Advances in Brief:

Transgenic Mouse Model for Synergistic Effects of Nuclear Oncogenes and Growth Factors in Tumorigenesis: Interaction of c-myc and Transforming Growth Factor in Hepatic Oncogenesis

Hiroko Murakami, Nancy D. Sanderson, Peter Nagy, Pamela A. Marino, Glenn Merlino, and Snorri S. Thorgeirsson
Cancer Res 1993 53: 1719-1723. [Abstract] [PDF]  

Immunohistochemical Localization of Parathyroid Hormone-related Protein in Human Prostate Cancer

Masatsugu Iwamura, P. Anthony di Sant'Agnese, Guan Wu, Cynthia M. Benning, Abraham T. K. Cockett, Leonard J. Deftos, and Per-Anders Abrahamsson
Cancer Res 1993 53: 1724-1726. [Abstract] [PDF]  

In Vivo Inhibition of Insulin-like Growth Factor I Gene Expression by Tamoxifen

Hung T. Huynh, Evelyn Tetenes, Laurie Wallace, and Michael Pollak
Cancer Res 1993 53: 1727-1730. [Abstract] [PDF]  

Ribozyme-mediated Modulation of Human O⁶-Methylguanine-DNA Methyltransferase Expression

Philip M. Potter, Linda C. Harris, Joanna S. Remack, Carol C. Edwards, and Thomas P. Brent
Cancer Res 1993 53: 1731-1734. [Abstract] [PDF]  

Activation of the Abelson Tyrosine Kinase Activity Is Associated with Suppression of Apoptosis in Hemopoietic Cells

Caroline A. Evans, P. Jane Owen-Lynch, Anthony D. Whetton, and Caroline Dive
Cancer Res 1993 53: 1735-1738. [Abstract] [PDF]  

A Structural Role for Metal Ions in the "Wild-type" Conformation of the Tumor Suppressor Protein p53

Pierre Hainaut and Jo Milner
Cancer Res 1993 53: 1739-1742. [Abstract] [PDF]  

Prevention of Orthotopic Human Lung Cancer Growth by Intratracheal Instillation of a Retroviral Antisense K-ras Construct

Renee N. Georges, Tapas Mukhopadhyay, Yujiao Zhang, Nancy Yen, and Jack A. Roth
Cancer Res 1993 53: 1743-1746. [Abstract] [PDF]  

Analysis of the Expression of MRP, the Gene for a New Putative Transmembrane Drug Transporter, in Human Multidrug Resistant Lung Cancer Cell Lines

Guido J. R. Zaman, Carolina H. M. Versantvoort, Jaap J. M. Smit, Elisabeth W. H. M. Eijdems, Marcel de Haas, Alexander J. Smith, Henricus J. Broxterman, Nanno H. Mulder, Elisabeth G. E. de Vries, Frank Baas, and Piet Borst
Cancer Res 1993 53: 1747-1750. [Abstract] [PDF]  

Biochemistry and Biophysics:

Identification of a Putative Tumor Marker in Breast and Colon Cancer

Bangying Su, Francis Kappler, Benjamin S. Szwergold, and Truman R. Brown
Cancer Res 1993 53: 1751-1754. [Abstract] [PDF]  

Entry of Protein Toxins in Polarized Epithelial Cells

Elisabeth L. Melby, Jorunn Jacobsen, Sjur Olsnes, and Kirsten Sandvig
Cancer Res 1993 53: 1755-1760. [Abstract] [PDF]  

Carcinogenesis:

Chromatophoromas and Chromatophore Hyperplasia in Pacific Rockfish (Sebastes spp.)

Mark S. Okihiro, Jeannette A. Whipple, Joseph M. Groff, and David E. Hinton
Cancer Res 1993 53: 1761-1769. [Abstract] [PDF]  

Loss of Differentiation Control in Transformed 3T3 T Proadipocytes

Rodney L. Sparks, Blake J. Allen, Andrea I. Zygmunt, and Ethan E. Strauss
Cancer Res 1993 53: 1770-1776. [Abstract] [PDF]  

Induction of Neoplastic Progression in Syrian Hamster Embryo Cells Treated with Protein Phosphatase Inhibitors

Cynthia A. Afshari, Seiji Kodama, Holly M. Bivins, T. Brian Willard, Hirota Fujiki, and J. Carl Barrett
Cancer Res 1993 53: 1777-1782. [Abstract] [PDF]  

Accumulation of p53 Protein in Human Esophageal Precancerous Lesions: A Possible Early Biomarker for Carcinogenesis

Li-Dong Wang, Jun-Yan Hong, Song-Liang Qiu, Hongkun Gao, and Chung S. Yang
Cancer Res 1993 53: 1783-1787. [Abstract] [PDF]  

Clinical Investigations:

Clinical Value of Determination of Urokinase-type Plasminogen Activator Antigen in Plasma for Detection of Colorectal Cancer: Comparison with Circulating Tumor-associated Antigens CA 19-9 and Carcinoembryonic Antigen

Kurt Huber, Johannes C. Kirchheimer, Astrid Sedlmayer, Cameron Bell, Dorothea Ermler, and Bernd R. Binder
Cancer Res 1993 53: 1788-1793. [Abstract] [PDF]  

Phase I and Pharmacological Study of the Pulmonary Cytotoxin 4-Ipomeanol on a Single Dose Schedule in Lung Cancer Patients: Hepatotoxicity Is Dose Limiting in Humans

Eric K. Rowinsky, Dennis A. Noe, David S. Ettinger, Michaele C. Christian, Barbara G. Lubejko, Elliot K. Fishman, Susan E. Sartorius, Michael R. Boyd, and Ross C. Donehower
Cancer Res 1993 53: 1794-1801. [Abstract] [PDF]  

Endocrinology:

Characterization of the Aryl Hydrocarbon Receptor and Aryl Hydrocarbon Responsiveness in Human Ovarian Carcinoma Cell Lines

C. Rowlands, V. Krishnan, X. Wang, M. Santostefano, S. Safe, W. R. Miller, and S. Langdon
Cancer Res 1993 53: 1802-1807. [Abstract] [PDF]  

Glucocorticoids Coordinately Disrupt a Transforming Growth Factor Autocrine Loop and Suppress the Growth of 13762NF-derived Con8 Rat Mammary Adenocarcinoma Cells

David B. Alexander, Luis Goya, Melanie K. Webster, Tokuko Haraguchi, and Gary L. Firestone
Cancer Res 1993 53: 1808-1815. [Abstract] [PDF]  

Overexpression of Transforming Growth Factor Overrides the Glucocorticoid-mediated Suppression of Con8 Mammary Tumor Cell Growth in Vitro and in Vivo

Luis Goya, Dave B. Alexander, Melanie K. Webster, Francis G. Kern, Raphael C. Guzman, Satyabrata Nandi, and Gary L. Firestone
Cancer Res 1993 53: 1816-1822. [Abstract] [PDF]  

Ovarian Cancers Express and Process Progastrin

Wouter W. van Solinge, Lars Ødum, and Jens F. Rehfeld
Cancer Res 1993 53: 1823-1828. [Abstract] [PDF]  

Experimental Therapeutics:

Modulation of Both Cisplatin Nephrotoxicity and Drug Resistance in Murine Bladder Tumor by Controlling Metallothionein Synthesis

Masahiko Satoh, Debra M. Kloth, Salam A. Kadhim, Joseph L. Chin, Akira Naganuma, Nobumasa Imura, and M. George Cherian
Cancer Res 1993 53: 1829-1832. [Abstract] [PDF]  

Antiangiogenic Effects of the Quinoline-3-Carboxamide Linomide

Jasminka Vukanovic, Antonino Passaniti, Takahiko Hirata, Richard J. Traystman, Beryl Hartley-Asp, and John T. Isaacs
Cancer Res 1993 53: 1833-1837. [Abstract] [PDF]  

Protection of Bone Marrow Stromal Cells from the Toxic Effects of Cyclophosphamide in Vivo and of ASTA-Z 7557 and Etoposide in Vitro by Ammonium Trichloro(dioxyethylene-O-O')tellurate (AS101)

Yona Kalechman, Iris Sotnik-Barkai, Michael Albeck, and Benjamin Sredni
Cancer Res 1993 53: 1838-1844. [Abstract] [PDF]  

Apoptosis Induced by Anthracycline Antibiotics in P388 Parent and Multidrug-resistant Cells

Yi-He Ling, Waldemar Priebe, and Roman Perez-Soler
Cancer Res 1993 53: 1845-1852. [Abstract] [PDF]  

Constitutive Expression of Human Bcl-2 Modulates Nitrogen Mustard and Camptothecin Induced Apoptosis

M. I. Walton, D. Whysong, P. M. O'Connor, D. Hockenbery, S. J. Korsmeyer, and K. W. Kohn
Cancer Res 1993 53: 1853-1861. [Abstract] [PDF]  

Inhibition of Protein Tyrosine Phosphatase by the Antitumor Agent Gallium Nitrate

Margareta M. Berggren, Leigh Ann Burns, Robert T. Abraham, and Garth Powis
Cancer Res 1993 53: 1862-1866. [Abstract] [PDF]  

Yeast Cells Can Enter a Quiescent State through G₁, S, G₂, or M Phase of the Cell Cycle

Wen Wei, Paul Nurse, and Daniel Broek
Cancer Res 1993 53: 1867-1870. [Abstract] [PDF]  

Immunology:

Human Myelomonocytic Cell Line THP-1 Produces a Novel Growth-promoting Factor with a Wide Target Cell Spectrum

Akihiko Takeuchi, Hidetoshi Hayashi, Yukiko Naito, Tohru Baba, Takuya Tamatani, and Kikuo Onozaki
Cancer Res 1993 53: 1871-1876. [Abstract] [PDF]  

Molecular Biology and Genetics:

An Anticancer Drug-sensitive Murine Erythroleukemia Clone: Implications for the Mechanism of Action of Antineoplastic Drugs

Richard D. Dinnen, Carl F. Robinow, and Kaney Ebisuzaki
Cancer Res 1993 53: 1877-1882. [Abstract] [PDF]  

Alterations of the p53 Tumor Suppressor Gene and Its Association with Activation of the c-K-ras-2 Protooncogene in Premalignant and Malignant Lesions of the Human Uterine Endometrium

Takayuki Enomoto, Masami Fujita, Masaki Inoue, Jerry M. Rice, Ryuichi Nakajima, Osamu Tanizawa, and Taisei Nomura
Cancer Res 1993 53: 1883-1888. [Abstract] [PDF]  

Altered Messenger RNA and Unique Mutational Profiles of p53 and Rb in Human Esophageal Carcinomas

Ying Huang, Stephen J. Meltzer, Jing Yin, Yi Tong, Esther H. Chang, Shiv Srivastava, Tim McDaniel, Robert F. Boynton, and Zhi-Qiang Zou
Cancer Res 1993 53: 1889-1894. [Abstract] [PDF]  

Deletion of 1p36 as a Primary Chromosomal Aberration in Intestinal Tumorigenesis

Georgia Bardi, Nikos Pandis, Claus Fenger, Ole Kronborg, Lilian Bomme, and Sverre Heim
Cancer Res 1993 53: 1895-1898. [Abstract] [PDF]  

Ultrastructural Localization and Fluctuation in the Level of the Proliferating Cell Nuclear Antigen and myc Oncoproteins in Synchronized Neuroblastoma Cells

Yair Gazitt, Gregory W. Erdos, and Robert J. Cohen
Cancer Res 1993 53: 1899-1905. [Abstract] [PDF]  

Mutation of the Ki-ras Protooncogene in Human Endometrial Hyperplasia and Carcinoma

Hiroshi Sasaki, Hiroshi Nishii, Hiroyuki Takahashi, Akio Tada, Masakuni Furusato, Yoshiteru Terashima, Gene P. Siegal, Sheryl L. Parker, Matthew F. Kohler, Andrew Berchuck, and Jeff Boyd
Cancer Res 1993 53: 1906-1910. [Abstract] [PDF]  

Tumor Biology:

Receptor for Urokinase Is Present in Tumor-associated Macrophages in Ductal Breast Carcinoma

C. Pyke, N. Græm, E. Ralfkiær, E. Rønne, G. Høyer-Hansen, N. Brünner, and K. Danø
Cancer Res 1993 53: 1911-1915. [Abstract] [PDF]  

Ubiquitin-Ribosomal Protein S27a Gene Overexpressed in Human Colorectal Carcinoma Is an Early Growth Response Gene

Jau Min Wong, Ken-ichi Mafune, Hsiukang Yow, Elissa N. Rivers, T. S. Ravikumar, Glenn D. Steele, Jr., and Lan Bo Chen
Cancer Res 1993 53: 1916-1920. [Abstract] [PDF]  

Enhanced Immunosuppressive Activity Associated with Metastatic Lymphoma Cells

Weimin Hao, Thomas L. McDonald, Kenneth W. Brunson, and Shantaram S. Joshi
Cancer Res 1993 53: 1921-1928. [Abstract] [PDF]  

Wild-type Adenovirus Type 5 Transforming Genes Function as Transdominant Suppressors of Oncogenesis in Mutant Adenovirus Type 5 Transformed Rat Embryo Fibroblast Cells

Zao-Zhong Su, Jorge A. Leon, Hongping Jiang, Vincent N. Austin, Stephen G. Zimmer, and Paul B. Fisher
Cancer Res 1993 53: 1929-1938. [Abstract] [PDF]  

Tumor Necrosis Factor as an Autocrine and Paracrine Growth Factor for Ovarian Cancer: Monokine Induction of Tumor Cell Proliferation and Tumor Necrosis Factor Expression

S. Wu, C. M. Boyer, R. S. Whitaker, A. Berchuck, J. R. Wiener, J. B. Weinberg, and R. C. Bast, Jr.
Cancer Res 1993 53: 1939-1944. [Abstract] [PDF]  

Detection of DNA Strand Breaks in Individual Apoptotic Cells by the in Situ Terminal Deoxynucleotidyl Transferase and Nick Translation Assays

Wojciech Gorczyca, Jianping Gong, and Zbigniew Darzynkiewicz
Cancer Res 1993 53: 1945-1951. [Abstract] [PDF]  

Radiation-enhanced Expression of Major Histocompatibility Complex Class I Antigen H-2D^b in B16 Melanoma Cells

Stephen H. Hauser, Lido Calorini, David E. Wazer, and Sebastiano Gattoni-Celli
Cancer Res 1993 53: 1952-1955. [Abstract] [PDF]  

Amplification of c-myc but not of c-erbB-2 Is Associated with High Proliferative Capacity in Breast Cancer

H. Kreipe, H. Feist, L. Fischer, J. Felgner, K. Heidorn, L. Mettler, and R. Parwaresch
Cancer Res 1993 53: 1956-1961. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 1962-1963. [PDF]  

Recent Deaths

Cancer Res 1993 53: 1963 [PDF]  

Calendar of Events

Cancer Res 1993 53: 1964 [PDF]  

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