Advances in Brief:

Persistent Inhibition of DNA Synthesis in Irradiated Rat Embryo Fibroblasts Expressing the Oncogenes H-ras plus v-myc Derives from Inhibition of Replicon Initiation and Is Mitigated by Staurosporine

Ya Wang, Nge Cheong, and George Iliakis
Cancer Res 1993 53: 1213-1217. [Abstract] [PDF]  

A Deletion Unit on Chromosome 17q in Epithelial Ovarian Tumors Distal to the Familial Breast/Ovarian Cancer Locus

I. J. Jacobs, S. A. Smith, R. W. Wiseman, P. A. Futreal, T. Harrington, R. J. Osborne, V. Leech, A. Molyneux, A. Berchuck, B. A. J. Ponder, and R. C. Bast, Jr.
Cancer Res 1993 53: 1218-1221. [Abstract] [PDF]  

Heterotransplantation of Early B-Lineage Acute Lymphoblastic Leukemia Using a Solubilized Attachment Matrix (Matrigel)

Katy Sterling-Levis, Les White, Annette E. Trickett, Cilinia Gramacho, Sally M. Pittman, and Vivienne Tobias
Cancer Res 1993 53: 1222-1225. [Abstract] [PDF]  

Lipid Hydroperoxides Greatly Increase the Rate of Oxidative Catabolism of All-trans-Retinoic Acid by Human Cell Culture Microsomes Genetically Enriched in Specified Cytochrome P-450 Isoforms

Josephia F. Muindi and Charles W. Young
Cancer Res 1993 53: 1226-1229. [Abstract] [PDF]  

Preliminary Mapping of the Deleted Region of Chromosome 9 in Bladder Cancer

Paul Cairns, Margaret E. Shaw, and Margaret A. Knowles
Cancer Res 1993 53: 1230-1232. [Abstract] [PDF]  

Biochemistry and Biophysics:

Regulation of Fibroblast Hepatocyte Growth Factor/Scatter Factor Expression by Human Breast Carcinoma Cell Lines and Peptide Growth Factors

Stephen P. Seslar, Toshikazu Nakamura, and Stephen W. Byers
Cancer Res 1993 53: 1233-1238. [Abstract] [PDF]  

Cell Killing and Chromosomal Aberrations Induced in Chinese Hamster Ovary Cells by Treating with Cisplatin at 41.5°C during G₁ or Late S Phase

Girija Krishnaswamy and William C. Dewey
Cancer Res 1993 53: 1239-1243. [Abstract] [PDF]  

Characterization of the DNA Double Strand Break Repair Defect in scid Mice

Carolyn Chang, Kim A. Biedermann, Mauro Mezzina, and J. Martin Brown
Cancer Res 1993 53: 1244-1248. [Abstract] [PDF]  

Fluence Rate Effects in Photodynamic Therapy of Multicell Tumor Spheroids

Thomas H. Foster, Donna F. Hartley, Michael G. Nichols, and Russell Hilf
Cancer Res 1993 53: 1249-1254. [Abstract] [PDF]  

Carcinogenesis:

Inhibition of Tumor Promoter-mediated Processes in Mouse Skin and Bovine Lens by Caffeic Acid Phenethyl Ester

Krystyna Frenkel, Huachen Wei, Ramesh Bhimani, Jingjing Ye, Jose A. Zadunaisky, Mou-Tuan Huang, Thomas Ferraro, Allan H. Conney, and Dezider Grunberger
Cancer Res 1993 53: 1255-1261. [Abstract] [PDF]  

The Two Major CD44 Proteins Expressed on a Metastatic Rat Tumor Cell Line Are Derived from Different Splice Variants: Each One Individually Suffices to Confer Metastatic Behavior

Wolfgang Rudy, Martin Hofmann, Reinhard Schwartz-Albiez, Margot Zöller, Karl-Heinz Heider, Helmut Ponta, and Peter Herrlich
Cancer Res 1993 53: 1262-1268. [Abstract] [PDF]  

Modification of DNA Bases in Chromatin of Intact Target Human Cells by Activated Human Polymorphonuclear Leukocytes

Miral Dizdaroglu, Ryszard Olinski, James H. Doroshow, and Steven A. Akman
Cancer Res 1993 53: 1269-1272. [Abstract] [PDF]  

Sequence Specificity in the Interaction of the Four Stereoisomeric Benzo[c]phenanthrene Dihydrodiol Epoxides with the supF Gene

Helen Ross, C. Anita, H. Bigger, Haruhiko Yagi, Donald M. Jerina, and Anthony Dipple
Cancer Res 1993 53: 1273-1277. [Abstract] [PDF]  

Detection of Aflatoxin B₁-DNA Adducts in Human Placenta and Cord Blood

Ling-Ling Hsieh and Tsang-Tang Hsieh
Cancer Res 1993 53: 1278-1280. [Abstract] [PDF]  

Clinical Investigations:

A New Family of Heparin-binding Growth/Differentiation Factors: Increased Midkine Expression in Wilms' Tumor and Other Human Carcinomas

Jun-ichiro Tsutsui, Kenji Kadomatsu, Shyuichiro Matsubara, Akira Nakagawara, Masahiro Hamanoue, Sonshin Takao, Hisaaki Shimazu, Yoshitada Ohi, and Takashi Muramatsu
Cancer Res 1993 53: 1281-1285. [Abstract] [PDF]  

A Direct Comparison of Immunological and Clinical Effects of Interleukin 2 with and without Interferon- in Humans

Joan H. Schiller, Jacquelyn Hank, Barry Storer, Agnes A. Borchert, Karen Huseby Moore, Mark Albertini, Robin Bechhofer, Osvaldo Wesley, Raymond R. Brown, Ann Mrowca Bastin, and Paul M. Sondel
Cancer Res 1993 53: 1286-1292. [Abstract] [PDF]  

Phase I Clinical and Pharmacological Study of Iododeoxyuridine and Bleomycin in Patients with Advanced Cancer

Richard L. Schilsky, Linda Janisch, Frances Berezin, Rosemarie Mick, Nicholas J. Vogelzang, and Mark J. Ratain
Cancer Res 1993 53: 1293-1296. [Abstract] [PDF]  

Autologous Stem Cell Transplantation: Sequential Production of Hematopoietic Cytokines Underlying Granulocyte Recovery

G. Baiocchi, G. Scambia, P. Benedetti, G. Menichella, U. Testa, L. Pierelli, R. Martucci, M. L. Foddai, B. Bizzi, S. Mancuso, and C. Peschle
Cancer Res 1993 53: 1297-1303. [Abstract] [PDF]  

Endocrinology:

Androgen-induced Inhibition of Cell Proliferation in an Androgen-insensitive Prostate Cancer Cell Line (PC-3) Transfected with a Human Androgen Receptor Complementary DNA

Shixing Yuan, John Trachtenberg, Gordon B. Mills, Theodore J. Brown, Fong Xu, and Armand Keating
Cancer Res 1993 53: 1304-1311. [Abstract] [PDF]  

Progesterone Receptor Expression in Meningiomas

Rona S. Carroll, Danuta Glowacka, Kathleen Dashner, and Peter M. Black
Cancer Res 1993 53: 1312-1316. [Abstract] [PDF]  

Epidemiology:

Precancerous Gastric Lesions in a Population at High Risk of Stomach Cancer

Wei-cheng You, William J. Blot, Ji-you Li, Yun-sheng Chang, Mao-lin Jin, Robert Kneller, Lian Zhang, Zhong-xiang Han, Xiang-rui Zeng, Wei-dong Liu, Lei Zhao, Pelayo Correa, Joseph F. Fraumeni, Jr., and Guang-wei Xu
Cancer Res 1993 53: 1317-1321. [Abstract] [PDF]  

Aspirin Use and Risk of Fatal Cancer

Michael J. Thun, Mohan M. Namboodiri, Eugenia E. Calle, W. Dana Flanders, and Clark W. Heath, Jr.
Cancer Res 1993 53: 1322-1327. [Abstract] [PDF]  

Experimental Therapeutics:

Genistein Arrests Cell Cycle Progression at G₂-M

Yoshizumi Matsukawa, Nobuyuki Marui, Toshiyuki Sakai, Yoshiko Satomi, Mitsunori Yoshida, Katsuhiko Matsumoto, Hoyoku Nishino, and Akira Aoike
Cancer Res 1993 53: 1328-1331. [Abstract] [PDF]  

A New Mammalian DNA Topoisomerase I Poison Hoechst 33342: Cytotoxicity and Drug Resistance in Human Cell Cultures

Allan Y. Chen, Chiang Yu, Annette Bodley, Lynn F. Peng, and Leroy F. Liu
Cancer Res 1993 53: 1332-1337. [Abstract] [PDF]  

Increased NAD(P)H:(Quinone-Acceptor)Oxidoreductase Activity Is Associated with Density-dependent Growth Inhibition of Normal but not Transformed Cells

John J. Schlager, Bryan J. Hoerl, John Riebow, David P. Scott, Pam Gasdaska, Robert E. Scott, and Garth Powis
Cancer Res 1993 53: 1338-1342. [Abstract] [PDF]  

Scytophycins, Novel Microfilament-depolymerizing Agents Which Circumvent P-Glycoprotein-mediated Multidrug Resistance

Charles D. Smith, Shmuel Carmeli, Richard E. Moore, and Gregory M. L. Patterson
Cancer Res 1993 53: 1343-1347. [Abstract] [PDF]  

Efficacy of Transferrin Receptor-targeted Immunotoxins in Brain Tumor Cell Lines and Pediatric Brain Tumors

Lori A. Martell, Alka Agrawal, Donald A. Ross, and Karin M. Muraszko
Cancer Res 1993 53: 1348-1353. [Abstract] [PDF]  

Multidrug Resistance Is a Component of V79 Cell Resistance to the Alkylating Agent Adozelesin

Bijoy K. Bhuyan, Kathy S. Smith, Robert C. Kelly, Earl G. Adams, Irene Abraham, and Kathleen E. Sampson
Cancer Res 1993 53: 1354-1359. [Abstract] [PDF]  

Anti-B4-blocked Ricin Immunotoxin Shows Therapeutic Efficacy in Four Different SCID Mouse Tumor Models

Sudhir A. Shah, Patricia M. Halloran, Cynthia A. Ferris, Beth A. Levine, Lizabeth A. Bourret, Victor S. Goldmacher, and Walter A. Blättler
Cancer Res 1993 53: 1360-1367. [Abstract] [PDF]  

Taxol, Radiation, and Oncogenic Transformation

Tom K. Hei and Eric J. Hall
Cancer Res 1993 53: 1368-1372. [Abstract] [PDF]  

Single-Strand Conformational Polymorphism Analysis of the M_r 170,000 Isozyme of DNA Topoisomerase II in Human Tumor Cells

Mary K. Danks, Michael R. Warmoth, Ellen Friche, Bernd Granzen, Barbara Y. Bugg, W. Graydon Harker, Leonard A. Zwelling, Bernard W. Futscher, D. Parker Suttle, and William T. Beck
Cancer Res 1993 53: 1373-1379. [Abstract] [PDF]  

Immunology:

T-Cells Infiltrating Renal Cell Carcinoma Display a Poor Proliferative Response Even Though They Can Produce Interleukin 2 and Express Interleukin 2 Receptors

Jeannine P. Alexander, Seiji Kudoh, Kathryn A. Melsop, Thomas A. Hamilton, Mark G. Edinger, Raymond R. Tubbs, Dante Sica, Laurie Tuason, Eric Klein, Ronald M. Bukowski, and James H. Finke
Cancer Res 1993 53: 1380-1387. [Abstract] [PDF]  

Characterization of Polyclonal and Monoclonal Anti-Taxol Antibodies and Measurement of Taxol in Serum

Jyh-Gang Leu, Bi-Xing Chen, Peter B. Schiff, and Bernard F. Erlanger
Cancer Res 1993 53: 1388-1391. [Abstract] [PDF]  

Disseminated Growth of a Human Multiple Myeloma Cell Line in Mice with Severe Combined Immunodeficiency Disease

Yi-Wu Huang, James A. Richardson, Alex W. Tong, Bing-Qing Zhang, Marvin J. Stone, and Ellen S. Vitetta
Cancer Res 1993 53: 1392-1396. [Abstract] [PDF]  

Tissue Inhibitor of Metalloproteinase 1 Is a Negative Regulator of the Metastatic Ability of a Human Gastric Cancer Cell Line, KKLS, in the Chick Embryo

Yuri Tsuchiya, Hiroshi Sato, Yoshio Endo, Yasunori Okada, Masayosi Mai, Takuma Sasaki, and Motoharu Seiki
Cancer Res 1993 53: 1397-1402. [Abstract] [PDF]  

High-Level Expression of the Ribosomal Protein L19 in Human Breast Tumors That Overexpress erbB-2

John L. Henry, David L. Coggin, and C. Richter King
Cancer Res 1993 53: 1403-1408. [Abstract] [PDF]  

Tumor Biology:

Identification and Characterization of a Novel Matrix-degrading Protease from Hormone-dependent Human Breast Cancer Cells

Yuenian E. Shi, Jeff Torri, Lynn Yieh, Anton Wellstein, Marc E. Lippman, and Robert B. Dickson
Cancer Res 1993 53: 1409-1415. [Abstract] [PDF]  

Chemotaxis and Chemokinesis of Human Prostate Tumor Cell Lines in Response to Human Prostate Stromal Cell Secretory Proteins Containing a Nerve Growth Factor-like Protein

Daniel Djakiew, Beth R. Pflug, Robert Delsite, Makoto Onoda, John H. Lynch, Gloria Arand, and Erik W. Thompson
Cancer Res 1993 53: 1416-1420. [Abstract] [PDF]  

Expression of Thrombospondin (TSP1) and Its Receptors (CD36 and CD51) in Normal, Hyperplastic, and Neoplastic Human Breast

Philippe Clezardin, Lucien Frappart, Magali Clerget, Christine Pechoux, and Pierre D. Delmas
Cancer Res 1993 53: 1421-1430. [Abstract] [PDF]  

Radiation Damage Repair Capacity of Primary Clonogenic Blasts in Acute Lymphoblastic Leukemia

Fatih M. Uckun, Mridula Chandan-Langlie, Waclaw Jaszcz, Vedat Obuz, Kevin Waddick, and Chang W. Song
Cancer Res 1993 53: 1431-1436. [Abstract] [PDF]  

Mucin Synthesis and Secretion in Various Human Epithelial Cancer Cell Lines That Express the MUC-1 Mucin Gene

Rajvir Dahiya, Kyu-Shik Kwak, James C. Byrd, Samuel Ho, Wan-Hee Yoon, and Young S. Kim
Cancer Res 1993 53: 1437-1443. [Abstract] [PDF]  

ß-Fibroblast Growth Factor Expression in Human and Murine Squamous Cell Carcinomas and Its Relationship to Regional Endothelial Cell Proliferation

S. Schultz-Hector and S. Haghayegh
Cancer Res 1993 53: 1444-1449. [Abstract] [PDF]  

Biochemical and Functional Characterization of Aminopeptidase N Expressed by Human Melanoma Cells

Andreas Menrad, David Speicher, Jutta Wacker, and Meenhard Herlyn
Cancer Res 1993 53: 1450-1455. [Abstract] [PDF]  

Expression of BCL-2 Protein Enhances the Survival of Mouse Fibrosarcoid Cells in Tumor Necrosis Factor-mediated Cytotoxicity

Thierry Hennet, Giuseppe Bertoni, Christoph Richter, and Ernst Peterhans
Cancer Res 1993 53: 1456-1460. [Abstract] [PDF]  

Human Cytotoxic T-Cell Lines with Restricted Specificity for Squamous Cell Carcinoma of the Head and Neck

Satoshi Yasumura, Hideki Hirabayashi, Donald R. Schwartz, John F. Toso, Jonas T. Johnson, Ronald B. Herberman, and Theresa L. Whiteside
Cancer Res 1993 53: 1461-1468. [Abstract] [PDF]  

Letter to the Editor:

Correspondence re: S. E. Benner et al., Chemoprevention Strategies for Lung and Upper Aerodigestive Tract Cancer. Cancer Res., 52 (Suppl.): 2758s–2763s, 1992.

Harinder Garewal
Cancer Res 1993 53: 1469 [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 1470-1471. [PDF]  

Announcements:

Recent Death

Cancer Res 1993 53: 1471 [PDF]  

Calendar of Events

Cancer Res 1993 53: 1472 [PDF]  

Erratum:

Effects of Cancer Immunotherapy with Indomethacin and Interleukin-2 on Murine Hemopoietic Stem Cells

Cancer Res 1993 53: 1472 [PDF]  

Evidence fort he Involvement of a Potential Second Tumor Suppressor Gene on Chromosome 17 Distinct from p53 in Malignant Astrocytomas

Cancer Res 1993 53: 1472 [PDF]  

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