. Kittrell, Yong-Jian Liu, and Marlene Schwartz
Cancer Res 1993 53: 663-667. [Abstract] [PDF]  

Growth Factor Dependency and Gene Expression in Preneoplastic Mouse Mammary Epithelial Cells

Daniel Medina, Frances S. Kittrell, Carol J. Oborn, and Marlene Schwartz
Cancer Res 1993 53: 668-674. [Abstract] [PDF]  

Functional Expression of Interleukin 2 Receptor in a Human Factor-dependent Megakaryoblastic Leukemia Cell Line: Evidence That Granulocyte-Macrophage Colony-stimulating Factor Inhibits Interleukin 2 Binding to Its Receptor

Yuzuru Kanakura, Hiroyuki Sugahara, Hideki Mitsui, Hirokazu Ikeda, Takuma Furitsu, Hirosuke Yagura, Hitoshi Kitayama, Yoshio Kanayama, and Yuji Matsuzawa
Cancer Res 1993 53: 675-680. [Abstract] [PDF]  

Chromosomes 8, 12, and 17 Copy Number in Astler-Coller Stage C Colon Cancer in Relation to Proliferative Activity and DNA Ploidy

Melissa G. Steiner, Seth P. Harlow, Edoardo Colombo, and Kenneth D. Bauer
Cancer Res 1993 53: 681-686. [Abstract] [PDF]  

Milky Spots as the Implantation Site for Malignant Cells in Peritoneal Dissemination in Mice

Akeo Hagiwara, Toshio Takahashi, Kiyoshi Sawai, Hiroki Taniguchi, Masataka Shimotsuma, Shinji Okano, Chouhei Sakakura, Hiroyuki Tsujimoto, Kimihiko Osaki, Sadayuki Sasaki, and Morio Shirasu
Cancer Res 1993 53: 687-692. [Abstract] [PDF]  

Melanoma-mediated Dissolution of Extracellular Matrix: Contribution of Urokinase-dependent and Metalloproteinase-dependent Proteolytic Pathways

Anthony M. P. Montgomery, Yves A. De Clerck, Keith E. Langley, Ralph A. Reisfeld, and Barbara M. Mueller
Cancer Res 1993 53: 693-700. [Abstract] [PDF]  

Adhesion of Metastatic, ras-transformed NIH 3T3 Cells to Osteopontin, Fibronectin, and Laminin

Ann F. Chambers, Charulata Hota, and Charles W. Prince
Cancer Res 1993 53: 701-706. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 707-709. [PDF]  

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