Advances in Brief:

Intravesical Gene Therapy: In Vivo Gene Transfer Using Recombinant Vaccinia Virus Vectors

Sharon S. Lee, Laurence C. Eisenlohr, Peter A. McCue, Michael J. Mastrangelo, and Edmund C. Lattime
Cancer Res 1994 54: 3325-3328. [Abstract] [PDF]  

Expression and Cellular Localization of Messenger RNA for Plasminogen Activator Inhibitor Type 1 in Human Astrocytomas in Vivo

Masaaki Yamamoto, Raymond Sawaya, Sanjeeva Mohanam, David J. Loskutoff, Janet M. Bruner, Velidi H. Rao, Kazunari Oka, Masamichi Tomonaga, Garth L. Nicolson, and Jasti S. Rao
Cancer Res 1994 54: 3329-3332. [Abstract] [PDF]  

Determination of Local Oxygen Consumption Rates in Tumors

Mark W. Dewhirst, Timothy W. Secomb, Edgardo T. Ong, Richard Hsu, and Joseph F. Gross
Cancer Res 1994 54: 3333-3336. [Abstract] [PDF]  

Surface Protein Expression and Messenger RNA-splicing Analysis of CD44 in Uterine Cervical Cancer and Normal Cervical Epithelium

Peter Dall, Karl-Heinz Heider, Armin Hekele, Gunther von Minckwitz, Manfred Kaufmann, Helmut Ponta, and Peter Herrlich
Cancer Res 1994 54: 3337-3341. [Abstract] [PDF]  

Polyvalent Melanoma Cell Vaccine Induces Delayed-Type Hypersensitivity and in Vitro Cellular Immune Response

Andreas Barth, Dave S. B. Hoon, Leland J. Foshag, J. Anne Nizze, Estela Famatiga, Edward Okun, and Donald L. Morton
Cancer Res 1994 54: 3342-3345. [Abstract] [PDF]  

The Selective Antiproliferative Effects of -Tocopheryl Hemisuccinate and Cholesteryl Hemisuccinate on Murine Leukemia Cells Result from the Action of the Intact Compounds

Marc W. Fariss, Michael B. Fortuna, Carieen K. Everett, J. Doyle Smith, David F. Trent, and Zora Djuric
Cancer Res 1994 54: 3346-3351. [Abstract] [PDF]  

Mirovascular Permeability and Interstitial Penetration of Sterically Stabilized (Stealth) Liposomes in a Human Tumor Xenograft

Fan Yuan, Michael Leunig, Shi Kun Huang, David A. Berk, Demetrios Papahadjopoulos, and Rakesh K. Jain
Cancer Res 1994 54: 3352-3356. [Abstract] [PDF]  

Tamoxifen Induces Hepatic Aneuploidy and Mitotic Spindle Disruption after a Single in Vivo Administration to Female Sprague-Dawley Rats

Linda M. Sargent, Yvonne P. Dragan, Nicole Bahnub, John E. Wiley, Carol A. Sattler, Pauline Schroeder, Gerald L. Sattler, V. Craig Jordan, and Henry C. Pitot
Cancer Res 1994 54: 3357-3360. [Abstract] [PDF]  

Concomitant p53 Gene Mutation and Increased Radiosensitivity in Rat Lung Embryo Epithelial Cells during Neoplastic Development

D. S. F. Biard, M. Martin, Y. Le Rhun, A. Duthu, J. L. Lefaix, E. May, and P. May
Cancer Res 1994 54: 3361-3364. [Abstract] [PDF]  

In Vivo Radiation Protection by Nitric Oxide Modulation

James Liebmann, Anne Marie DeLuca, Deborah Coffin, Larry K. Keefer, David Venzon, David A. Wink, and James B. Mitchell
Cancer Res 1994 54: 3365-3368. [Abstract] [PDF]  

Purification of an Class Glutathione S-Transferase from Melphalan-resistant Chinese Hamster Ovary Cells and Demonstration of Its Ability to Catalyze Melphalan-Glutathione Adduct Formation

Andrew G. Hall, Elizabeth Matheson, Ian D. Hickson, Sally A. Foster, and Linda Hogarth
Cancer Res 1994 54: 3369-3372. [Abstract] [PDF]  

Frequent Replication Errors at Microsatellite Loci in Tumors of Patients with Multiple Primary Cancers

Akira Horii, Hye-Jung Han, Mamoru Shimada, Akio Yanagisawa, Yo Kato, Hirotoshi Ohta, Wataru Yasui, Eiichi Tahara, and Yusuke Nakamura
Cancer Res 1994 54: 3373-3375. [Abstract] [PDF]  

Type and Number of Ki-ras Point Mutations Relate to Stage of Human Colorectal Cancer

Peter Moerkerk, Jan Willem Arends, Marjolein van Driel, Adriaan de Bruïne, Anton de Goeij, and Joop ten Kate
Cancer Res 1994 54: 3376-3378. [Abstract] [PDF]  

Microsatellite Instability Occurs Frequently and in Both Diploid and Aneuploid Cell Populations of Barrett's-associated Esophageal Adenocarcinomas

Stephen J. Meltzer, Jing Yin, Beth Manin, Mun-Gan Rhyu, John Cottrell, Eric Hudson, Jacquelyn L. Redd, Mark J. Krasna, John M. Abraham, and Brian J. Reid
Cancer Res 1994 54: 3379-3382. [Abstract] [PDF]  

Mutations in the Coding Region of c-MYC in AIDS-associated and Other Aggressive Lymphomas

Helen M. Clark, Takahiro Yano, Takemi Otsuki, Elaine S. Jaffe, Darryl Shibata, and Mark Raffeld
Cancer Res 1994 54: 3383-3386. [Abstract] [PDF]  

HER2/neu-derived Peptides Are Shared Antigens among Human Non-Small Cell Lung Cancer and Ovarian Cancer

Ichiro Yoshino, Peter S. Goedegebuure, George E. Peoples, Akhil S. Parikh, J. Michael DiMaio, H. Kim Lyerly, Adi F. Gazdar, and Timothy J. Eberlein
Cancer Res 1994 54: 3387-3390. [Abstract] [PDF]  

Induction of WAF1/CIP1 by a p53-independent Pathway

Paolo Michieli, Marcio Chedid, David Lin, Jacalyn H. Pierce, W. Edward Mercer, and David Givol
Cancer Res 1994 54: 3391-3395. [Abstract] [PDF]  

Frequent Somatic Mutation of the MTS1/CDK4I (Multiple Tumor Suppressor/Cyclin-dependent Kinase 4 Inhibitor) Gene in Esophageal Squamous Cell Carcinoma

Takahiro Mori, Koh Miura, Takahisa Aoki, Tetsuro Nishihira, Shozo Mori, and Yusuke Nakamura
Cancer Res 1994 54: 3396-3397. [Abstract] [PDF]  

REVIEWS:

Genetic Changes in Epithelial Solid Neoplasia

Eduardo Rodriguez, Chandrika Sreekantaiah, and R. S. K. Chaganti
Cancer Res 1994 54: 3398-3406. [Abstract] [PDF]  

Biochemistry and Biophysics:

A Fumagillin Derivative Angiogenesis Inhibitor, AGM-1470, Inhibits Activation of Cyclin-dependent Kinases and Phosphorylation of Retinoblastoma Gene Product but not Protein Tyrosyl Phosphorylation or Protooncogene Expression in Vascular Endothelial Cells

Jun'ichi Abe, Wei Zhou, Noriko Takuwa, Jun'ichi Taguchi, Kiyoshi Kurokawa, Mamoru Kumada, and Yoh Takuwa
Cancer Res 1994 54: 3407-3412. [Abstract] [PDF]  

Carcinogenesis:

Development and Characterization of Nontumorigenic and Tumorigenic Epithelial Cell Lines from Rat Dorsal-Lateral Prostate

David Danielpour, Kenji Kadomatsu, Mario A. Anzano, Joseph M. Smith, and Michael B. Sporn
Cancer Res 1994 54: 3413-3421. [Abstract] [PDF]  

Stable Expression of Human CYP1A2 and N-Acetyltransferases in Chinese Hamster CHL Cells: Mutagenic Activation of 2-Amino-3-methylimidazo[4,5-f]quinoline and 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline

Yoshiki Yanagawa, Minoru Sawada, Takeo Deguchi, Frank J. Gonzalez, and Tetsuya Kamataki
Cancer Res 1994 54: 3422-3427. [Abstract] [PDF]  

Inhibitory Effects of Black Tea, Green Tea, Decaffeinated Black Tea, and Decaffeinated Green Tea on Ultraviolet B Light-induced Skin Carcinogenesis in 7,12-Dimethylbenz[a]anthracene-initiated SKH-1 Mice

Zhi Y. Wang, Mou-Tuan Huang, You-Rong Lou, Jian-Guo Xie, Kenneth R. Reuhl, Harold L. Newmark, Chi-Tang Ho, Chung S. Yang, and Allan H. Conney
Cancer Res 1994 54: 3428-3435. [Abstract] [PDF]  

Clinical Investigations:

Phase Ib Trial of Pentoxifylline and Ciprofloxacin in Patients Treated with Interleukin-2 and Lymphokine-activated Killer Cell Therapy for Metastatic Renal Cell Carcinoma

John A. Thompson, James A. Bianco, Mark C. Benyunes, Marcus A. Neubauer, John T. Slattery, and Alexander Fefer
Cancer Res 1994 54: 3436-3441. [Abstract] [PDF]  

Endocrinology:

Inhibition of Growth of Human Small Cell Lung Cancer by Bromocriptine

Miyuki Ishibashi, Michio Fujisawa, Hisashi Furue, Yoshiharu Maeda, Masashi Fukayama, and Tohru Yamaji
Cancer Res 1994 54: 3442-3446. [Abstract] [PDF]  

Regulation of Synthesis of the Transformation-induced Protein, Leukocyte Plastin, by Ovarian Steroid Hormones

John Leavitt, Zong Ping Chen, Charles J. Lockwood, and Frederick Schatz
Cancer Res 1994 54: 3447-3454. [Abstract] [PDF]  

Expression and Localization of Somatostatin Receptor SSTR1, SSTR2, and SSTR3 Messenger RNAs in Primary Human Tumors using in Situ Hybridization

J. C. Reubi, J. C. Schaer, B. Waser, and G. Mengod
Cancer Res 1994 54: 3455-3459. [Abstract] [PDF]  

Experimental Therapeutics:

B3(Fab)-PE38^M: A Recombinant Immunotoxin in Which a Mutant Form of Pseudomonas Exotoxin Is Fused to the Fab Fragment of Monoclonal Antibody B3

MuHyeon Choe, Keith O. Webber, and Ira Pastan
Cancer Res 1994 54: 3460-3467. [Abstract] [PDF]  

Biochemical Pharmacology of Homologous Alicyclic Mixed Amine Platinum(II) Complexes in Sensitive and Resistant Tumor Cell Lines

Motofumi Yoshida, Abdul R. Khokhar, and Zahid H. Siddik
Cancer Res 1994 54: 3468-3473. [Abstract] [PDF]  

Enhancement of Merocyanine 540 Uptake and Photodynamic Cell Killing by Salicylates

Jimmy B. Feix, M. S. Anderson, and B. Kalyanaraman
Cancer Res 1994 54: 3474-3478. [Abstract] [PDF]  

In Vitro Evaluation of DNA-DNA Hybridization as a Two-Step Approach in Radioimmunotherapy of Cancer

Ebo S. Bos, Will H. A. Kuijpers, Marjolein Meesters-Winters, Diep T. Pham, Annemarie S. de Haan, Anton M. van Doornmalen, Frans M. Kaspersen, Constant A. A. van Boeckel, and Francoise Gougeon-Bertrand
Cancer Res 1994 54: 3479-3486. [Abstract] [PDF]  

Elevated DNA Polymerase , DNA Polymerase ß, and DNA Topoisomerase II in a Melphalan-resistant Rhabdomyosarcoma Xenograft That Is Cross-Resistant to Nitrosoureas and Topotecan

Henry S. Friedman, M. Eileen Dolan, Scott H. Kaufmann, O. Michael Colvin, Owen W. Griffith, Robert C. Moschel, S. Clifford Schold, Darell D. Bigner, and Francis Ali-Osman
Cancer Res 1994 54: 3487-3493. [Abstract] [PDF]  

Tributyrin: A Prodrug of Butyric Acid for Potential Clinical Application in Differentiation Therapy

Zi-Xing Chen and Theodore R. Breitman
Cancer Res 1994 54: 3494-3499. [Abstract] [PDF]  

Enhanced Replicative Bypass of Platinum-DNA Adducts in Cisplatin-resistant Human Ovarian Carcinoma Cell Lines

Edward L. Mamenta, Eric E. Poma, William K. Kaufmann, Dean A. Delmastro, Heather L. Grady, and Stephen G. Chaney
Cancer Res 1994 54: 3500-3505. [Abstract] [PDF]  

Enhancement of Tumor Radioresponse of a Murine Mammary Carcinoma by Paclitaxel

Luka Milas, Nancy R. Hunter, Kathryn A. Mason, Belma Kurdoglu, and Lester J. Peters
Cancer Res 1994 54: 3506-3510. [Abstract] [PDF]  

Immunology:

Human Monoclonal Antibody Identified an Immunoreactive Tetrapeptide Sequence (Lys-Tyr-Gln-Ile) in M_r 43,000 Protein of Human Melanoma

Takanori Oka, Yoshikazu Kikumoto, Keiichi Itakura, Donald L. Morton, and Reiko F. Irie
Cancer Res 1994 54: 3511-3515. [Abstract] [PDF]  

Immunotherapy of Bladder Cancer with Cytokine Gene-modified Tumor Vaccines

Shiro Saito, Rajat Bannerji, Bernd Gansbacher, Felicia M. Rosenthal, Peter Romanenko, Warren D. W. Heston, William R. Fair, and Eli Gilboa
Cancer Res 1994 54: 3516-3520. [Abstract] [PDF]  

Adenosine Inhibits the Adhesion of Anti-CD3-activated Killer Lymphocytes to Adenocarcinoma Cells through an A₃ Receptor

Willena M. MacKenzie, David W. Hoskin, and Jonathan Blay
Cancer Res 1994 54: 3521-3526. [Abstract] [PDF]  

Effect of Isotype on Internalization and Cytotoxicity of CD19-Ricin A Immunotoxins

Ypke V. J. M. van Oosterhout, Ingrid E. van den Herik-Oudijk, Hans M. C. Wessels, Theo de Witte, Jan G. J. van de Winkel, and Frank W. M. B. Preijers
Cancer Res 1994 54: 3527-3532. [Abstract] [PDF]  

Molecular Biology and Genetics:

Chromosomal Loss and Breakage in Mouse Bone Marrow and Spleen Cells Exposed to Benzene in Vivo

Hongwei Chen, Doppalapudi S. Rupa, Rajpal Tomar, and David A. Eastmond
Cancer Res 1994 54: 3533-3539. [Abstract] [PDF]  

Limonene Chemoprevention of Mammary Carcinoma Induction following Direct in Situ Transfer of v-Ha-ras

Michael N. Gould, Cynthia J. Moore, Rong Zhang, Bingcheng Wang, Wendy S. Kennan, and Jill D. Haag
Cancer Res 1994 54: 3540-3543. [Abstract] [PDF]  

Alterations in ß-Catenin Phosphorylation and Plakoglobin Expression in Human Breast Cancer Cells

Connie L. Sommers, Edward P. Gelmann, Rolf Kemler, Pamela Cowin, and Stephen W. Byers
Cancer Res 1994 54: 3544-3552. [Abstract] [PDF]  

Association of APC Gene Mutations and Histological Characteristics of Colorectal Adenomas

Laura De Benedetti, Stefani Sciallero, Viviana Gismondi, Rosella James, Anna Bafico, Roberta Biticchi, Emiliana Masetti, Luigina Bonelli, Abdelhamid Heouaine, Massimo Picasso, Joanna Groden, Margaret Robertson, Mauro Risio, Renzo Caprilli, Paolo Bruzzi, Raymond L. White, Hugo Aste, Leonardo Santi, Liliana Varesco, and Giovanni Battista Ferrara
Cancer Res 1994 54: 3553-3556. [Abstract] [PDF]  

Telomere Shortening Associated with Disease Evolution Patterns in Myelodysplastic Syndromes

Junko H. Ohyashiki, Kazuma Ohyashiki, Toshikatsu Fujimura, Ken Kawakubo, Takashi Shimamoto, Atsuhiro Iwabuchi, and Keisuke Toyama
Cancer Res 1994 54: 3557-3560. [Abstract] [PDF]  

Loss of Amplified c-myc Genes in the Spontaneously Differentiated HL-60 Cells

Noriaki Shimizu, Hitoshi Nakamura, Takumi Kadota, Kenji Kitajima, Tsukasa Oda, Tetsuo Hirano, and Hiroyasu Utiyama
Cancer Res 1994 54: 3561-3567. [Abstract] [PDF]  

Detection of K-ras Mutations in the Stool of Patients with Pancreatic Adenocarcinoma and Pancreatic Ductal Hyperplasia

Carlos Caldas, Stephan A. Hahn, Ralph H. Hruban, Mark S. Redston, Charles J. Yeo, and Scott E. Kern
Cancer Res 1994 54: 3568-3573. [Abstract] [PDF]  

Potential Markers of Prostate Cancer Aggressiveness Detected by Fluorescence in Situ Hybridization in Needle Biopsies

Satoru Takahashi, Junqi Qian, James A. Brown, Antonio Alcaraz, David G. Bostwick, Michael M. Lieber, and Robert B. Jenkins
Cancer Res 1994 54: 3574-3579. [Abstract] [PDF]  

Tumor Biology:

Differential Expression of Nuclear Retinoid Receptors in Normal, Premalignant, and Malignant Head and Neck Tissues

Xiao-Chun Xu, Jae Y. Ro, Jin S. Lee, Dong M. Shin, Waun K. Hong, and Reuben Lotan
Cancer Res 1994 54: 3580-3587. [Abstract] [PDF]  

Mutations in the Conserved Regions of p53 Are Infrequent in Betel-associated Oral Cancers from Papua New Guinea

S. Thomas, J. Brennan, G. Martel, I. Frazer, R. Montesano, D. Sidransky, and M. Hollstein
Cancer Res 1994 54: 3588-3593. [Abstract] [PDF]  

Castration Induces Apoptosis in the Ventral Prostate but not in an Androgensensitive Prostatic Adenocarcinoma in the Rat

Anna Brändström, Patrick Westin, Anders Bergh, Stefan Cajander, and Jan-Erik Damber
Cancer Res 1994 54: 3594-3601. [Abstract] [PDF]  

Effects of Neuropeptide Analogues on Calcium Flux and Proliferation in Lung Cancer Cell Lines

Paul A. Bunn, Jr., Daniel Chan, John Stewart, Lajos Gera, Russell Tolley, Philip Jewett, Maureen Tagawa, Charlotte Alford, Tohru Mochzuki, and Noboru Yanaihara
Cancer Res 1994 54: 3602-3610. [Abstract] [PDF]  

Autocrine Factor Enhancing the Secretion of M_r 95,000 Gelatinase (Matrix Metalloproteinase 9) in Serum-free Medium Conditioned with Murine Metastatic Colon Carcinoma Cells

Sumiko Hyuga, Yohko Nishikawa, Keita Sakata, Hidekazu Tanaka, Sadako Yamagata, Kenji Sugita, Shinsuke Saga, Mutsushi Matsuyama, and Satoru Shimizu
Cancer Res 1994 54: 3611-3616. [Abstract] [PDF]  

Anticarcinogenic Activity of Indole-3-carbinol Acid Products: Ultrasensitive Bioassay by Trout Embryo Microinjection

Roderick H. Dashwood, Arthur T. Fong, Daniel N. Arbogast, Leonard F. Bjeldanes, Jerry D. Hendricks, and George S. Bailey
Cancer Res 1994 54: 3617-3619. [Abstract] [PDF]  

A Modified Invasion-3-(4,5-Dimethylthiazole-2-yl)-2,5-diphenyltetrazolium Bromide Assay for Quantitating Tumor Cell Invasion

Hiroshi Imamura, Sonshin Takao, and Takashi Aikou
Cancer Res 1994 54: 3620-3624. [Abstract] [PDF]  

Meeting Report:

Quantitative Estimation and Prediction of Risk at the International Agency for Research on Cancer

Henrik Møller and Elisabeth Heseltine
Cancer Res 1994 54: 3625-3627. [PDF]  

Articles:

Announcements

Cancer Res 1994 54: 3628-3631. [PDF]  

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