Advances in Brief:

The Androgen Receptor Status of Neuroendocrine Cells in Human Benign and Malignant Prostatic Tissue

Stephen Y. Nakada, P. A. di Sant'Agnese, Robin A. Moynes, Richard A. Hiipakka, Shutsung Liao, Abraham T. K. Cockett, and Per-Anders Abrahamsson
Cancer Res 1993 53: 1967-1970. [Abstract] [PDF]  

Inhibition of Cell Motility after nm23 Transfection of Human and Murine Tumor Cells

Jason D. Kantor, Beth McCormick, Patricia S. Steeg, and Bruce R. Zetter
Cancer Res 1993 53: 1971-1973. [Abstract] [PDF]  

BIBW 22, a Dipyridamole Analogue, Acts as a Bifunctional Modulator on Tumor Cells by Influencing Both P-Glycoprotein and Nucleoside Transport

Hong-xing Chen, Uwe Bamberger, Armin Heckel, Xin Guo, and Yung-chi Cheng
Cancer Res 1993 53: 1974-1977. [Abstract] [PDF]  

Footprinting of Individual Tumors and Their Variants by Constitutive Cytokine Expression Patterns

Lisa A. Pekarek, Ralph R. Weichselbaum, Michael A. Beckett, James Nachman, and Hans Schreiber
Cancer Res 1993 53: 1978-1981. [Abstract] [PDF]  

Tumor Necrosis Factor Acts as a Tumor Promoter in BALB/3T3 Cell Transformation

Atsumasa Komori, Jun Yatsunami, Masami Suganuma, Sachiko Okabe, Saori Abe, Ayako Sakai, Kiyoshi Sasaki, and Hirota Fujiki
Cancer Res 1993 53: 1982-1985. [Abstract] [PDF]  

Amplification of Cyclin Genes in Colorectal Carcinomas

Fredrick S. Leach, Stephen J. Elledge, Charles J. Sherr, James K. V. Willson, Sanford Markowitz, Kenneth W. Kinzler, and Bert Vogelstein
Cancer Res 1993 53: 1986-1989. [Abstract] [PDF]  

Two Distinct Regions Involved in 1p Deletion in Human Primary Breast Cancer

Ivan Bièche, Marie-Hélène Champème, Florence Matifas, Craig S. Cropp, Robert Callahan, and Rosette Lidereau
Cancer Res 1993 53: 1990-1994. [Abstract] [PDF]  

Association of Glyceraldehyde-3-phosphate Dehydrogenase Expression with Cell Motility and Metastatic Potential of Rat Prostatic Adenocarcinoma

Daniel E. Epner, Alan W. Partin, Jack A. Schalken, John T. Isaacs, and Donald S. Coffey
Cancer Res 1993 53: 1995-1997. [Abstract] [PDF]  

Biochemistry and Biophysics:

Modulation of Murine B16F10 Melanoma Plasminogen Activator Production by a Synthetic Peptide Derived from the Laminin A Chain

M. Sharon Stack, Robert D. Gray, and Salvatore V. Pizzo
Cancer Res 1993 53: 1998-2004. [Abstract] [PDF]  

Coordinate Oncodevelopmental Modulation of Alternative Splicing of Fibronectin Pre-Messenger RNA at ED-A, ED-B, and CS1 Regions in Human Liver Tumors

Fumitaka Oyama, Setsuo Hirohashi, Michiie Sakamoto, Koiti Titani, and Kiyotoshi Sekiguchi
Cancer Res 1993 53: 2005-2011. [Abstract] [PDF]  

Hypersensitivity of Cockayne's Syndrome Cells to Camptothecin Is Associated with the Generation of Abnormally High Levels of Double Strand Breaks in Nascent DNA

Shoshana Squires, Anderson J. Ryan, Helen L. Strutt, and Robert T. Johnson
Cancer Res 1993 53: 2012-2019. [Abstract] [PDF]  

Carcinogenesis:

Coordinate Expression of N-myc 2 and Insulin-like Growth Factor II in Precancerous Altered Hepatic Foci in Woodchuck Hepatitis Virus Carriers

D. Yang, E. Alt, and C. E. Rogler
Cancer Res 1993 53: 2020-2027. [Abstract] [PDF]  

Roles of Human Hepatic and Pulmonary Cytochrome P450 Enzymes in the Metabolism of the Environmental Carcinogen 6-Nitrochrysene

Young-Heum Chae, Chul-Ho Yun, F. Peter Guengerich, Fred F. Kadlubar, and Karam El-Bayoumy
Cancer Res 1993 53: 2028-2034. [Abstract] [PDF]  

Biological Consequences of Overexpression of a Transfected c-erbB-2 Gene in Immortalized Human Bronchial Epithelial Cells

Masayuki Noguchi, Masakazu Murakami, William Bennett, Ruth Lupu, Ferdinand Hui, Jr., Curtis C. Harris, and Brenda I. Gerwin
Cancer Res 1993 53: 2035-2043. [Abstract] [PDF]  

Clinical Investigations:

Coexpression of Messenger RNA for TRK Protooncogene and Low Affinity Nerve Growth Factor Receptor in Neuroblastoma with Favorable Prognosis

Per Kogner, Gisela Barbany, Carlo Dominici, Manuel A. Castello, Giuseppe Raschellá, and Håkan Persson
Cancer Res 1993 53: 2044-2050. [Abstract] [PDF]  

Experimental Therapeutics:

A Newly Synthesized Bifunctional Inhibitor, W-77, Enhances Adriamycin Activity against Human Ovarian Carcinoma Cells

Osamu Maeda, Motomu Terasawa, Tomohiko Ishikawa, Hidenori Oguchi, Kimio Mizuno, Michiyasu Kawai, Fumitaka Kikkawa, Yutaka Tomoda, and Hiroyoshi Hidaka
Cancer Res 1993 53: 2051-2056. [Abstract] [PDF]  

Inhibition of Doxorubicin-induced Apoptosis in Vivo by 2-Deoxy-D-glucose

N. S. Thakkar and C. S. Potten
Cancer Res 1993 53: 2057-2060. [Abstract] [PDF]  

Plasma Pharmacokinetics of Vinblastine and the Investigational Vinca Alkaloid N-(Deacetyl-O-4-vinblastoyl-23)-L-ethyl Isoleucinate in Mice as Determined by High-Performance Liquid Chromatography

Olaf van Tellingen, Jos H. Beijnen, Willem J. Nooijen, and Auke Bult
Cancer Res 1993 53: 2061-2065. [Abstract] [PDF]  

Glutathione Depletion by L-Buthionine Sulfoximine Antagonizes Taxol Cytotoxicity

James E. Liebmann, Stephen M. Hahn, John A. Cook, Claudia Lipschultz, James B. Mitchell, and Dwight C. Kaufman
Cancer Res 1993 53: 2066-2070. [Abstract] [PDF]  

Growth Inhibition of Hormone-responsive and -resistant Human Breast Cancer Cells in Culture by N¹, N¹²-Bis(ethyl)spermine

Nancy E. Davidson, Amy R. Mank, Laura J. Prestigiacomo, Raymond J. Bergeron, and Robert A. Casero, Jr.
Cancer Res 1993 53: 2071-2075. [Abstract] [PDF]  

Influence of Vascular Thermotolerance on the Heat-induced Changes in Blood Flow, pO₂, and Cell Survival in Tumors

Jyh-Cherng Lin and Chang W. Song
Cancer Res 1993 53: 2076-2080. [Abstract] [PDF]  

Cell Cycle Arrest and Growth Inhibition by the Protein Kinase Antagonist UCN-01 in Human Breast Carcinoma Cells

Caroline M. Seynaeve, Maryalice Stetler-Stevenson, Sandra Sebers, Gurmeet Kaur, Edward A. Sausville, and Peter J. Worland
Cancer Res 1993 53: 2081-2086. [Abstract] [PDF]  

A Synthetic Matrix Metalloproteinase Inhibitor Decreases Tumor Burden and Prolongs Survival of Mice Bearing Human Ovarian Carcinoma Xenografts

Bernard Davies, Peter D. Brown, Nick East, Michael J. Crimmin, and Frances R. Balkwill
Cancer Res 1993 53: 2087-2091. [Abstract] [PDF]  

The Spatial Distribution of Immunotoxins in Solid Tumors: Assessment by Quantitative Autoradiography

Cynthia Sung, Robert L. Dedrick, Walter A. Hall, Patricia A. Johnson, and Richard J. Youle
Cancer Res 1993 53: 2092-2099. [Abstract] [PDF]  

Induction of Differentiation in Myeloid Leukemia Cell Lines and Acute Promyelocytic Leukemia Cells by Liposomal All-trans-Retinoic Acid

Johannes Drach, Gabriel Lopez-Berestein, Teresa McQueen, Michael Andreeff, and Kapil Mehta
Cancer Res 1993 53: 2100-2104. [Abstract] [PDF]  

DNA Repair and Cell Cycle Interactions in Radiation Sensitization by the Topoisomerase II Poison Etoposide

Nicole Giocanti, Christophe Hennequin, Jacques Balosso, Marie Mahler, and Vincent Favaudon
Cancer Res 1993 53: 2105-2111. [Abstract] [PDF]  

Immunology:

Interleukin 3 Enhances Development of Tumor-reactive Cytotoxic Cells by a CD4-dependent Mechanism

Beth A. Pulaski, Alexander J. McAdam, Elizabeth K. Hutter, Stephen Biggar, Edith M. Lord, and John G. Frelinger
Cancer Res 1993 53: 2112-2117. [Abstract] [PDF]  

Serum Interleukin 6 Levels Are Elevated in Lymphoma Patients and Correlate with Survival in Advanced Hodgkin's Disease and with B Symptoms

Razelle Kurzrock, John Redman, Fernando Cabanillas, Donnah Jones, Jeanne Rothberg, and Moshe Talpaz
Cancer Res 1993 53: 2118-2122. [Abstract] [PDF]  

Molecular Biology and Genetics:

Genetic Construction, Expression, and Characterization of a Single Chain Anti-Carcinoma Antibody Fused to ß-Lactamase

Stephen C. Goshorn, Håkan P. Svensson, David E. Kerr, John E. Somerville, Peter D. Senter, and H. Perry Fell
Cancer Res 1993 53: 2123-2127. [Abstract] [PDF]  

p53 Mutation Is a Common Genetic Event in Ovarian Carcinoma

Ben J. Milner, Lindsey A. Allan, Diana M. Eccles, Henry C. Kitchener, Robert C. F. Leonard, Kevin F. Kelly, David E. Parkin, and Neva E. Haites
Cancer Res 1993 53: 2128-2132. [Abstract] [PDF]  

Tumor Biology:

Effects of Cisplatin on the Induction of Apoptosis in Proliferating Hepatoma Cells and Nonproliferating Immature Thymocytes

Dyfed L. Evans and Caroline Dive
Cancer Res 1993 53: 2133-2139. [Abstract] [PDF]  

Chromosome Abnormalities in Eighty-three Head and Neck Squamous Cell Carcinomas: Influence of Culture Conditions on Karyotypic Pattern

Yuesheng Jin, Fredrik Mertens, Nils Mandahl, Sverre Heim, Cecilia Olegård, Johan Wennerberg, Anders Biörklund, and Felix Mitelman
Cancer Res 1993 53: 2140-2146. [Abstract] [PDF]  

Analysis of Ly-1⁺ B-Cell Populations and IgH Rearrangements in "Normal" Spleens and in Lymphomas of AKR/J and AKR Fv-1^b Mice

A. Rosner, A. Peled, N. Haran-Ghera, and E. Canaani
Cancer Res 1993 53: 2147-2153. [Abstract] [PDF]  

Baculovirus Recombinants Expressing the Human Carcinoembryonic Antigen Gene

Michael L. Salgaller, Roberto Bei, Jeffrey Schlom, Diane J. Poole, and Paul F. Robbins
Cancer Res 1993 53: 2154-2161. [Abstract] [PDF]  

Transforming Growth Factor- Expression Produces Only Morphological Transformants of Diploid Human Fibroblasts

William H. Brondyk, Gregory C. Kujoth, and William E. Fahl
Cancer Res 1993 53: 2162-2167. [Abstract] [PDF]  

Fibroblast Growth Factor 4 Transfection of MCF-7 Cells Produces Cell Lines That Are Tumorigenic and Metastatic in Ovariectomized or Tamoxifen-treated Athymic Nude Mice

Sandra W. McLeskey, Junichi Kurebayashi, Susan F. Honig, James Zwiebel, Marc E. Lippman, Robert B. Dickson, and Francis G. Kern
Cancer Res 1993 53: 2168-2177. [Abstract] [PDF]  

Quantitative Demonstration of Spontaneous Metastasis by MCF-7 Human Breast Cancer Cells Cotransfected with Fibroblast Growth Factor 4 and LacZ

Junichi Kurebayashi, Sandra W. McLeskey, Michael D. Johnson, Marc E. Lippman, Robert B. Dickson, and Francis G. Kern
Cancer Res 1993 53: 2178-2187. [Abstract] [PDF]  

Letters to the Editor:

Correspondence re: H. Nagasawa and J. B. Little, Induction of Sister Chromatid Exchanges by Extremely Low Doses of -Particles. Cancer Res., 52: 6394–6396, 1992

John T. Leith
Cancer Res 1993 53: 2188 [PDF]  

Correspondence re: H. Nagasawa and J. B. Little, Induction of Sister Chromatid Exchanges by Extremely Low Doses of -Particles. Cancer Res., 52: 6394–6396, 1992—Reply

Hatsumi Nagasawa and John B. Little
Cancer Res 1993 53: 2188 [PDF]  

Meeting Report:

Environmental Carcinogenesis and Its Prevention: The Head and Neck Cancer Model

Cancer Res 1993 53: 2189-2191. [PDF]  

Fourth Annual Pezcoller Symposium—Adhesion Molecules: Cellular Recognition Mechanisms

M. Hemler and E. Mihich
Cancer Res 1993 53: 2192-2194. [PDF]  

Articles:

Announcements

Cancer Res 1993 53: 2195-2196. [PDF]  

Announcements:

Recent Deaths

Cancer Res 1993 53: 2196 [PDF]  

Calendar of Events

Cancer Res 1993 53: 2196-2197. [PDF]  

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