Advances in Brief:

A Rapid Colorimetric in Situ Messenger RNA Hybridization Technique for Analysis of Epidermal Growth Factor Receptor in Paraffin-embedded Surgical Specimens of Human Colon Carcinomas

Robert Radinsky, Corazon D. Bucana, Lee M. Ellis, Ricardo Sanchez, Karen R. Cleary, David J. Brigati, and Isaiah J. Fidler
Cancer Res 1993 53: 937-943. [Abstract] [PDF]  

Evidence for the Involvement of a Bis-Diol-Epoxide in the Metabolic Activation of Dibenz[a,h]anthracene to DNA-binding Species in Mouse Skin

Paul L. Carmichael, Karl L. Platt, Meadhbh Ní Shé, Sophie Lecoq, Franz Oesch, David H. Phillips, and Philip L. Grover
Cancer Res 1993 53: 944-948. [Abstract] [PDF]  

Transfection of Interleukin 2 Gene into Human Melanoma Cells Augments Cellular Immune Response

Akihiko Uchiyama, Dave S. B. Hoon, Takashi Morisaki, Yasufumi Kaneda, Dale H. Yuzuki, and Donald L. Morton
Cancer Res 1993 53: 949-952. [Abstract] [PDF]  

Frequent c-Ki-ras Oncogene Activation in Mucous Cell Hyperplasias of Pancreas Suffering from Chronic Inflammation

Akio Yanagisawa, Keiko Ohtake, Kazuhiko Ohashi, Masharu Hori, Tomoyuki Kitagawa, Haruo Sugano, and Yo Kato
Cancer Res 1993 53: 953-956. [Abstract] [PDF]  

Turcot's Syndrome of Glioma and Polyposis Occurs in the Absence of Germ Line Mutations of Exons 5 to 9 of the p53 Gene

Tetsuro Kikuchi, Sandra A. Rempel, Hans-Peter Rutz, Nicolas de Tribolet, Lois Mulligan, Webster K. Cavenee, Serge Jothy, Lam Leduy, and Erwin G. Van Meir
Cancer Res 1993 53: 957-961. [Abstract] [PDF]  

In Vitro and in Vivo Targeting of Gene Expression to Melanoma Cells

Richard G. Vile and Ian R. Hart
Cancer Res 1993 53: 962-967. [Abstract] [PDF]  

Biochemistry and Biophysics:

Reversal of Cytochrome P-4501A1 and P-450-EF Expression in MCA-C3H/10T1/2 Cell-derived Tumors as Compared to Cultured Cells

Maro Christou, Ingegerd M. Keith, Xin Shen, Mary E. Schroeder, and Colin R. Jefcoate
Cancer Res 1993 53: 968-976. [Abstract] [PDF]  

Functional Imaging of Multidrug-resistant P-Glycoprotein with an Organotechnetium Complex

David Piwnica-Worms, Mary L. Chiu, Mark Budding, James F. Kronauge, Robert A. Kramer, and James M. Croop
Cancer Res 1993 53: 977-984. [Abstract] [PDF]  

Carcinogenesis:

Development of Tumorigenicity in Simian Virus 40-immortalized Human Bronchial Epithelial Cell Lines

Roger R. Reddel, Simone E. Salghetti, James C. Willey, Yasushi Ohnuki, Yang Ke, Brenda I. Gerwin, John F. Lechner, and Curtis C. Harris
Cancer Res 1993 53: 985-991. [Abstract] [PDF]  

Hyperphosphorylation of Cytokeratins by Okadaic Acid Class Tumor Promoters in Primary Human Keratinocytes

Jun Yatsunami, Atsumasa Komori, Tetsuya Ohta, Masami Suganuma, Stuart H. Yuspa, and Hirota Fujiki
Cancer Res 1993 53: 992-996. [Abstract] [PDF]  

Specificity of Bischloroethylnitrosourea-induced Mutation in a Chinese Hamster Ovary Cell Line Transformed to Express Human O⁶-Alkylguanine-DNA Alkyltransferase

Dana T. Minnick, Stanton L. Gerson, Luba L. Dumenco, Martina L. Veigl, and W. David Sedwick
Cancer Res 1993 53: 997-1003. [Abstract] [PDF]  

Genotype and Phenotype of Glutathione S-Transferase Class µ Isoenzymes µ and in Lung Cancer Patients and Controls

Jürgen Brockmöller, Reinhold Kerb, Nikolaos Drakoulis, Manfred Nitz, and Ivar Roots
Cancer Res 1993 53: 1004-1011. [Abstract] [PDF]  

Absence of Synergistic Effects on Tumor Promotion in CD-1 Mouse Skin by Simultaneous Applications of Two Different Types of Tumor Promoters, Okadaic Acid and Teleocidin

Masami Suganuma, Jun Yatsunami, Seiji Yoshizawa, Sachiko Okabe, and Hirota Fujiki
Cancer Res 1993 53: 1012-1016. [Abstract] [PDF]  

Sulfotransferase-mediated Activation of 4-Hydroxy- and 3,4-Dihydroxy-3,4-dihydrocyclopenta[c,d]pyrene, Major Metabolites of Cyclopenta[c,d]pyrene

Young-Joon Surh, Hoonjeong Kwon, and Steven R. Tannenbaum
Cancer Res 1993 53: 1017-1022. [Abstract] [PDF]  

Benzene and Its Phenolic Metabolites Produce Oxidative DNA Damage in HL60 Cells in Vitro and in the Bone Marrow in Vivo

Prema Kolachana, Vangala V. Subrahmanyam, Kathleen B. Meyer, Luoping Zhang, and Martyn T. Smith
Cancer Res 1993 53: 1023-1026. [Abstract] [PDF]  

Clinical Investigations:

Immunocytological Detection of Bone Marrow Micrometastasis in Operable Non-Small Cell Lung Cancer

K. Pantel, J. R. Izbicki, M. Angstwurm, S. Braun, B. Passlick, O. Karg, O. Thetter, and G. Riethmüller
Cancer Res 1993 53: 1027-1031. [Abstract] [PDF]  

Pediatric Phase I Trial and Pharmacokinetic Study of Topotecan Administered as a 24-Hour Continuous Infusion

Susan M. Blaney, Frank M. Balis, Diane E. Cole, Catherine Craig, Joel M. Reid, Matthew M. Ames, Mark Krailo, Gregory Reaman, Denman Hammond, and David G. Poplack
Cancer Res 1993 53: 1032-1036. [Abstract] [PDF]  

Phase I and Pharmacokinetic Study of Taxotere (RP 56976; NSC 628503) Given as a Short Intravenous Infusion

Jean-Marc Extra, Frédérique Rousseau, René Bruno, Michel Clavel, Nathalie Le Bail, and Michel Marty
Cancer Res 1993 53: 1037-1042. [Abstract] [PDF]  

Clinical Observations on Adoptive Immunotherapy with Vaccine-primed T-Lymphocytes Secondarily Sensitized to Tumor in Vitro

Alfred E. Chang, Hirohisa Yoshizawa, Keisuke Sakai, Mark J. Cameron, Vernon K. Sondak, and Suyu Shu
Cancer Res 1993 53: 1043-1050. [Abstract] [PDF]  

Endocrinology:

Growth Factor Regulation of Gene Expression in the Human Prostatic Carcinoma Cell Line LNCaP

Pirkko Henttu and Pirkko Vihko
Cancer Res 1993 53: 1051-1058. [Abstract] [PDF]  

Genetic Susceptibility for C19 Androgen Induction of Ovarian Granulosa Cell Tumorigenesis in SWXJ Strains of Mice

Barbara J. Tennent, Kathryn L. Shultz, and Wesley G. Beamer
Cancer Res 1993 53: 1059-1063. [Abstract] [PDF]  

Experimental Therapeutics:

Topoisomerase II as a Target of VM-26 and 4'-(9-Acridinylamino)methanesulfon-m-aniside in Atypical Multidrug Resistant Human Small Cell Lung Carcinoma Cells

Steven de Jong, Alfred J. Kooistra, Elisabeth G.E. de Vries, Nanno H. Mulder, and Jan G. Zijlstra
Cancer Res 1993 53: 1064-1071. [Abstract] [PDF]  

Mitochondrial Cytochrome c Oxidase as a Target Site for Daunomycin in K-562 Cells and Heart Tissue

Lefkothea C. Papadopoulou and Asterios S. Tsiftsoglou
Cancer Res 1993 53: 1072-1078. [Abstract] [PDF]  

Combination Cytotoxic Effects of cis-Diamminedichloroplatinum(II) and 5-Fluorouracil with and without Leucovorin against Human Non-Small Cell Lung Cancer Cell Lines

Chun-Ming Tsai, Shu-Huei Hsiao, Carolin M. Frey, Kuo-Ting Chang, Reury-Perng Perng, Adi F. Gazdar, and Barrnett S. Kramer
Cancer Res 1993 53: 1079-1084. [Abstract] [PDF]  

Enhanced Expression of the DNA Topoisomerase II Gene in Response to Heat Shock Stress in Human Epidermoid Cancer KB Cells

Ken-ichi Matsuo, Kimitoshi Kohno, Seiji Sato, Takeshi Uchiumi, Hideyuki Tanimura, Yuji Yamada, and Michihiko Kuwano
Cancer Res 1993 53: 1085-1090. [Abstract] [PDF]  

Synergistic Antitumor Activity of Cisplatin and Interleukin 1 in Sensitive and Resistant Solid Tumors

Paul G. Braunschweiger, Vathsala S. Basrur, Octavio Santos, Arnold M. Markoe, Pavel V. Houdek, and James G. Schwade
Cancer Res 1993 53: 1091-1097. [Abstract] [PDF]  

Methylthioadenosine Phosphorylase Deficiency in Human Non-Small Cell Lung Cancers

Tsutomu Nobori, Istvan Szinai, Diane Amox, Barbara Parker, Olufunmilayo I. Olopade, Dorothy L. Buchhagen, and Dennis A. Carson
Cancer Res 1993 53: 1098-1101. [Abstract] [PDF]  

Inhibition of Growth of Prostatic Cancer Cell Lines by Peptide Analogues of Insulin-like Growth Factor 1

Zbigniew Pietrzkowski, Grant Mulholland, Leonard Gomella, Bradford A. Jameson, Dorothee Wernicke, and Renato Baserga
Cancer Res 1993 53: 1102-1106. [Abstract] [PDF]  

₁-Interferon Gene Transfer into Metastatic Friend Leukemia Cells Abrogated Tumorigenicity in Immunocompetent Mice: Antitumor Therapy by Means of Interferon-producing Cells

Maria Ferrantini, Enrico Proietti, Laura Santodonato, Lucia Gabriele, Manuela Peretti, Ivan Plavec, François Meyer, Thomas Kaido, Ion Gresser, and Filippo Belardelli
Cancer Res 1993 53: 1107-1112. [Abstract] [PDF]  

Immunology:

Protection against Experimental Cerebral Metastases of Murine Melanoma B16 by Active Immunization

Ludger Staib, William Harel, and Malcolm S. Mitchell
Cancer Res 1993 53: 1113-1121. [Abstract] [PDF]  

AgSK1, a Novel Carcinoma Associated Antigen

H. R. Chang, K. Koda, Steven Chang, and S. Baird
Cancer Res 1993 53: 1122-1127. [Abstract] [PDF]  

Molecular Biology and Genetics:

Differential Effect of Ionizing Radiation on the Expression of Cyclin A and Cyclin B in Hela Cells

Ruth J. Muschel, Hong Bing Zhang, and W. Gillies McKenna
Cancer Res 1993 53: 1128-1135. [Abstract] [PDF]  

Isolation of the Complementary DNA Encoding a Mouse Heparin-binding Growth Factor Receptor with the Use of a Unique Kinase Insert Sequence

Osamu Katoh, Yutaka Hattori, Hiroki Sasaki, Hiromi Sakamoto, Kiyohide Fujimoto, Takuma Fujii, Takashi Sugimura, and Masaaki Terada
Cancer Res 1993 53: 1136-1141. [Abstract] [PDF]  

Dimethyl Sulfoxide Inhibits the Binding of Granulocyte/Macrophage Colony-stimulating Factor and Insulin to Their Receptors on Human Leukemia Cells

Edward L. Schwartz, Helena Chamberlin, Pinjai Ravichander, and John A. Whitbread
Cancer Res 1993 53: 1142-1148. [Abstract] [PDF]  

Mutagenic Processing of Ethylation Damage in Mammalian Cells: The Use of Methoxyamine to Study Apurinic/Apyrimidinic Site-induced Mutagenesis

Paola Fortini, Angelo Calcagnile, Harry Vrieling, Albert A. van Zeeland, Margherita Bignami, and Eugenia Dogliotti
Cancer Res 1993 53: 1149-1155. [Abstract] [PDF]  

Induced Megakaryocytic Maturation of the Human Leukemia Cell Line UT-7 Results in Down-Modulation of Erythropoietin Receptor Gene Expression

Norio Komatsu and Hiroyoshi Fujita
Cancer Res 1993 53: 1156-1161. [Abstract] [PDF]  

Distinct Pattern of p53 Mutations in Bladder Cancer: Relationship to Tobacco Usage

Charles H. Spruck, III, William M. Rideout, III, Aria F. Olumi, Petra F. Ohneseit, Allen S. Yang, Yvonne C. Tsai, Peter W. Nichols, Thomas Horn, Gregers G. Hermann, Kenneth Steven, Ronald K. Ross, Mimi C. Yu, and Peter A. Jones
Cancer Res 1993 53: 1162-1166. [Abstract] [PDF]  

Genetic Analysis of in Vitro Progression of Human Papillomavirus-transfected Human Cervical Cells

Tzer-Ming Chen, Gene Pecoraro, and Vittorio Defendi
Cancer Res 1993 53: 1167-1171. [Abstract] [PDF]  

Evidence for the Presence of Two Tumor Suppressor Genes on Chromosome 8p for Colorectal Carcinoma

Yoshiyuki Fujiwara, Mitsuru Emi, Hiroyuki Ohata, Yo Kato, Toshifusa Nakajima, Takesada Mori, and Yusuke Nakamura
Cancer Res 1993 53: 1172-1174. [Abstract] [PDF]  

Tumor Biology:

Peripherin, a Neuronal Intermediate Protein, Is Stably Expressed by Neuroendocrine Carcinomas of the Skin, Their Xenograft on Nude Mice, and the Corresponding Primary Cultures

C. Baudoin, G. Meneguzzi, M. M. Portier, M. Demarchez, F. Bernerd, A. Pisani, and J. P. Ortonne
Cancer Res 1993 53: 1175-1181. [Abstract] [PDF]  

Morphological and Biological Modifications Induced in a Rat Pancreatic Acinar Cancer Cell Line (AR4-2J) by Unscheduled Expression of Basic Fibroblast Growth Factors

Agnès Estival, Dominique Louvel, Bettina Couderc, Hervé Prats, Etienne Hollande, Nicole Vaysse, and François Clémente
Cancer Res 1993 53: 1182-1187. [Abstract] [PDF]  

Calories, Parity, and Prolactin Influence Mammary Epithelial Kinetics and Differentiation and Alter Mouse Mammary Tumor Risk

Robert W. Engelman, Noorbibi K. Day, and Robert A. Good
Cancer Res 1993 53: 1188-1194. [Abstract] [PDF]  

Purification and Characterization of a Novel Cytotoxic Protein from Transformed Fibroblasts

Stanley Zucker, Betty I. DiMassimo, Rita M. Lysik, and Sergey Lyubsky
Cancer Res 1993 53: 1195-1203. [Abstract] [PDF]  

Nude Mouse Metastatic Models of Human Stomach Cancer Constructed Using Orthotopic Implantation of Histologically Intact Tissue

Toshiharu Furukawa, Xinyu Fu, Tetsuro Kubota, Masahiko Watanabe, Masaki Kitajima, and Robert M. Hoffman
Cancer Res 1993 53: 1204-1208. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 1209-1211. [PDF]  

Announcements:

Calendar Of Events

Cancer Res 1993 53: 1211 [PDF]  

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