Advances in Brief:

Suppression of Tumorigenicity of Human Prostate Cancer Cells by Introduction of Human Chromosome del(12)(q13)

Nathalie G. Bérubé, Marsha D. Speevak, and Mario Chevrette
Cancer Res 1994 54: 3077-3081. [Abstract] [PDF]  

Effects of Hypoxia on Detoxicating Enzyme Activity and Expression in HT29 Colon Adenocarcinoma Cells

P. J. O'Dwyer, K-S. Yao, P. Ford, A. K. Godwin, and M. Clayton
Cancer Res 1994 54: 3082-3087. [Abstract] [PDF]  

Reversal of Multidrug Resistance by RU 486

Donald J. Gruol, Michele C. Zee, Joseph Trotter, and Suzanne Bourgeois
Cancer Res 1994 54: 3088-3091. [Abstract] [PDF]  

A Negative Regulatory Factor Is Missing in a Human Metastatic Breast Cancer Cell Line

Denise M. Stover, Indira Carey, Richard J. Garzon, and Zendra E. Zehner
Cancer Res 1994 54: 3092-3095. [Abstract] [PDF]  

Pharmacokinetics of the in Vivo and in Vitro Conversion of 9-Nitro-20(S)-camptothecin to 9-Amino-20(S)-camptothecin in Humans, Dogs, and Mice

Hellmuth R. Hinz, Nicholas J. Harris, Ethan A. Natelson, and Beppino C. Giovanella
Cancer Res 1994 54: 3096-3100. [Abstract] [PDF]  

Wilms' Tumor Suppressor Gene Expression in Rat and Human Mesothelioma

Cheryl Walker, Fons Rutten, Xiaoquin Yuan, Harvey Pass, Daphne M. Mew, and Jeff Everitt
Cancer Res 1994 54: 3101-3106. [Abstract] [PDF]  

Amplification and Overexpression of the Cyclin D1 Gene in Aggressive Human Hepatocellular Carcinoma

Naoshi Nishida, Yoshihiro Fukuda, Toshiki Komeda, Ryuichi Kita, Takehiro Sando, Motonobu Furukawa, Masahiro Amenomori, Icho Shibagaki, Kazuwa Nakao, Mituo Ikenaga, and Kanji Ishizaki
Cancer Res 1994 54: 3107-3110. [Abstract] [PDF]  

Loss of Heterozygosity for 10q22-10qter in Malignant Melanoma Progression

Rudolf A. Herbst, Jürgen Weiss, Alexander Ehnis, Webster K. Cavenee, and Karen C. Arden
Cancer Res 1994 54: 3111-3114. [Abstract] [PDF]  

Uterotrophic Actions of Estradiol and Tamoxifen Are Associated with Inhibition of Uterine Insulin-like Growth Factor Binding Protein 3 Gene Expression

Hung Huynh and Michael Pollak
Cancer Res 1994 54: 3115-3119. [Abstract] [PDF]  

Inverse Relation of E-Cadherin and Autocrine Motility Factor Receptor Expression as a Prognostic Factor in Patients with Bladder Carcinomas

Thomas Otto, Walter Birchmeier, Ulrich Schmidt, Axel Hinke, Jörg Schipper, Herbert Rübben, and Avraham Raz
Cancer Res 1994 54: 3120-3123. [Abstract] [PDF]  

Recognition of Tyrosinase by Tumor-infiltrating Lymphocytes from a Patient Responding to Immunotherapy

Paul F. Robbins, Mona El-Gamil, Yutaka Kawakami, and Steven A. Rosenberg
Cancer Res 1994 54: 3124-3126. [Abstract] [PDF]  

A Common Region of Homozygous Deletion in Malignant Human Gliomas Lies between the IFN/ Gene Cluster and the D9S171 Locus

Koichi Ichimura, Esther E. Schmidt, Narihito Yamaguchi, C. David James, and V. Peter Collins
Cancer Res 1994 54: 3127-3130. [Abstract] [PDF]  

Identification of a p53-dependent Negative Response Element in the bcl-2 Gene

Toshiyuki Miyashita, Masayoshi Harigai, Motoi Hanada, and John C. Reed
Cancer Res 1994 54: 3131-3135. [Abstract] [PDF]  

Staurosporine Blocks Cell Progression through G₁ between the Cyclin D and Cyclin E Restriction Points

Jianping Gong, Frank Traganos, and Zbigniew Darzynkiewicz
Cancer Res 1994 54: 3136-3139. [Abstract] [PDF]  

Biochemistry and Biophysics:

Induction of Tamoxifen-4-hydroxylation by 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), ß-Naphthoflavone (ßNF), and Phenobarbital (PB) in Avian Liver: Identification of P450 TCDD_AA as Catalyst of 4-Hydroxylation Induced by TCDD and ßNF

David Kupfer, Chitra Mani, Charis A. Lee, and Arleen B. Rifkind
Cancer Res 1994 54: 3140-3144. [Abstract] [PDF]  

Carcinogenesis:

Colocalized Alterations in Connexin32 and Cytochrome P450IIB1/2 by Phenobarbital and Related Liver Tumor Promoters

Mark J. Neveu, Karlee L. Babcock, Elliot L. Hertzberg, David L. Paul, Bruce J. Nicholson, and Henry C. Pitot
Cancer Res 1994 54: 3145-3152. [Abstract] [PDF]  

Dysregulation of Epidermal Growth Factor Receptor Expression in Premalignant Lesions during Head and Neck Tumorigenesis

Dong M. Shin, Jae Y. Ro, Waun Ki Hong, and Walter N. Hittelman
Cancer Res 1994 54: 3153-3159. [Abstract] [PDF]  

Epidermal Growth Factor Suppresses Insulin-like Growth Factor Binding Protein 3 Levels in Human Papillomavirus Type 16-immortalized Cervical Epithelial Cells and Thereby Potentiates the Effects of Insulin-like Growth Factor 1

Joan R. Hembree, Chapla Agarwal, and Richard L. Eckert
Cancer Res 1994 54: 3160-3166. [Abstract] [PDF]  

Protection by Galanin against Gastric Carcinogenesis Induced by N-Methyl-N'-nitro-N-nitrosoguanidine in Wistar Rats

Hiroyasu Iishi, Masaharu Tatsuta, Miyako Baba, Hiroyuki Uehara, and Akihiko Nakaizumi
Cancer Res 1994 54: 3167-3170. [Abstract] [PDF]  

Increased Formation of Oxidative DNA Damage, 8-Hydroxydeoxyguanosine, in Human Livers with Chronic Hepatitis

Ryuya Shimoda, Makoto Nagashima, Michiie Sakamoto, Naohito Yamaguchi, Setsuo Hirohashi, Jun Yokota, and Hiroshi Kasai
Cancer Res 1994 54: 3171-3172. [Abstract] [PDF]  

In Vivo Enhancement of Genomic Instability in Minisatellite Sequences of Mouse C3H/10T Cells Transformed in Vitro by X-Rays

Benoit Paquette and John B. Little
Cancer Res 1994 54: 3173-3178. [Abstract] [PDF]  

Endocrinology:

Functional Insulin and Insulin-like Growth Factor-1 Receptors Are Preferentially Expressed in Multiple Myeloma Cell Lines as Compared to B-Lymphoblastoid Cell Lines

Gregory G. Freund, Donald T. Kulas, Barbara A. Way, and Robert A. Mooney
Cancer Res 1994 54: 3179-3185. [Abstract] [PDF]  

Epidemiology:

Fermented Dairy Products, Calcium, and Colorectal Cancer in the Netherlands Cohort Study

Ellen Kampman, R. Alexandra Goldbohm, Piet A. van den Brandt, and Pieter van 't Veer
Cancer Res 1994 54: 3186-3190. [Abstract] [PDF]  

Experimental Therapeutics:

Mechanism of Action of the Antileukemic Xanthone Psorospermin: DNA Strand Breaks, Abasic Sites, and Protein-DNA Cross-Links

Paskasari A. Permana, David K. Ho, John M. Cassady, and Robert M. Snapka
Cancer Res 1994 54: 3191-3195. [Abstract] [PDF]  

Metabolism of Bioreductive Antitumor Compounds by Purified Rat and Human DT-Diaphorases

Howard D. Beall, R. Timothy Mulcahy, David Siegel, Robert D. Traver, Neil W. Gibson, and David Ross
Cancer Res 1994 54: 3196-3201. [Abstract] [PDF]  

Transmembrane Orientation and Topogenesis of the Third and Fourth Membrane-spanning Regions of Human P-Glycoprotein (MDR1)

William R. Skach and Vishwanath R. Lingappa
Cancer Res 1994 54: 3202-3209. [Abstract] [PDF]  

CGP 48664, a New S-Adenosylmethionine Decarboxylase Inhibitor with Broad Spectrum Antiproliferative and Antitumor Activity

Urs Regenass, Helmut Mett, Jaroslav Stanek, Marcel Mueller, Debora Kramer, and Carl W. Porter
Cancer Res 1994 54: 3210-3217. [Abstract] [PDF]  

Metabolism of 2',2'-Difluoro-2'-Deoxycytidine and Radiation Sensitization of Human Colon Carcinoma Cells

Donna S. Shewach, Tina M. Hahn, Emily Chang, Larry W. Hertel, and Theodore S. Lawrence
Cancer Res 1994 54: 3218-3223. [Abstract] [PDF]  

Synergistic Inhibition of T-Lymphoblastic Leukemic CCRF-CEM Cell Growth by Gallium and Recombinant Human -Interferon through Action on Cellular Iron Uptake

Christopher R. Chitambar, Janine P. Wereley, and Riaz-Ul-Haq
Cancer Res 1994 54: 3224-3228. [Abstract] [PDF]  

An Antibody Which Specifically Recognizes Prelamin A but not Mature Lamin A: Application to Detection of Blocks in Farnesylation-dependent Protein Processing

Michael Sinensky, Kelley Fantle, and Marguerite Dalton
Cancer Res 1994 54: 3229-3232. [Abstract] [PDF]  

Immunology:

Involvement of Very Late Activation Antigen 4 (VLA-4) and Vascular Cell Adhesion Molecule 1 (VCAM-1) in Tumor Necrosis Factor Enhancement of Experimental Metastasis

Hitoshi Okahara, Hideo Yagita, Kensuke Miyake, and Ko Okumura
Cancer Res 1994 54: 3233-3236. [Abstract] [PDF]  

Molecular Biology and Genetics:

Preferential Alternative Splicing in Cancer Generates a K-sam Messenger RNA with Higher Transforming Activity

Hiroshi Itoh, Yutaka Hattori, Hiromi Sakamoto, Hideshi Ishii, Tatsuya Kishi, Hiroki Sasaki, Teruhiko Yoshida, Masashi Koono, Takashi Sugimura, and Masaaki Terada
Cancer Res 1994 54: 3237-3241. [Abstract] [PDF]  

Tumor Biology:

Expression of Interleukin 8 Correlates with the Metastatic Potential of Human Melanoma Cells in Nude Mice

Rakesh K. Singh, Mordechai Gutman, Robert Radinsky, Corazon D. Bucana, and Isaiah J. Fidler
Cancer Res 1994 54: 3242-3247. [Abstract] [PDF]  

Increased Expression of DNA Topoisomerase I Gene and Collateral Sensitivity to Camptothecin in Human Cisplatin-resistant Bladder Cancer Cells

Shuji Kotoh, Seiji Naito, Akira Yokomizo, Joichi Kumazawa, Keizo Asakuno, Kimitoshi Kohno, and Michihiko Kuwano
Cancer Res 1994 54: 3248-3252. [Abstract] [PDF]  

Bcl-2 Inhibits Chemotherapy-induced Apoptosis in Neuroblastoma

Mukund Dole, Gabriel Nuñez, Audrea K. Merchant, Jonathan Maybaum, Christopher K. Rode, Craig A. Bloch, and Valerie P. Castle
Cancer Res 1994 54: 3253-3259. [Abstract] [PDF]  

c-erbB-2/neu Overexpression Enhances Metastatic Potential of Human Lung Cancer Cells by Induction of Metastasis-associated Properties

Dihua Yu, Shan-Shue Wang, Kim M. Dulski, Chun-Ming Tsai, Garth L. Nicolson, and Mien-Chie Hung
Cancer Res 1994 54: 3260-3266. [Abstract] [PDF]  

Effects of Antisense Glial Fibrillary Acidic Protein Complementary DNA on the Growth, Invasion, and Adhesion of Human Astrocytoma Cells

James T. Rutka, Sherri Lynn Hubbard, Kouzou Fukuyama, Kazuhito Matsuzawa, Peter B. Dirks, and Laurence E. Becker
Cancer Res 1994 54: 3267-3272. [Abstract] [PDF]  

Allelic Loss in Locally Metastatic, Multisampled Prostate Cancer

Wael A. Sakr, Jill A. Macoska, Philip Benson, David J. Grignon, Sandra R. Wolman, J. Edson Pontes, and John D. Crissman
Cancer Res 1994 54: 3273-3277. [Abstract] [PDF]  

Characterization of Five New Cell Lines Derived from Human Primitive Neuroectodermal Tumors of the Central Nervous System

Torsten Pietsch, Thorsten Scharmann, Christa Fonatsch, Dietmar Schmidt, Reinhard Öckler, Dorothee Freihoff, Steffen Albrecht, Otmar D. Wiestler, Paul Zeltzer, and Hansjörg Riehm
Cancer Res 1994 54: 3278-3287. [Abstract] [PDF]  

Potentiation by Specific Short-Chain Fatty Acids of Differentiation and Apoptosis in Human Colonic Carcinoma Cell Lines

Barbara G. Heerdt, Michele A. Houston, and Leonard H. Augenlicht
Cancer Res 1994 54: 3288-3294. [Abstract] [PDF]  

A Dominated and Resistant Subpopulation Causes Regrowth after Response to 1,3-Bis(2-chloroethyl)-1-nitrosourea Treatment of a Heterogeneous Small Cell Lung Cancer Xenograft in Nude Mice

Kristian Aabo, Henrik Roed, Lars L. Vindeløv, and Mogens Spang-Thomsen
Cancer Res 1994 54: 3295-3299. [Abstract] [PDF]  

Enhancement of the Expression of Urokinase-Type Plasminogen Activator from PC-3 Human Prostate Cancer Cells by Thrombin

Etsuo Yoshida, Elaine N. Verrusio, Hisashi Mihara, Doyeun Oh, and Hau C. Kwaan
Cancer Res 1994 54: 3300-3304. [Abstract] [PDF]  

Expression of Carcinoembryonic Antigen and Nonspecific Cross-Reacting 50-kDa Antigen in Human Normal and Cancerous Colon Mucosa: Comparative Ultrastructural Study with Monoclonal Antibodies

Vladimir Baranov, Moorix Mo-Wai Yeung, and Sten Hammarström
Cancer Res 1994 54: 3305-3314. [Abstract] [PDF]  

Meeting Report:

Current Strategies of Cancer Chemoprevention: 13th Sapporo Cancer Seminar

Charles W. Boone and Lee W. Wattenberg
Cancer Res 1994 54: 3315-3318. [PDF]  

Letters to the Editor:

Correspondence re: S. E. Dew et al., Effects of Pharmacological Retinoids on Several Vitamin A-metabolizing Enzymes. Cancer Res., 53: 2965–2969, 1993.

Lonnie E. Allen and Michael H. Green
Cancer Res 1994 54: 3319 [PDF]  

Correspondence re: S. E. Dew et al., Effects of Pharmacological Retinoids on Several Vitamin A-metabolizing Enzymes. Cancer Res., 53: 2965–2969, 1993.—Reply

Stephanie E. Dew, Sarah A. Wardlaw, and David E. Ong
Cancer Res 1994 54: 3319-3320. [PDF]  

Articles:

Announcements

Cancer Res 1994 54: 3321-3323. [PDF]  

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