Advances in Brief:

Volume-activated Chloride Current Is Not Related to P-Glycoprotein Overexpression

Yan-jie Dong, Gang Chen, George E. Durán, Keisuke Kouyama, Anthony C. Chao, Branimir I. Sikic, Sastry V. Gollapudi, Sudhir Gupta, and Phyllis Gardner
Cancer Res 1994 54: 5029-5032. [Abstract] [PDF]  

Antitumor Effect of Ischemia-Reperfusion Injury Induced by Transient Embolization

Toshikazu Yoshikawa, Satoshi Kokura, Hirokazu Oyamada, Shoji Iinuma, Shunichiro Nishimura, Toshiro Kaneko, Yuji Naito, and Motoharu Kondo
Cancer Res 1994 54: 5033-5035. [Abstract] [PDF]  

Expression of the Multidrug Resistance-associated Protein (MRP) Gene Correlates with Amplification and Overexpression of the N-myc Oncogene in Childhood Neuroblastoma

Sharon B. Bordow, Michelle Haber, Janice Madafiglio, Belamy Cheung, Glenn M. Marshall, and Murray D. Norris
Cancer Res 1994 54: 5036-5040. [Abstract] [PDF]  

Loss of Maternal Alleles on Chromosome Arm 11p in Hepatoblastoma

Steffen Albrecht, Dietrich von Schweinitz, Andreas Waha, Jürgen A. Kraus, Andreas von Deimling, and Torsten Pietsch
Cancer Res 1994 54: 5041-5044. [Abstract] [PDF]  

Loss of Heterozygosity of Chromosome 9p21 Is Associated with the Immortal Phenotype of Neoplastic Human Head and Neck Keratinocytes

O. Loughran, K. G. Edington, I. J. Berry, L. J. Clark, and E. K. Parkinson
Cancer Res 1994 54: 5045-5049. [Abstract] [PDF]  

Higher Frequency of Alterations in the p16/CDKN2 Gene in Squamous Cell Carcinoma Cell Lines Than in Primary Tumors of the Head and Neck

Shi-Yu Zhang, Andres J. P. Klein-Szanto, Edward R. Sauter, Marianna Shafarenko, Shinichiro Mitsunaga, Tsutomu Nobori, Dennis A. Carson, John A. Ridge, and Tamra L. Goodrow
Cancer Res 1994 54: 5050-5053. [Abstract] [PDF]  

The p53-dependent G₁ Cell Cycle Checkpoint Pathway and Ataxia-Telangiectasia

Christine E. Canman, Antonio C. Wolff, Chaw-Yuan Chen, Albert J. Fornace, Jr, and Michael B. Kastan
Cancer Res 1994 54: 5054-5058. [Abstract] [PDF]  

Perspectives in Cancer Research:

Microsatellite Instability: Marker of a Mutator Phenotype in Cancer

Lawrence A. Loeb
Cancer Res 1994 54: 5059-5063. [PDF]  

Carcinogenesis:

Heterogeneity in the Mitotic Checkpoint Control of BALB/3T3 Cells and a Correlation with Gene Amplification Propensity

Maria G. DeWald, Rakesh C. Sharma, Andrew L. Kung, Hubert E. Wong, Steven W. Sherwood, and Robert T. Schimke
Cancer Res 1994 54: 5064-5070. [Abstract] [PDF]  

Chemoprevention of Azoxymethane-induced Colonic Carcinogenesis by Supplemental Dietary Ursodeoxycholic Acid

David L. Earnest, Hana Holubec, Ramesh K. Wali, Carolyn S. Jolley, Marc Bissonette, Achyut K. Bhattacharyya, Hemant Roy, Sharad Khare, and Thomas A. Brasitus
Cancer Res 1994 54: 5071-5074. [Abstract] [PDF]  

In Vitro Folate Deficiency Induces Deoxynucleotide Pool Imbalance, Apoptosis, and Mutagenesis in Chinese Hamster Ovary Cells

S. Jill James, Alexei G. Basnakian, and Barbara J. Miller
Cancer Res 1994 54: 5075-5080. [Abstract] [PDF]  

Potent Carcinogenicity of Uncovered Halogen Lamps in Hairless Mice

Francesco D'Agostini and Silvio De Flora
Cancer Res 1994 54: 5081-5085. [Abstract] [PDF]  

Identification of Frequent Novel Genetic Alterations in Small Cell Lung Carcinoma

Nikki A. Levin, Pius Brzoska, Nalin Gupta, John D. Minna, Joe W. Gray, and Michael F. Christman
Cancer Res 1994 54: 5086-5091. [Abstract] [PDF]  

Endocrinology:

A New Nude Mouse Model for Postmenopausal Breast Cancer Using MCF-7 Cells Transfected with the Human Aromatase Gene

Wei Yue, Dujin Zhou, Shiuan Chen, and Angela Brodie
Cancer Res 1994 54: 5092-5095. [Abstract] [PDF]  

Human Chorionic Gonadotropin (hCG) and Its Free Subunits in Hydrocele Fluids and Neoplastic Tissue of Testicular Cancer Patients: Insights into the in Vivo hCG Secretion Pattern

Stephan Madersbacher, Christian Kratzik, Regine Gerth, Stephan Dirnhofer, and Peter Berger
Cancer Res 1994 54: 5096-5100. [Abstract] [PDF]  

Epidemiology:

A Clinical and Epidemiological Study of Human Leukocyte Antigen-DPB Alleles in Hodgkin's Disease

Amit M. Oza, Susan Tonks, Jackie Lim, Marie A. Fleetwood, T. Andrew Lister, Julia G. Bodmer, and Collaborating Centers
Cancer Res 1994 54: 5101-5105. [Abstract] [PDF]  

Correlations of Chronic Hepatitis B Virus Infection and Cigarette Smoking with Elevated Expression of neu Oncoprotein in the Development of Hepatocellular Carcinoma

Ming-Whei Yu, Chien-Jen Chen, Jiin-Chyuan Luo, Paul W. Brandt-Rauf, Walter P. Carney, and Regina M. Santella
Cancer Res 1994 54: 5106-5110. [Abstract] [PDF]  

Experimental Therapeutics:

Radioimmunotherapy of Human B-Cell Chronic Lymphocytic Leukemia in Nude Mice

Zhenping Zhu, Tarunendu Ghose, David Hoskin, Christine L. Y. Lee, Louis A. Fernandez, Spencer H. S. Lee, and Molly Mammen
Cancer Res 1994 54: 5111-5117. [Abstract] [PDF]  

A Pharmacokinetic Model of Topotecan Clearance from Plasma and Cerebrospinal Fluid

Cynthia Sung, Susan M. Blaney, Diane E. Cole, Frank M. Balis, and Robert L. Dedrick
Cancer Res 1994 54: 5118-5122. [Abstract] [PDF]  

Metabolism of O⁶-Benzylguanine, an Inactivator of O⁶-Alkylguanine-DNA Alkyltransferase

M. Eileen Dolan, Mi-Young Chae, Anthony E. Pegg, John H. Mullen, Henry S. Friedman, and Robert C. Moschel
Cancer Res 1994 54: 5123-5130. [Abstract] [PDF]  

The Suppression of Drug-induced Apoptosis by Activation of v-ABL Protein Tyrosine Kinase

Rachel S. Chapman, Anthony D. Whetton, and Caroline Dive
Cancer Res 1994 54: 5131-5137. [Abstract] [PDF]  

Inhibition of Topoisomerase I Activity by Tyrphostin Derivatives, Protein Tyrosine Kinase Blockers: Mechanism of Action

Esther Aflalo, Seri Iftach, Shraga Segal, Aviv Gazit, and Esther Priel
Cancer Res 1994 54: 5138-5142. [Abstract] [PDF]  

Enhanced Suppression of Tumor Growth by Combination of Angiogenesis Inhibitor O-(Chloroacetyl-carbamoyl)fumagillol (TNP-470) and Cytotoxic Agents in Mice

Tetsuro Kato, Kazunari Sato, Hideaki Kakinuma, and Yukihisa Matsuda
Cancer Res 1994 54: 5143-5147. [Abstract] [PDF]  

Inhibition of HT-29 Human Colon Cancer Growth under the Renal Capsule of Severe Combined Immunodeficient Mice by an Analogue of 1,25-Dihydroxyvitamin D₃, DD-003

Yoko Tanaka, An-Ya S. Wu, Nobuo Ikekawa, Katsuhiko Iseki, Makoto Kawai, and Yoshiro Kobayashi
Cancer Res 1994 54: 5148-5153. [Abstract] [PDF]  

Small Chimeric Toxins Containing Only Transforming Growth Factor and Domain III of Pseudomonas Exotoxin with Good Antitumor Activity in Mice

Ako Kihara and Ira Pastan
Cancer Res 1994 54: 5154-5159. [Abstract] [PDF]  

Cell Cycle Studies of Cyclocreatine, a New Anticancer Agent

Katherine J. Martin, Elizabeth R. Winslow, and Rima Kaddurah-Daouk
Cancer Res 1994 54: 5160-5165. [Abstract] [PDF]  

Potentiation of 5-Fluorouracil Efficacy by the Dihydrouracil Dehydrogenase Inhibitor, 5-Benzyloxybenzyluracil

Fardos N. M. Naguib, Shao-Nan Hao, and Mahmoud H. el Kouni
Cancer Res 1994 54: 5166-5170. [Abstract] [PDF]  

Regression of Established Breast Carcinoma Xenografts with Antibody-directed Enzyme Prodrug Therapy against c-erbB2 p185

Suzanne A. Eccles, William J. Court, Gary A. Box, Christopher J. Dean, Roger G. Melton, and Caroline J. Springer
Cancer Res 1994 54: 5171-5177. [Abstract] [PDF]  

Immunology:

Establishment, Molecular Rescue, and Expression of 123AV16-1, a Tumor-reactive Human Monoclonal Antibody

Brenda L. Hall, James H. Murray, Martin V. Haspel, and Barry J. Kobrin
Cancer Res 1994 54: 5178-5185. [Abstract] [PDF]  

Murine Immune Response to Cells Transfected with Human MUC1: Immunization with Cellular and Synthetic Antigens

Vasso Apostolopoulos, Pei-Xiang Xing, and Ian F. C. McKenzie
Cancer Res 1994 54: 5186-5193. [Abstract] [PDF]  

Molecular Biology and Genetics:

Fibroblast Growth Factor-4 Enhanced G₂ Arrest and Cell Survival Following Ionizing Radiation

Mira Jung, Francis G. Kern, Timothy J. Jorgensen, Sandra W. McLeskey, Owen C. Blair, and Anatoly Dritschilo
Cancer Res 1994 54: 5194-5197. [Abstract] [PDF]  

Metastasizing Neuroblastomas in Mice Transgenic for Simian Virus 40 Large T (SV40T) under the Olfactory Marker Protein Gene Promoter

Bo Servenius, John Vernachio, Jennifer Price, Leif C. Andersson, and Per A. Peterson
Cancer Res 1994 54: 5198-5205. [Abstract] [PDF]  

Identification of a Novel Variant Form of Fibroblast Growth Factor Receptor 3 (FGFR3 IIIb) in Human Colonic Epithelium

Bernadette Murgue, Shoji Tsunekawa, Ian Rosenberg, Michelle deBeaumont, and Daniel K. Podolsky
Cancer Res 1994 54: 5206-5211. [Abstract] [PDF]  

Clonal Determination by the Fragile X (FMR1) and Phosphoglycerate Kinase (PGK) Genes in Hematological Malignancies

Siew-Teh Lee, Ronald C. McGlennen, and Craig E. Litz
Cancer Res 1994 54: 5212-5216. [Abstract] [PDF]  

Identification of Genes Overexpressed in Tumors through Preferential Expression Screening in Trophoblasts

Dorine Chassin, Jean-Louis Bénifla, Claire Delattre, Hervé Fernandez, Danièle Ginisty, Jean-Louis Janneau, Michel Prade, Geneviève Contesso, Bernard Caillou, Michel Tournaire, René Frydman, Dominique Elias, Pierre Bedossa, Jean-Michel Bidart, Dominique Bellet, and Ahmet Koman
Cancer Res 1994 54: 5217-5223. [Abstract] [PDF]  

Tumor Biology:

Ionizing Radiation Induces a Transient Increase in Cytosolic Free [Ca²⁺] in Human Epithelial Tumor Cells

Daniel G. Todd and Ross B. Mikkelsen
Cancer Res 1994 54: 5224-5230. [Abstract] [PDF]  

Metabolism of 4-Hydroxynonenal, a Cytotoxic Lipid Peroxidation Product, in Ehrlich Mouse Ascites Cells at Different Proliferation Stages

Tilman Grune, Werner G. Siems, Helmward Zollner, and Hermann Esterbauer
Cancer Res 1994 54: 5231-5235. [Abstract] [PDF]  

Identification of Genes Differentially Expressed in Normal Lung and Non-Small Cell Lung Carcinoma Tissue

Peter Schraml, Rob Shipman, Marco Colombi, and Christian U. Ludwig
Cancer Res 1994 54: 5236-5240. [Abstract] [PDF]  

Meeting Report:

Molecular Mechanisms of Progression and Metastasis of Human Tumors: A Pathology B Study Section Workshop: Working Report from the Division of Research Grants, NIH

Bonnie F. Sloane, Chester J. Herman, and Martin Padarathsingh
Cancer Res 1994 54: 5241-5245. [PDF]  

Articles:

Announcements

Cancer Res 1994 54: 5246-5248. [PDF]  

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