Advances in Brief:

Immunochemical Detection of the Multidrug Resistance-associated Protein MRP in Human Multidrug-resistant Tumor Cells by Monoclonal Antibodies

Marcel J. Flens, Miguel A. Izquierdo, George L. Scheffer, Jan M. Fritz, Chris J. L. M. Meijer, Rik J. Scheper, and Guido J. R. Zaman
Cancer Res 1994 54: 4557-4563. [Abstract] [PDF]  

Vascular Permeability and Microcirculation of Gliomas and Mammary Carcinomas Transplanted in Rat and Mouse Cranial Windows

Fan Yuan, Hassan A. Salehi, Yves Boucher, Usha S. Vasthare, Ronald F. Tuma, and Rakesh K. Jain
Cancer Res 1994 54: 4564-4568. [Abstract] [PDF]  

Ultraviolet Radiation-induced Malignant Skin Melanoma in Melanoma-susceptible Transgenic Mice

Andres J. P. Klein-Szanto, Willys K. Silvers, and Beatrice Mintz
Cancer Res 1994 54: 4569-4572. [Abstract] [PDF]  

Enzymatic Characteristics of Chimeric mYc/rYc₁ Glutathione S-Transferases

Kirk P. Van Ness, Timo M. Buetler, and David L. Eaton
Cancer Res 1994 54: 4573-4575. [Abstract] [PDF]  

A Monoclonal Antibody to Human Angiogenin Suppresses Tumor Growth in Athymic Mice

Karen A. Olson, Thayer C. French, Bert L. Vallee, and James W. Fett
Cancer Res 1994 54: 4576-4579. [Abstract] [PDF]  

Introduction of a Disulfide Bond in the 1 Domain of the H-2K^b Molecule Confers Immunogenicity to the Transfected RMA-S Tumors

Krishna V. Kesari and Jan Geliebter
Cancer Res 1994 54: 4580-4585. [Abstract] [PDF]  

Loss of Heterozygosity in Sporadic Human Breast Carcinoma: A Common Region between 11q22 and 11q23.3

Garret M. Hampton, Arto Mannermaa, Robert Winquist, Martti Alavaikko, Guillermo Blanco, Pentti J. Taskinen, Heikki Kiviniemi, Irene Newsham, Webster K. Cavenee, and Glen A. Evans
Cancer Res 1994 54: 4586-4589. [Abstract] [PDF]  

hMSH2 Mutations in Hereditary Nonpolyposis Colorectal Cancer Kindreds

Bo Liu, Ramon E. Parsons, Stanley R. Hamilton, Gloria M. Petersen, Henry T. Lynch, Patrice Watson, Sanford Markowitz, James K.V. Willson, Jane Green, Albert de la Chapelle, Kenneth W. Kinzler, and Bert Vogelstein
Cancer Res 1994 54: 4590-4594. [Abstract] [PDF]  

Microsatellite Instability in the Progression of Gastric Carcinoma

Ja-Mun Chong, Masashi Fukayama, Yukiko Hayashi, Touichirou Takizawa, Morio Koike, Motoko Konishi, Rei Kikuchi-Yanoshita, and Michiko Miyaki
Cancer Res 1994 54: 4595-4597. [Abstract] [PDF]  

Isolation of Differentially Expressed Sequence Tags from Human Breast Cancer

Mark A. Watson and Timothy P. Fleming
Cancer Res 1994 54: 4598-4602. [Abstract] [PDF]  

Infrequent Inactivation of the Retinoblastoma Gene Despite Frequent Loss of Chromosome 13q in Head and Neck Squamous Cell Carcinoma

George H. Yoo, Hong-Ji Xu, Joseph A. Brennan, William Westra, Ralph H. Hruban, Wayne Koch, William F. Benedict, and David Sidransky
Cancer Res 1994 54: 4603-4606. [Abstract] [PDF]  

Tamoxifen Restores the E-Cadherin Function in Human Breast Cancer MCF-7/6 Cells and Suppresses Their Invasive Phenotype

Marc E. Bracke, Corinne Charlier, Erik A. Bruyneel, Caroline Labit, Marc M. Mareel, and Vincent Castronovo
Cancer Res 1994 54: 4607-4609. [Abstract] [PDF]  

Specific Types of Human Papillomavirus Found in Benign Proliferations and Carcinomas of the Skin in Immunosuppressed Patients

Vladimir Shamanin, Mary Glover, Christine Rausch, Charlotte Proby, Irene M. Leigh, Harald zur Hausen, and Ethel-Michele de Villiers
Cancer Res 1994 54: 4610-4613. [Abstract] [PDF]  

Prevention of Breast Cancer in the Rat with 9-cis-Retinoic Acid as a Single Agent and in Combination with Tamoxifen

Mario A. Anzano, Stephen W. Byers, Joseph M. Smith, Christopher W. Peer, Larry T. Mullen, Charles C. Brown, Anita B. Roberts, and Michael B. Sporn
Cancer Res 1994 54: 4614-4617. [Abstract] [PDF]  

Biochemistry and Biophysics:

Down-Regulation of Topoisomerase I in Mammalian Cells following Ionizing Radiation

David A. Boothman, Nina Fukunaga, and Meizhi Wang
Cancer Res 1994 54: 4618-4626. [Abstract] [PDF]  

Depletion of Nuclear Poly(ADP-Ribose) Polymerase by Antisense RNA Expression: Influences on Genomic Stability, Chromatin Organization, and Carcinogen Cytotoxicity

Ruchuang Ding and Mark Smulson
Cancer Res 1994 54: 4627-4634. [Abstract] [PDF]  

Carcinogenesis:

Comparison of 7,12-Dimethylbenz(a)anthracene-DNA Adduction in the Epidermis of Two Lines of Mice Selected for Resistance (CAR-R) or Susceptibility (CAR-S) to Skin Carcinogenesis

François Perin, Odette Perin, Nicole Barat, Marie-José Plessis, Anna Saran, Claudio Pioli, Vincenzo Covelli, Guido Biozzi, and Denise Mouton
Cancer Res 1994 54: 4635-4640. [Abstract] [PDF]  

Effects of Green Tea and Black Tea on 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Bioactivation, DNA Methylation, and Lung Tumorigenesis in A/J Mice

Stephanie Tao Shi, Zhi-Yuan Wang, Theresa J. Smith, Jun-Yan Hong, Wu-Feng Chen, Chi-Tang Ho, and Chung S. Yang
Cancer Res 1994 54: 4641-4647. [Abstract] [PDF]  

Rapid Repair of O⁶-Methylguanine-DNA Adducts Protects Transgenic Mice from N-Methylnitrosourea-induced Thymic Lymphomas

Lili Liu, Esther Allay, Luba L. Dumenco, and Stanton L. Gerson
Cancer Res 1994 54: 4648-4652. [Abstract] [PDF]  

Chemoprevention of 4-Nitroquinoline 1-Oxide-induced Oral Carcinogenesis by Dietary Curcumin and Hesperidin: Comparison with the Protective Effect of ß-Carotene

Takuji Tanaka, Hiroki Makita, Masami Ohnishi, Yoshinobu Hirose, Aijin Wang, Hideki Mori, Kumiko Satoh, Akira Hara, and Hiroshi Ogawa
Cancer Res 1994 54: 4653-4659. [Abstract] [PDF]  

Clinical Investigations:

Plasma Kinetics and Biodistribution of a Lipid Emulsion Resembling Low-Density Lipoprotein in Patients with Acute Leukemia

Raul C. Maranhão, Bernardo Garicochea, Edson L. Silva, Pedro Dorlhiac-Llacer, Silvia M. S. Cadena, Iris J. C. Coelho, José Claudio Meneghetti, Fulvio J. C. Pileggi, and Dalton A. F. Chamone
Cancer Res 1994 54: 4660-4666. [Abstract] [PDF]  

Prognostic Significance of p53 Overexpression in Endometrial Cancer

Kiyoshi Ito, Keiko Watanabe, Suhail Nasim, Hironobu Sasano, Shinji Sato, Akira Yajima, Steven G. Silverberg, and Carleton T. Garrett
Cancer Res 1994 54: 4667-4670. [Abstract] [PDF]  

Prognostic Impact of Urokinase, Urokinase Receptor, and Type 1 Plasminogen Activator Inhibitor in Squamous and Large Cell Lung Cancer Tissue

Helle Pedersen, Nils Brünner, Dorthe Francis, Kell Østerlind, Ebbe Rønne, Heine Høi Hansen, Keld Danø, and Jan Grøndahl-Hansen
Cancer Res 1994 54: 4671-4675. [Abstract] [PDF]  

Analysis of Multidrug Resistance-associated Protein (MRP) Messenger RNA in Normal and Malignant Hematopoietic Cells

Mohammad R. Abbaszadegan, Bernard W. Futscher, Walter T. Klimecki, Alan List, and William S. Dalton
Cancer Res 1994 54: 4676-4679. [Abstract] [PDF]  

Epidemiology:

Increased Birth Weights of National Wilms' Tumor Study Patients Suggest a Growth Factor Excess

W. M. Leisenring, N. E. Breslow, I. E. Evans, J. B. Beckwith, M. J. Coppes, and P. Grundy
Cancer Res 1994 54: 4680-4683. [Abstract] [PDF]  

Experimental Therapeutics:

In Vitro and in Vivo Antitumor Activity of ZENECA ZD0490, a Recombinant Ricin A-Chain Immunotoxin for the Treatment of Colorectal Cancer

Joanne A. Calvete, David R. Newell, Andrew F. Wright, and Michael S. Rose
Cancer Res 1994 54: 4684-4690. [Abstract] [PDF]  

Axial Ligands and Alicyclic Ring Size Modulate the Activity and Biochemical Pharmacology of Ammine/Cycloalkylamine-Platinum(IV) Complexes in Tumor Cells Resistant to cis-Diamminedichloroplatinum(II) or trans-1R,2R-1S,2S-Diaminocyclohexanetetrachloroplatinum(IV)

Motofumi Yoshida, Abdul R. Khokhar, and Zahid H. Siddik
Cancer Res 1994 54: 4691-4697. [Abstract] [PDF]  

Effect of 1,19-Bis(ethylamino)-5,10,15-triazanonadecane on Human Tumor Xenografts

M. Eileen Dolan, Matthew J. Fleig, Burt G. Feuerstein, Hirak S. Basu, Gordon D. Luk, Robert A. Casero, Jr., and Laurence J. Marton
Cancer Res 1994 54: 4698-4702. [Abstract] [PDF]  

Epidermal Growth Factor Receptors in Human Breast Carcinoma Cells: A Potential Selective Target for Transforming Growth Factor -Pseudomonas Exotoxin 40 Fusion Protein

Carlos L. Arteaga, Stephen D. Hurd, Teresa C. Dugger, Angela R. Winnier, and J. Bruce Robertson
Cancer Res 1994 54: 4703-4709. [Abstract] [PDF]  

Intrathecal Melphalan Therapy of Human Neoplastic Meningitis in Athymic Nude Rats

Henry S. Friedman, Gerald E. Archer, Roger E. McLendon, James M. Schuster, O. Michael Colvin, Al Guaspari, Robert Blum, Paul A. Savina, Herbert E. Fuchs, and Darell D. Bigner
Cancer Res 1994 54: 4710-4714. [Abstract] [PDF]  

Inhibition of Angiogenesis by the Matrix Metalloprotease Inhibitor N-[2R-2-(Hydroxamidocarbonymethyl)-4-methylpentanoyl)]-L-tryptophan Methylamide

Richard E. Galardy, Damian Grobelny, Harald G. Foellmer, and Leonardo A. Fernandez
Cancer Res 1994 54: 4715-4718. [Abstract] [PDF]  

Radioimmunotherapy of Neoplastic Meningitis in Rats Using an -Particle-emitting Immunoconjugate

Michael R. Zalutsky, Roger E. McLendon, Pradeep K. Garg, Gary E. Archer, James M. Schuster, and Darell D. Bigner
Cancer Res 1994 54: 4719-4725. [Abstract] [PDF]  

Matrix Metalloproteinase Inhibitor BB-94 (Batimastat) Inhibits Human Colon Tumor Growth and Spread in a Patient-like Orthotopic Model in Nude Mice

X. Wang, X. Fu, P. D. Brown, M. J. Crimmin, and R. M. Hoffman
Cancer Res 1994 54: 4726-4728. [Abstract] [PDF]  

Immunology:

Suppressive Effect of Basic Fibroblast Growth Factor on Transendothelial Emigration of CD4(+) T-Lymphocyte

Joji Kitayama, Hirokazu Nagawa, Hiroshi Yasuhara, Nelson Tsuno, Wataru Kimura, Yoichi Shibata, and Tetsuichiro Muto
Cancer Res 1994 54: 4729-4733. [Abstract] [PDF]  

T-Cell Receptor Repertoire of Lymphocytes Infiltrating Cutaneous Melanoma Is Predominated by V Specificities Present in T-Cells of Normal Human Skin

Robert Strohal, Ljubomir Paucz, Hubert Pehamberger, and Georg Stingl
Cancer Res 1994 54: 4734-4739. [Abstract] [PDF]  

Colony-Stimulating Activity and Hematopoietic Rescue from Cancer Chemotherapy Compounds Are Induced by Melatonin via Endogenous Interleukin 4

Georges J. M. Maestroni, Ario Conti, and Paolo Lissoni
Cancer Res 1994 54: 4740-4743. [Abstract] [PDF]  

Molecular Biology and Genetics:

Expression of Thyroid-specific Transcription Factors TTF-1 and PAX-8 in Human Thyroid Neoplasms

Dora Fabbro, Carla Di Loreto, Carlo Alberto Beltrami, Antonino Belfiore, Roberto Di Lauro, and Giuseppe Damante
Cancer Res 1994 54: 4744-4749. [Abstract] [PDF]  

p53 Mutations and Microsatellite Instability in Sporadic Gastric Cancer: When Guardians Fail

John G. Strickler, Jian Zheng, Qiuping Shu, Lawrence J. Burgart, Steven R. Alberts, and Darryl Shibata
Cancer Res 1994 54: 4750-4755. [Abstract] [PDF]  

Basal Cell Carcinomas and Squamous Cell Carcinomas of Human Skin Show Distinct Patterns of Chromosome Loss

Anthony G. Quinn, Stephen Sikkink, and Jonathan L. Rees
Cancer Res 1994 54: 4756-4759. [Abstract] [PDF]  

The Putative Glioma Tumor Suppressor Gene on Chromosome 19q Maps between APOC2 and HRC

Mari-Paz Rubio, Katia M. Correa, Keisuke Ueki, Harvey W. Mohrenweiser, James F. Gusella, Andreas von Deimling, and David N. Louis
Cancer Res 1994 54: 4760-4763. [Abstract] [PDF]  

Comparative Genomic Hybridization in the Detection of DNA Copy Number Abnormalities in Uveal Melanoma

Kathleen B. Gordon, Curtis T. Thompson, Devron H. Char, Joan M. O'Brien, Stewart Kroll, Siavash Ghazvini, and Joe W. Gray
Cancer Res 1994 54: 4764-4768. [Abstract] [PDF]  

Tumor Biology:

NSP-encoded Reticulons Are Neuroendocrine Markers of a Novel Category in Human Lung Cancer Diagnosis

Helgi J. K. van de Velde, Nicole H. M. Senden, Tania A. D. Roskams, Jos L. V. Broers, Frans C. S. Ramaekers, Anton J. M. Roebroek, and Wim J. M. Van de Ven
Cancer Res 1994 54: 4769-4776. [Abstract] [PDF]  

Platelet-activating Factor Mediates an Autocrine Proliferative Loop in the Endometrial Adenocarcinoma Cell Line HEC-1A

Mario Maggi, Lorella Bonaccorsi, Giovanna Finetti, Vinicio Carloni, Monica Muratori, Giacomo Laffi, Gianni Forti, Mario Serio, and Elisabetta Baldi
Cancer Res 1994 54: 4777-4784. [Abstract] [PDF]  

Expression of Interleukin 1, Interleukin 6, and Tumor Necrosis Factor Genes in Human Melanoma Clones Is Associated with That of Mutated N-RAS Oncogene

Chiara Castelli, Marialuisa Sensi, Raffaella Lupetti, Roberta Mortarini, Pierangelo Panceri, Andrea Anichini, and Giorgio Parmiani
Cancer Res 1994 54: 4785-4790. [Abstract] [PDF]  

Overexpression of Metalloproteinase Inhibitor in B16F10 Cells Does Not Affect Extravasation but Reduces Tumor Growth

Sahadia Koop, Rama Khokha, Eric E. Schmidt, Ian C. MacDonald, Vincent L. Morris, Ann F. Chambers, and Alan C. Groom
Cancer Res 1994 54: 4791-4797. [Abstract] [PDF]  

A Frequent Alteration of p53 Gene in Carcinoma in Adenoma of Colon

Masayuki Ohue, Naohiro Tomita, Takushi Monden, Masami Fujita, Mutsumi Fukunaga, Koji Takami, Ikuo Yana, Tadashi Ohnishi, Takayuki Enomoto, Masaki Inoue, Takashi Shimano, and Takesada Mori
Cancer Res 1994 54: 4798-4804. [Abstract] [PDF]  

Modulation of Matrilysin Levels in Colon Carcinoma Cell Lines Affects Tumorigenicity in Vivo

Jean P. Witty, Susan McDonnell, Ken J. Newell, Paul Cannon, Marc Navre, Robert J. Tressler, and Lynn M. Matrisian
Cancer Res 1994 54: 4805-4812. [Abstract] [PDF]  

PRAD-1/Cyclin D1 Gene Amplification Correlates with Messenger RNA Overexpression and Tumor Progression in Human Laryngeal Carcinomas

Pedro Jares, Pedro L. Fernández, Elías Campo, Alfons Nadal, Francesc Bosch, Gemma Aiza, Iracema Nayach, José Traserra, and Antonio Cardesa
Cancer Res 1994 54: 4813-4817. [Abstract] [PDF]  

Articles:

Announcements

Cancer Res 1994 54: 4818-4821. [PDF]  

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